501 research outputs found

    Enabling FAIR Data Principles in the Era of Big Data. Strategies, challenges and implications

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    Universitat de Barcelona. Facultat d'Informació i Mitjans Audiovisuals . Presentació de l’alumnat de GIDD i INFOCOM al Congrés BOBCATSSS 2024, Curs: 2023-2024, Director: Boté-Vericad, Juan-JoséPresentació de l’alumnat de GIDD i INFOCOM al Congrés BOBCATSSS 2024, el congrés internacional adreçat a alumnat i professorat de Gestió d'Informació i Documentació Digital d'arreu, celebrat a Coimbra (Portugal), del 23 al 25 de gener del 2024

    User interaction modeling and profile extraction in interactive systems : a groupware application case study

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    Abstract A relevant goal in human-computer interaction is to produce applications that are easy to use and well-adjusted to their users' needs. To address this problem it is important to know how users interact with the system. This work constitutes a methodological contribution capable of identifying the context of use in which users perform interactions with a groupware application (synchronous or asynchronous) and provides, using machine learning techniques, generative models of how users behave. Additionally, these models are transformed into a text that describes in natural language the main characteristics of the interaction of the users with the system.This work was partially supported by project PAC::LFO (MTM2014-55262-P) of Ministerio de Ciencia e Innovación (MICINN), Spain. We are grateful to the referees for their constructive input

    Energetic metabolism in fasting sheep: regularization of metabolic profile by treatment with oral glucose, with prior handling of gastric groove

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    The objective of this research was to evaluate a possible corrective measure against negative metabolic states, as occurs in the advanced stage of gestation in ewes, and that sometimes produces a disease called pregnancy toxaemia. In the present research, we found that the joint administration of i.v. lysine-vasopressin (0.08 IU/kg body weight, BW) and an oral glucose solution (50 g) produces an increase in blood glucose, which persists for some time (up to 6 h); therefore, it could be used in the treatment of pregnancy toxaemia. This therapy is based on the fact that lysine-vasopressin induces gastric groove closure in adult ruminants, enabling orally administered glucose to reach the abomasum directly, from where it rapidly passes into the intestine and is immediately absorbed. We can say that the tested treatment causes a significant increase in blood glucose in ewes affected by toxaemia caused by fasting, which, although less marked than conventional therapy with intravenous drip glucose, remains longer, regularizing other parameters indicative of energy metabolism in fasting ewes

    ¿Coinciden los espacios naturales protegidos con las áreas relevantes de diversidad de herpetofauna en España peninsular y Baleares?

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    Debido a los elevados costes de la conservación, es importante priorizar áreas de actuación que permitan optimizar la inversión realizada. En este trabajo se identifican las áreas relevantes de biodiversidad de anfibios y reptiles en España peninsular e Islas Baleares. Para identificar estas áreas se han usado cuatro criterios, que proporcionaron distintos grados de eficacia o inclusión de especies, particularmente las amenazadas, en las áreas relevantes definidas por ellos. Se examina también la coincidencia geográfica entre dichas áreas relevantes y la red de Espacios Naturales Protegidos (ENPs), detectándose una serie de huecos que se propone completar con nuevos ENPs. Más allá de la explicación de la distribución de las áreas relevantes de biodiversidad, donde intervienen procesos ecológicos y evolutivos, creemos que estudios como éste pueden ayudar a la identificación de zonas del territorio especialmente valiosas para la conservación de la biodiversidad.Estas investigaciones se han beneficiado parcialmente del proyecto "Factores limitantes de la revegetación con especies leñosas autóctonas de áreas degradadas en ambientes mediterráneos. Rendimiento de distintas actuaciones de manejo" (REN2000 745) de la CICYT

    Characterization of free nitrogen fixing bacteria of the genus Azotobacter in organic vegetable-grown Colombian soils

