Profils Sociodemographique, Economique Et Alimentaire Chez Des Enfants Malnutris Aigus, Ages De 06 A 59 Mois, Reçus Au Centre Hospitalier Universitaire De Treichville (Abidjan-Cote D’ivoire)

In this descriptive and transversal work, the main objective is to establish the socio-demographic, economic and nutritional profiles of the children, aged between 06 and 59 months, acutely malnourished, consulted and / or hospitalized in pediatric emergency departments and Of the University Hospital of Treichville (UHT). This study is conducted on 290 children, aged between 06 and 59 months. A questioning anthropometric, socio-demographic, economic and food data allows the diagnosis of the nutritional status of each child and the descriptive statistical analysis of the patient. The results show that the prevalence of acute malnutrition is 55.86%, with 35.17 % cases of severe acute malnutrition and 20.68 % of cases of moderate acute malnutrition. The population of acute malnourished children in this study consisted of 84 girls and 78 boys, a sex ratio of 0.928. The children (133) victims of this type of malnutrition come, predominantly and significantly, from the precarious habitats. 126 have out-of-school mothers and 129 have consumed food of diversification or poor quality supplement. In 110 acute malnutrition, the daily family food budget is between 1500 FCFA and 3000 FCFA. At last, the index of food consumption score, also called food consumption, is referred to as a limit in 98. Finally, in this study, the risk factors having a significant impact on nutritional status are the precariousness of the habitat Place of residence), maternal education, complement food quality or diversification, food insecurity, age of complement and current diet

Access to water and sanitation infrastructures for primary schoolchildren in the south-central part of Côte d'Ivoire

In rural settings of Côte d'Ivoire, access to water, sanitation, and hygiene (WASH) at schools is often lacking. The purpose of this study was to assess the availability, quality, and use of WASH infrastructure in schools in the south-central part of Côte d'Ivoire, and to determine the hygiene practices of schoolchildren. A cross-sectional study was conducted in 20 primary schools with (n = 10) or without (n = 10) direct access to drinking water. The survey was comprised of a questionnaire directed at schoolchildren aged 8-17 years, an assessment of the WASH infrastructure, and the testing of drinking water samples for Escherichia coli and total coliforms. Overall, 771 schoolchildren were enrolled in the study. One out of four children (24.9%) reported that they used available toilets. Among those children not using toilets, more than half (57.5%) reported that they practised open defecation. Drinking water infrastructure was limited in most schools because of poor storage tanks, the low flow of water, or broken wells. All drinking water samples (n = 18) tested positive for total coliforms and 15 (83.3%) tested positive for E. coli. The lack of WASH infrastructures in primary schools in the south-central part of Côte d'Ivoire, in combination with poor hygiene practices, might govern disease transmission and absenteeism at school, especially among females

Evaluation des propriétés hydrauliques des aquifères fracturés des formations cristalline et métamorphique dans la région des Lacs (centre de la Côte d’Ivoire)

