Settlement history, land holdings and landscape change, Eyjafjallahreppur, Iceland

In this paper we focus on a region in south Iceland and assess the confidence with which it is possible to determine the changing patterns of settlement history for a region and relate it to contemporaneous land boundaries. For a geographically coherent group of up to 38 possible farm sites in the northern and western part of Eyjafjallahreppur, south Iceland, the timing of occupation and abandonment is assessed. In addition, boundaries of landholdings, probable status and inter-site relationships are identified. Currently only 10 sites are occupied. There is some uncertainty over the location of the earliest settlements, but after the 11th century, successful principle farm sites such as Dalur, Seljaland and Mörk remain in the same locations. As a result, recent data on landholdings combined with a knowledge of the form of landholding sub-division, offers insights into pre-modern times, with some data relevant to medieval times. An ‘abandoned frontier’ exists in the inland area of Þórsmörk, but abandonment is not restricted to the uplands; it has occurred throughout the region. Most desertion occurred before the cold phases of the Little Ice Age in the 18th century. Overall, much farm desertion can be attributed to landscape destruction as a result of river migration, but it is also biased towards small dependent farms often established for social reasons (such as the property requirement for marriage) and evidently insufficiently resourced for long term success in a changing physical environment

Degrees of success : evaluating the environmental impacts of long term settlement in South Iceland.

This paper focuses on the occupation and landscape history of Dalur and Mörk, two areas of long-term settlement in the Eyjafjallahreppur district of southern Iceland. The aim is to illustrate the importance of evaluating not only farm occupation and abandonment, but also to assess the complexities of the environmental interactions of long-term settlements. Environmental records are assessed using data from 50 sediment profiles, constrained by tephrochronology, located in the farm infields (tún) and outfields (hagi). This record indicates that despite similar outward appearances today, the environs of Dalur and Mörk have experienced different histories of environmental change over the last 1000 years. At least 14 subsidiary settlements were at one time or another established within Dalur, or were dependent on the Church farm there. Ten of these settlements were subsequently abandoned and sediment accumulation rates, a proxy indicator of erosion, remained low, indicating restricted local human impact. We conclude that this illustrates the importance of access and rights to additional resources out with the principal farm. In addition, much of the immediate environs of the main farm site was probably un-wooded at the time of settlement, so the total degree of vegetative change was limited. In contrast, palaeoenvironmental data indicates that the environs of Mörk were extensively wooded at the time of Landnám, but this woodland was rapidly cleared and this was followed by several centuries of landscape instability. In a cultural contrast, the landholdings of Mörk experienced less subdivision with a total of only five dependent farms established across the land belonging to three main farms (all of which had chapels). From the early 10th to 14th centuries there was significantly enhanced erosion within the Mörk landholdings, but this stabilised and the principal farms endured and to form sites of long-term settlement. The ownership of additional resource rights, including woodland further up-valley, may have made the crucial contribution to long term endurance

Charcoal production during the Norse and early medieval periods in Eyjafjallahreppur, Southern Iceland

Timber procurement and the use of woodlands is a key issue in the Norse and Medieval period in the North Atlantic islands. This paper outlines evidence for the timing and mechanisms of Norse deforestation in an area of southern Iceland which is tracked through the mapping and analysis of charcoal production pits. Precise dating of the use of these charcoal production pits within a Bayesian framework is demonstrated through the combination of tephrochronology, sediment accumulation rates and multiple radiocarbon dates on the archaeological charcoal. The implications for using charcoal as a dating medium for radiocarbon dating in Iceland and the wider North Atlantic are then explored. Finally, the nature of the deforestation and human impact on the environment is placed into the context of the Norse landnám across the North Atlantic

An over-optimistic pioneer fringe ? environmental perspectives on medieval settlement abandonment in Þórsmörk, South Iceland.

