915 research outputs found
Building CMS Pixel Barrel Detectur Modules
For the barrel part of the CMS pixel tracker about 800 silicon pixel detector
modules are required. The modules are bump bonded, assembled and tested at the
Paul Scherrer Institute. This article describes the experience acquired during
the assembly of the first ~200 modules.Comment: 5 pages, 7 figures, Vertex200
CMS Barrel Pixel Detector Overview
The pixel detector is the innermost tracking device of the CMS experiment at
the LHC. It is built from two independent sub devices, the pixel barrel and the
end disks. The barrel consists of three concentric layers around the beam pipe
with mean radii of 4.4, 7.3 and 10.2 cm. There are two end disks on each side
of the interaction point at 34.5 cm and 46.5 cm. This article gives an overview
of the pixel barrel detector, its mechanical support structure, electronics
components, services and its expected performance.Comment: Proceedings of Vertex06, 15th International Workshop on Vertex
Detector
Symmetry implies independence
Given a quantum system consisting of many parts, we show that symmetry of the
system's state, i.e., invariance under swappings of the subsystems, implies
that almost all of its parts are virtually identical and independent of each
other. This result generalises de Finetti's classical representation theorem
for infinitely exchangeable sequences of random variables as well as its
quantum-mechanical analogue. It has applications in various areas of physics as
well as information theory and cryptography. For example, in experimental
physics, one typically collects data by running a certain experiment many
times, assuming that the individual runs are mutually independent. Our result
can be used to justify this assumption.Comment: LaTeX, contains 4 figure
Tight Finite-Key Analysis for Quantum Cryptography
Despite enormous progress both in theoretical and experimental quantum
cryptography, the security of most current implementations of quantum key
distribution is still not established rigorously. One of the main problems is
that the security of the final key is highly dependent on the number, M, of
signals exchanged between the legitimate parties. While, in any practical
implementation, M is limited by the available resources, existing security
proofs are often only valid asymptotically for unrealistically large values of
M. Here, we demonstrate that this gap between theory and practice can be
overcome using a recently developed proof technique based on the uncertainty
relation for smooth entropies. Specifically, we consider a family of
Bennett-Brassard 1984 quantum key distribution protocols and show that security
against general attacks can be guaranteed already for moderate values of M.Comment: 11 pages, 2 figure
Magnetic circular dichroism of x-ray absorption spectroscopy at rare-earth L2,3 edges in RE2Fe14B compounds (RE = La, Pr, Nd, Sm, Gd, Tb, Dy, Ho, Er, Tm, Yb, and Lu)
Magnetic circular dichroism (MCD) in the x-ray absorption spectroscopy (XAS)
at the L2,3 edges for almost entire series of rare-earth (RE) elements in
RE2Fe14B, is studied experimentally and theoretically. By a quantitative
comparison of the complicated MCD spectral shapes, we find that (i) the 4f-5d
intra-atomic exchange interaction not only induces the spin and orbital
polarization of the 5d states, which is vital for the MCD spectra of the
electric dipole transition from the 2p core states to the empty 5d conduction
band, but also it accompanies a contraction of the radial part of the 5d wave
function depending on its spin and orbital state, which results in the
enhancement of the 2p-5d dipole matrix element, (ii) there are cases where the
spin polarization of the 5d states due to the hybridization with the spin
polarized 3d states of surrounding irons plays important roles, and (iii) the
electric quadrupole transition from the 2p core states to the magnetic vale!
nce 4f states is appreciable at the pre-edge region of the dipole spectrum.
Especially, our results evidence that it is important to include the
enhancement effect of the dipole matrix element in the correct interpretation
of the MCD spectra at the RE L2,3 edges.Comment: 9 pages, 5 figures, 1 table, REVTe
Potentially inappropriate medication in older participants of the Berlin Aging Study II (BASE-II) - Sex differences and associations with morbidity and medication use
INTRODUCTION:
Multimorbidity in advanced age and the need for drug treatment may lead to polypharmacy, while pharmacokinetic and pharmacodynamic changes may increase the risk of adverse drug events (ADEs).
OBJECTIVE:
The aim of this study was to determine the proportion of subjects using potentially inappropriate medication (PIM) in a cohort of older and predominantly healthy adults in relation to polypharmacy and morbidity.
METHODS:
Cross-sectional data were available from 1,382 study participants (median age 69 years, IQR 67-71, 51.3% females) of the Berlin Aging Study II (BASE-II). PIM was classified according to the EU(7)-PIM and German PRISCUS (representing a subset of the former) list. Polypharmacy was defined as the concomitant use of at least five drugs. A morbidity index (MI) largely based on the Charlson Index was applied to evaluate the morbidity burden.
RESULTS:
Overall, 24.1% of the participants were affected by polypharmacy. On average, men used 2 (IQR 1-4) and women 3 drugs (IQR 1-5). According to PRISCUS and EU(7)-PIM, 5.9% and 22.6% of participants received at least one PIM, while use was significantly more prevalent in females (25.5%) compared to males (19.6%) considering EU(7)-PIM (p = 0.01). In addition, morbidity in males receiving PIM according to EU(7)-PIM was higher (median MI 1, IQR 1-3) compared to males without PIM use (median MI 1, IQR 0-2, p<0.001).