Groundwater is the main source of water supply for rural populations in the Region des Lacs area in central Côte d’Ivoire (West Africa). The area is underlain by the metamorphic and crystalline fractured hard rock aquifers. This paper focuses on the assessment of their hydraulic properties. To this end, a data base comprising pumping tests data and the technical reports were gathered. 105 values of transmissivity (T ) and specific capacity (Q/s) have been deduced after pumping tests interpretation by the Jacob recovery method. Statistical analyses of all these data have been done. Depth of wells range from 49.50 to 99 m with an average of 69 m. The thickness of the weathered zone has averaged 16.52 m and lies between 1.90 and 63.10 m. Wells average rate is 2.32 m3/s. The depths of open fractures are significantly in the first 60 meters of hard rock drilling and averaged 42.94 m. The transmissivity and specific capacity of each aquifer span over several orders of magnitude revealing the strong heterogeneity of the aquifer. Both variables are lognormal variables A significant empirical relationship between T and Q/s was found T = 0,937(Q/s)^1.118 with a coefficient of determination (R^2 = 0.82). This relationship enabled the transmissivity data to be supplemented with the 95% prediction interval in order to assess the uncertainty associated with the estimates of transmissivity in the area of the study. These results are significant and can be used as an input in forthcoming modeling these aquifers and facilitate groundwater management policy.[fr] Dans la région des Lacs, centre de la Côte d’Ivoire (Afrique de l’Ouest), l’alimentation en eau potable des populations rurales est assurée en majorité par les eaux souterraines contenues dans les aquifères discontinus cristallin et cristallophyllien. L’objet de cet article est d’évaluer les propriétés hydrauliques de ces aquifères afin d’entreprendre des études pour la gestion optimale de cette ressource. Pour ce faire, une compilation de données regroupant les fiches techniques de forage de même que les essais de pompage disponibles dans la région a été faite. L’interprétation des essais de pompage par la méthode de remontée de Jacob a permis de déterminer 105 valeurs de transmissivité (T ) et de débit spécifique (Q/s). Une analyse statistique des paramètres de forages et des paramètres hydrauliques déterminés a été réalisée. Les forages ont une profondeur totale qui varie de 49,50 à 99 m avec une moyenne de 69 m. L’épaisseur des altérites est comprise entre 1,90 et 63,10 m pour une moyenne de 16,52 m. Les forages ont un débit moyen de 2,32 m3/s. Les profondeurs de venues d’eau sont en moyenne de 42,94 m dans la roche non altérée. Les transmissivités et les débits spécifiques s’échelonnent sur trois ordres de grandeur avec des coefficients de variation supérieurs à 100% traduisant ainsi l’hétérogénéité structurale du milieu aquifère. Ces deux paramètres sont également distribués selon la loi log-normale au seuil de 10%. Une relation empirique significative entre la transmissivité et le débit spécifique a été établie. Elle permet d’estimer la transmissivité par l’expressionT = 0,937(Q/s)^1,118 avec R^2 = 0,82 dans un intervalle de confiance de 95% pour les aquifères de la zone d’étude. Ces résultats sont importants car, ils seront utiles dans les études de modélisation de ces aquifères et faciliteront la politique de gestion des eaux souterraines

A Trial of Early Antiretrovirals and Isoniazid Preventive Therapy in Africa

BACKGROUND: In sub-Saharan Africa, the burden of human immunodeficiency virus (HIV)-associated tuberculosis is high. We conducted a trial with a 2-by-2 factorial design to assess the benefits of early antiretroviral therapy (ART), 6-month isoniazid preventive therapy (IPT), or both among HIV-infected adults with high CD4+ cell counts in Ivory Coast. METHODS: We included participants who had HIV type 1 infection and a CD4+ count of less than 800 cells per cubic millimeter and who met no criteria for starting ART according to World Health Organization (WHO) guidelines. Participants were randomly assigned to one of four treatment groups: deferred ART (ART initiation according to WHO criteria), deferred ART plus IPT, early ART (immediate ART initiation), or early ART plus IPT. The primary end point was a composite of diseases included in the case definition of the acquired immunodeficiency syndrome (AIDS), non-AIDS-defining cancer, non-AIDS-defining invasive bacterial disease, or death from any cause at 30 months. We used Cox proportional models to compare outcomes between the deferred-ART and early-ART strategies and between the IPT and no-IPT strategies. RESULTS: A total of 2056 patients (41% with a baseline CD4+ count of ≥500 cells per cubic millimeter) were followed for 4757 patient-years. A total of 204 primary end-point events were observed (3.8 events per 100 person-years; 95% confidence interval [CI], 3.3 to 4.4), including 68 in patients with a baseline CD4+ count of at least 500 cells per cubic millimeter (3.2 events per 100 person-years; 95% CI, 2.4 to 4.0). Tuberculosis and invasive bacterial diseases accounted for 42% and 27% of primary end-point events, respectively. The risk of death or severe HIV-related illness was lower with early ART than with deferred ART (adjusted hazard ratio, 0.56; 95% CI, 0.41 to 0.76; adjusted hazard ratio among patients with a baseline CD4+ count of ≥500 cells per cubic millimeter, 0.56; 95% CI, 0.33 to 0.94) and lower with IPT than with no IPT (adjusted hazard ratio, 0.65; 95% CI, 0.48 to 0.88; adjusted hazard ratio among patients with a baseline CD4+ count of ≥500 cells per cubic millimeter, 0.61; 95% CI, 0.36 to 1.01). The 30-month probability of grade 3 or 4 adverse events did not differ significantly among the strategies. CONCLUSIONS: In this African country, immediate ART and 6 months of IPT independently led to lower rates of severe illness than did deferred ART and no IPT, both overall and among patients with CD4+ counts of at least 500 cells per cubic millimeter. (Funded by the French National Agency for Research on AIDS and Viral Hepatitis; TEMPRANO ANRS 12136 ClinicalTrials.gov number, NCT00495651.)