We assess environmental factors that may have contributed to farm abandonment in Þórsmörk, south Iceland. Here farms were established during the initial Norse colonisation of Iceland and abandoned by the 13th century AD. Soil erosion has been identified as a possible factor in this settlement change. This hypothesis is assessed using sediment profiles constrained by tephrochronology in Þórsmörk and the nearby area of Stakkholt. In Þórsmörk, there is evidence for episodes of landscape instability between the 10th and 13th centuries and localised episodes of soil erosion to bedrock that ended before 1300 AD and the onset of the Little Ice Age (LIA) climate changes. This early instability is absent from Stakkholt. Later LIA stability in Þórsmörk contrasts with episodes of instability in Stakkholt. The implication is that Þórsmörk was sensitive to early settlement impacts that lead to extensive erosion. After farm abandonment in Þórsmörk, the surviving woodland was successfully conserved as a valuable source of wood and charcoal for lowland farms where woodland resources had been depleted. Mounting pressure on woodland resources in the 11th -12th centuries could have been an important factor in determining the precise timing of abandonment

The JCMT Gould Belt Survey: a quantitative comparison between SCUBA-2 data reduction methods

Performing ground-based submillimetre observations is a difficult task as the measurements are subject to absorption and emission from water vapour in the Earth's atmosphere and time variation in weather and instrument stability. Removing these features and other artefacts from the data is a vital process which affects the characteristics of the recovered astronomical structure we seek to study. In this paper, we explore two data reduction methods for data taken with the Submillimetre Common-User Bolometer Array-2 (SCUBA-2) at the James Clerk Maxwell Telescope (JCMT). The JCMT Legacy Reduction 1 (JCMT LR1) and The Gould Belt Legacy Survey Legacy Release 1 (GBS LR1) reduction both use the same software (starlink) but differ in their choice of data reduction parameters. We find that the JCMT LR1 reduction is suitable for determining whether or not compact emission is present in a given region and the GBS LR1 reduction is tuned in a robust way to uncover more extended emission, which better serves more in-depth physical analyses of star-forming regions. Using the GBS LR1 method, we find that compact sources are recovered well, even at a peak brightness of only three times the noise, whereas the reconstruction of larger objects requires much care when drawing boundaries around the expected astronomical signal in the data reduction process. Incorrect boundaries can lead to false structure identification or it can cause structure to be missed. In the JCMT LR1 reduction, the extent of the true structure of objects larger than a point source is never fully recovered

Effective In Vivo Topical Delivery of siRNA and Gene Silencing in Intact Corneal Epithelium Using a Modified Cell-Penetrating Peptide

Autosomal dominantly inherited genetic disorders such as corneal dystrophies are amenable to allele-specific gene silencing with small interfering RNA (siRNA). siRNA delivered to the cornea by injection, although effective, is not suitable for a frequent long-term treatment regimen, whereas topical delivery of siRNA to the cornea is hampered by the eye surface's protective mechanisms. Herein we describe an attractive and innovative alternative for topical application using cell-penetrating peptide derivatives capable of complexing siRNA non-covalently and delivering them into the cornea. Through a rational design approach, we modified derivatives of a cell-penetrating peptide, peptide for ocular delivery (POD), already proved to diffuse into the corneal layers. These POD derivatives were able to form siRNA-peptide complexes (polyplexes) of size and ζ-potential similar to those reported able to undergo cellular internalization. Successful cytoplasmic release and gene silencing in vitro was obtained when an endosomal disruptor, chloroquine, was added. A palmitoylated-POD, displaying the best delivery properties, was covalently functionalized with trifluoromethylquinoline, an analog of chloroquine. This modified POD, named trifluoromethylquinoline-palmitoyl-POD (QN-Palm-POD), when complexed with siRNA and topically applied to the eye in vivo, resulted in up to 30% knockdown of luciferase reporter gene expression in the corneal epithelium. The methods developed within represent a valid standardized approach that is ideal for screening of a range of delivery formulations

Unexpected Consequences: Women’s experiences of a self-hypnosis intervention to help with pain relief during labour.

