6,319 research outputs found
Development of a non-linear simulation for generic hypersonic vehicles - ASUHS1
A nonlinear simulation is developed to model the longitudinal motion of a vehicle in hypersonic flight. The equations of motion pertinent to this study are presented. Analytic expressions for the aerodynamic forces acting on a hypersonic vehicle which were obtained from Newtonian Impact Theory are further developed. The control surface forces are further examined to incorporate vehicle elastic motion. The purpose is to establish feasible equations of motion which combine rigid body, elastic, and aeropropulsive dynamics for use in nonlinear simulations. The software package SIMULINK is used to implement the simulation. Also discussed are issues needing additional attention and potential problems associated with the implementation (with proposed solutions)
Canonical Equivalence of a Generic 2D Dilaton Gravity Model and a Bosonic String Theory
We show that a canonical tranformation converts, up to a boundary term, a
generic 2d dilaton gravity model into a bosonic string theory with a
Minkowskian target space.Comment: LaTeX file, 9 pages, no figure
Diffeomorphisms, Noether Charges and Canonical Formalism in 2D Dilaton Gravity
We carry out a parallel study of the covariant phase space and the
conservation laws of local symmetries in two-dimensional dilaton gravity. Our
analysis is based on the fact that the Lagrangian can be brought to a form that
vanishes on-shell giving rise to a well-defined covariant potential for the
symplectic current. We explicitly compute the symplectic structure and its
potential and show that the requirement to be finite and independent of the
Cauchy surface restricts the asymptotic symmetries.Comment: 14 pages, latex with psfig macro, one figur
Molecular Hydrogen Kinematics in Cepheus A
We present the radial velocity structure of the molecular hydrogen outflows
associated to the star forming region Cepheus A. This structure is derived from
doppler shift of the H_2 v=1-0 S(1) emission line obtained by Fabry-Perot
spectroscopy. The East and West regions of emission, called Cep A(E) and Cep
A(W), show radial velocities in the range -20 to 0 km/s with respect to the
molecular cloud. Cep A(W) shows an increasing velocity with position offset
from the core indicating the existence of a possible accelarating machanism.
Cep A(E) has an almost constant mean radial velocity of -18 km/s along the
region although with a large dispersion in velocity, indicating the possibility
of a turbulent outflow. A detailed analysis of the Cep A(E) region shows
evidence for the presence of a Mach disk on that outflow. Also, we argue that
the presence of a velocity gradient in Cep A(W) is indicative of a C-shock in
this region. Following Riera et al. (2003), we analyzed the data using wavelet
analysis to study the line width and the central radial velocity distributions.
We found that both outflows have complex spatial and velocity structures
characteristic of a turbulent flow.Comment: 24 pages, 15 figure
Age-related changes in the relationship between alcohol use and violence from early adolescence to young adulthood
BACKGROUND: Despite the accumulation of studies examining the link between alcohol use and violence, no studies to our knowledge have systematically set out to detect age-related differences in these relationships. This limitation inhibits important insights into the stability of the relationship between alcohol use and violence among youth across varying ages.
METHOD: Study findings are based on repeated, cross-sectional data collected annually as part of the National Survey on Drug Use and Health between 2002 and 2013. We combined a series of nationally representative cross-sections to provide a multi-year string of data that, in effect, reflects a nationally representative non-traditional cohort. We conducted logistic regression analyses to examine the cross-sectional association between non-binge and binge drinking and violent attacks among youth between ages 12 (2002) and 24/25 (2013).
RESULTS: With respect to the association between non-binge alcohol use and violence, the only significant relationship identified—while controlling for sociodemographic and drug use factors—was for youth at age 13 (2003; OR = 1.97, 95% CI = 1.04–3.72). For binge drinking, we identified a distinct pattern of results. Controlling for sociodemographic, drug use factors, and school enrollment, binge drinking was significantly associated with violence between ages 13 (2003) and 20 (2010) with the largest odds ratios observed during the early adolescent period.
CONCLUSIONS: Non-binge drinking is associated with violent behavior at age 13. Binge drinking was found to be associated with violence among youth through age 20; however, the relationship dissipates when youth arrive at the legal drinking age of 21
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Absence of an embryonic stem cell DNA methylation signature in human cancer.
BackgroundDifferentiated cells that arise from stem cells in early development contain DNA methylation features that provide a memory trace of their fetal cell origin (FCO). The FCO signature was developed to estimate the proportion of cells in a mixture of cell types that are of fetal origin and are reminiscent of embryonic stem cell lineage. Here we implemented the FCO signature estimation method to compare the fraction of cells with the FCO signature in tumor tissues and their corresponding nontumor normal tissues.MethodsWe applied our FCO algorithm to discovery data sets obtained from The Cancer Genome Atlas (TCGA) and replication data sets obtained from the Gene Expression Omnibus (GEO) data repository. Wilcoxon rank sum tests, linear regression models with adjustments for potential confounders and non-parametric randomization-based tests were used to test the association of FCO proportion between tumor tissues and nontumor normal tissues. P-values of < 0.05 were considered statistically significant.ResultsAcross 20 different tumor types we observed a consistently lower FCO signature in tumor tissues compared with nontumor normal tissues, with 18 observed to have significantly lower FCO fractions in tumor tissue (total n = 6,795 tumor, n = 922 nontumor, P < 0.05). We replicated our findings in 15 tumor types using data from independent subjects in 15 publicly available data sets (total n = 740 tumor, n = 424 nontumor, P < 0.05).ConclusionsThe results suggest that cancer development itself is substantially devoid of recapitulation of normal embryologic processes. Our results emphasize the distinction between DNA methylation in normal tightly regulated stem cell driven differentiation and cancer stem cell reprogramming that involves altered methylation in the service of great cell heterogeneity and plasticity
Exact Finite-Size-Scaling Corrections to the Critical Two-Dimensional Ising Model on a Torus
We analyze the finite-size corrections to the energy and specific heat of the
critical two-dimensional spin-1/2 Ising model on a torus. We extend the
analysis of Ferdinand and Fisher to compute the correction of order L^{-3} to
the energy and the corrections of order L^{-2} and L^{-3} to the specific heat.
We also obtain general results on the form of the finite-size corrections to
these quantities: only integer powers of L^{-1} occur, unmodified by logarithms
(except of course for the leading term in the specific heat); and the
energy expansion contains only odd powers of L^{-1}. In the specific-heat
expansion any power of L^{-1} can appear, but the coefficients of the odd
powers are proportional to the corresponding coefficients of the energy
expansion.Comment: 26 pages (LaTeX). Self-unpacking file containing the tex file and
three macros (indent.sty, eqsection.sty, subeqnarray.sty). Added discussions
on the results and new references. Version to be published in J. Phys.
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