509 research outputs found

    La calidad de vida y el estrés

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    Se profundiza sobre los conceptos de calidad de vida y estrés con el propósito de brindar al lector un mayor conocimiento de éstos y, de esta forma, conservar o mejorar la calidad de vida y reducir los efectos negativos del estrés.ITESO, A.C

    Autoproblem : motor generador de problemes d'estadistica bàsica

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    Els objectius del projecte són: -Crear un conjunt d'aplicacions portables a qualsevol ordinador, per tal de que arribi al màxim d'usuaris possibles sigui quina sigui la seva situació geografica, si és a casa o si és a la facultat. D'aquesta manera es vol crear una aplicació que es pogués utilitiar com a material de classes de pràctiques, o com a material d'examen, o simplement perque l'estudiant pugui estudiar l'assignatura. - Creació d'un conjunt de rutines de simulació de dades aleatóries. D'aquesta manera estudiants que executen el mateix problema alhora tenen dades diferents, i per tant poden arribar a conclusions diferents. - La creació d'un programa d'edició de problemes senzill i fàcíl d'utilitzar per part del professor. - Crear una aplicació de resolució seqüencial i guiada deis problemes plantejats pel professor. Aquest és un dels objectius més importants, doncs es vol que l'estudiant resolgui el problema plantejat per l'aplicació de manera que posi en pràctica tot el que ha après a la classe i a més, que el resolgui d'una manera seqüencial. La creació d'un sistema de control deis estudiants que executin els problemes a la pàgina web. Aquest objectiu assolir aquest objectiu és important de cara a fer pràctiques o exàmens amb l'aplicació de l'estudiant. D'aquesta manera el professor pot conèixer l'evolució deIs seus estudiants al llarg del quadrimestres en que es faci l'assígnatura

    Microencapsulation of ellagic acid from pomegranate husk and karaya gum by spray drying

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    Objective: The aim of this study was to obtain and characterize microcapsules with Ellagic Acid (EA) from pomegranate as core material and Karaya Gum (KG) as wall material. Methods: EA was obtained from dry pomegranate peel powder via methanolysis and quantified by HPLC. Microcapsules were obtained preparing a dispersion containing KG and EA in phosphate buffer pH 8. The dispersion was processed in a spray dryer under specific conditions (inlet temperature at 150 °C, feed flow at 30% and aspirator at 100 %) for obtaining of microcapsules. Fourier transform infrared (FTIR) spectroscopy, differential scanning calorimetry (DSC) and scanning electron microscopy (SEM) were used for characterization. Results: Obtained material contains 98.03±2.82 mg EA/g of pomegranate peel. FTIR showed that there were changes in the molecular structure of microcapsules referred to raw materials. SEM confirmed that particles obtained had micron-size (1-5 µm). DSC analysis showed that raw materials had glass transition temperatures of 79.58 and 83.41 °C and for microcapsules the value was67.25 °C. Conclusion: Methanolysis is a viable technique for the obtaining of EA from the peel of pomegranate. KG shows good potential for be used as wall material for EA microencapsulation

    Red Nacional de Estaciones de Referencia GPS (ERGPS)

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    El Instituto Geográfico Nacional, por medio del Área de Geodesia, está llevando a cabo el establecimiento de una Red de Estaciones Permanentes GPS que permitan obtener coordenadas muy precisas, así como sus campos de velocidades en un Sistema de Referencia Global (ITRFxx). Dichas estaciones pertenecen a la Red de Estaciones Permanentes de EUREF (EUropean REference Frame) y constituyen el orden cero de la Geodesia Española

    Red GPS Fiduciaria Nacional de España

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    El Instituto Geográfico Nacional, por medio del Área de Geodesia, está llevando a cabo el establecimiento de una Red de Estaciones Permanentes GPS que permitan obtener coordenadas muy precisas, así como sus campos de velocidades en un Sistema de Referencia Global (ITRFxx). Dichas estaciones pertenencen a la Red de Estaciones Permanentes de EUREF (EUropean REference Framen) y constituyen el órden cero de la Geodesia Española

    Re-use of construction and demolition residues and industrial wastes for the elaboration or recycled eco-efficient concretes

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    [EN] Production of residues from industries and construction and demolition sectors has increased during last years. The total amount of debris produced according to different estimations reaches values close to 42 million tonnes yr –1 . Much of this waste has been thrown to landfill, without considering its potential for reuse, recycling or valuation. The aim of this research is to describe some of the physical and mechanical properties of different laboratory-mixed concretes, using various proportions of additional materials recovered from industrial waste and demolition rubble. The added materials are included either as admixtures (forestry residues, cork dust, steel fibre) or in partial substitution of natural aggregates (wire from electrical residues, tyre rubber, white ceramic, sanitary porcelain or shale). The laboratory tests have followed the standard EN protocols. Assay results were variable according to the nature of the material added to the mix: organic materials and shale, despite the steel fibre reinforcement, reduce the compression strength, but are suitable for the manufacture of lightweight concrete for agricultural pavements, with certain flexion resistance and a relatively good behaviour to impact. The substitution of natural aggregates with ceramic and porcelain wastes produces a significant increase in compression resistance, making them suitable for the manufacture of concrete with characteristic resistances above 40 MPa, which can be used both for structures or other agricultural elements: separators, feeders, slat floors. As a conclusion can be stated the possibility of reuse these wastes for the production of structural or non-structural concrete, with different applications in agricultural engineerin

