878 research outputs found
Intra- and interspecific polymorphisms ofLeishmania donovani andL. tropica minicircle DNA
A pair of degenerate polymerase chain reaction (PCR) primers (LEI-1, TCG GAT CC[C,T] [G,C]TG GGT AGG GGC GT; LEI-2, ACG GAT CC[G,C] [G,C][A,C]C TAT [A,T]TT ACA CC) defining a 0.15-kb segment ofLeishmania minicircle DNA was constructed. These primers amplified not only inter- but also intraspecifically polymorphic sequences. Individual sequences revealed a higher intraspecific than interspecific divergence. It is concluded that individual sequences are of limited relevance for species determination. In contrast, when a data base of 19 different sequences was analyzed in a dendrographic plot, an accurate species differentiation was feasible
The Complexity of Repairing, Adjusting, and Aggregating of Extensions in Abstract Argumentation
We study the computational complexity of problems that arise in abstract
argumentation in the context of dynamic argumentation, minimal change, and
aggregation. In particular, we consider the following problems where always an
argumentation framework F and a small positive integer k are given.
- The Repair problem asks whether a given set of arguments can be modified
into an extension by at most k elementary changes (i.e., the extension is of
distance k from the given set).
- The Adjust problem asks whether a given extension can be modified by at
most k elementary changes into an extension that contains a specified argument.
- The Center problem asks whether, given two extensions of distance k,
whether there is a "center" extension that is a distance at most (k-1) from
both given extensions.
We study these problems in the framework of parameterized complexity, and
take the distance k as the parameter. Our results covers several different
semantics, including admissible, complete, preferred, semi-stable and stable
semantics
The heavy quark decomposition of the S-matrix and its relation to the pinch technique
We propose a decomposition of the S-matrix into individually gauge invariant
sub-amplitudes, which are kinematically akin to propagators, vertices, boxes,
etc. This decompsition is obtained by considering limits of the S-matrix when
some or all of the external particles have masses larger than any other
physical scale. We show at the one-loop level that the effective gluon
self-energy so defined is physically equivalent to the corresponding gauge
independent self-energy obtained in the framework of the pinch technique. The
generalization of this procedure to arbitrary gluonic -point functions is
briefly discussed.Comment: 11 uuencoded pages, NYU-TH-94/10/0
Dilution of the magnetic lattice in the Kitaev candidate -RuCl by Rh doping
Magnetic dilution of a well-established Kitaev candidate system is realized
in the substitutional RuRhCl series (). Optimized
syntheses protocols yield uniformly-doped single crystals and polycrystalline
powders that are isostructural to the parental -RuCl as per X-ray
diffraction. The Rh content is accurately determined by the quantitative
energy-dispersive X-ray spectroscopy technique with standards. We determine the
magnetic phase diagram of RuRhCl for in-plane magnetic fields
from magnetization and specific-heat measurements as a function of and
stacking periodicity, and identify the suppression of the magnetic order at towards a disordered phase, which does not show any clear
signature of freezing into a spin glass. Comparing with previous studies on the
substitution series RuIrCl, we propose that chemical pressure
would contribute to the suppression of magnetic order especially in
RuIrCl and that the zigzag magnetic ground state appears to be
relatively robust with respect to the dilution of the
Kitaev----Heisenberg magnetic lattice. We also discovered a slight
dependence of the magnetic properties on thermal cycling, which would be due to
an incomplete structural transition
Compact Labelings For Efficient First-Order Model-Checking
We consider graph properties that can be checked from labels, i.e., bit
sequences, of logarithmic length attached to vertices. We prove that there
exists such a labeling for checking a first-order formula with free set
variables in the graphs of every class that is \emph{nicely locally
cwd-decomposable}. This notion generalizes that of a \emph{nicely locally
tree-decomposable} class. The graphs of such classes can be covered by graphs
of bounded \emph{clique-width} with limited overlaps. We also consider such
labelings for \emph{bounded} first-order formulas on graph classes of
\emph{bounded expansion}. Some of these results are extended to counting
queries
Use of a porous membrane for gas bubble removal in microfluidic channels: physical mechanisms and design criteria
We demonstrate and explain a simple and efficient way to remove gas bubbles
from liquid-filled microchannels, by integrating a hydrophobic porous membrane
on top of the microchannel. A prototype chip is manufactured in hard,
transparent polymer with the ability to completely filter gas plugs out of a
segmented flow at rates up to 7.4 microliter/s per mm2 of membrane area. The
device involves a bubble generation section and a gas removal section. In the
bubble generation section, a T-junction is used to generate a train of gas
plugs into a water stream. These gas plugs are then transported towards the gas
removal section, where they slide along a hydrophobic membrane until complete
removal. The system has been successfully modeled and four necessary operating
criteria have been determined to achieve a complete separation of the gas from
the liquid. The first criterion is that the bubble length needs to be larger
than the channel diameter. The second criterion is that the gas plug should
stay on the membrane for a time sufficient to transport all the gas through the
membrane. The third criterion is that the gas plug travel speed should be lower
than a critical value: otherwise a stable liquid film between the bubble and
the membrane prevents mass transfer. The fourth criterion is that the pressure
difference across the membrane should not be larger than the Laplace pressure
to prevent water from leaking through the membrane
Developmental changes in resting‐state functional networks among individuals with and without internalizing psychopathologies
Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/147755/1/da22864.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/147755/2/da22864_am.pd
Treatment of Branch Retinal Vein Occlusion induced Macular Edema with Bevacizumab
BACKGROUND: Branch retinal vein occlusion is a frequent cause of visual loss with currently insufficient treatment options. We evaluate the effect of Bevacizumab (Avastin) treatment in patients with macular edema induced by branch retinal vein occlusion. METHODS: Retrospective analysis of 32 eyes in 32 patients with fluorescein angiography proven branch retinal vein occlusion, macular edema and Bevacizumab treatment. Outcome measures were best corrected visual acuity in logMAR and central retinal thickness in OCT. RESULTS: Visual acuity was significantly better 4 to 6 weeks after Bevacizumab treatment compared to visual acuity prior to treatment (before 0.7 +/- 0.3 and after 0.5 +/- 0.3; mean +/- standard deviation; p < 0.01, paired t-test). Gain in visual acuity was accompanied by a significant decrease in retinal thickness (454 +/- 117 to 305 +/- 129 microm, p < 0.01, paired t-test). Follow up (170, 27 - 418 days; median, range) shows that improvement for both visual acuity and retinal thickness last for several months after Bevacizumab use. CONCLUSION: We present evidence that intravitreal Bevacizumab is an effective and lasting treatment for macular edema after branch retinal vein occlusion
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