Faktor risiko konstipasi pada anak

ABSTRACT Dyah Kurniati, M. Juffrie\u27 - Risk factors of constipation in children Background: Despite it is not considered as a dangerous situation in children older than 2 years old, but attention is important in young infant. Improper treatment in constipation may contributed to the raise of anxiety, emotionally disorder either for the children or its relatives. Objective: To determine risk factors related to constipation in children. Design and Methods: A case control study was conducted for all of children who were admitted to ambulatory polyclinic and inpatient clinic of Sardjito Hospital during January 2001 - December 2001. A questionnaire was obtained by the researcher or assistant by direct interview to parent or guardian. Results: We enrolled 86 children, consisted of 43 children in constipation group and the 43 children as control. There was significant difference (p < 0.01) between two groups in the presence of the symptoms (abdominal pain, pain during defecation, vomit, decrease of appetite and encopresis). More children in constipation group and significant difference (

Faktor Risiko Konstipasi Pada Anak

Dyah Kurniati, M. Juffrie - Risk factors of childhood constipation Background: Despite it is not considered as a dangerous situation in children older than 2 years old, but attantion is important in young infant. Improper treatment in constipation may contributed to the raise of anxiety, emotionally disorder either for the children or its relatives. Objective: To determine what factors related to constipation in children. Design and Methods: A case control study was conducted for all of children who were admitted to ambulatory polyclinic and inpatient clinic of Sardjito Hospital during January 2001 - December 2001. A questionaire was obtained by the researcher or assistant by direct interview to the parents or guardian. Results: We enrolled 86 children, consisted of 43 children in constipation group and the 43 children as control. There was significant difference (

Penambahan agar-agar dan pengaruhnya terhadap kestabilan dan daya terima susu tempe pada mahasiswa Politeknik Kesehatan Jurusan Gizi Yogyakarta

Background: The production of tempeh milk is an effort to diversify tempeh-based food processing potential as functional food. However, as vegetable milk tempeh milk has the disadvantages of tasting bitter and being easily precipitate. The addition of gelatine is potential as stabilizer that is expected to counter the disadvantages and improve the taste of tempeh milk. Objective: To identify the effect of gelatine addition to stability and acceptability of tempeh milk among students of Nutrition Department of Health Polytechnic Yogyakarta. Method: The study was experimental with a completely randomized design, comprising four experiments, i.e. tempeh milk with gelatine addition as much as 2%, 3%, 4% and no gelatine addition as control. Organoleptic test was made by 25 skilled panelist, students of Nutrition Department of Health Polytechnic Yogyakarta, to identify acceptability of tempeh milk. Whereas viscocity test and visual observation through the assessment of tempeh milk precipitation level within 5 hours storage were made to identify emulsion stability. Data analysis used Anova and Duncan advanced test. Result: Stable emulsion could be achieved through gelatine addition of 2% at emulsion consistency 89.10%, viscocity 0.225 poise. Better emulsion stability was achieved through gelatine addition of 3% at emulsion consistency 91.10%, viscocity 0.249 poise. Best emulsion stability was achieved through gelatine addition of 4% at emulsion consistency 95.58%, viscocity 0.254 poise and lowest emulsion stability was found in the control without gelatine addition at emulsion consistency 80.84%, viscocity 0.216 poise. The result of proximate nutrition value of tempeh milk with gelatine addition 4% (most stable) were energy 55.54 cal, protein 2.14gr, fat 1.82g, carbohydrate 7.65%, water 86.23g, ash 0.15% and raw fibre 2.01%. Conclusion: There was no effect of gelatine addition at various concentration to acceptability of tempeh milk. There was effect of gelatine addition at various concentration to stability of tempeh milk. The highest emulsion stability was achieved in tempeh milk with gelatine addition of 4%

Faktor risiko kejadian stunting pada anak umur 6-36 bulan di Wilayah Pedalaman Kecamatan Silat Hulu, Kapuas Hulu, Kalimantan Barat