Effect of isoniazid preventive therapy on risk of death in west African, HIV-infected adults with high CD4 cell counts: long-term follow-up of the Temprano ANRS 12136 trial.

BACKGROUND: Temprano ANRS 12136 was a factorial 2 × 2 trial that assessed the benefits of early antiretroviral therapy (ART; ie, in patients who had not reached the CD4 cell count threshold used to recommend starting ART, as per the WHO guidelines that were the standard during the study period) and 6-month isoniazid preventive therapy (IPT) in HIV-infected adults in Côte d'Ivoire. Early ART and IPT were shown to independently reduce the risk of severe morbidity at 30 months. Here, we present the efficacy of IPT in reducing mortality from the long-term follow-up of Temprano. METHODS: For Temprano, participants were randomly assigned to four groups (deferred ART, deferred ART plus IPT, early ART, or early ART plus IPT). Participants who completed the trial follow-up were invited to participate in a post-trial phase. The primary post-trial phase endpoint was death, as analysed by the intention-to-treat principle. We used Cox proportional models to compare all-cause mortality between the IPT and no IPT strategies from inclusion in Temprano to the end of the follow-up period. FINDINGS: Between March 18, 2008, and Jan 5, 2015, 2056 patients (mean baseline CD4 count 477 cells per μL) were followed up for 9404 patient-years (Temprano 4757; post-trial phase 4647). The median follow-up time was 4·9 years (IQR 3·3-5·8). 86 deaths were recorded (Temprano 47 deaths; post-trial phase 39 deaths), of which 34 were in patients randomly assigned IPT (6-year probability 4·1%, 95% CI 2·9-5·7) and 52 were in those randomly assigned no IPT (6·9%, 5·1-9·2). The hazard ratio of death in patients who had IPT compared with those who did not have IPT was 0·63 (95% CI, 0·41 to 0·97) after adjusting for the ART strategy (early vs deferred), and 0·61 (0·39-0·94) after adjustment for the ART strategy, baseline CD4 cell count, and other key characteristics. There was no evidence for statistical interaction between IPT and ART (pinteraction=0·77) or between IPT and time (pinteraction=0·94) on mortality. INTERPRETATION: In Côte d'Ivoire, where the incidence of tuberculosis was last reported as 159 per 100 000 people, 6 months of IPT has a durable protective effect in reducing mortality in HIV-infected people, even in people with high CD4 cell counts and who have started ART. FUNDING: National Research Agency on AIDS and Viral Hepatitis (ANRS)

Drivers of diversification and pluriactivity among smallholder farmers—evidence from Nigeria

