Efektivitas Kinerja Staf Administrasi Bidang Kemahasiswaan

The purpose of this study was to determine objectively about the effectiveness of the performance of the administrative staff were seen monitoring and performance measurement. This study uses a qualitative approach to case study type. The data sources are: Chairman of the school of theology as a key informant who supported other sources. While collecting the data collection techniques, through interviews, observation, and documentation. The technique of data analysis through the model of Miles and Huberman. Based on research, it can be concluded that: (1) The increase in administrative staff performance through the implementation of monitoring and measurement of performance. (2) While the measurement of performance through measurement to communicate aspects of work, and taking the measurements to communicate aspects of the work, and aspects of measurement to define priorities for action; (3) Beside all that aspects, to increase the administrative staff performance through work standard, actual performance, based on policy, usefull of performance, problem and solution of performance, and the effort to increase administrative staff performance

ANALISIS KESALAHAN SISWA DALAM MENYELESAIKAN SOAL PERSAMAAN EKSPONEN

Jenis penelitian ini adalah kualitatif deskriptif yang bertujuan untuk mengetahui jenis-jenis kesalahan yang dilakukan oleh siswa dalam menyelesaikan soal persamaan eksponen. Penelitian ini dilakukan dikelas X SMA Xaverius Ambon tahun ajaran 2022/2023 pada bulan juli sampai bulan agustus 2022. Teknik pengumpulan data yang digunakan adalah teknik tes dan wawancara. Instrumen penelitian yaitu lembar tes dan pedoman wawancara. Data hasil tes dianalisis agar dapat mengetahui jenis-jenis kesalahan dan juga sebagai dasar pemilihan subjek wawancara yaitu tiga orang siawa. Data hasil wawancara digunakan sebagai pembanding data hasil tes. Analisis data diambil melalui langkah-langkah reduksi data, penyajian data, dan penarikan kesimpulan. Kesimpulan yang diperoleh yaitu kesalahan yang dilakukan siswa dalam menyelesaikan soal persamaan eksponen, dilihat dari objek matematika yaitu kesalahan fakta, kesalahan konsep, kesalahan prinsip, dan kesalahan operas

Economic Analysis Of An Integrated Annatto Seeds-sugarcane Biorefinery Using Supercritical Co2 Extraction As A First Step

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Recently, supercritical fluid extraction (SFE) has been indicated to be utilized as part of a biorefinery, rather than as a stand-alone technology, since besides extracting added value compounds selectively it has been shown to have a positive effect on the downstream processing of biomass. To this extent, this work evaluates economically the encouraging experimental results regarding the use of SFE during annatto seeds valorization. Additionally, other features were discussed such as the benefits of enhancing the bioactive compounds concentration through physical processes and of integrating the proposed annatto seeds biorefinery to a hypothetical sugarcane biorefinery, which produces its essential inputs, e.g., CO2, ethanol, heat and electricity. For this, first, different configurations were modeled and simulated using the commercial simulator Aspen Plus (R) to determine the mass and energy balances. Next, each configuration was economically assessed using MATLAB. SFE proved to be decisive to the economic feasibility of the proposed annatto seeds-sugarcane biorefinery concept. SFE pretreatment associated with sequential fine particles separation process enabled higher bixin-rich extract production using low-pressure solvent extraction method employing ethanol, meanwhile tocotrienols-rich extract is obtained as a first product. Nevertheless, the economic evaluation showed that increasing tocotrienols-rich extract production has a more pronounced positive impact on the economic viability of the concept.96FAPESP [2013/18114-2, 2015/06954-1, 2012/10685-8, 2015/13299-0]CAPES [7545-15-0]CNPq [301301/2010-7]Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq

Bioclimatic buildings strategies for the climate of Araras city, São Paulo - Brazil

