680 research outputs found
GLAD: Global-Local View Alignment and Background Debiasing for Unsupervised Video Domain Adaptation with Large Domain Gap
In this work, we tackle the challenging problem of unsupervised video domain
adaptation (UVDA) for action recognition. We specifically focus on scenarios
with a substantial domain gap, in contrast to existing works primarily deal
with small domain gaps between labeled source domains and unlabeled target
domains. To establish a more realistic setting, we introduce a novel UVDA
scenario, denoted as Kinetics->BABEL, with a more considerable domain gap in
terms of both temporal dynamics and background shifts. To tackle the temporal
shift, i.e., action duration difference between the source and target domains,
we propose a global-local view alignment approach. To mitigate the background
shift, we propose to learn temporal order sensitive representations by temporal
order learning and background invariant representations by background
augmentation. We empirically validate that the proposed method shows
significant improvement over the existing methods on the Kinetics->BABEL
dataset with a large domain gap. The code is available at
https://github.com/KHUVLL/GLAD.Comment: This is an accepted WACV 2024 paper. Our code is available at
https://github.com/KHUVLL/GLA
The Fruit Hull of Gleditsia sinensis
Lung cancer has substantial mortality worldwide, and chemotherapy is a routine regimen for the treatment of patients with lung cancer, despite undesirable effects such as drug resistance and chemotoxicity. Here, given a possible antitumor effect of the fruit hull of Gleditsia sinensis (FGS), we tested whether FGS enhances the effectiveness of cis-diammine dichloridoplatinum (II) (CDDP), a chemotherapeutic drug. We found that CDDP, when administered with FGS, significantly decreased the viability and increased the apoptosis and cell cycle arrest of Lewis lung carcinoma (LLC) cells, which were associated with the increase of p21 and decreases of cyclin D1 and CDK4. Concordantly, when combined with FGS, CDDP significantly reduced the volume and weight of tumors derived from LLC subcutaneously injected into C57BL/6 mice, with concomitant increases of phosphor-p53 and p21 in tumor tissue. Together, these results show that FGS could enhance the antitumor activity of CDDP, suggesting that FGS can be used as a complementary measure to enhance the efficacy of a chemotherapeutic agent such as CDDP
Investigating the potential association of temporary employment and job dissatisfaction with alcohol use disorder and depressive symptoms: a 13-wave longitudinal analysis
Background
There has been growing interest in protecting workers’ mental health. Identifying social determinants that affect workers’ mental health could play an important role in preventing psychiatric diseases.
Aims
We investigated the effects of temporary employment and job dissatisfaction on alcohol use disorder and depressive symptoms.
Method
The Korea Welfare Panel Study data-set (2009–2021) was used, and 9611 participants with 52 639 observations were included. Generalised linear mixed models were employed to estimate odds ratios and 95% confidence intervals. The relative excess risk due to interaction (RERI) was calculated to assess supra-additive interactions between temporary employment and job dissatisfaction.
Results
Increased risks for depressive symptoms were observed among fixed-term workers (odds ratio 1.12, 95% CI 1.00–1.26) and daily labourers (odds ratio 1.68, 95% CI 1.44–1.95). Daily labourers were associated with an increased risk of alcohol use disorder (odds ratio 1.54, 95% CI 1.22–1.95). Job dissatisfaction was associated with alcohol use disorder (odds ratio 1.78, 95% CI 1.52–2.08) and depressive symptoms (odds ratio 4.88, 95% CI 4.36–5.46). This effect became stronger when workers were concurrently exposed to temporary employment and job dissatisfaction. Daily labourers with job dissatisfaction showed the highest risks for alcohol use disorder (odds ratio 2.99, 95% CI 2.21–4.03) and depressive symptoms (odds ratio 9.00, 95% CI 7.36–11.02). RERIs between daily employment and job dissatisfaction were >0 for alcohol use disorder (0.91, 95% CI 0.06–1.76) and depressive symptoms (3.47, 95% CI 1.80–5.14), indicating a supra-additive interaction.
Conclusions
We revealed that temporary employment and job dissatisfaction had detrimental effects on alcohol use disorder and depressive symptoms
The role of work–family conflict in the association between long working hours and workers’ sleep disturbance and burnout: results from the sixth Korean Working Conditions Survey
Background
The effect of long working hours on mental health has drawn great social attention in recent years.
Aims
We investigated how work–family conflict mediates the associations between long working hours and sleep disturbance and burnout.
Method
We included 19 159 individuals from a nationally representative sample of workers in South Korea. We decomposed the total effect into a direct effect (long working hours → sleep disturbance or burnout) and an indirect effect (long working hours → work–family conflict → sleep disturbance or burnout). Logistic mediation models were used.
