234 research outputs found
AAV-mediated expression of anti-tau scFvs decreases tau accumulation in a mouse model of tauopathy
Tauopathies are characterized by the progressive accumulation of hyperphosphorylated, aggregated forms of tau. Our laboratory has previously demonstrated that passive immunization with an anti-tau antibody, HJ8.5, decreased accumulation of pathological tau in a human P301S tau-expressing transgenic (P301S-tg) mouse model of frontotemporal dementia/tauopathy. To investigate whether the
N=3 Warped Compactifications
Orientifolds with three-form flux provide some of the simplest string
examples of warped compactification. In this paper we show that some models of
this type have the unusual feature of D=4, N=3 spacetime supersymmetry. We
discuss their construction and low energy physics. Although the local form of
the moduli space is fully determined by supersymmetry, to find its global form
requires a careful study of the BPS spectrum.Comment: 27 pages, v2: 32pp., RevTeX4, fixed factors, slightly improved
sections 3D and 4B, v3: added referenc
Type IIA Orientifolds on General Supersymmetric Z_N Orbifolds
We construct Type IIA orientifolds for general supersymmetric Z_N orbifolds.
In particular, we provide the methods to deal with the non-factorisable
six-dimensional tori for the cases Z7, Z8, Z8', Z12 and Z12'. As an application
of these methods we explicitly construct many new orientifold models.Comment: 48 pages, LaTeX, 14 figures, refs. added, closed string spectra
slightly change
A search for ferromagnetism in transition-metal-doped piezoelectric ZnO
We present the results of a computational study of ZnO in the presence of Co
and Mn substitutional impurities. The goal of our work is to identify potential
ferromagnetic ground states within the (Zn,Co)O or (Zn,Mn)O material systems
that are also good candidates for piezoelectricity. We find that, in contrast
to previous results, robust ferromagnetism is not obtained by substitution of
Co or Mn on the Zn site, unless additional carriers (holes) are also
incorporated. We propose a practical scheme for achieving such -type doping
in ZnO
Charge Deficiency, Charge Transport and Comparison of Dimensions
We study the relative index of two orthogonal infinite dimensional
projections which, in the finite dimensional case, is the difference in their
dimensions. We relate the relative index to the Fredholm index of appropriate
operators, discuss its basic properties, and obtain various formulas for it. We
apply the relative index to counting the change in the number of electrons
below the Fermi energy of certain quantum systems and interpret it as the
charge deficiency. We study the relation of the charge deficiency with the
notion of adiabatic charge transport that arises from the consideration of the
adiabatic curvature. It is shown that, under a certain covariance,
(homogeneity), condition the two are related. The relative index is related to
Bellissard's theory of the Integer Hall effect. For Landau Hamiltonians the
relative index is computed explicitly for all Landau levels.Comment: 23 pages, no figure
Longitudinal double-spin asymmetry and cross section for inclusive neutral pion production at midrapidity in polarized proton collisions at sqrt(s) = 200 GeV
We report a measurement of the longitudinal double-spin asymmetry A_LL and
the differential cross section for inclusive Pi0 production at midrapidity in
polarized proton collisions at sqrt(s) = 200 GeV. The cross section was
measured over a transverse momentum range of 1 < p_T < 17 GeV/c and found to be
in good agreement with a next-to-leading order perturbative QCD calculation.
The longitudinal double-spin asymmetry was measured in the range of 3.7 < p_T <
11 GeV/c and excludes a maximal positive gluon polarization in the proton. The
mean transverse momentum fraction of Pi0's in their parent jets was found to be
around 0.7 for electromagnetically triggered events.Comment: 6 pages, 3 figures, submitted to Phys. Rev. D (RC
Evolution of the differential transverse momentum correlation function with centrality in Au+Au collisions at GeV
We present first measurements of the evolution of the differential transverse
momentum correlation function, {\it C}, with collision centrality in Au+Au
interactions at GeV. {\it C} exhibits a strong dependence
on collision centrality that is qualitatively similar to that of number
correlations previously reported. We use the observed longitudinal broadening
of the near-side peak of {\it C} with increasing centrality to estimate the
ratio of the shear viscosity to entropy density, , of the matter formed
in central Au+Au interactions. We obtain an upper limit estimate of
that suggests that the produced medium has a small viscosity per unit entropy.Comment: 7 pages, 4 figures, STAR paper published in Phys. Lett.
High non-photonic electron production in + collisions at = 200 GeV
We present the measurement of non-photonic electron production at high
transverse momentum ( 2.5 GeV/) in + collisions at
= 200 GeV using data recorded during 2005 and 2008 by the STAR
experiment at the Relativistic Heavy Ion Collider (RHIC). The measured
cross-sections from the two runs are consistent with each other despite a large
difference in photonic background levels due to different detector
configurations. We compare the measured non-photonic electron cross-sections
with previously published RHIC data and pQCD calculations. Using the relative
contributions of B and D mesons to non-photonic electrons, we determine the
integrated cross sections of electrons () at 3 GeV/10 GeV/ from bottom and charm meson decays to be = 4.0({\rm
stat.})({\rm syst.}) nb and =
6.2({\rm stat.})({\rm syst.}) nb, respectively.Comment: 17 pages, 17 figure
Measurement of the Bottom contribution to non-photonic electron production in collisions at =200 GeV
The contribution of meson decays to non-photonic electrons, which are
mainly produced by the semi-leptonic decays of heavy flavor mesons, in
collisions at 200 GeV has been measured using azimuthal
correlations between non-photonic electrons and hadrons. The extracted
decay contribution is approximately 50% at a transverse momentum of GeV/. These measurements constrain the nuclear modification factor for
electrons from and meson decays. The result indicates that meson
production in heavy ion collisions is also suppressed at high .Comment: 6 pages, 4 figures, accepted by PR
The Behavioral Roots of Information Systems Security:Exploring Key Factors Related to Unethical IT Use
Unethical information technology (IT) use, related to activities such as hacking, software piracy, phishing, and spoofing, has become a major security concern for individuals, organizations, and society in terms of the threat to information systems (IS) security. While there is a growing body of work on this phenomenon, we notice several gaps, limitations, and inconsistencies in the literature. In order to further understand this complex phenomenon and reconcile past findings, we conduct an exploratory study to uncover the nomological network of key constructs salient to this phenomenon, and the nature of their interrelationships. Using a scenario-based study of young adult participants, and both linear and nonlinear analyses, we uncover key nuances of this phenomenon of unethical IT use. We find that unethical IT use is a complex phenomenon, often characterized by nonlinear and idiosyncratic relationships between the constructs that capture it. Overall, ethical beliefs held by the individuals, along with economic, social, and technological considerations are found to be relevant to this phenomenon. In terms of practical implications, these results suggest that multiple interventions at various levels may be required to combat this growing threat to IS security
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