7 research outputs found
Quantifying the Performance of Quantum Codes
We study the properties of error correcting codes for noise models in the
presence of asymmetries and/or correlations by means of the entanglement
fidelity and the code entropy. First, we consider a dephasing Markovian memory
channel and characterize the performance of both a repetition code and an error
avoiding code in terms of the entanglement fidelity. We also consider the
concatenation of such codes and show that it is especially advantageous in the
regime of partial correlations. Finally, we characterize the effectiveness of
the codes and their concatenation by means of the code entropy and find, in
particular, that the effort required for recovering such codes decreases when
the error probability decreases and the memory parameter increases. Second, we
consider both symmetric and asymmetric depolarizing noisy quantum memory
channels and perform quantum error correction via the five qubit stabilizer
code. We characterize this code by means of the entanglement fidelity and the
code entropy as function of the asymmetric error probabilities and the degree
of memory. Specifically, we uncover that while the asymmetry in the
depolarizing errors does not affect the entanglement fidelity of the five qubit
code, it becomes a relevant feature when the code entropy is used as a
performance quantifier.Comment: 21 pages, 10 figure
Protected subspaces in quantum information
Contains fulltext :
84157.pdf (preprint version ) (Open Access
Generating genomic platforms to study Candida albicans pathogenesis
The advent of the genomic era has made elucidating gene function on a large scale a pressing challenge. ORFeome collections, whereby almost all ORFs of a given species are cloned and can be subsequently leveraged in multiple functional genomic approaches, represent valuable resources toward this endeavor. Here we provide novel, genome-scale tools for the study of Candida albicans, a commensal yeast that is also responsible for frequent superficial and disseminated infections in humans. We have generated an ORFeome collection composed of 5099 ORFs cloned in a Gateway (TM) donor vector, representing 83% of the currently annotated coding sequences of C. albicans. Sequencing data of the cloned ORFs are available in the CandidaOrfDB database at http://candidaorfeome.eu. We also engineered 49 expression vectors with a choice of promoters, tags and selection markers and demonstrated their applicability to the study of target ORFs transferred from the C. albicans ORFeome. In addition, the use of the ORFeome in the detection of protein-protein interaction was demonstrated. Mating-compatible strains as well as Gateway (TM)-compatible two-hybrid vectors were engineered, validated and used in a proof of concept experiment. These unique and valuable resources should greatly facilitate future functional studies in C. albicans and the elucidation of mechanisms that underlie its pathogenicity
Generating genomic platforms to study Candida albicans pathogenesis
The advent of the genomic era has made elucidating gene function on a large scale a pressing challenge. ORFeome collections, whereby almost all ORFs of a given species are cloned and can be subsequently leveraged in multiple functional genomic approaches, represent valuable resources toward this endeavor. Here we provide novel, genome-scale tools for the study of Candida albicans, a commensal yeast that is also responsible for frequent superficial and disseminated infections in humans. We have generated an ORFeome collection composed of 5099 ORFs cloned in a Gatewayâą donor vector, representing 83% of the currently annotated coding sequences of C. albicans. Sequencing data of the cloned ORFs are available in the CandidaOrfDB database at http://candidaorfeome.eu. We also engineered 49 expression vectors with a choice of promoters, tags and selection markers and demonstrated their applicability to the study of target ORFs transferred from the C. albicans ORFeome. In addition, the use of the ORFeome in the detection of protein-protein interaction was demonstrated. Mating-compatible strains as well as Gatewayâą-compatible two-hybrid vectors were engineered, validated and used in a proof of concept experiment. These unique and valuable resources should greatly facilitate future functional studies in C. albicans and the elucidation of mechanisms that underlie its pathogenicity.status: publishe