The concept of bioclimatic architecture or passive solar architecture can be defined as an architecture that includes the climate as an important variable in the design process. Through the use of bioclimatic strategies the environment comfort can be obtained naturally for users of buildings, which depending on the climate, the construction techniques and the type of use. Considering these aspects, the main objective of this work is to identify bioclimatic strategies for buildings for the climate of Araras city, countryside of São Paulo State - Brazil, based on climatic characterization of the city and in the study of design guidelines indicated by the Brazilian Code NBR 15220-3, the Brazilian Bioclimatic Zoning. According to the code, the climate of Araras is inserted in Bioclimatic Zone 4. For this climate the main indicated strategies for winter are the use of solar passive heating and massive internal walls in buildings. For summer, the use of evaporative cooling and ventilation are indicated. Based on this information were established initial guidelines for thermal comfort and energy efficiency for projects of buildings in the climate of Araras-SP

Quantification of alpha-amanitin in biological samples by HPLC using simultaneous UV- diode array and electrochemical detection

α-Amanitin is a natural bicyclic octapeptide, from the family of amatoxins, present in the deadly mushroom species Amanita phalloides. The toxicological and clinical interests raised by this toxin, require highly sensitive, accurate and reproducible quantification methods for pharmacokinetic studies. In the present work, a high-performance liquid chromatographic (HPLC) method with in-line connected diode-array (DAD) and electrochemical (EC) detection was developed and validated to quantify α-amanitin in biological samples (namely liver and kidney). Sample pre-treatment consisted of a simple and unique deproteinization step with 5% perchloric acid followed by centrifuga tion at 16,000. ×g, 4. °C, for 20. min. The high recovery found for α-amanitin (≥96.8%) makes this procedure suitable for extracting α-amanitin from liver and kidney homogenates. The resulting supernatant was collected and injected into the HPLC. Mobile phase was composed by 20% methanol in 50. mM citric acid, and 0.46. mM octanessulfonic acid, adjusted to pH 5.5. The chromatographic runs took less than 22. min and no significant endogenous interferences were observed at the α-amanitin retention time. Calibration curves were linear with regression coefficients higher than 0.994. The overall inter- and intra-assay precision did not exceed 15.3%.The present method has low interferences with simple and fast processing steps, being a suitable procedure to support in vivo toxicokinetic studies involving α-amanitin. In fact, the validated method was successfully applied to quantify α-amanitin in biological samples following intraperitoneal α-amanitin administration to rats. Moreover, human plasma was also used as matrix and the purposed method was adequate for detection of α-amanitin in that matrix. The results clearly indicate that the proposed method is suitable to investigate the pharmacokinetic and tissue distribution of α-amanitin. Additionally, the method will be very useful in the development of novel and potent antidotes against amatoxins poisoning and to improve the knowledge of α-amanitin toxicity.This work received financial support from the European Union (FEDER funds through COMPETE) and National Funds (FCT, Fundação para a Ciência e Tecnologia) through project Pest- C/EQB/LA0006/2013. Juliana Garcia and Vera Marisa Costa thank FCT - Foundation for Science and Technology - for their PhD grant (SFRH/BD/74979/ 2010 ) and Post-doc grant (SFRH/BPD/63746/2009), respectively.info:eu-repo/semantics/publishedVersio

Modified electrodes prepared with polyphenolic film containing ruthenium complex and metal ligand anchored by azo covalent bond

