TransNet: A Transfer Learning-Based Network for Human Action Recognition

Human action recognition (HAR) is a high-level and significant research area in computer vision due to its ubiquitous applications. The main limitations of the current HAR models are their complex structures and lengthy training time. In this paper, we propose a simple yet versatile and effective end-to-end deep learning architecture, coined as TransNet, for HAR. TransNet decomposes the complex 3D-CNNs into 2D- and 1D-CNNs, where the 2D- and 1D-CNN components extract spatial features and temporal patterns in videos, respectively. Benefiting from its concise architecture, TransNet is ideally compatible with any pretrained state-of-the-art 2D-CNN models in other fields, being transferred to serve the HAR task. In other words, it naturally leverages the power and success of transfer learning for HAR, bringing huge advantages in terms of efficiency and effectiveness. Extensive experimental results and the comparison with the state-of-the-art models demonstrate the superior performance of the proposed TransNet in HAR in terms of flexibility, model complexity, training speed and classification accuracy

Synthesis, crystal structure and characterization of 3-thiophene aldehyde thiosemicarbazone and its complexes with cobalt(II), nickel(II) and copper(II)

The reaction of cobalt(II), nickel(II), copper(II) chlorides and bromides with 3-thiophene aldehyde thiosemicarbazone (3TTSCH) leads to the formation of a series of new complexes: [Co(3TTSC)2], [Ni(3TTSC)2], [CuCl(3TTSC)]2, [CuBr(3TTSC)]2 and [CuBr2(3TTSCH)]. The crystal structures of the free ligand and of the compound [Ni(3TTSC)2] have been determined by X-ray diffraction methods. For all these complexes, the central ion is coordinated through the sulfur and the azomethine nitrogen atom of the thiosemicarbazone. [Co(3TTSC)2], [Ni(3TTSC)2] and [CuBr2(3TTSCH)] are mononuclear species, while [CuCl(3TTSC)]2 and [CuBr(3TTSC)]2 are binuclear complexes

Reaction of anhydrous zinc chloride with 2,3-thiophenedicarbaldehyde bis(semicarbazone) (2,3BSTCH2) and bis(thiosemicarbazone) (2,3BTSTCH2): Crystal structure of {[C6H5N2S]+[ZnCl3(C6H4N2S)]−} complex

The reaction of anhydrous zinc chloride with 2,3-thiophenedicarbaldehyde bis(semicarbazone) or 2,3-bis(thiosemicarbazone) leads to the formation of compound {[C6H5N2S]+[ZnCl3(C6H4N2S)]−}, where C6H4N2S is thieno[2,3-d]pyridazine, via an elimination-cyclisation reaction of the semicarbazone or the thiosemicarbazone moiety. Crystal structures of thieno[2,3-d]pyridazine and {[C6H5N2S]+[ZnCl3(C6H4N2S)]−} are described. 2015 Institute of Chemistry, Slovak Academy of Science

Synthesis, crystal structure, and characterization of thiophene-3-carboxaldoxime complexes with cobalt(II), nickel(II) and copper(II) halides

The reaction of cobalt(II), nickel(II), copper(II) chlorides and bromides with thiophene-3-carboxaldoxime (3TCOH) leads to a series of new complexes: [CoCl2(3TCOH)4], [CoBr2(3TCOH)4], [NiCl2(3TCOH)4], [NiBr2(3TCOH)4], [CuCl2(3TCOH)4], [CuBr2(3TCOH)2] respectively. The crystal structures of [CoBr2(3TCOH)4], [NiBr2(3TCOH)4] have been determined by X-ray diffraction methods showing octahedral complex species. In all complexes, the oxime functional group remains protonated and the coordination occurs through the nitrogen atom of the oxime moiety

Synthesis, structure and antifungal activity of thiophene-2,3-dicarboxaldehyde bis(thiosemicarbazone) and nickel(II), copper(II) and cadmium(II) complexes: Unsymmetrical coordination mode of nickel complex

AbstractThe reaction of nickel(II), copper(II) chlorides and cadmium(II) chloride and bromide with thiophene-2,3-dicarboxaldehyde bis(thiosemicarbazone) (2,3BTSTCH2) leads to a series of new complexes: [Ni(2,3BTSTCH)]Cl, [Cu(2,3BTSTC)], [CdCl2(2,3BTSTCH2)] and [CdBr2(2,3BTSTCH2)]. The crystal structures of the ligand and of [Ni(2,3BTSTCH)]Cl complex have been determined. In this case, we remark an unusual non-symmetrical coordination mode for the two functional groups: one acting as a thione and the second as a deprotonated thiolate. All compounds have been tested for their antifungal activity against human pathogenic fungi: Candida albicans, Candida glabrata and Aspergillus fumigatus, the cadmium complexes exhibit the highest antifungal activity. Cytotoxicity was evaluated using two biological methods: human MRC5 cultured cells and brine shrimp Artemia salina bioassay

