Review of \u3ci\u3ePrairie Republic: The Political Culture of Dakota Territory, 1879-1889\u3c/i\u3e by Jon K. Lauck

The Dakotas are often an overlooked and underexamined part of the United States. No one seems to know whether the region is part of the Midwest or the Real West, and so it often falls between the historiographical cracks. In this excellent study, Jon Lauck examines the political culture of the eastern region of South Dakota in the last decade before statehood. This period has been neglected by recent scholars, in part because it was often assumed that the standard work, Howard Lamar\u27s Dakota Territory, 1861-1889: A Study of Frontier Politics, published in 1956, had said the last word on the subject. But Lauck, while recognizing the strengths and contributions of Lamar\u27s study, also notes that, like all history, it was influenced by the preconceptions and the reigning historical orthodoxy of the era in which it was written and thus may merit reexamination more than a half-century later

Streaming Aerial Video Textures

We present a streaming compression algorithm for huge time-varying aerial imagery. New airborne optical sensors are capable of collecting billion-pixel images at multiple frames per second. These images must be transmitted through a low-bandwidth pipe requiring aggressive compression techniques. We achieve such compression by treating foreground portions of the imagery separately from background portions. Foreground information consists of moving objects, which form a tiny fraction of the total pixels. Background areas are compressed effectively over time using streaming wavelet analysis to compute a compact video texture map that represents several frames of raw input images. This map can be rendered efficiently using an algorithm amenable to GPU implementation. The core algorithmic contributions of this work are methods for fast, low-memory streaming wavelet compression and efficient display of wavelet video textures resulting from such compression

Characteristics and Motivational Factors of Effective Extension Advisory Leaders: Implications for Building Strong Extension Advisory Councils

The purpose of this study was to determine the characteristics and motivational factors of effective Extension advisory leaders. This Delphi study was conducted with a selected group of County Extension Directors and a group of Extension State Advisory Leaders. The study identified 10 characteristics that distinguish an effective Extension advisory leader. Some of these characteristics are explicit and easy to observe, while others are implicit and difficult to directly observe. Therefore, it is practical to use directly observable characteristics of effective advisory leaders when selecting volunteers. Once potential volunteers are spotted in the community, implicit characteristics of effective advisory leaders should be used to further screen them before they are selected. The study also identified the eight most important factors motivating individuals to volunteer as effective advisory leaders. Understanding these motivational factors is helpful for creating an environment for attracting and retaining effective volunteers. Understanding their motivation for volunteer work and creating an environment for them to meet the motivating factors for volunteering will lead to volunteer satisfaction and retention. The findings of this study can be used to build strong Extension advisory councils

Multiple FLC haplotypes defined by independent cis-regulatory variation underpin life history diversity in Arabidopsis thaliana

Relating molecular variation to phenotypic diversity is a central goal in evolutionary biology. In Arabidopsis thaliana, FLOWERING LOCUS C (FLC) is a major determinant of variation in vernalization—the acceleration of flowering by prolonged cold. Here, through analysis of 1307 A. thaliana accessions, we identify five predominant FLC haplotypes defined by noncoding sequence variation. Genetic and transgenic experiments show that they are functionally distinct, varying in FLC expression level and rate of epigenetic silencing. Allelic heterogeneity at this single locus accounts for a large proportion of natural variation in vernalization that contributes to adaptation of A. thaliana

Simulation of Urban Heat Island during a High-Heat Event Using WRF Urban Canopy Models: A Case Study for Metro Manila

This present study aims to determine the performance of using the Weather Research and Forecasting (WRF) Model, coupled with the urban canopy models (UCMs), in simulating the 2 m air temperature and 2 m relative humidity in Metro Manila. The simulation was performed during a high heat event on 22–29 April 2018, which coincided with the dry season in the Philippines. The four urban canopy model options that were used in this study include, the bulk (no urban), SLUCM, BEP, and BEM. The results of the simulations were compared with the hourly observations from three weather stations over Metro Manila from the National Oceanic and Atmospheric Administration Integrated Surface Dataset (ISD) and one agrometeorological station in Naic, Cavite. After model validation, the urban heat island (UHI) was then characterized to determine the spatial-temporal variations in the cities of Metro Manila. Statistical results show that the WRF simulation for 2 m air temperature agrees with measurements with an RMSE of0.80. WRF simulation for relative humidity still presents a challenge where simulation errors are higher than the acceptable range. The addition of UCMs does not necessarily improve the simulation for 2 m air temperature, while the use of BEP improved the 2 m relative humidity simulation. The results suggest the importance of using actual urban morphology values in WRF to accurately simulate near-surface variables. On the other hand, WRF simulation shows the presence of urban heat islands, notably in the northwest and central area of Metro Manila during daytime, extending throughout Metro Manila during nighttime. Lower air temperature was consistently observed in areas near Laguna Lake, while higher air temperature due to stagnant winds was observed in the northwest area of Metro Manila. High heat index was also observed throughout Metro Manila from daytime until nighttime, especially in areas near bodies of water like Manila Bay and Laguna Lake due to high humidity

Natural Bacterial Communities Serve as Quantitative Geochemical Biosensors

Biological sensors can be engineered to measure a wide range of environmental conditions. Here we show that statistical analysis of DNA from natural microbial communities can be used to accurately identify environmental contaminants, including uranium and nitrate at a nuclear waste site. In addition to contamination, sequence data from the 16S rRNA gene alone can quantitatively predict a rich catalogue of 26 geochemical features collected from 93 wells with highly differing geochemistry characteristics. We extend this approach to identify sites contaminated with hydrocarbons from the Deepwater Horizon oil spill, finding that altered bacterial communities encode a memory of prior contamination, even after the contaminants themselves have been fully degraded. We show that the bacterial strains that are most useful for detecting oil and uranium are known to interact with these substrates, indicating that this statistical approach uncovers ecologically meaningful interactions consistent with previous experimental observations. Future efforts should focus on evaluating the geographical generalizability of these associations. Taken as a whole, these results indicate that ubiquitous, natural bacterial communities can be used as in situ environmental sensors that respond to and capture perturbations caused by human impacts. These in situ biosensors rely on environmental selection rather than directed engineering, and so this approach could be rapidly deployed and scaled as sequencing technology continues to become faster, simpler, and less expensive

