36 research outputs found

    THE EFFECTS OF TEMPERATURE DEPENDENT VISCOSITY AND VISCOUS DISSIPATION ON MHD CONVECTION FLOW FROM AN ISOTHERMAL HORIZONTAL CIRCULAR CYLINDER IN THE PRESENCE OF STRESS WORK AND HEAT GENERATION

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    Temperature dependent viscosity and Viscous Dissipation effects are considered on hydromagnetic natural convection flow from horizontal circular cylinder immersed in an electrically conducting fluid with viscosity proportional to a linear function of temperature in the presence of stress work and heat generation. The partial differential governing equations are transformed to dimensionless forms. The numerical computations are carried out for several values of physical parameters involved in the transformed equations. The resulting nonlinear system of partial differential equations is solved numerically by Keller box method which is an implicit finite difference technique with Newton's linearization method. The features of the flow and heat transfer characteristics for different values of the governing parameters are analyzed and discussed. To support the accuracy of the numerical results, a comparison is made with known results from the open literature for some particular cases of the present study and the results are found to be in good agreement

    Can dissonance engineering improve risk analysis of human–machine systems?

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    The paper discusses dissonance engineering and its application to risk analysis of human–machine systems. Dissonance engineering relates to sciences and technologies relevant to dissonances, defined as conflicts between knowledge. The richness of the concept of dissonance is illustrated by a taxonomy that covers a variety of cognitive and organisational dissonances based on different conflict modes and baselines of their analysis. Knowledge control is discussed and related to strategies for accepting or rejecting dissonances. This acceptability process can be justified by a risk analysis of dissonances which takes into account their positive and negative impacts and several assessment criteria. A risk analysis method is presented and discussed along with practical examples of application. The paper then provides key points to motivate the development of risk analysis methods dedicated to dissonances in order to identify the balance between the positive and negative impacts and to improve the design and use of future human–machine system by reinforcing knowledge

    Stress-Induced Reinstatement of Drug Seeking: 20 Years of Progress

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    In human addicts, drug relapse and craving are often provoked by stress. Since 1995, this clinical scenario has been studied using a rat model of stress-induced reinstatement of drug seeking. Here, we first discuss the generality of stress-induced reinstatement to different drugs of abuse, different stressors, and different behavioral procedures. We also discuss neuropharmacological mechanisms, and brain areas and circuits controlling stress-induced reinstatement of drug seeking. We conclude by discussing results from translational human laboratory studies and clinical trials that were inspired by results from rat studies on stress-induced reinstatement. Our main conclusions are (1) The phenomenon of stress-induced reinstatement, first shown with an intermittent footshock stressor in rats trained to self-administer heroin, generalizes to other abused drugs, including cocaine, methamphetamine, nicotine, and alcohol, and is also observed in the conditioned place preference model in rats and mice. This phenomenon, however, is stressor specific and not all stressors induce reinstatement of drug seeking. (2) Neuropharmacological studies indicate the involvement of corticotropin-releasing factor (CRF), noradrenaline, dopamine, glutamate, kappa/dynorphin, and several other peptide and neurotransmitter systems in stress-induced reinstatement. Neuropharmacology and circuitry studies indicate the involvement of CRF and noradrenaline transmission in bed nucleus of stria terminalis and central amygdala, and dopamine, CRF, kappa/dynorphin, and glutamate transmission in other components of the mesocorticolimbic dopamine system (ventral tegmental area, medial prefrontal cortex, orbitofrontal cortex, and nucleus accumbens). (3) Translational human laboratory studies and a recent clinical trial study show the efficacy of alpha-2 adrenoceptor agonists in decreasing stress-induced drug craving and stress-induced initial heroin lapse

    A Preference-based framework for medical decision making.

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    International audienceMedical decision making, such as choosing which drugs to prescribe, requires to consider mandatory constraints, e.g. absolute contraindications, but also preferences that may not be satisfiable, e.g. guideline recommendations or patient preferences. The major problem is that these preferences are complex, numerous and come from various sources. The considered criteria are often conflicting and the number of decisions is too large to be explicitly handled. In this paper, we propose a framework for encoding medical preferences using a new connective, called ordered disjunction symbolized by ~×. Intuitively, the preference "Diuretic~×Betablocker means: "Prescribe a Diuretic if possible, but if this is not possible, then prescribe a Betablocker". We give an inference method for reasoning about the preferences and we show how this framework can be applied to a part of a guideline for hypertension

    A Preference-based framework for medical decision making.

    No full text
    International audienceMedical decision making, such as choosing which drugs to prescribe, requires to consider mandatory constraints, e.g. absolute contraindications, but also preferences that may not be satisfiable, e.g. guideline recommendations or patient preferences. The major problem is that these preferences are complex, numerous and come from various sources. The considered criteria are often conflicting and the number of decisions is too large to be explicitly handled. In this paper, we propose a framework for encoding medical preferences using a new connective, called ordered disjunction symbolized by ~×. Intuitively, the preference "Diuretic~×Betablocker means: "Prescribe a Diuretic if possible, but if this is not possible, then prescribe a Betablocker". We give an inference method for reasoning about the preferences and we show how this framework can be applied to a part of a guideline for hypertension

    Preprocessing rough network data for intrusion detection purposes

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    Observed TIME Difference of Arrival Based Position Estimation for LTE Systems: Simulation Framework and Performance Evaluation

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    Precise user equipment (UE) location is paramount for the reliable operation of location-based services provided by mobile network operators and other emerging applications. In this paper, the Long Term Evolution (LTE) network positioning performance based on mobile assist Observed Time Difference of Arrival (OTDoA) method is considered. The received signal time difference (RSTD) measurements are estimated by the UE using dedicated position reference signal (PRS) transmitted in the downlink frame where the reported time measurements are used by the network for location calculation. A simulation framework for the position estimation in LTE networks is presented where the LTE downlink communication link is implemented. The correlation-based method for the time of arrival measurement is used for the implementation of OTDoA. The simulation framework provides different configurations and adjustments for the system and network parameters for evaluating the performance of LTE positioning using OTDoA over multipath fading channels. Different simulation scenarios are conducted to identify the influence of various parameters of LTE system and positioning procedure setup on the positioning accuracy. Simulation results demonstrated that the positioning accuracy is highly affected by the channel fading condition where the accuracy of time of arrival measurements is deteriorated in severe fading environments; however, the positioning accuracy can be significantly improved by increasing the positioning sequences involved in the estimation process either in the frequency domain or in the time domain

    Effects of pressure stress work and thermal radiation on free convection flow around a sphere embedded in a porous medium with Newtonian heating

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    The effects of pressure stress work and thermal radiation on free convection flow around a sphere embedded in a porous medium with Newtonian heating is considered. The basic equations of boundary-layer are transformed into a non-dimensional form and reduced to non-linear system of partial differential equations and solved numerically using an implicit finite difference technique with Newtons linearization method. Comparisons with previously published work are performed and excellent agreement is obtained. Numerical results have been shown graphically and tabular forms for some selected values of parameters set consisting of radiation parameter, pressure stress work parameter, Newtonian heating coefficient, and Prandtl number
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