Background Self-hypnosis is becoming increasingly popular as a means of labour pain management. Previous studies have produced mixed results. There are very few data on women’s views and experiences of using hypnosis in this context. As part of a randomized controlled trial of self-hypnosis for intra-partum pain relief (the SHIP Trial) we conducted qualitative interviews with women randomized to the intervention arm to explore their views and experiences of using self-hypnosis during labour and birth. Methods Participants were randomly selected from the intervention arm of the study, which consisted of two antenatal self-hypnosis training sessions and a supporting CD that women were encouraged to listen to daily from 32 weeks gestation until the birth of their baby. Those who consented were interviewed in their own homes 8-12 weeks after birth. Following transcription, the interviews were analysed iteratively and emerging concepts were discussed amongst the authors to generate organizing themes. These were then used to develop a principal organizing metaphor or global theme, in a process known as thematic networks analysis. Results Of the 343 women in the intervention group, 48 were invited to interview, and 16 were interviewed over a 12 month period from February 2012 to January 2013. Coding of the data and subsequent analysis revealed a global theme of ‘unexpected consequences’, supported by 5 organising themes, ‘calmness in a climate of fear’, ‘from sceptic to believer’, ‘finding my space’, ‘delays and disappointments’ and ‘personal preferences’. Most respondents reported positive experiences of self-hypnosis and highlighted feelings of calmness, confidence and empowerment. They found the intervention to be beneficial and used a range of novel strategies to personalize their self-hypnosis practice. Occasionally women reported feeling frustrated or disappointed when their relaxed state was misinterpreted by midwives on admission or when their labour and birth experiences did not match their expectations. Conclusion The women in this study generally appreciated antenatal self-hypnosis training and found it to be beneficial during labour and birth. The state of focused relaxation experienced by women using the technique needs to be recognized by providers if the intervention is to be implemented into the maternity service

The rate of X-ray-induced DNA double-strand break repair in the embryonic mouse brain is unaff ected by exposure to 50 Hz magnetic fi elds

Following in utero exposure to low dose radiation (10 – 200 mGy), we recently observed a linear induction of DNA double-strand breaks (DSB) and activation of apoptosis in the embryonic neuronal stem/progenitor cell compartment. No signifi cant induction of DSB or apoptosis was observed following exposure to magnetic fi elds (MF). In the present study, we exploited this in vivo system to examine whether exposure to MF before and after exposure to 100 mGy X-rays impacts upon DSB repair rates. Materials and methods : 53BP1 foci were quantifi ed following combined exposure to radiation and MF in the embryonic neuronal stem/progenitor cell compartment. Embryos were exposed in utero to 50 Hz MF at 300 m T for 3 h before and up to 9 h after exposure to 100 mGy X-rays. Controls included embryos exposed to MF or X-rays alone plus sham exposures. Results : Exposure to MF before and after 100 mGy X-rays did not impact upon the rate of DSB repair in the embryonic neuronal stem cell compartment compared to repair rates following radiation exposure alone. Conclusions : We conclude that in this sensitive system MF do not exert any signifi cant level of DNA damage and do not impede the repair of X-ray induced damage

Submillimetre Transient Science in the Next Decade

White paper from the EAO Submillimetre Futures Meeting, 20-23 May 2019, Nanjing, ChinaThis white paper gives a brief summary of the time domain science that has been performed with the JCMT in recent years and highlights the opportunities for continuing work in this field over the next decade. The main focus of this document is the JCMT Transient Survey, a large program initiated in 2015 to measure the frequency and amplitude of variability events associated with protostars in nearby star-forming regions. After summarising the major accomplishments so far, an outline is given for extensions to the current survey, featuring a discussion on what will be possible with the new 850 micron camera that is expected to be installed in late 2022. We also discuss possible applications of submillimetre monitoring to active galactic nuclei, X-ray binaries, asymptotic giant branch stars, and flare stars.Science and Technology Facilities Counci