4,419 research outputs found
Design of thrust vectoring exhaust nozzles for real-time applications using neural networks
Thrust vectoring continues to be an important issue in military aircraft system designs. A recently developed concept of vectoring aircraft thrust makes use of flexible exhaust nozzles. Subtle modifications in the nozzle wall contours produce a non-uniform flow field containing a complex pattern of shock and expansion waves. The end result, due to the asymmetric velocity and pressure distributions, is vectored thrust. Specification of the nozzle contours required for a desired thrust vector angle (an inverse design problem) has been achieved with genetic algorithms. This approach is computationally intensive and prevents the nozzles from being designed in real-time, which is necessary for an operational aircraft system. An investigation was conducted into using genetic algorithms to train a neural network in an attempt to obtain, in real-time, two-dimensional nozzle contours. Results show that genetic algorithm trained neural networks provide a viable, real-time alternative for designing thrust vectoring nozzles contours. Thrust vector angles up to 20 deg were obtained within an average error of 0.0914 deg. The error surfaces encountered were highly degenerate and thus the robustness of genetic algorithms was well suited for minimizing global errors
Evaluation of direct current motors in vacuum
Simulated space environment evaluation of direct current motor material
Fractional Quantum Hall Effect and vortex lattices
It is demonstrated that all observed fractions at moderate Landau level
fillings for the quantum Hall effect can be obtained without recourse to the
phenomenological concept of composite fermions. The possibility to have the
special topologically nontrivial many-electron wave functions is considered.
Their group classification indicates the special values of of electron density
in the ground states separated by a gap from excited states
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Women's interpretation of and responses to potential gynaecological cancer symptoms: a qualitative interview study
OBJECTIVE: To explore women's experiences of symptoms potentially indicative of gynaecological cancer in a community-based sample without imposing a cancer perspective.
DESIGN: A qualitative interview study with thematic analysis of transcripts.
PARTICIPANTS: 26 women aged ≥30 years, who had experienced a symptom that might indicate gynaecological cancer in the past 3 months, were recruited using a screening questionnaire distributed online and in community settings.
SETTING: London, UK.
RESULTS: Women attributed gynaecological symptoms to existing illnesses/conditions or considered themselves to be predisposed to them, either through their 'genes' or previous personal experience. Normalising symptoms by attributing them to demographic characteristics (e.g., age, sex) was common, as was considering them a side effect of hormonal contraception. When women raised cancer as a possible cause, they often dismissed it as unlikely. Responses to symptoms included self-management (e.g., self-medicating, making lifestyle changes), adopting a 'lay system of care', or consulting a healthcare professional. Triggers to help-seeking included persistent, painful or debilitating symptoms, concern about symptom seriousness, and feeling that help-seeking was legitimised. Barriers to help-seeking included lack of concern, vague symptoms, unusual symptom location, competing time demands, previous negative experiences with the healthcare system, and not wanting to be perceived as a time-waster.
CONCLUSIONS: Attributions of symptoms potentially indicative of a gynaecological cancer were varied, but most often involved women fitting symptoms into their expectations of what was 'normal'. Normalising acted as a barrier to seeking help from a healthcare professional, alongside competing time demands and negative attitudes towards help-seeking. These barriers may lead to later diagnosis and poorer cancer survival. Our findings could be used to inform the development of interventions to encourage appropriate help-seeking
Lens Model and Time Delay Predictions for the Sextuply Lensed Quasar SDSS J2222+2745
SDSS J2222+2745 is a galaxy cluster at z=0.49, strongly lensing a quasar at
z=2.805 into six widely separated images. In recent HST imaging of the field,
we identify additional multiply lensed galaxies, and confirm the sixth quasar
image that was identified by Dahle et al. (2013). We used the Gemini North
telescope to measure a spectroscopic redshift of z=4.56 of one of the secondary
lensed galaxies. These data are used to refine the lens model of SDSS
J2222+2745, compute the time delay and magnifications of the lensed quasar
images, and reconstruct the source image of the quasar host and a second lensed
galaxy at z=2.3. This second galaxy also appears in absorption in our Gemini
spectra of the lensed quasar, at a projected distance of 34 kpc. Our model is
in agreement with the recent time delay measurements of Dahle et al. (2015),
who found tAB=47.7+/-6.0 days and tAC=-722+/-24 days. We use the observed time
delays to further constrain the model, and find that the model-predicted time
delays of the three faint images of the quasar are tAD=502+/-68 days,
tAE=611+/-75 days, and tAF=415+/-72 days. We have initiated a follow-up
campaign to measure these time delays with Gemini North. Finally, we present
initial results from an X-ray monitoring program with Swift, indicating the
presence of hard X-ray emission from the lensed quasar, as well as extended
X-ray emission from the cluster itself, which is consistent with the lensing
mass measurement and the cluster velocity dispersion.Comment: 16 pages, 11 figures; submitted to Ap
Energetic particles observed by ISEE-1 and ISEE-2 in a cusp diamagnetic cavity on 29 September 1978