ABSTRACTBackground: Stunting in children under five is an indicator of nutritional status that can reflect problem of overall social economic condition in the past. Stunting that occurs in childhood is a risk factor of increasing in mortality rate, low cognitive capability and motoric development, and improper physical function. The incidence of stunting is associated with many factors such as family environment (education, occupation, income, rearing pattern, eating pattern, and number of family members), nutritional factors (exclusivebreastfeeding and duration of breastfeeding), genetic factor, infection disease, and the incidence of low birth weight. The scope of stunting in 2010 were 35,6% and 39,7% in Indonesia and Province of Kalimantan Barat.Objectives: To identify the risk factors associated with the incidence of stunting in children of 6-36 months in Silat Hulu District of Kapuas Hulu, Province of Kalimantan Barat.Methods: This was an analytic observational study with cross sectional design. Population of the study were all of underfi ves children at remote area of Subdistrict of Silat Hulu, District of Kapuas Hulu, Province of Kalimantan Barat. Data analysis used chi-square test and logistic regression analysis to identify themost dominantly determinant stunting variable.Results: The incidence of stunting was significantly associated with occupation of mother, height of father, height of mother, income, number of family members, rearing pattern, and exclusive breastfeeding supplementation (p&lt;0.05). The incidence of stunting was not associated with occupation of father, eating pattern, duration of breastfeeding, infection disease, and education of mother (p&gt;0.05).Conclusions: Factors associated with the incidence of stunting were the work of mothers, rearing pattern, family income, number of household members, father’s height, maternal height, and exclusive breastfeeding. The most dominant determinant of risk factors on the incidence of stunting were exclusivebreastfeeding, number of household members, maternal height, income, and father’s height.KEYWORDS: exclusive breastfeeding, height of father, height of mother, income, stuntingABSTRAKLatar belakang: Stunting pada anak balita merupakan indikator status gizi yang dapat memberikan gambaran gangguan keadaan sosial ekonomi secara keseluruhan di masa lampau. Stunting yang terjadi pada masa anak merupakan faktor risiko meningkatnya angka kematian, kemampuan kognitif dan perkembangan motorik yang rendah, dan fungsi tubuh yang tidak seimbang. Kejadian stunting berhubungan dengan berbagai macam faktor antara lain lingkungan keluarga (pendidikan, pekerjaan, pendapatan, pola asuh, pola makan dan jumlah anggota rumah tangga), faktor gizi (ASI eksklusif danlama pemberian ASI), faktor genetik, penyakit infeksi, dan kejadian BBLR. Menurut hasil riset kesehatan dasar, prevalensi anak balita yang menderita stunting di Indonesia pada tahun 2010 masih tinggi sebesar 35,6%, dan 39,7% di Provinsi Kalimantan Barat.Tujuan: Mengetahui faktor risiko yang berhubungan dengan kejadian stunting pada anak umur 6-36 bulan di pedalaman Kecamatan Silat Hulu, Kabupaten Kapuas Hulu, Provinsi Kalimantan Barat.Metode: Penelitian ini merupakan penelitian observasional analitik dengan rancangan cross sectional. Populasinya adalah seluruh balita yang ada di wilayah pedalaman Kecamatan Silat Hulu Kabupaten Kapuas Hulu Provinsi Kalimantan Barat. Analisis data menggunakan uji chi-square dan untuk mengetahui variabel paling determinan terhadap stunting dilakukan analisis regresi logistik.Hasil: Kejadian stunting berhubungan signifi kan dengan pekerjaan ibu, tinggi badan ayah, tinggi badan ibu, pendapatan, jumlah anggota rumah tangga, pola asuh, dan pemberian ASI eksklusif (p&lt;0,05). Kejadian stunting tidak berhubungan dengan, pekerjaan ayah, pola makan, lama pemberian ASI, penyakit infeksi, dan pendidikan ibu (p&gt;0,05).Kesimpulan: Faktor yang berhubungan dengan kejadian stunting adalah pekerjaan ibu, pola asuh, pendapatan keluarga, jumlah anggota rumah tangga, tinggi badan ayah, tinggi badan ibu, dan pemberian ASI eksklusif. Faktor risiko determinan terhadap kejadian stunting adalah pendapatan, jumlah anggotarumah tangga, tinggi badan ayah, tinggi badan ibu, dan pemberian ASI eksklusif.KATA KUNCI: stunting, pendapatan, jumlah anggota rumah tangga, tinggi badan, ayah, tinggi badan ibu, pemberian ASI eksklusi

Hubungan Antara Kadar Serum Albumin Awal dengan Lama Rawat Inap Dan Status Pulang Pasien Dewasa Di rumah sakit

