148 research outputs found

    The Effects of Parental Incarceration on the School Behavior of Poor Urban Black Children

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    Children whose parents are incarcerated experience emotional traumas that are harmful to their social competence and overall well-being. When parents go to prison, children’s lives become traumatic, distressed, and unstable. Young children who are unable to articulate their emotional distress instead manifest disruptive behaviors in school. Poor black children who display disruptive behaviors in school are at especially high-risk for exclusionary discipline practices, such as suspension and expulsion. These practices have been shown to negatively impact the development of their social and emotional competence and further impede their academic achievement. The HOPE Project was a 3-year pilot project that provided school-based therapeutic services to black children with incarcerated parents. The children were enrolled in three elementary schools located in an urban, poverty-impacted community. Program evaluation findings suggest that intense age-appropriate therapy conducted in schools is a helpful intervention for reducing negative in-school behaviors and increasing the social and emotional competence of poor, urban black children to keep them engaged in school. The findings have important implications for social work practice in the school setting with children who have parents that are incarcerated

    Maize (Zea mays L) cultivars nutrients concentration in leaves and stalks

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    There is pressure for crop residue removal for use as biofuel, animal feed, animal bedding and many other func¬tions which may increase nutrient export. However, there is little information about nutritional composition of maize stover considering the wide variability of cultivars used. The aim of this study was to evaluate the influence of maize cultivar on macronutrient (P, K, Ca, and Mg), micronutrient (Fe, Mn, Zn, and Cu) and Na concentration in leaves and stalks. We selected five pairs of cultivars, ranging from creole to high potential hybrid (creole, commer¬cial variety, single, double and triple cross hybrid). The cultivars were cropped under field conditions in high fertile Rhodic Ferralsol Eutric during two growing seasons. The first was characterized by severe drought (2005/2006) while the second with an abundant water supply (2006/2007). The leaf and stalk concentrations of P, K, Ca, Mg, Fe, Mn, Na, Zn, Cu, and C/P ratio were quantified at maturation stage. The results indicated that the P concen¬tration in leaves and stalks was inversely related to the technological level when simple hybrid was compared to creole cultivars. Similar behavior was observed for K in the leaf and stalk tissues. For Ca, Mg, Fe, Mn, Zn, Cu, and Na, it was not possible to establish the influence of maize selection. The C/P ratio of leaves and stalks underwent influence of the technological level with high values for simple hybrids. Maize selection seems to decrease P and K concentration for two major residue fractions, leaves and stalks

    Processing GPS Occultation Data To Characterize Atmosphere

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    GOAS [Global Positioning System (GPS) Occultation Analysis System] is a computer program that accepts signal-occultation data from GPS receivers aboard low-Earth-orbiting satellites and processes the data to characterize the terrestrial atmosphere and, in somewhat less comprehensive fashion, the ionosphere. GOAS is very robust and can be run in an unattended semi-operational processing mode. It features sophisticated retrieval algorithms that utilize the amplitudes and phases of the GPS signals. It incorporates a module that, using an assumed atmospheric refractivity profile, simulates the effects of the retrieval processing system, including the GPS receiver. GOAS utilizes the GIPSY software for precise determination of orbits as needed for calibration. The GOAS output for the Earth s troposphere and mid-to-lower stratosphere consists of high-resolution (<1 km) profiles of density, temperature, pressure, atmospheric refractivity, bending angles of signals, and water-vapor content versus altitude from the Earth s surface to an altitude of 30 km. The GOAS output for the ionosphere consists of electron-density profiles from an altitude of about 50 km to the altitude of a satellite, plus parameters related to the rapidly varying structure of the electron density, particularly in the E layer of the ionosphere

    Parallel CRISPR-Cas9 screens clarify impacts of p53 on screen performance

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    CRISPR-Cas9 genome engineering has revolutionised high-throughput functional genomic screens. However, recent work has raised concerns regarding the performance of CRISPR-Cas9 screens using TP53 wild-type human cells due to a p53-mediated DNA damage response (DDR) limiting the efficiency of generating viable edited cells. To directly assess the impact of cellular p53 status on CRISPR-Cas9 screen performance, we carried out parallel CRISPR-Cas9 screens in wild-type and TP53 knockout human retinal pigment epithelial cells using a focused dual guide RNA library targeting 852 DDR-associated genes. Our work demonstrates that although functional p53 status negatively affects identification of significantly depleted genes, optimal screen design can nevertheless enable robust screen performance. Through analysis of our own and published screen data, we highlight key factors for successful screens in both wild-type and p53-deficient cells
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