International audienceObservations by the ISEE-1 and ISEE-2 spacecraft on 29 September 1978 show large CEP (Cusp Energetic Particle) fluxes while passing through the dayside magnetospheric cusp in near coincident orbits. The event was observed around 11:00 MLT between roughly 12:30 and 13:00 UT by ISEE-1 and 12:00 and 13:00 UT by ISEE-2. During these periods, both electron and ion fluxes increased by more than two orders of magnitude, with the electron flux showing a strong peak at a pitch angle of 90°. The solar wind was ~710 km s?1 and the Dst was ~?200 nT, suggesting the occurrence of a strong geomagnetic storm. The ISEE-1 and ISEE-2 observations, however, show no time-energy dispersion of the CEPs, leading us to believe that these particles could not be the result of substorm processes in the magnetotail. The local magnetic field was depressed and extremely turbulent. Changes in the magnitude of the magnetic field anticorrelate closely to variations of the electron flux. The observations in electron flux peaking at 90° and the close anticorrelation between the local magnetic field strength and electron flux are unique and provide evidence of a potential local source for these energetic particles
The Interstellar Medium of Quiescent Galaxies and its Evolution With Time
We characterise the basic far-IR (FIR) properties and the gas mass fraction
of massive ( ~ 11.0) quiescent galaxies (QGs) and explore how
these evolve from z = 2.0 to the present day. We use robust, multi-wavelength
(mid- to far-IR and sub-millimetre to radio) stacking ensembles of
homogeneously selected and mass complete samples of log(M*/Msun) > 10.8 QGs. We
find that the dust to stellar mass ratio (Md/M*) rises steeply as a function of
redshift up to z~1.0 and then remains flat at least out to z = 2.0. Using Md as
a proxy of gas mass (Mgas), we find a similar trend for the evolution of the
gas mass fraction (fgas) with z > 1.0 QGs having fgas ~ 7.0% (for solar
metallicity). This fgas is 3 - 10 times lower than that of normal star forming
galaxies (SFGs) at their corresponding redshift but ~3 and ~10 times larger
compared to that of z = 0.5 and local QGs. Furthermore, the inferred gas
depletion time scales are comparable to that of local SFGs and systematically
longer than that of main sequence galaxies at their corresponding redshifts.
Our analysis also reveals that the average dust temperature (Td) of massive QGs
remains roughly constant ( = 21.0 \pm 2.0K) at least out to z ~ 2.0 and
is substantially colder (~ 10K) compared to that of z > 0 SFGs. This motivated
us to construct and release a redshift-invariant template IR SED, that we use
to make predictions for ALMA observations and to explore systematic effects in
the Mgas estimates of massive, high-z QGs. Finally, we discuss how a simple
model that considers progenitor-bias can effectively reproduce the observed
evolution of Md/M* and fgas. Our results indicate universal initial
interstellar medium conditions for quenched galaxies and a large degree of
uniformity in their internal processes across cosmic time.Comment: Accepted for publication in A&
Biochemical prediction of response of bone metastases to treatment.
Assessment of response of skeletal metastases to systemic therapy is currently dependent on radiological evidence of bone healing. We have performed a prospective study of additional response criteria in patients with progressive bone metastases from breast cancer. Changes in these potential markers of response were correlated with the radiological response and the time to treatment failure (TTF). Successful systemic therapy typically led to a transient increase in osteoblast activity ('flare'), a reduction in osteoclast activity and symptomatic improvement. After 1 month a greater than 10% rise in serum osteocalcin (BGP) and alkaline phosphatase bone isoenzyme (ALP-BI) and a greater than 10% fall in urinary calcium excretion were seen in 14/16 patients with radiographic evidence of bone healing (UICC partial responders). In comparison similar biochemical changes at 1 month were seen in only 4/20 patients with progressive disease (P less than 0.001). The predictive value and diagnostic efficiency (DE) of changes at 1 month in biochemical measurements and symptom score has been calculated. The combination of a greater than 10% rise in ALPBI and BGP and a greater than 10% fall in urinary calcium excretion had a DE of 89% for discriminating response from progression, 88% for response from non-response (progressing + no change patients), and 76% for TTF of greater than 6 months from TTF of less than 6 months. Serum calcium, tartrate resistant acid phosphatase (TRP), urinary hydroxyproline excretion and bone scan changes were unhelpful in discriminating between patient groups. Independent confirmation is needed, but our results suggest there are reliable alternatives to plain radiography in the early assessment of response of bone metastases to treatment
Star Formation at at z = 2.481 in the Lensed Galaxy SDSS J1110+6459. II. What is Missed at the Normal Resolution of the Hubble Space Telescope?
For lensed galaxy SGAS J111020.0+645950.8 at redshift z = 2.481, which is magnified by a factor of 28 ± 8, we analyze the morphology of star formation, as traced by rest-frame ultraviolet emission, in both the highly magnified source plane and simulations of how this galaxy would appear without lensing magnification. Were this galaxy not lensed, but rather drawn from a Hubble Space Telescope deep field, we would conclude that almost all its star formation arises from an exponential disk (Sérsic index of 1.0 ± 0.4) with an effective radius of r[subscript e]=2.7 ± 0.3 measured from two-dimensional fitting to F606W using Galfit, and r[subscript e]=1.9 ± 0.1 kpc measured by fitting a radial profile to F606W elliptical isophotes. At the normal spatial resolution of the deep fields, there is no sign of clumpy star formation within SGAS J111020.0+645950.8. However, the enhanced spatial resolution enabled by gravitational lensing tells a very different story; much of the star formation arises in two dozen clumps with sizes of r = 30–50 pc spread across the 7 kpc length of the galaxy. The color and spatial distribution of the diffuse component suggests that still-smaller clumps are unresolved. Despite this clumpy, messy morphology, the radial profile is still well-characterized by an exponential profile. In this lensed galaxy, stars are forming in complexes with sizes well below 100 pc; such sizes are wholly unexplored by surveys of galaxy evolution at 1 < z < 3
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