Synthesis, crystal structure, characterization of zinc(II), cadmium(II) complexes with 3-thiophene aldehyde thiosemicarbazone (3TTSCH). Biological activities of 3TTSCH and its complexes

The reaction of zinc(II) chloride, cadmium(II) chloride and bromide with 3-thiophene aldehyde thiosemicarbazone leads to the formation of a series of new complexes. They have been characterized by spectroscopic studies: infrared, 1H NMR, and electronic spectra. The crystal structures of the compound [ZnCl2(3TTSCH)2] and [CdBr2(3TTSCH)2] have been determined by X-ray diffraction methods. For the complexes [ZnCl2(3TTSCH)2] and [CdBr2(3TTSCH)2], the central ion is coordinated through the sulfur, and for the complexes [CdCl2(3TTSCH)], [CdBr2(3TTSCH)] the ion is coordinated through the sulfur as well as azomethine nitrogen atom of the thiosemicarbazone. In addition, fungistatic and bacteriostatic activities of both ligand and complexes have been evaluated. Cadmium(II) complexes have shown the most significant activities

A Link Between Methylglyoxal and Heart Failure During HIV-1 Infection

Early-onset heart failure (HF) continues to be a major cause of morbidity and mortality in people living with human immunodeficiency virus type one (HIV-1) infection (PLWH), yet the molecular causes for this remain poorly understood. Herein NOD.Cg- PrkdcscidIl2rgtm1Wjl/SzJ humanized mice (Hu-mice), plasma from PLWH, and autopsied cardiac tissues from deceased HIV seropositive individuals were used to assess if there is a link between the glycolysis byproduct methylglyoxal (MG) and HF in the setting of HIV-1 infection. At five weeks post HIV infection, Hu-mice developed grade III-IV diastolic dysfunction (DD) with an associated two-fold increase in plasma MG. At sixteen-seventeen weeks post infection, cardiac ejection fraction and fractional shortening also declined by 26 and 35%, and plasma MG increased to four-fold higher than uninfected controls. Histopathological and biochemical analyses of cardiac tissues from Hu-mice 17 weeks post-infection affirmed MG increase with a concomitant decrease in expression of the MG-degrading enzyme glyoxalase-1 (Glo1). The endothelial cell marker CD31 was found to be lower, and coronary microvascular leakage and myocardial fibrosis were prominent. Increasing expression of Glo1 in Hu-mice five weeks post-infection using a single dose of an engineered AAV2/9 (1.7 × 1012 virion particles/kg), attenuated the increases in plasma and cardiac MG levels. Increasing Glo1 also blunted microvascular leakage, fibrosis, and HF seen at sixteen weeks post-infection, without changes in plasma viral loads. In plasma fromvirally suppressed PLWH,MG was also 3.7-fold higher. In autopsied cardiac tissues from seropositive, HIV individuals with low viral log, MG was 4.2-fold higher and Glo1 was 50% lower compared to uninfected controls. These data show for the first time a causal link between accumulation of MG and HF in the setting of HIV infection

EXPERIMENTAL EVIDENCE OF PHYSIOLOGICAL AND BEHAVIORAL EFFECTS OF MICROPLASTICS INGESTION IN SPARUS AURATA

Increasing global research has identified microplastics (MPs) to be impacting marine organisms. The present work aimed at investigating the physiological and behavioral effects of thirty-six juvenile Sparus aurata exposed to control, virgin and weathered MPs enriched diets during a 21-day period under controlled conditions. Physiological effects were assessed in liver and brain using the following biomarkers: activities of the antioxidant enzymes catalase (CAT), superoxide dismutase (SOD), glutathione peroxidase (GPx) and glutathione reductase (GRd), the detoxifying enzyme glutathione S-transferase (GST) and malondialdehyde (MDA) as indicative of lipid peroxidation. Individuals were recorded for behavior analysis (i.e. social interactions and feeding behavior). Results revealed an increase in cellular stress from control to weathered fish groups, with the virgin group showing intermediate levels in all quantified biomarkers. Significant differences were found in the liver for all biomarkers except for MDA, suggesting that exposure time to MPs in this experiment is long enough to trigger the activation of antioxidant enzymes but not to produce cell damage by lipid peroxidation. In brain tissue samples, fish from the weathered group presented significantly higher values for CAT and SOD, highlighting its function as primary antioxidants. Regarding behavioral effects, results showed that the two MPs enriched groups were significantly bolder during social interactions and, although no significantly, tended to be more active during feeding. In conclusion, MPs which have been weathered in marine environmental conditions produces a higher physiological response than virgin MPs but also, a physiological response is variable depending on the tissue analyzed. In addition, a short period to MP exposure seems to affect overall social and feeding behavior but, further research is needed to assess long-term effects of MP ingestion and its potential consequences on fish populations