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    With the purpose of isolating and characterizing free nitrogen fixing bacteria (FNFB) of the genus Azotobacter, soil samples were collected randomly from different vegetable organic cultures with neutral pH in different zones of Boyacá-Colombia. Isolations were done in selective free nitrogen Ashby-Sucrose agar obtaining a recovery of 40%. Twenty four isolates were evaluated for colony and cellular morphology, pigment production and metabolic activities. Molecular characterization was carried out using amplified ribosomal DNA restriction analysis (ARDRA). After digestion of 16S rDNA Y1-Y3 PCR products (1487pb) with AluI, HpaII and RsaI endonucleases, a polymorphism of 16% was obtained. Cluster analysis showed three main groups based on DNA fingerprints. Comparison between ribotypes generated by isolates and in silico restriction of 16S rDNA partial sequences with same restriction enzymes was done with Gen Workbench v.2.2.4 software. Nevertheless, Y1-Y2 PCR products were analysed using BLASTn. Isolate C5T from tomato (Lycopersicon esculentum) grown soils presented the same in silico restriction patterns with A. chroococcum (AY353708) and 99% of similarity with the same sequence. Isolate C5CO from cauliflower (Brassica oleracea var. botrytis) grown soils showed black pigmentation in Ashby-Benzoate agar and high similarity (91%) with A. nigricans (AB175651) sequence. In this work we demonstrated the utility of molecular techniques and bioinformatics tools as a support to conventional techniques in characterization of the genus Azotobacter from vegetable-grown soils

    Validación de modelos genéticos en bioinformática: implementación y visualización

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    Programa de Doctorado en Biotecnología, Ingeniería y Tecnología QuímicaLínea de Investigación: Ingeniería, Ciencia de Datos y BioinformáticaClave Programa: DBICódigo Línea: 111Since the human genome was completely sequenced for the first time, the great scientific and technological advances in the biotechnology industry have greatly reduced the cost of experiments while significantly improving results. This has led to an exponential growth in the biological information available and, due to this huge amount of information, researchers are faced with mountains of data with only flakes of knowledge. Approaches as Knowledge Database Discovery (KDD) are used to generate models that allows researcher to gain knowledge about complex biological systems. Gene networks arose as a straightforward way of representing gene sets including their interactions. They are presented as a network structure where each node represents a gene or gene product (protein) while each edge denotes the relationship between the nodes at its ends. The concrete nature of each relationship and the meaning of its weight depend on the network architecture and the inference algorithm used. A gene network is an abstraction that facilitates the study of its underlying biological system. They are easy to visualize, and they are informative on their own. Gene networks have been successfully used in clinical diagnosis and a large number of inferred interactions have been confirmed experimentally, thus confirming their reliability. The inference of gene networks has also allowed a better understanding of fundamental processes that occur in living organisms such as development or nutrition and metabolic coordination. Research has focused on inferring these networks using different experimental and computational techniques, as well as analyzing those networks to extract knowledge. Also, a significant number of methods have been developed to validate the inferred networks in order to verify their quality and reliability. All the methodologies of gene network inference, analysis, and validation are based on algorithms and computer tools. Given the increasing importance and popularity of these computational approaches, it becomes increasingly critical to ensure that the software is usable and accessible, as these features provide the basis for the reproducibility of published biomedical research. Based on the existing need for automatic techniques of inference, analysis and validation of models for the study of interactions between genes and the deficiencies in existing techniques, this work presents different novel approaches for the inference, analysis and validation of genetic models, especially gene networks, with a special emphasis on the usability and accessibility of the proposed solutions.Universidad Pablo de Olavide de Sevilla. Escuela de Doctorad

    De cómo Felipe II no mandó matar a Escobedo

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    Copia digital. Valladolid : Junta de Castilla y León. Consejería de Cultura y Turismo, 201

    Scalability of the channel capacity in graphene-enabled wireless communications to the nanoscale

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    Graphene is a promising material which has been proposed to build graphene plasmonic miniaturized antennas, or graphennas, which show excellent conditions for the propagation of Surface Plasmon Polariton (SPP) waves in the terahertz band. Due to their small size of just a few micrometers, graphennas allow the implementation of wireless communications among nanosystems, leading to a novel paradigm known as Graphene-enabled Wireless Communications (GWC). In this paper, an analytical framework is developed to evaluate how the channel capacity of a GWC system scales as its dimensions shrink. In particular, we study how the unique propagation of SPP waves in graphennas will impact the channel capacity. Next, we further compare these results with respect to the case when metallic antennas are used, in which these plasmonic effects do not appear. In addition, asymptotic expressions for the channel capacity are derived in the limit when the system dimensions tend to zero. In this scenario, necessary conditions to ensure the feasibility of GWC networks are found. Finally, using these conditions, new guidelines are derived to explore the scalability of various parameters, such as transmission range and transmitted power. These results may be helpful for designers of future GWC systems and networks.Peer ReviewedPostprint (author’s final draft
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