    In Vivo and in vitro antitumor activity of tomatine in hepatocellular carcinoma

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    Background: There is abundant ethnopharmacological evidence the uses of regarding Solanum species as antitumor and anticancer agents. Glycoalkaloids are among the molecules with antiproliferative activity reported in these species. Purpose: To evaluate the anticancer effect of the Solanum glycoalkaloid tomatine in hepatocellular carcinoma (HCC) in vitro (HepG2 cells) and in vivo models. Methods: The resazurin reduction assay was performed to detect the effect of tomatine on cell viability in human HepG2 cell lines. Programmed cell death was investigated by means of cellular apoptosis assays using Annexin V. The expression of cancer related proteins was detected by Western blotting (WB). Reactive oxygen species (ROS) and calcium were determined by 2,7-dichlorodihydrofluorescein diacetate and Fluo-4, respectively. Intrahepatic HepG2 xenograft mouse model was used to elucidate the effect of tomatine on tumor growth in vivo. Results and Discussion: Tomatine reduced HepG2 cell viability and induced the early apoptosis phase of cell death, consistently with caspase-3, -7, Bcl-2 family, and P53 proteins activation. Furthermore, tomatine increased intracellular ROS and cytosolic Ca+2 levels. Moreover, the NSG mouse xenograft model showed that treating mice with tomatine inhibited HepG2 tumor growth. Conclusion: Tomatine inhibits in vitro and in vivo HCC tumorigenesis in part via modulation of p53, Ca+2, and ROS signalling. Thus, the results suggest the potential cancer therapeutic use of tomatine in HCC patients

    Failure under stress of grapevine wood: The effects of the cerambycid xylotrechus arvicola on the biomechanics properties of vitis vinifera

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    Xylotrechus arvicola is an insect pest on Vitis vinifera in the main wine-producing regions of Spain. X. arvicola larvae bore inside grapevine wood, which cause structural damages in the plants´ biomechanical properties. Grapevine wood affected and unaffected by larvae, were collected from vineyards. Compression and flexural tests were used to quantify biomechanical wood properties. Affected wood broke more quickly and endured a lower supported force than unaffected wood in both varieties and moisture states. Tempranillo was the most resistant variety on trunks, while Cabernet-Sauvignon was the most resistant variety on branches, where all infested varieties showed a lower rate of bending. Grapevine wood affected by X. arvicola larvae shows an important decrease in its resistance in both moisture states - dry and wet wood - and it is observed due to the faster break in time and a lower supported force. These damages give the affected wood greater sensitivity to external mechanical factors in the vineyards, such as strong winds, harvest weight and the vibration exerted by harvesting machines. The aspect of stress-time curves in all cases follow similar patterns, so in future studies might be possible to stablish relationships between both wet and dry samples and different infestation levels

    Estudio plurianual del efecto del régimen hídrico sobre la composición nitrogenada de las variedades blancas Cigüente, Macabeo, Moscatel de Alejandría y Verdejo, cultivadas en diversas regiones de España

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    Este trabajo analiza el efecto del régimen hídrico y del año sobre el perfil aminoacídico y el amonio de diferentes variedades blancas, conducidas en espaldera, en diferentes zonas vitícolas españolas. Las variedades, la localización y los tratamientos aplicados fueron: Cigüente (Ci) en Badajoz, secano y riego al 100% de ETc; Macabeo (Ma) en Albacete, 25% y 33% aprox de ETc; Moscatel de Alejandría (Mo) en Valencia, 50% y 100% de ETc; y Verdejo (Ve) en Valladolid, secano y 100% aprox. de ETc. En vendimia se analizó la composición aminoacídica y el amonio de la uva mediante HPLC y se calcularon el CTA (Contenido Amínico Total, mgL-1), aminoácidos asimilables (AA, mgL-1) y el YAN (Nitrógeno Fácilmente Asimilable por las levaduras). En Ci, Ma y Ve se hallaron diferencias significativas entre tratamientos para la mayoría de los aminoácidos. Debido a la variabilidad climática interanual observada, en la mayoría de ellos se encontró interacción significativa tratamiento*año, especialmente en Ci y Ma. La variación interanual y el efecto del riego fueron de poca amplitud y significación en Mo, observándose descensos en los valores medios de los aminoácidos individuales y de CTA y YAN en la uva de los tratamientos más regados. En Ma la aplicación de mayor dosis de agua durante el preenvero provocó aumentos en la mayoría de los aminoácidos, de mayor amplitud en 2014. En Ci la tendencia, amplitud y significación del efecto tratamiento dependió incluso de la campaña analizada para un determinado aminoácido. El riego en Ve disminuyó la concentración de los aminoácidos presentes en las bayas. Aunque no se ha logrado establecer un grupo de aminoácidos común para todas las variedades que pudieran servir de indicadores del estado hídrico de la cepa, los resultados hallados en Ci y Ve sugieren la existencia de patrones comunes para determinados grupos de variedades cuando los estados hídricos son similares
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