Pd nanoparticles confined in mesoporous N-doped carbon silica supports: a synergistic effect between catalyst and support

Palladium nanoparticles of similar size were deposited on different supports, layers of carbon materials (with and without nitrogen doping) on the surface of a MCF (mesocellular foam) silica. For the generation of the N-doped carbon coatings, three different N sources were used to also investigate a possible influence of the N-doped carbon precursor and thus the structure of the N-doped carbons on their performance as catalyst support. These catalysts were tested for the Suzuki coupling and hydrogenation reactions. For the Suzuki reaction, the carbon coatings showed to increase dramatically the stability of the MCF material. Furthermore, when N-doped carbon coatings were applied, strong improvement of the stability of the catalysts was observed due to an enhanced interaction between metal nanoparticles and the support, preventing metal particle growth. In hydrogenation reactions, the presence of the N-doped carbon coating on the silica support increases the adsorption of aromatic compounds causing an enhancement of the catalytic activity of Pd NPs when compared to the non-doped supports.TU Berlin, Open-Access-Mittel - 2020DFG, 390540038, EXC 2008: UniSysCa

Evaluation of Intraoperative Volumetric Assessment of Breast Volume Using 3D Handheld Stereo Photogrammetric Device.

Methods for assessing three-dimensional (3D) breast volume are becoming increasingly popular in breast surgery. However, the precision of intraoperative volumetric assessment is still unclear. Until now, only non-validated scanning systems have been used for intraoperative volumetric analyses. This study aimed to assess the feasibility, handling, and accuracy of a commercially available, validated, and portable device for intraoperative 3D volumetric evaluation. All patients who underwent breast surgery from 2020 to 2022 were identified from our institutional database. Intraoperative 3D volumetric assessments of 103 patients were included in this study. Standardized 3D volumetric measurements were obtained 3 months postoperatively to compare the intraoperatively generated volumetric assessment. All of the study participants were women with a mean age of 48.3 ± 14.7 years (range: 20-89). The mean time for intraoperative volumetric assessment was 8.7 ± 2.6 min. The postoperative 3D volumetric assessment, with a mean volume of 507.11 ± 206.29 cc, showed no significant difference from the intraoperative volumetric measurements of 504.24 ± 276.61 cc (p = 0.68). The mean absolute volume difference between the intraoperative simulations and postoperative results was 27.1 cc. Intraoperative 3D volumetric assessment using the VECTRA H2 imaging system seems to be a feasible, reliable, and accurate method for measuring breast volume. Based on this finding, we plan to investigate whether volumetric objective evaluations will help to improve breast symmetry in the future

Early Response Assessment after Intraarterial Therapy Using 3D Quantitative Tumor Enhancement Analysis

PURPOSE Liver metastases from renal cell carcinoma (RCC) are not uncommon in the course of disease. However, data about tumor response to intraarterial therapy (IAT) are scarce. This study assessed whether changes of enhancing tumor volume using quantitative European Association for the Study of the Liver (qEASL) on magnetic resonance imaging (MRI) and computed tomography (CT) can evaluate tumor response and predict overall survival (OS) early after therapy. METHODS AND MATERIALS Fourteen patients with liver metastatic RCC treated with IAT (transarterial chemoembolization: n= 9 and yttrium-90: n= 5) were retrospectively included. All patients underwent contrast-enhanced imaging (MRI: n= 10 and CT: n= 4) 3 to 4 weeks pre- and posttreatment. Response to treatment was evaluated on the arterial phase using Response Evaluation Criteria in Solid Tumors (RECIST), World Health Organization, modified RECIST, EASL, tumor volume, and qEASL. Paired t test was used to compare measurements pre- and post-IAT. Patients were stratified into responders (≥65% decrease in qEASL) and nonresponders (<65% decrease in qEASL). OS was evaluated using Kaplan-Meier curves with log-rank test and the Cox proportional hazard model. RESULTS Mean qEASL (cm3) decreased from 93.5 to 67.2 cm3 (P= .004) and mean qEASL (%) from 63.1% to 35.6% (P= .001). No significant changes were observed using other response criteria. qEASL was the only significant predictor of OS when used to stratify patients into responders and nonresponders with median OS of 31.9 versus 11.1 months (hazard ratio [HR], 0.43; 95% confidence interval [CI], 0.19-0.97; P= .042) for qEASL (cm3) and 29.9 versus 10.2 months (HR, 0.09; 95% CI, 0.01-0.74; P= .025) for qEASL (%). CONCLUSION Three-dimensional (3D) quantitative tumor analysis is a reliable predictor of OS when assessing treatment response after IAT in patients with RCC metastatic to the liver. qEASL outperforms conventional non- 3D methods and can be used as a surrogate marker for OS early after therapy

Renal Cell Carcinoma Metastatic to the Liver: Early Response Assessment after Intraarterial Therapy Using 3D Quantitative Tumor Enhancement Analysis