CONCLUSION:
PIM use occurred more frequently in women than in men, while it was associated with higher morbidity in males. As expected, EU(7)-PIM identifies more subjects as PIM users than the PRISCUS list but further studies are needed to investigate the differential impact of both lists on ADEs and outcome.
KEY POINTS:
We found PIM use to be associated with a higher number of regular medications and with increased morbidity. Additionally, we detected a higher prevalence of PIM use in females compared to males, suggesting that women and people needing intensive drug treatment are patient groups, who are particularly affected by PIM use
Generation of Continuous Variable Einstein-Podolsky-Rosen Entanglement via the Kerr Nonlinearity in an Optical Fibre
We report on the generation of a continuous variable Einstein-Podolsky-Rosen
(EPR) entanglement using an optical fibre interferometer. The Kerr nonlinearity
in the fibre is exploited for the generation of two independent squeezed beams.
These interfere at a beam splitter and EPR entanglement is obtained between the
output beams. The correlation of the amplitude (phase) quadratures are measured
to be 4.0+-0.2 (4.0+-0.4) dB below the quantum noise limit. The sum criterion
for these squeezing variances 0.80+-0.03 < 2 verifies the nonseparability of
the state. The product of the inferred uncertainties for one beam 0.64+-0.08 is
well below the EPR limit of unity.Comment: RevTeX, 4 pages, 3 figures, to be published in Phys. Rev. Let
The Uncertainty Principle in the Presence of Quantum Memory
The uncertainty principle, originally formulated by Heisenberg, dramatically
illustrates the difference between classical and quantum mechanics. The
principle bounds the uncertainties about the outcomes of two incompatible
measurements, such as position and momentum, on a particle. It implies that one
cannot predict the outcomes for both possible choices of measurement to
arbitrary precision, even if information about the preparation of the particle
is available in a classical memory. However, if the particle is prepared
entangled with a quantum memory, a device which is likely to soon be available,
it is possible to predict the outcomes for both measurement choices precisely.
In this work we strengthen the uncertainty principle to incorporate this case,
providing a lower bound on the uncertainties which depends on the amount of
entanglement between the particle and the quantum memory. We detail the
application of our result to witnessing entanglement and to quantum key
distribution.Comment: 5 pages plus 12 of supplementary information. Updated to match the
journal versio
Microscopic Study of Superdeformed Rotational Bands in 151Tb
Structure of eight superdeformed bands in the nucleus 151Tb is analyzed using
the results of the Hartree-Fock and Woods-Saxon cranking approaches. It is
demonstrated that far going similarities between the two approaches exist and
predictions related to the structure of rotational bands calculated within the
two models are nearly parallel. An interpretation scenario for the structure of
the superdeformed bands is presented and predictions related to the exit spins
are made. Small but systematic discrepancies between experiment and theory,
analyzed in terms of the dynamical moments, J(2), are shown to exist. The
pairing correlations taken into account by using the particle-number-projection
technique are shown to increase the disagreement. Sources of these systematic
discrepancies are discussed -- they are most likely related to the yet not
optimal parametrization of the nuclear interactions used.Comment: 32 RevTeX pages, 15 figures included, submitted to Physical Review
The epidemiology of pertussis in Germany: past and present
<p>Abstract</p> <p>Background</p> <p>Current and past pertussis epidemiology in the two parts of Germany is compared in the context of different histories of vaccination recommendations and coverage to better understand patterns of disease transmission.</p> <p>Methods</p> <p>Available regional pertussis surveillance and vaccination coverage data, supplemented by a literature search for published surveys as well as official national hospital and mortality statistics, were analyzed in the context of respective vaccination recommendations from 1964 onwards.</p> <p>Results</p> <p>Routine childhood pertussis vaccination was recommended in the German Democratic Republic (GDR) from 1964 and in former West German states (FWG) from 1969, but withdrawn from 1974–1991 in FWG. Pertussis incidence declined to <1 case/100.000 inhabitants in GDR prior to reunification in 1991, while in FWG, where pertussis was not notifiable after 1961, incidence was estimated at 160–180 cases/100.000 inhabitants in the 1970s-1980s. Despite recommendations for universal childhood immunization in 1991, vaccination coverage decreased in former East German States (FEG) and increased only slowly in FWG. After introduction of acellular pertussis vaccines in 1995, vaccination coverage increased markedly among younger children, but remains low in adolescents, especially in FWG, despite introduction of a booster vaccination for 9–17 year olds in 2000. Reported pertussis incidence increased in FEG to 39.3 cases/100.000 inhabitants in 2007, with the proportion of adults increasing from 20% in 1995 to 68% in 2007. From 2004–2007, incidence was highest among 5–14 year-old children, with a high proportion fully vaccinated according to official recommendations, which did not include a preschool booster until 2006. Hospital discharge statistics revealed a ~2-fold higher pertussis morbidity among infants in FWG than FEG.</p> <p>Conclusion</p> <p>The shift in pertussis morbidity to older age groups observed in FEG is similar to reports from other countries with longstanding vaccination programs and suggests that additional booster vaccination may be necessary beyond adolescence. The high proportion of fully vaccinated cases in older children in FEG suggests waning immunity 5–10 years after primary immunisation in infancy. The higher incidence of pertussis hospitalisations in infants suggests a stronger force of infection in FWG than FEG. Nationwide pertussis reporting is required for better evaluation of transmission patterns and vaccination policy in both parts of Germany.</p
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