Diversification and pluriactivity have become a norm among farm business owners (FBOs) due to persistent low farm income. This study applies the resource-based theory to examine drivers of diversification and livelihood income-oriented towards a sustainable livelihood. Our framework develops hypotheses about the impact of internal and external resources on livelihood choices at the household level. We use a survey of 480 rural Nigerian farmers (agripreneurs), applying a Multivariate Tobit to test our framework. We find that education plays the most significant role in all types of employment options. The more FBOs are educated, the more the likelihood that they will choose non-farm or wage employment. This study revealed that while the agriculture sector’s share of rural employment is declining, non-farm is on the increase. More so, there is a decline in farming among the young generation, marital status bias and gender influence in resource allocation. The socioeconomic (income and food security) and socio-cultural (employment and rural-urban migration) implications of rural sustainability linked to UN Development Goals have been highlighted and analysed in this article

Quantitative estimates of glacial refugia for chimpanzees (Pan troglodytes) since the Last Interglacial (120,000 BP).

Paleoclimate reconstructions have enhanced our understanding of how past climates have shaped present-day biodiversity. We hypothesize that the geographic extent of Pleistocene forest refugia and suitable habitat fluctuated significantly in time during the late Quaternary for chimpanzees (Pan troglodytes). Using bioclimatic variables representing monthly temperature and precipitation estimates, past human population density data, and an extensive database of georeferenced presence points, we built a model of changing habitat suitability for chimpanzees at fine spatio-temporal scales dating back to the Last Interglacial (120,000 BP). Our models cover a spatial resolution of 0.0467° (approximately 5.19 km2 grid cells) and a temporal resolution of between 1000 and 4000 years. Using our model, we mapped habitat stability over time using three approaches, comparing our modeled stability estimates to existing knowledge of Afrotropical refugia, as well as contemporary patterns of major keystone tropical food resources used by chimpanzees, figs (Moraceae), and palms (Arecacae). Results show habitat stability congruent with known glacial refugia across Africa, suggesting their extents may have been underestimated for chimpanzees, with potentially up to approximately 60,000 km2 of previously unrecognized glacial refugia. The refugia we highlight coincide with higher species richness for figs and palms. Our results provide spatio-temporally explicit insights into the role of refugia across the chimpanzee range, forming the empirical foundation for developing and testing hypotheses about behavioral, ecological, and genetic diversity with additional data. This methodology can be applied to other species and geographic areas when sufficient data are available

The bii4africa dataset of faunal and floral population intactness estimates across Africa’s major land uses

Sub-Saharan Africa is under-represented in global biodiversity datasets, particularly regarding the impact of land use on species’ population abundances. Drawing on recent advances in expert elicitation to ensure data consistency, 200 experts were convened using a modified-Delphi process to estimate ‘intactness scores’: the remaining proportion of an ‘intact’ reference population of a species group in a particular land use, on a scale from 0 (no remaining individuals) to 1 (same abundance as the reference) and, in rare cases, to 2 (populations that thrive in human-modified landscapes). The resulting bii4africa dataset contains intactness scores representing terrestrial vertebrates (tetrapods: ±5,400 amphibians, reptiles, birds, mammals) and vascular plants (±45,000 forbs, graminoids, trees, shrubs) in sub-Saharan Africa across the region’s major land uses (urban, cropland, rangeland, plantation, protected, etc.) and intensities (e.g., large-scale vs smallholder cropland). This dataset was co-produced as part of the Biodiversity Intactness Index for Africa Project. Additional uses include assessing ecosystem condition; rectifying geographic/ taxonomic biases in global biodiversity indicators and maps; and informing the Red List of Ecosystems

Socializing One Health: an innovative strategy to investigate social and behavioral risks of emerging viral threats