This work presents two new modified carbon electrodes which were prepared via the polymerization of a phenolic moiety previously functionalized with azo groups (bipyridine and 2-methoxypyridine) as key structures to anchor the desired ligands. The syntheses of BAP (4-([2,2’]-bipyridinyl-4-ylazo)-phenol) and PAPmethoxy (5-(4-hidroxyphenylazo) pyridin-2-methoxy) were simple to perform, gave good yields and the monomers were easily electropolymerized resulting in chemically and mechanically stable modified electrodes. The PAP-methoxy ME formed stable complexes with Cd, Cu and Pb in aqueous media at open circuit and produced well defined redox peaks, showing good potential for future analytical applications. The BAP monomer was used to produce a ruthenium complex (BAP-Ru) which was electropolymerized from +0.50 to +0.75V (vs. Ag/AgCl) to leave the ruthenium available to act as a catalyst. The BAP-Ru ME was able to oxidize a variety of organic substrates with good selectivity. The yields obtained were either similar to, or better than, those obtained by homogeneous catalysis using a similar ruthenium catalyst or when this type of catalyst is supported in a carbon paste electrode.Este trabalho apresenta dois novos eletrodos de grafite modificados que foram preparados via polimerização da função fenólica, previamente funcionalizada por grupos azo (bipiridina e 2-metoxipiridina), que atuam como estruturas chaves para a ancoragem de ligantes de interesse. As sínteses dos monômeros BAP (4-([2,2’]bipiridinil-4-ilazo)-fenol) e PAPmetóxi (5-(4-hidroxifenilazo)piridin-2-metóxi) foram simples, deram bons rendimentos e os monômeros foram facilmente eletropolimerizados, levando à formação de eletrodos modificados (EM) química e mecanicamente estáveis. Em solução aquosa e em circuito aberto, o EM PAP-metóxi formou complexos estáveis com Cd, Cu e Pb, produzindo picos redox bem definidos, demonstrando o grande potencial deste eletrodo para futuras aplicações analíticas. O monômero BAP foi utilizado para produzir um complexo de rutênio (BAP-Ru) que foi eletropolimerizado entre +0.50 e +0.75V (vs. Ag/AgCl), permitindo que o rutênio permanecesse disponível para atuar como catalisador. O EM BAP-Ru oxidou seletivamente uma variedade de substratos orgânicos dando produtos com rendimentos próximos ou melhores que aqueles obtidos por catálise homogênea com complexos de rutênio similares, ou quando este tipo de catalisador é impregnado em pasta de carbono.CNPqCoordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES

Descoloration of industrial dyes and simulated textile effluents dyes by turnip peroxidase

The removal of important textile dyes by turnip peroxidase (TNP) was evaluated. The textile effluents besides the residual dyes contain also chemical auxiliaries such as salts, dispersing and wetting agents. The effect of these was evaluated in the removal of the dyes reactive blue 21 and reactive blue 19 by TNP in synthetic effluents. A decrease of the efficency decolorization was observed. The action of the enzyme on colour removal of dye mixture was equivalent to the dyes alone. The chemical demand of oxygen in the effluent after enzymatic treatment had a significant increase in relation to the untreated effluent

Comparative antioxidant and antimicrobial properties of Lentinula edodes Donko and Koshin varieties against priority multidrug-resistant pathogens

The problematic increase in multidrug-resistant bacteria translates into the urgent need to discover novel and effective antimicrobial substances. Herein, mushrooms could be a promising alternative of natural source of new antimicrobials. The present work aimed to compare the phytochemical composition and antimicrobial activity of methanol and aqueous crude extracts of Lentinula edodes var. Koshin and Donko. Disk diffusion method was used to screen the antimicrobial activity and to assess the synergistic effect of the mushroom extracts. Microdilution method was used to determine the minimum inhibitory concentration (MIC) and the minimum bactericidal concentration (MBC). Phytochemical characterization of mushrooms extracts was achieved by analysis of total phenols, ortho-diphenols content and its antioxidant activity. The results noticed a positive relation between phenolic compounds content, antioxidant activity, and antimicrobial capacity of the mushroom's extracts. The L. edodes var. Koshin aqueous extracts, which contained the highest amount of total phenolic compounds, exhibited the highest scavenging capacity of ABTS which, in turns, exhibited the highest antimicrobial efficacy in inhibiting the growth of methicillin-resistant Staphylococcus aureus. Moreover, the combination between mushrooms extracts and commercial antibiotics showed favorable synergistic effects against tested bacteria. These results suggest that L. edodes var. Koshin may represent an important and valuable therapeutic source of compounds to be used against multidrug-resistant bacteria.This work was supported by the project I&T Companies in Co- Promotion FungiTech, Norte-01-0247-FEDER-033788; National Funds by FCT - Portuguese Foundation for Science and Technology, under the project UIDB/04033/2020 (CITAB-Center for the Research and Technology of Agro-Environmental and Biological Sciences), Centro de Química – Vila Real (UIDB/00616/2020) and UIDB/00690/2020 (CIMO-Centro de Investigaç˜ao de Montanha).info:eu-repo/semantics/publishedVersio