Effect of Impeller Inlet Geometry on Cavitation Performance of Centrifugal Pumps Based on Radial Basis Function

Aiming at the cavitation problem, the blade leading edge shape has been changed to analyze its impact on the cavitation performance for centrifugal pumps. And the response model has been established based on the Radial Basis Function. The calculation case results show that the leading edge extending forward along the shroud can improve the inlet flow condition and cavitation performance. But the cavitation performance has been reduced immensely when the leading edge extends backward along the shroud. Along with the leading edge which extends forward along the hub, the cavitation performance increases at first and then decreases. A better cavitation performance for centrifugal pumps has lower load of blade inlet and higher pressure of blade suction side. The pressure pulsation is affected by the vortex out of the impeller and the falling-off and collapsing of the cavitation bubbles. The lower the pressure pulsation for blade passing frequency and the second harmonics of the samples is, the better the cavitation performance is. A relatively accurate response model based on the Radial Basis Function has been established to predict the effect of the shape of blade leading edge on the cavitation performance of centrifugal pumps

FERM domain-containing unconventional myosin VIIA interacts with integrin β5 subunit and regulates αvβ5-mediated cell adhesion and migration

AbstractUnconventional myosin VIIA (Myo7a) has been known to associate with hereditary deafness. Here we present a novel function of Myo7a by identifying that Myo7a directly interacts with integrin β5 subunit and regulates cell adhesion and motility in an integrin-dependent manner. We found that Myo7a bound to the cytoplasmic tail of integrin β5. Further, we pinpointed an integrin-binding domain at F3 of the first FERM domain and F1 of the second FERM domain. Functionally, Myo7a-induced cell adhesion and migration were mediated by integrin αvβ5. These findings indicated that Myo7a interacts with integrin β5 and selectively promotes integrin αvβ5-mediated cell migration

Visual Clustering of Spam Emails for DDoS Analysis

Networking attacks embedded in spam emails are increasingly becoming numerous and sophisticated in nature. Hence this has given a growing need for spam email analysis to identify these attacks. The use of these intrusion detection systems has given rise to other two issues, 1) the presentation and understanding of large amounts of spam emails, 2) the user-assisted input and quantified adjustment during the analysis process. In this paper we introduce a new analytical model that uses two coefficient vectors: 'density' and 'weight'for the analysis of spam email viruses and attacks. We then use a visual clustering method to classify and display the spam emails. The visualization allows users to interactively select and scale down the scope of views for better understanding of different types of the spam email attacks. The experiment shows that this new model with the clustering visualization can be effectively used for network security analysis

Synergistic Reducing Effect for Synthesis of Well-Defined Au Nanooctopods With Ultra-Narrow Plasmon Band Width and High Photothermal Conversion Efficiency

Branched Au nanoparticles have attracted intense interest owing to their remarkable properties and a wide variety of potential applications in surface-enhanced Raman spectroscopy (SERS), photothermal therapy, photoacoustic imaging, and biomedicines. The morphology and spatial arrangement of branches play the most crucial role in the determination of their properties and applications. However, it is still a synthetic challenge to control the exact arm numbers of branches with specific spatial arrangements. Here we report a facile method for the kinetically controlled growth of Au nanooctopods (NOPs) with a high yield (81%), monodispersity, and reproducibility by using the synergistic reducing effect of ascorbic acid and 1-methylpyrrolidine. The NOPs have eight arms elongated along <111> directions with uniform arm lengths. Due to their well-defined size and shape, NOPs show ultra-narrow surface plasmon band width with a full width at half maximum of only 76 nm (0.20 eV). Upon irradiation with laser, the NOPs possessed excellent photothermal conversion efficiencies up to 83.0% and photoacoustic imaging properties. This work highlights the future prospects of using NOPs with desired physicochemical properties for biomedical applications

Boosting biomethane yield and production rate with graphene: the potential of direct interspecies electron transfer in anaerobic digestion

Interspecies electron transfer between bacteria and archaea plays a vital role in enhancing energy efficiency of anaerobic digestion (AD). Conductive carbon materials (i.e. graphene nanomaterial and activated charcoal) were assessed to enhance AD of ethanol (a key intermediate product after acidogenesis of algae). The addition of graphene (1.0 g/L) resulted in the highest biomethane yield (695.0 ± 9.1 mL/g) and production rate (95.7 ± 7.6 mL/g/d), corresponding to an enhancement of 25.0% in biomethane yield and 19.5% in production rate. The ethanol degradation constant was accordingly improved by 29.1% in the presence of graphene. Microbial analyses revealed that electrogenic bacteria of Geobacter and Pseudomonas along with archaea Methanobacterium and Methanospirillum might participate in direct interspecies electron transfer (DIET). Theoretical calculations provided evidence that graphene-based DIET can sustained a much higher electron transfer flux than conventional hydrogen transfer

