1,434 research outputs found
The key aspects of innovation-oriented regional industrial and economic policy
Integration processes taking place in the economy, the new requirements to enhance the effectiveness of production during international competition as well as the need to ensure the social conditions lead to the development and implementation of innovation-oriented regional industrial and economic policy, which in its turn, requires adopting substantial organizational and economic recommendations
Changes in the radiographic characteristics of the mandibular alveolar process in dentate women with varying bone mineral density: A 5-years prospective study
Design and development of a low temperature, inductance based high frequency ac susceptometer
We report on the development of an induction based low temperature high
frequency ac susceptometer capable of measuring at frequencies up to 3.5 MHz
and at temperatures between 2 K and 300 K. Careful balancing of the detection
coils and calibration have allowed a sample magnetic moment resolution of
at 1 MHz. We will discuss the design and
characterization of the susceptometer, and explain the calibration process. We
also include some example measurements on the spin ice material CdErS
and iron oxide based nanoparticles to illustrate functionality
Fish oil in infancy protects against food allergy in Iceland-Results from a birth cohort study
To access publisher's full text version of this article, please click on the hyperlink in Additional Links field or click on the hyperlink at the top of the page marked FilesBACKGROUND: Consumption of oily fish or fish oil during pregnancy, lactation and infancy has been linked to a reduction in the development of allergic diseases in childhood. METHODS: In an observational study, Icelandic children (n = 1304) were prospectively followed from birth to 2.5 years with detailed questionnaires administered at birth and at 1 and 2 years of age, including questions about fish oil supplementation. Children with suspected food allergy were invited for physical examinations, allergic sensitization tests, and a double-blind, placebo-controlled food challenge if the allergy testing or clinical history indicated food allergy. The study investigated the development of sensitization to food and confirmed food allergy according to age and frequency of postnatal fish oil supplementation using proportional hazards modelling. RESULTS: The incidence of diagnosed food sensitization was significantly lower in children who received regular fish oil supplementation (relative risk: 0.51, 95% confidence interval: 0.32-0.82). The incidence of challenge-confirmed food allergy was also reduced, although not statistically significant (0.57, 0.30-1.12). Children who began to receive fish oil in their first half year of life were significantly more protected than those who began later (P = .045 for sensitization, P = .018 for allergy). Indicators of allergy severity decreased with increased fish oil consumption (P = .013). Adjusting for parent education and allergic family history did not change the results. CONCLUSION: Postnatal fish oil consumption is associated with decreased food sensitization and food allergies in infants and may provide an intervention strategy for allergy prevention.European Commission
Landspitali University Hospital Science Fund
GlaxoSmithKline Icelan
Reconstruction of Random Colourings
Reconstruction problems have been studied in a number of contexts including
biology, information theory and and statistical physics. We consider the
reconstruction problem for random -colourings on the -ary tree for
large . Bhatnagar et. al. showed non-reconstruction when and reconstruction when . We tighten this result and show non-reconstruction when and reconstruction when .Comment: Added references, updated notatio
Adding Mirabegron to Solifenacin to Treat Overactive Bladder Has Little Impact on Post-Void Residual Volume or Urinary Retention Risk
Impacts de la conductivité hydraulique sur la biofiltration des eaux pluviales : étude de la conception, du fonctionnement et du suivi de jardins d'eau utilisant différents systèmes de filtration à Sydney, Australie
Spectroscopic and in vitro Investigations of Fe2+/alpha-Ketoglutarate-Dependent Enzymes Involved in Nucleic Acid Repair and Modification
The activation of molecular oxygen for the highly selective functionalization and repair of DNA and RNA nucleobases is achieved by alpha-ketoglutarate (alpha-KG)/iron-dependent dioxygenases. Of special interest are the human homologues AlkBH of Escherichia coli EcAlkB and ten-eleven translocation (TET) enzymes. These enzymes are involved in demethylation or dealkylation of DNA and RNA, although additional physiological functions are continuously being found. Given their importance, studying enzyme-substrate interactions, turnover and kinetic parameters is pivotal for the understanding of the mode of action of these enzymes. Diverse analytical methods, including X-ray crystallography, UV/Vis absorption, electron paramagnetic resonance (EPR), circular dichroism (CD) and nuclear magnetic resonance (NMR) spectroscopy have been employed to study the changes in the active site and the overall enzyme structure upon substrate, cofactor, and inhibitor addition. Several methods are now available to assess the activity of these enzymes. By discussing limitations and possibilities of these techniques for EcAlkB, AlkBH and TET we aim to give a comprehensive synopsis from a bioinorganic point-of-view, addressing researchers from different disciplines working in the highly interdisciplinary and rapidly evolving field of epigenetic processes and DNA/RNA repair and modification
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