In an effort to strengthen global capacity to prevent, detect, and control infectious diseases in animals and people, the United States Agency for International Development’s (USAID) Emerging Pandemic Threats (EPT) PREDICT project funded development of regional, national, and local One Health capacities for early disease detection, rapid response, disease control, and risk reduction. From the outset, the EPT approach was inclusive of social science research methods designed to understand the contexts and behaviors of communities living and working at human-animal-environment interfaces considered high-risk for virus emergence. Using qualitative and quantitative approaches, PREDICT behavioral research aimed to identify and assess a range of socio-cultural behaviors that could be influential in zoonotic disease emergence, amplification, and transmission. This broad approach to behavioral risk characterization enabled us to identify and characterize human activities that could be linked to the transmission dynamics of new and emerging viruses. This paper provides a discussion of implementation of a social science approach within a zoonotic surveillance framework. We conducted in-depth ethnographic interviews and focus groups to better understand the individual- and community-level knowledge, attitudes, and practices that potentially put participants at risk for zoonotic disease transmission from the animals they live and work with, across 6 interface domains. When we asked highly-exposed individuals (ie. bushmeat hunters, wildlife or guano farmers) about the risk they perceived in their occupational activities, most did not perceive it to be risky, whether because it was normalized by years (or generations) of doing such an activity, or due to lack of information about potential risks. Integrating the social sciences allows investigations of the specific human activities that are hypothesized to drive disease emergence, amplification, and transmission, in order to better substantiate behavioral disease drivers, along with the social dimensions of infection and transmission dynamics. Understanding these dynamics is critical to achieving health security--the protection from threats to health-- which requires investments in both collective and individual health security. Involving behavioral sciences into zoonotic disease surveillance allowed us to push toward fuller community integration and engagement and toward dialogue and implementation of recommendations for disease prevention and improved health security

Valeur nutritive et propriétés organoleptiques de l’attiéké, de l’attoukpou et du placali, trois mets à base de manioc, couramment consommés en Côte d’Ivoire

Objectif : Cette étude a été menée afin de constituer une base de données utile pour les spécifications nationales et les conseils nutritionnels. Ce travail a consisté à déterminer les propriétés organoleptiques et la valeur nutritive de l’"attiéké", de l’"attoukpou", et du "placali", trois mets à base de manioc, couramment consommés en Côte d’Ivoire.Méthodologie et résultats : Pour réaliser cette étude, une analyse physico-chimique de chaque mets préparé dans la localité de Bonoua a été réalisée. Ensuite une analyse sensorielle a été faite en réalisant un test descriptif et un test d’acceptabilité. L’analyse physico-chimique indique que l’"attiéké", l’"attoukpou" et le "placali" sont des aliments très énergétiques, essentiellement glucidiques. Ces mets ont de très faibles teneurs en protéines, lipides et cendres. Le potassium est le minéral le plus présent dans les trois mets. Leurs taux d’acide cyanhydrique sont légèrement supérieurs à la valeur standard de 1 mg/100 g recommandée par la FAO. Le "placali" est le plus acide (pH = 4,71) de ces mets. L’analyse sensorielle montre que l’"attiéké" se présente sous forme de semoule de grains détachés, l’"attoukpou" est composé de granules de manioc accolés et le "placali" se présente sous forme de pâte gélatineuse. Ces mets ont le même arôme que la poudre de manioc. Le placali est le plus aigre des trois mets, qui sont tous les trois appréciés par les consommateurs.Conclusion et application des résultats : Ces résultats montrent que l’"attiéké", l’"attoukpou" et le "placali" constituent des sources énergétiques potentielles dans l’alimentation des ivoiriens. Cependant, Les valeurs de l’acide cyanhydrique incitent à accorder de l’intérêt aux traitements culinaires qui permettent de diminuer la teneur en acide cyanhydrique. En outre, La forte teneur glucidique des mets à base de manioc étudiés ouvre une lucarne sur la prévalence à l’obésité et au diabète. D’où l’intérêt de la détermination de l’index et de la charge glycémique de ces mets.Mots-clés : manioc, attiéké, attoukpou, placali, valeurs nutritives, valeurs organoleptiques