The Next WHO Director-General’s Highest Priority: a Global Treaty on the Human Right to Health

Amidst the many challenges facing the next WHO Director-General, the new WHO head should find WHO’s foremost priority in its most important constitutional pillar: the right to health. The centerpiece of this endeavor should be leadership on the Framework Convention on Global Health (FCGH), the proposed global treaty based in the right to health and aimed at national and global health equity. The treaty would reform global governance for health to enhance accountability, transparency, and civil society participation and protect the right to health in trade, investment, climate change, and other international regimes, while catalyzing governments to institutionalize the right to health at community through to national levels. It would usher in a new era of global health with justice – vast improvements in health outcomes, equitably distributed. With the Framework Convention on Tobacco Control having served as a proof of concept, the FCGH would be an innovative treaty finding solutions to overcome global health failings in accountability, equality, financing, and inter-sectoral coherence. It would include a global health accountability framework, encompassing, civil society engagement, independent monitoring, and plans for redress, while catalyzing national health accountability strategies, accountability mechanisms, disaggregated data, and community participation. National health equity strategies, pro-poor pathways to universal health coverage, and robust non-discrimination provisions could elevate the voices, priorities, and ultimately power of marginalized populations. The FCGH would include a national and global health financing framework, while reaching beyond the health sector with right to health assessments, public health participation in developing international agreements, and responsibility for all sectors for improving health outcomes. The FCGH would reinvigorate WHO’s global health leadership, breathing new life into its founding principles. It could become the platform for reforming WHO as a rights-based 21st century institution, with badly-needed reforms, such as community participation, new priorities favouring social determinants of health, and a culture of transparency and accountability. The next Director-General should launch a historic effort to align national and global governance for with human rights through the FCGH, bringing the world closer to global health with justice

Adverse Events of Interest Following Influenza Vaccination in the First Season of Adjuvanted Trivalent Immunization:Retrospective Cohort Study

BACKGROUND: Vaccination is the most effective form of prevention of seasonal influenza; the United Kingdom has a national influenza vaccination program to cover targeted population groups. Influenza vaccines are known to be associated with some common minor adverse events of interest (AEIs), but it is not known if the adjuvanted trivalent influenza vaccine (aTIV), first offered in the 2018/2019 season, would be associated with more AEIs than other types of vaccines. OBJECTIVE: We aim to compare the incidence of AEIs associated with different types of seasonal influenza vaccines offered in the 2018/2019 season. METHODS: We carried out a retrospective cohort study using computerized medical record data from the Royal College of General Practitioners Research and Surveillance Centre sentinel network database. We extracted data on vaccine exposure and consultations for European Medicines Agency–specified AEIs for the 2018/2019 influenza season. We used a self-controlled case series design; computed relative incidence (RI) of AEIs following vaccination; and compared the incidence of AEIs associated with aTIV, the quadrivalent influenza vaccine, and the live attenuated influenza vaccine. We also compared the incidence of AEIs for vaccinations that took place in a practice with those that took place elsewhere. RESULTS: A total of 1,024,160 individuals received a seasonal influenza vaccine, of which 165,723 individuals reported a total of 283,355 compatible symptoms in the 2018/2019 season. Most AEIs occurred within 7 days following vaccination, with a seasonal effect observed. Using aTIV as the reference group, the quadrivalent influenza vaccine was associated with a higher incidence of AEIs (RI 1.46, 95% CI 1.41-1.52), whereas the live attenuated influenza vaccine was associated with a lower incidence of AEIs (RI 0.79, 95% CI 0.73-0.83). No effect of vaccination setting on the incidence of AEIs was observed. CONCLUSIONS: Routine sentinel network data offer an opportunity to make comparisons between safety profiles of different vaccines. Evidence that supports the safety of newer types of vaccines may be reassuring for patients and could help improve uptake in the future

Comparative study of physical activity patterns among school children in Kenya and Canada: Results from the ISCOLE Project

Abstract Examination of the timing and patterns of daily activity are crucial in understanding when children accumulate the highest levels of physical activity. The objectives of this study were to examine moderate-to-vigorous physical activity (MVPA) patterns accrued by time of day among Kenyan children, and compare activity patterns in Kenya to those of Canadian children. Physical activity and body weights of participating children were measured by accelerometry and anthropometry, while supplementary self-report data were captured by questionnaires. Data were collected as part of a larger International Study of Childhood Obesity, Lifestyle and Environment (ISCOLE) in Nairobi for ISCOLE-Kenya and in the Ottawa Region for ISCOLE-Canada. A total of 555 Kenyan and 541 Canadian children 9 to 11 years were included in the analyses. In Kenya, boys, under/healthy weight, and children attending public (lower socioeconomic status (SES)) schools were found to have significantly higher MVPA levels compared to girls, overweight/obese, and children attending private (higher SES) schools respectively. MVPA on weekdays was higher than on weekend-days. Activity profiles among Kenyan and Canadian children were very similar; however, Kenyan children had significantly higher MVPA and lower sedentary time on weekend-days. MVPA patterns among urban Kenyan children were largely similar to those of urban Canadian children when assessed by sex, BMI category, and weekday/weekend days. However, in the Kenyan sample, unlike in many higher income countries, lower SES was associated with higher MVPA