Comparative analysis of physical development and functional capacity of different sports athletes during competition period

The aim of this study was to compare physical fitness of high performance canoeists, rowers, Greek-Roman style wrestlers, basketball players and skiers during their competition period. Indices of physical development, muscle and fat mass and their ratios were obtained. Single muscular contraction power (SMCP) and anaerobic alactic muscular power (AAMP) were also measured. The anaerobic glycolytic power (AGP) was estimated by ergometer. The Bosco methodology was used to estimate the activity of fast twitch fibres (FTF). The psychomotor response time (PRT) and movement frequency (MF) per 10 s were estimated and Roufier index (RI) was applied to measure functional capacity of circulatory and respiratory systems. The examination of athletes specialising in five different sports allowed for identification of the peculiarities of sports specialisation. The distinctive height, highest body weight and static hand power values characterised rowers and basketball players; while canoeists had the highest muscle mass. Only canoeists achieved high SMCP during the competition period. The SMCP of rowers and skiers was optimal, whereas the basketball players and wrestlers demonstrated an insufficient single muscular contraction power. The highest anaerobic alactic muscle power was observed in basketball players and canoeists, whereas in the muscles the basketball players and wrestlers the activity of FTF was insufficient. Though its parameters were approximate to endurance-trained rowers, they considerably fell behind those of canoeists. The functional capacity of circulatory and respiratory system of skiers was highest. The research revealed that the majority of indices of skiers and wrestlers’ physical fitness were lowest among the other studied athletes. Such results reflect their limited potential to achieve high results in international competitions

SHIRAZ: an automated histology image annotation system for zebrafish phenomics

Histological characterization is used in clinical and research contexts as a highly sensitive method for detecting the morphological features of disease and abnormal gene function. Histology has recently been accepted as a phenotyping method for the forthcoming Zebrafish Phenome Project, a large-scale community effort to characterize the morphological, physiological, and behavioral phenotypes resulting from the mutations in all known genes in the zebrafish genome. In support of this project, we present a novel content-based image retrieval system for the automated annotation of images containing histological abnormalities in the developing eye of the larval zebrafish

Long-term trends in submicron particle concentrations in a metropolitan area of the northeastern United States

Significant changes in emission sources have occurred in the northeastern United States over the past decade, due in part to the implementation of emissions standards, the introduction and addition of abatement technologies for road transport, changes in fuel sulfur content for road and non-road transport, as well as economic impacts of a major recession and differential fuel prices. These changes in emission scenarios likely affected the concentrations of airborne submicron particles. This study investigated the characteristics of 11–500 nm particle number concentrations and their size spectra in Rochester, NY during the past 15 years (2002 to 2016). The modal structure, diurnal, weekly and monthly patterns of particle number concentrations are analyzed. Long-term trends are quantified using seasonal-trend decomposition procedures based on “Loess”, Mann-Kendall regression with Theil-Sen slope and piecewise regression. Particle concentrations underwent significant (p < 0.05) downward trends. An annual decrease of −323 particles/cm3/y (−4.6%/y) was estimated for the total particle number concentration using Theil-Sen analysis. The trends were driven mainly by the decrease in particles in the 11–50 nm range (−181 particles/cm3/y; −4.7%/y). Slope changes were investigated annually and seasonally. Piecewise regression found different slopes for different portions of the overall period with the strongest declines between 2005 and 2011/2013, followed by small upward trends between 2013 and 2016 for most size bins, possibly representing increased vehicular traffic after the recovery from the 2008 recession

Knock-Down of Cathepsin D Affects the Retinal Pigment Epithelium, Impairs Swim-Bladder Ontogenesis and Causes Premature Death in Zebrafish

The lysosomal aspartic protease Cathepsin D (CD) is ubiquitously expressed in eukaryotic organisms. CD activity is essential to accomplish the acid-dependent extensive or partial proteolysis of protein substrates within endosomal and lysosomal compartments therein delivered via endocytosis, phagocytosis or autophagocytosis. CD may also act at physiological pH on small-size substrates in the cytosol and in the extracellular milieu. Mouse and fruit fly CD knock-out models have highlighted the multi-pathophysiological roles of CD in tissue homeostasis and organ development. Here we report the first phenotypic description of the lack of CD expression during zebrafish (Danio rerio) development obtained by morpholino-mediated knock-down of CD mRNA. Since the un-fertilized eggs were shown to be supplied with maternal CD mRNA, only a morpholino targeting a sequence containing the starting ATG codon was effective. The main phenotypic alterations produced by CD knock-down in zebrafish were: 1. abnormal development of the eye and of retinal pigment epithelium; 2. absence of the swim-bladder; 3. skin hyper-pigmentation; 4. reduced growth and premature death. Rescue experiments confirmed the involvement of CD in the developmental processes leading to these phenotypic alterations. Our findings add to the list of CD functions in organ development and patho-physiology in vertebrates

Investigations of importance higher harmonics description of nucleus 12C

ISSN 0024-2969 - neteisingas; nuo 2003 m. - ISSN 1648-8504Fizikos instituta

The features of low-lying 0+states of the 16O nucleus taking into account multi quantum excitations

Rusiškos žurnalo versijos ISSN 0044-0027Fizikos instituta

Higher harmonics and spectrum of O+ states of nucleus 12C

ISSN 0024-2969 - neteisingas; nuo 2003 m. - ISSN 1648-8504Fizikos instituta