Synthesis and Properties of Ni-doped Goethite and Ni-doped Hematite Nanorods

Ni-doped goethite (α-FeOOH) nanorods were synthesized from mixed Fe(III)-Ni(II) nitrate solutions with various Ni/(Ni+Fe) ratios (0, 5, 10, 20, 33 and 50 mol % Ni) by hydrothermal precipitation in a highly alkaline medium using the strong organic alkali, tetramethylammonium hydroxide (TMAH). Ni-doped hematite (α-Fe2O3) nanorods were obtained by calcination of Ni-doped goethite nanorods at 400 °C. The Ni 2+ -for-Fe 3+ substitution in goethite and hematite was confirmed by determination of the unit cell expansion (due to the difference in the ionic radii of Fe 3+ and Ni 2+ ) using XRPD and determination of the reduction of a hyperfine magnetic field (due to the difference in magnetic moments of Fe 3+ and Ni 2+ ) using Mössbauer spectroscopy. Single-phase goethite nanorods were found in samples containing 0 or 5 mol % Ni. A higher Ni content in the precipitation system (10 mol % or more) resulted in a higher Ni 2+ -for-Fe 3+ substitution in goethite, and larger Ni-doped goethite nanorods, though with the presence of low crystalline Ni-containing ferrihydrite and Ni ferrite (NiFe2O4) as additional phases. Significant changes in FT-IR and UV-Vis-NIR spectra of prepared samples were observed with increasing Ni content. Electrochemical measurements of samples showed a strong increase in oxygen evolution reaction (OER) electrocatalytic activity with increasing Ni content. © 2018 Croatian Chemical Society. All Rights Reserved

Cross-satellite calibration of high-energy electron fluxes measured by FengYun-4A based on Arase observations

We use the High-energy Electron Experiments (HEP) instrument onboard Arase (ERG) to conduct an energy-dependent cross-satellite calibration of electron fluxes measured by the High Energy Particle Detector (HEPD) onboard FengYun-4A (FY-4A) spanning from April 1, 2017, to September 30, 2019. By tracing the two-dimensional magnetic positions (L, magnetic local time [MLT]) of FY-4A at each time, we compare the datasets of the conjugate electron fluxes over the range of 245–894 keV in 6 energy channels for the satellite pair within different sets of L × MLT. The variations in the electron fluxes observed by FY-4A generally agree with the Arase measurements, and the percentages of the ratios of electron flux conjunctions within a factor of 2 are larger than 50%. Compared with Arase, FY-4A systematically overestimates electron fluxes at all 6 energy channels, with the corresponding calibration factors ranging from 0.67 to 0.81. After the cross-satellite calibration, the electron flux conjunctions between FY-4A and Arase show better agreement, with much smaller normalized root mean square errors. Our results provide a valuable reference for the application of FY-4A high-energy electron datasets to in-depth investigations of the Earth’s radiation belt electron dynamics

High prevalence of Rickettsia spp. in ticks from wild hedgehogs rather than domestic bovine in Jiangsu province, Eastern China

BackgroundSpotted fever group Rickettsia (SFGR), containing various pathogenic Rickettsia spp., poses remarkable negative influences to public health by causing various severe or mild diseases. Information regarding prevalence of SFGR in ticks in Jiangsu province, Eastern China, is still limited and needs urgent investigations.MethodsHedgehog- and bovine-attached ticks were collected from Jiangsu province, Eastern China. DNA of individual ticks was extracted for nested polymerase chain reaction amplifications targeting gltA, 16S ribosomal RNA (rrs), ompA, ompB, and sca4 genes following with sequencing. SFGR-specific IgG antibodies in sera of local donators were evaluated using ELISA.ResultsOverall, 144 (83.2%) of the 173 ticks from hedgehogs and 2 (1.2%) of the 168 ticks from bovine were positive for one of the three identified Rickettsia spp., with significant difference between the two groups (P = 3.6e-52). Candidatus Rickettsia principis (9; 5.2%) and R. heilongjiangensis (135; 78.0%) were detected in Haemaphysalis flava rather than in H. longicornis ticks from hedgehogs. R. heilongjiangensis (1; 0.6%) and Candidatus R. jingxinensis (or Candidatus R. longicornii) (1; 0.6%) were identified in H. longicornis and Rhipicephalus microplus ticks from bovine, respectively. Phylogenetic analysis indicated Candidatus R. jingxinensis belonged to R. japonica subgroup, whereas Candidatus R. principis belonged to a novel subgroup. Higher serological prevalence of spotted fever and SFGR-specific IgG antibody level in humans were observed around the investigated area than in urban areas, without significant difference.ConclusionCandidatus R. principis and Candidatus R. jingxinensis were identified in Jiangsu province, Eastern China, and fully genetically characterized for the first time. The higher prevalence of SFGR in hedgehog-attached ticks as well as the higher SFGR-specific IgG antibody level and seropositive rate in humans around the investigated area suggested that more attention should be paid to SFGR. This pathogen is usually transmitted or harbored by wild animals and ticks. This study provides important epidemiological data for both physicians and public health officers in developing early prevention and control strategies against potential Rickettsia infections and in the preparation of suitable testing and treatment needs for rickettsiosis in the endemic areas