Background: Several community studies have reported a relationship between a low serum albumin level and increased risk of hospital death, nosocomial infection, and length of stay. But this kind of study is still lacking in Indonesia. Objective: To assess the relationship between admission serum albumin levels with length of stay and recovery rate among adult hospitalized patients. Method: This cohort study was done in 2002. Subjects of this study were adults, inpatient of internal and neurological departments of Dr.Sardjito, Dr. M. Jamil and Sanglah hospitals. Serum albumin level, total lymphocyte count (TLC), and hemoglobin from each subject were collected at the admission. Energy intake of each subject was obtained using visual Comstock method. Information of length of stay and recovery status at discharge was obtained from medical records. Result: On average the length of stay (LOS) in patients with normal serum albumin was 9.8 days. In patients with low serum albumin the LOS was 2 days longer (

Faktor risiko gizi buruk pada balita di Kabupaten Donggala Provinsi Sulawesi Tengah

ABSTRACTBackground: Severe malnutrition is a state of severe malnourished condition caused by low consumption of energy and protein in a long time. Severe malnutrition interferes the children growth and development, moreover malnourished children are vulnerable to get infectious diseases, even the death.Objectives: To analyze the risk factors of severe malnutrition among children under five in Donggala, Central of Sulawesi Province.Methods: This study used case-control (observational study). The study was conducted in District Dampelas Donggala on July to September 2014. The population was all children underfive selected by total sampling method. The samples were 64 children aged 0-59 months which separated into 2 groups,case and control group.The independent variables were the level of energy intake of protein, parenting, and infectious diseases, while the dependent variable was the incidence of severe malnutrition among children under five. Data were obtained by direct interview using questionnaire and recall 24 hours to determine the level of energy and protein intake. The data collected were analyzed using univariate analysis (descriptive), bivariate (chi-square), and multivariate (multiple logistic regression).Results: The result of this study based on the bivariate analysis presented that the level of energy intake (OR=9.86, 95% CI:3.49-27.89), infectious disease (OR=2.83, 95% CI:1.10-7.31), and as low birth weight external variables (OR=5.76, 95% CI:1.43-23.20) signifi cantly associated with the incidence of severe malnutrition. There were no significant association between the level of protein intake (OR=1.18, 95% CI:0.47-2.92) and parenting (OR=1.21, 95% CI:0.50-2.92) with the incidence of severe malnutrition. In the other hand, based on multivariate analysis by controlling the variable of low birth weight history, this study’s result presented that the level of energy intake had the strongest association with the risk of incidence of severe malnutrition compared to the other variables.Conclusions: The level of energy intake and infectious disease were the risk factors for the incidence of severe malnutrition among children under five, while the level of protein intake and parenting were not.KEYWORDS: children underfive, energy, infectious disease, parenting, protein, severe malnutritionABSTRAKLatar belakang: Gizi buruk adalah keadaan kurang gizi tingkat berat yang disebabkan oleh rendahnya konsumsi energi dan protein dalam waktu cukup lama. Kekurangan gizi selain mengganggu pertumbuhan dan perkembangan, dapat pula mengakibatkan balita rentan terhadap penyakit infeksi bahkan dapatmenyebabkan kematian.Tujuan: Untuk menganalisis faktor risiko kejadian gizi buruk pada balita di Kabupaten Donggala, Provinsi Sulawesi Tengah.Metode: Jenis penelitian ini observasional dengan rancangan case-control. Penelitian dilakukan di Kecamatan Dampelas, Kabupaten Donggala pada bulan Juli sampai September 2014. Populasi adalah semua balita dan sampel ditentukan dengan metode total sampling. Balita usia 0–59 bulan yang berjumlah 64 dimasukkan pada masing-masing kelompok kasus dan kontrol. Variabel bebas yaitu tingkat asupan energi protein, pola asuh, dan penyakit infeksi sedangkan variabel terikatnya adalah kejadian gizi buruk pada balita. Data diperoleh dengan wawancara langsung menggunakan kuesioner dan recall 24 jam untuk mengetahui tingkat asupan energi dan protein. Data dianalisis dengan analisis univariat (deskriptif), bivariat (chi-square), dan multivariat (regresi logistik berganda).Hasil: Hasil analisis bivariat menunjukkan bahwa tingkat asupan energi (OR=9,86, 95% CI:3,49-27,89), penyakit infeksi (OR=2,83, 95% CI:1,10-7,31), dan variabel luar BBLR (OR=5,76, 95% CI:1,43-23,20) berhubungan signifikan dengan gizi buruk. Tidak ada hubungan yang signifikan antara tingkat asupan protein (OR=1,18, 95%CI:0,47-2,92) dan pola asuh (OR=1,21, 95%CI:0,50-2,92) dengan gizi buruk. Hasil analisis multivariat dengan mengendalikan riwayat BBLR menunjukkan bahwa tingkat asupan energi memiliki hubungan kuat dengan risiko kejadian gizi buruk dibandingkan variabel lainnya.Kesimpulan: Tingkat asupan energi dan penyakit infeksi merupakan faktor risiko kejadian gizi buruk padabalita, sedangkan tingkat asupan protein dan pola asuh bukan merupakan faktor risiko.KATA KUNCI: balita, energi, penyakit infeksi, pola asuh, protein, gizi buruk, giz