AbstractPURPOSELiver metastases from renal cell carcinoma (RCC) are not uncommon in the course of disease. However, data about tumor response to intraarterial therapy (IAT) are scarce. This study assessed whether changes of enhancing tumor volume using quantitative European Association for the Study of the Liver (qEASL) on magnetic resonance imaging (MRI) and computed tomography (CT) can evaluate tumor response and predict overall survival (OS) early after therapy.METHODS AND MATERIALSFourteen patients with liver metastatic RCC treated with IAT (transarterial chemoembolization: n= 9 and yttrium-90: n= 5) were retrospectively included. All patients underwent contrast-enhanced imaging (MRI: n= 10 and CT: n= 4) 3 to 4 weeks pre- and posttreatment. Response to treatment was evaluated on the arterial phase using Response Evaluation Criteria in Solid Tumors (RECIST), World Health Organization, modified RECIST, EASL, tumor volume, and qEASL. Paired t test was used to compare measurements pre- and post-IAT. Patients were stratified into responders (≥65% decrease in qEASL) and nonresponders (<65% decrease in qEASL). OS was evaluated using Kaplan-Meier curves with log-rank test and the Cox proportional hazard model.RESULTSMean qEASL (cm3) decreased from 93.5 to 67.2 cm3 (P= .004) and mean qEASL (%) from 63.1% to 35.6% (P= .001). No significant changes were observed using other response criteria. qEASL was the only significant predictor of OS when used to stratify patients into responders and nonresponders with median OS of 31.9 versus 11.1 months (hazard ratio [HR], 0.43; 95% confidence interval [CI], 0.19-0.97; P= .042) for qEASL (cm3) and 29.9 versus 10.2 months (HR, 0.09; 95% CI, 0.01-0.74; P= .025) for qEASL (%).CONCLUSIONThree-dimensional (3D) quantitative tumor analysis is a reliable predictor of OS when assessing treatment response after IAT in patients with RCC metastatic to the liver. qEASL outperforms conventional non-3D methods and can be used as a surrogate marker for OS early after therapy

Complex electrophysiological remodeling in postinfarction ischemic heart failure

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Tratamento de alveolite e retalho periodontal rotacionado

Introdução: As alveolites são problemas que se iniciam durante o pós-operatório, caracterizadas pela presença de dor e desconforto no local de realização do procedimento cirúrgico, podendo ser causada por iatrogenias, má higienização e a não colaboração do paciente com as recomendações pós-cirúrgicas, as principais formas de tratamento estão relacionadas a utilização de técnicas como a relatada no caso em questão e a prescrição medicamentosa adequada por parte do cirurgião-dentista. Objetivo: Abordar um relato de caso demonstrando uma forma de tratamento para alveolite utilizando recomposição periodontal. Metodologia: Tratasse de um relato de caso utilizando uma abordagem qualitativa da literatura associada aos exames de imagem, anamnese minuciosa e fotografias odontológica. Relato de Caso: O paciente E.S.M, 26 anos de idade, negro, portador de vitiligo, apresentou-se a clínica escola Ana Lúcia Chaves Fecury, com queixa de que após a exodontia começou a sentir dor e desconforto local na região do dente extraído de número há 07 dias, como forma de tratamento para essa intercorrência fora indicado a recomposição periodontal e prescrição de e antibióticos. Conclusão: Cabe ao cirurgião-dentista elaborar estratégias que visem restabelecer a saúde do paciente, objetivando elaborar um planejamento de forma cautelosa para os tratamentos de alveolite sec

Study on Green Energy Converter for the Purpose of Optimising Teaching and Learning in Energy Science

Knowledge of energy conservation is vital to be understood by students in grasping the topic of energy science. Hence, a study has been piloted to produce energy converter which can be used practically by the students to understand about the conversion of energy from kinetic energy to electricity. In the convertible of kinetic energy to electrical energy, as these energy undergo conversion, the kinetic energy are stored in two forms of storage apparatus. The first type is synchronous flywheels which operate within the allowable range of the synchronous frequency. The second type is asynchronous flywheels whose rotational speed is independent from the system synchronous frequency and varied over a wide range and this features gives the asynchronous flywheel the ability to store and release significant amount of kinetic energy. The outcomes from this study displayed successful performance which is dynamo that act as generator for the converter as energy is being convert from the kinetic energy into the electrical energy and efficaciously can be used to charge electrical gadget

Psychometric properties of the Alcohol Use Disorders Identification Test (AUDIT) across cross-cultural subgroups, genders, and sexual orientations: Findings from the International Sex Survey (ISS)

© 2023 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/bync-nd/4.0/).INTRODUCTION: Despite being a widely used screening questionnaire, there is no consensus on the most appropriate measurement model for the Alcohol Use Disorders Identification Test (AUDIT). Furthermore, there have been limited studies on its measurement invariance across cross-cultural subgroups, genders, and sexual orientations. AIMS: The present study aimed to examine the fit of different measurement models for the AUDIT and its measurement invariance across a wide range of subgroups by country, language, gender, and sexual orientation. METHODS: Responses concerning past-year alcohol use from the participants of the cross-sectional International Sex Survey were considered (N = 62,943; M age: 32.73; SD = 12.59). Confirmatory factor analysis, as well as measurement invariance tests were performed for 21 countries, 14 languages, three genders, and four sexual-orientation subgroups that met the minimum sample size requirement for inclusion in these analyses. RESULTS: A two-factor model with factors describing 'alcohol use' (items 1-3) and 'alcohol problems' (items 4-10) showed the best model fit across countries, languages, genders, and sexual orientations. For the former two, scalar and latent mean levels of invariance were reached considering different criteria. For gender and sexual orientation, a latent mean level of invariance was reached. CONCLUSIONS: In line with the two-factor model, the calculation of separate alcohol-use and alcohol-problem scores is recommended when using the AUDIT. The high levels of measurement invariance achieved for the AUDIT support its use in cross-cultural research, capable also of meaningful comparisons among genders and sexual orientations.Peer reviewe