Аналіз факторів залучення та збереження уваги користувачів в інтернет-середовищі

The article specifies the essence of the processes of attracting and retaining the attention of users when interacting with a multimedia product on the Internet. The interrelation of volumes of the information and attention of users is grounded. The elements of the information structure of a multimedia product are generalized. Classified factors of attracting and retaining the attention of users in the Internet environment.У статті уточнено сутність процесів залучення і утримання уваги користувачів при взаємодії з мультимедійним продуктом в Інтернеті. Обґрунтовано взаємозв'язок обсягів інформації та уваги користувачів. Узагальнено елементи інформаційної структури мультимедійного продукту. Класифіковано чинники залучення і утримання уваги користувачів в Інтернет середовищі

MICE SERUM CYTOKINE LEVEL UNDER MUCOSAL IMMUNIZATION WITH OPPORTUNISTIC MICROBIAL ANTIGENS

An important parameter of immunotropic preparation effect is the influence on the production of cytokines that provide the interaction between the effectors of both congenital and adaptive immunity. Cytokine level was determined in the work while using the methods of mucosal immunization with Immunovac-VP-4 and compared with the subcutaneous introduction of this preparation. In case of intranasal and peroral methods of antigen application IL-5, IL-6, and IL-12 expression was found to be elevated, the same was true for IL-1β, IL-5, IL-6, IL-12, and IFN-γ under the subcutaneous immunization. Resulting mice cytokine profile confirmed that irrespective of the method of Immunovac introduction, the activation of immune effectors occurred that was manifested in the increase in proinflammatory and regulatory cytokine levels. It was concluded that the introduction of opportunistic microbial antigens initiated the activation of the cascade of immunologic reactions and under the influence of synthesized cytokines the polarization of immune response was involved that was predominantly of Th1 type

A System for Information Management in BioMedical Studies—SIMBioMS

Summary: SIMBioMS is a web-based open source software system for managing data and information in biomedical studies. It provides a solution for the collection, storage, management and retrieval of information about research subjects and biomedical samples, as well as experimental data obtained using a range of high-throughput technologies, including gene expression, genotyping, proteomics and metabonomics. The system can easily be customized and has proven to be successful in several large-scale multi-site collaborative projects. It is compatible with emerging functional genomics data standards and provides data import and export in accepted standard formats. Protocols for transferring data to durable archives at the European Bioinformatics Institute have been implemented

MORPHOFUNCTIONAL PECULIARITIES OF MUCOSAL IMMUNITY DEPENDING ON METHODS OF OPPORTUNISTIC MICROBIAL INTRODUCTION

Immunophenotypic and morphological peculiarities of immune reactions under intranasal, peroral and subcutaneous introduction of multicomponent vaccine Immunovac VP-4 containing a group of opportunistic bacterial antigens were investigated. The investigated preparation was found to cause marked activation of congenital immunity effectors both in parenteral and mucosal immunization. It is manifested in the expression of differential, costimulatory, adhesive molecules on the surface of mononuclear leukocytes in proliferation of key mucosal immunity effectors (γδТ, В1, NK cells), and changes in structure, cellular composition of immunocompetent organs both regional and distant as to the site of introduction. Currently existing data on effects and mechanisms of vaccine and immunomodulator mucosal introduction allows considering the development of mucosal mono- and associated vaccines as the priority direction in modern vaccinology

Impact of Cultivating Environment on the Terms of Persistence and Certain Properties of Cholera Vibrios

Objective of the study is to investigate the impact of cultivating temperature and medium on the terms of persistence, ctx gene retention, and enzymatic activity of V. cholerae O1 with various toxigenicity.Materials and methods. Utilized were the strains of V. cholerae El Tor: P-5879, P-19613, and also the strain P-19787.Results and conclusions. In the process of studying cholera vibrios El Tor with different genetic characteristics it was determined that the longest terms of persistence (19 days) on mineral substrates at 5 ºC were observed for toxigenic strains, while for non-toxigenic ones it made less than 17 days. At the same time cholera vibrios can persist continuously and even reproduce on mineral substrates under the conditions of subnormal lowered temperatures (not less than 10 °C). Toxigenic strains of Vibrio cholerae, irrespectively of cultivating medium and temperature, retained ctx gene in their genome and maintained enzymatic activity throughout the experiment. Such long-term persistence of cholera vibrios at low temperatures on mineral substrates may be regarded as possibility of preservation of V. cholerae toxigenic strains in case of import by the infected persons or vibrio-carriers

APLIKASI MANAJEMEN KEGIATAN UNTUK ORGANISASI NON PROFIT BERBASIS WEBSITE

Suatu organisasi memiliki berbagai program kerja, yang di dalamnya ada kepanitian khusus. Biasanya manajemen kegiatan yang berisi pengelolaan keuangan pada masing-masing organisasi dan lembaga dikepalai oleh bendahara. Pengelolaan keuangan tersebut menjadi sebuah kebutuhan, karena bendahara tersebut wajib selalu melaporkan pencatatan keuangan. Tentu akan menjadi tidak efektif jika melakukan pencatatan keuangan harus melakukannya secara manual. Di samping susah, pencatatan secara manual sangat beresiko seperti rusak dan hilangnya buku pencatatan. Ada lagi pencatatan dengan cara lain yaitu menggunakan software yang sudah ada seperti Microsoft Excel, namun hal tersebut masih kurang efisien dan kurang efektif sehingga diperlukan tools pencatatan yang lebih baik agar mencapai tujuan dan sasaran yang diinginkan. Subjek penelitian yang dibahas pada penelitian ini adalah aplikasi pengelolaan keuangan untuk organisasi non profit berbasis website. Langkah pengembangan aplikasi yaitu menggunakan waterfall model. Dari penelitian yang dilakukan menghasilkan sebuah website tentang ”aplikasi manajemen kegiatan untuk organisasi non profit berbasis website” yang dapat digunakan untuk melakukan manajemen kegiatan bagi organisasi non profit sehingga pekerjaan seorang bendahara menjadi mudah dan efektif.Keywords: Manajemen Kegiatan, Nonprofit Online, Organisasi Non Profit