Pengaruh Asap Rokok Terhadap Kualitas Hidup Total Penderita Rinitis Alergi Persisten

Introduction: The effect of cigarette smoke on Persistent Allergic Rhinitis patients (RAP) prevalence is increasing in Indonesia. Although the number of people who smoke is increasing yet it has not received attention for examination. Objective: To analyze the relationship between cigarette smoking "side-stream" (SS) with the change in total quality of life (TQL) among patients with Persistent Allergic Rhinitis (PAR). Method: This study is a case-control design, in which 63 patients with moderate-severe RAP evidenced by allergy tests are divided into treatment groups (32) and control (31) randomly. RAP 32 patients were exposed to cigarette smoke (SS) from 5 cigarettes for 2 hours in a room. All respondents were asked to fill out questionnaires quality of life of Juniper's RQLQ. Results: KH total between treatment groups was not significantly different with control. KH total exposed to secondhand smoke every day significantly different. Discussion: Cigarette smoke described in patients with RAP does not lead to changes in the quality of life

Gene Expression Profiling during Early Acute Febrile Stage of Dengue Infection Can Predict the Disease Outcome

Background: We report the detailed development of biomarkers to predict the clinical outcome under dengue infection. Transcriptional signatures from purified peripheral blood mononuclear cells were derived from whole-genome gene-expression microarray data, validated by quantitative PCR and tested in independent samples. Methodology/Principal Findings: The study was performed on patients of a well-characterized dengue cohort from Recife, Brazil. The samples analyzed were collected prospectively from acute febrile dengue patients who evolved with different degrees of disease severity: classic dengue fever or dengue hemorrhagic fever (DHF) samples were compared with similar samples from other non-dengue febrile illnesses. The DHF samples were collected 2-3 days before the presentation of the plasma leakage symptoms. Differentially-expressed genes were selected by univariate statistical tests as well as multivariate classification techniques. The results showed that at early stages of dengue infection, the genes involved in effector mechanisms of innate immune response presented a weaker activation on patients who later developed hemorrhagic fever, whereas the genes involved in apoptosis were expressed in higher levels. Conclusions/Significance: Some of the gene expression signatures displayed estimated accuracy rates of more than 95%, indicating that expression profiling with these signatures may provide a useful means of DHF prognosis at early stages of infection. © 2009 Nascimento et al

Role of the Chemokine Receptors CCR1, CCR2 and CCR4 in the Pathogenesis of Experimental Dengue Infection in Mice

Dengue virus (DENV), a mosquito-borne flavivirus, is a public health problem in many tropical countries. Recent clinical data have shown an association between levels of different chemokines in plasma and severity of dengue. We evaluated the role of CC chemokine receptors CCR1, CCR2 and CCR4 in an experimental model of DENV-2 infection in mice. Infection of mice induced evident clinical disease and tissue damage, including thrombocytopenia, hemoconcentration, lymphopenia, increased levels of transaminases and pro-inflammatory cytokines, and lethality in WT mice. Importantly, infected WT mice presented increased levels of chemokines CCL2/JE, CCL3/MIP-1α and CCL5/RANTES in spleen and liver. CCR1-/- mice had a mild phenotype with disease presentation and lethality similar to those of WT mice. In CCR2-/- mice, lethality, liver damage, levels of IL-6 and IFN-γ, and leukocyte activation were attenuated. However, thrombocytopenia, hemoconcentration and systemic TNF-α levels were similar to infected WT mice. Infection enhanced levels of CCL17/TARC, a CCR4 ligand. In CCR4-/- mice, lethality, tissue injury and systemic inflammation were markedly decreased. Despite differences in disease presentation in CCR-deficient mice, there was no significant difference in viral load. In conclusion, activation of chemokine receptors has discrete roles in the pathogenesis of dengue infection. These studies suggest that the chemokine storm that follows severe primary dengue infection associates mostly to development of disease rather than protection