Results
Long working hours were associated with increased risks of work–family conflict, sleep disturbance and burnout. The longer the working hours, the stronger the direct and indirect effects. The odds ratios of the direct effects of long working hours on sleep disturbance were 1.64 (95% CI 1.39–1.95) for 49–54 h/week and 1.66 (95% CI 1.37–2.01) for ≥55 h/week; those of the indirect effects were 1.16 (95% CI 1.12–1.21) for 49–54 h/week and 1.27 (95% CI 1.21–1.33) for ≥ 55 h/week. Similarly, odds ratios of the direct effects of long working hours on burnout were 1.18 (95% CI 1.05–1.33) for 49–54 h/week and 1.20 (95% CI 1.04–1.37) for ≥55 h/week; those of the indirect effects were 1.11 (95% CI 1.09–1.15) for 49–54 h/week and 1.20 (95% CI 1.16–1.24) for ≥55 h/week.
Conclusions
Our results suggest that work–family conflict mediates the associations between long working hours and sleep disturbance and burnout. Longitudinal studies should be followed to confirm the causal relationship
SoEasy: A Software Framework for Easy Hardware Control Programming for Diverse IoT Platforms
Many Internet of Things (IoT) applications are emerging and evolving rapidly thanks to widespread open-source hardware platforms. Most of the high-end open-source IoT platforms include built-in peripherals, such as the universal asynchronous receiver and transmitter (UART), pulse width modulation (PWM), general purpose input output (GPIO) ports and timers, and have enough computation power to run embedded operating systems such as Linux. However, each IoT platform has its own way of configuring peripherals, and it is difficult for programmers or users to configure the same peripheral on a different platform. Although diverse open-source IoT platforms are widespread, the difficulty in programming those platforms hinders the growth of IoT applications. Therefore, we propose an easy and convenient way to program and configure the operation of each peripheral using a user-friendly Web-based software framework. Through the implementation of the software framework and the real mobile robot application development along with it, we show the feasibility of the proposed software framework, named SoEasy
C-Band GaN Dual-Feedback Low-Noise Amplifier MMIC with High-Input Power Robustness
In this paper, using the 0.2 μm ETRI GaN HEMT process, we developed a C-band GaN dual-feedback low-noise amplifier MMIC for an RF receiver module that requires high-input power robustness. By applying a feedback microstrip line at the source of the transistor and series resistor-capacitor (RC) feedback between the gate and the drain of the transistor, we obtained stable amplifier operation and a compromised impedance trace for both input impedance matching and noise matching while suppressing performance degradation of the maximum available gain and minimum noise figure. The developed low-noise amplifier MMIC, which implements simple matching circuits by using biasing elements as matching elements, had a linear gain of more than 21.4 dB and a noise figure of less than 1.91 dB in the wide bandwidth of 4.3–7.4 GHz. Under the single-tone power test, the low-noise amplifier MMIC had an output P1dB of 14.3–20.1 dBm, and the two-tone intermodulation distortion measurement exhibited an input third-order intercept point (IIP3) of 2.2–5.6 dBm in the same frequency range as the above
Specific Radius Change of Quantum Dot inside the Lipid Bilayer by Charge Effect of Lipid Head-Group
We studied the quantum dot-liposome complex (QLC), which is the giant unilamellar vesicle with quantum dots (QDs) incorporated in its lipid bilayer. A spin coating method in conjunction with the electroformation technique yielded vesicles with highly homogeneous unilamellar structure. We observed QD size dependence of the QLC formation: QLCs form with blue, green and yellow-emission QD (core radius ~1.05 nm, 1.25 nm and 1.65 nm) but not with red-emission QD (core radius ~2.5 nm). In order to explain this size dependence, we made a simple model explaining the QD size effect on QLC formation in terms of the molecular packing parameter and the lipid conformational change. This model predicts that QDs below a certain critical size (radius ≈ 1.8 nm) can stably reside in a lipid bilayer of 4 - 5 nm in thickness for Egg-PC lipids. This is consistent with our previous experimental results. In the case of red-emission QD, QD-aggregations are only observed on the fluorescent microscopy instead of QLC. We expected that the reduction of packing parameter (P) would lead to the change of specific QD radius. This prediction could be verified by our experimental observation of the shift of the specific QD size by mixing DOPG
Optical Shaping of Plasma Cavity for Controlled Laser Wakefield Acceleration
Laser wakefield accelerators rely on relativistically moving micron-sized
plasma cavities that provide extremely high electric field >100GV/m. Here, we
demonstrate transverse shaping of the plasma cavity to produce controlled
sub-GeV electron beams, adopting laser pulses with an axially rotatable
ellipse-shaped focal spot. We showed the control capability on electron
self-injection, charge, and transverse profile of the electron beam by rotating
the focal spot. We observed that the effect of the elliptical focal spot was
imprinted in the profiles of the electron beams and the electron energy
increased, as compared to the case of a circular focal spot. We performed 3D
particle-in-cell (PIC) simulations which reproduced the experimental results
and revealed dynamics of a new asymmetric self-injection process. This simple
scheme offers a novel control method on laser wakefield acceleration to produce
tailored electron beams and x-rays for various applications.Comment: 5 pages, 5 figure
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