539 research outputs found
Running spectral index from shooting-star moduli
We construct an inflationary model that is consistent with both large
non-Gaussianity and a running spectral index. The scenario of modulated
inflation suggests that modulated perturbation can induce the curvature
perturbation with a large non-Gaussianity, even if the inflaton perturbation is
negligible. Using this idea, we consider a multi-field extension of the
modulated inflation scenario and examine the specific situation where different
moduli are responsible for the perturbation at different scales. We suppose
that the additional moduli (shooting-star moduli) is responsible for the
curvature perturbation at the earlier inflationary epoch and it generates the
fluctuation with n>1 spectral index at this scale. After a while, another
moduli (or inflaton) takes the place and generates the perturbation with n<1.
At the transition point the two fluctuations are comparable with each other. We
show how the spectral index is affected by the transition induced by the
shooting-star moduli.Comment: 14 pages, latex, accepted for publication in JHE
Proton Drip-Line Calculations and the Rp-process
One-proton and two-proton separation energies are calculated for proton-rich
nuclei in the region . The method is based on Skyrme Hartree-Fock
calculations of Coulomb displacement energies of mirror nuclei in combination
with the experimental masses of the neutron-rich nuclei. The implications for
the proton drip line and the astrophysical rp-process are discussed. This is
done within the framework of a detailed analysis of the sensitivity of rp
process calculations in type I X-ray burst models on nuclear masses. We find
that the remaining mass uncertainties, in particular for some nuclei with
, still lead to large uncertainties in calculations of X-ray burst light
curves. Further experimental or theoretical improvements of nuclear mass data
are necessary before observed X-ray burst light curves can be used to obtain
quantitative constraints on ignition conditions and neutron star properties. We
identify a list of nuclei for which improved mass data would be most important.Comment: 20 pages, 9 figures, 2 table
Impact of storage on sensory quality of blackcurrant juices prepared with or without enzymatic treatment at industrial scale
A multicenter randomized controlled trial of effect of medium-chain triglyceride dietary supplementation on epilepsy in dogs
Non-Gaussianities in two-field inflation
We study the bispectrum of the curvature perturbation on uniform energy
density hypersurfaces in models of inflation with two scalar fields evolving
simultaneously. In the case of a separable potential, it is possible to compute
the curvature perturbation up to second order in the perturbations, generated
on large scales due to the presence of non-adiabatic perturbations, by
employing the -formalism, in the slow-roll approximation. In this
case, we provide an analytic formula for the nonlinear parameter . We
apply this formula to double inflation with two massive fields, showing that it
does not generate significant non-Gaussianity; the nonlinear parameter at the
end of inflation is slow-roll suppressed. Finally, we develop a numerical
method for generic two-field models of inflation, which allows us to go beyond
the slow-roll approximation and confirms our analytic results for double
inflation.Comment: 29 pages, 6 figures. v2, comparison with previous estimates. v3, JCAP
version; Revisions based on Referee's comment, corrected typos, added few eqs
and refs, conclusions unchange
Beyond maternal death: improving the quality of maternal care through national studies of ‘near-miss’ maternal morbidity
BACKGROUND:
Studies of maternal mortality have been shown to result in important improvements to women’s health. It is now recognised that in countries such as the UK, where maternal deaths are rare, the study of near-miss severe maternal morbidity provides additional information to aid disease prevention, treatment and service provision.
OBJECTIVES:
To (1) estimate the incidence of specific near-miss morbidities; (2) assess the contribution of existing risk factors to incidence; (3) describe different interventions and their impact on outcomes and costs; (4) identify any groups in which outcomes differ; (5) investigate factors associated with maternal death; (6) compare an external confidential enquiry or a local review approach for investigating quality of care for affected women; and (7) assess the longer-term impacts.
METHODS:
Mixed quantitative and qualitative methods including primary national observational studies, database analyses, surveys and case studies overseen by a user advisory group.
SETTING:
Maternity units in all four countries of the UK.
PARTICIPANTS:
Women with near-miss maternal morbidities, their partners and comparison women without severe morbidity.
MAIN OUTCOME MEASURES:
The incidence, risk factors, management and outcomes of uterine rupture, placenta accreta, haemolysis, elevated liver enzymes and low platelets (HELLP) syndrome, severe sepsis, amniotic fluid embolism and pregnancy at advanced maternal age (≥ 48 years at completion of pregnancy); factors associated with progression from severe morbidity to death; associations between severe maternal morbidity and ethnicity and socioeconomic status; lessons for care identified by local and external review; economic evaluation of interventions for management of postpartum haemorrhage (PPH); women’s experiences of near-miss maternal morbidity; long-term outcomes; and models of maternity care commissioned through experience-led and standard approaches.
RESULTS:
Women and their partners reported long-term impacts of near-miss maternal morbidities on their physical and mental health. Older maternal age and caesarean delivery are associated with severe maternal morbidity in both current and future pregnancies. Antibiotic prescription for pregnant or postpartum women with suspected infection does not necessarily prevent progression to severe sepsis, which may be rapidly progressive. Delay in delivery, of up to 48 hours, may be safely undertaken in women with HELLP syndrome in whom there is no fetal compromise. Uterine compression sutures are a cost effective second-line therapy for PPH. Medical comorbidities are associated with a fivefold increase in the odds of maternal death from direct pregnancy complications. External reviews identified more specific clinical messages for care than local reviews. Experience-led commissioning may be used as a way to commission maternity services.
LIMITATIONS:
This programme used observational studies, some with limited sample size, and the possibility of uncontrolled confounding cannot be excluded.
CONCLUSIONS:
Implementation of the findings of this research could prevent both future severe pregnancy complications as well as improving the outcome of pregnancy for women. One of the clearest findings relates to the population of women with other medical and mental health problems in pregnancy and their risk of severe morbidity. Further research into models of pre-pregnancy, pregnancy and postnatal care is clearly needed
Fine Structure in the -Delayed Proton Decay of Ar
Low energy beta-delayed protons from Ar have been measured for the first time. The data reveal states, which, despite unfavourable barrier penetrability values, strongly decay to the first excited 2 state in S. The observation is discussed in terms of the standard shell model. A natural explanation is provided by the large spectroscopic amplitudes, involving and orbitals, as well as the =0 barrier penetrability, favouring the decay to the 2 state
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Developing European conservation and mitigation tools for pollination services: approaches of the STEP (Status and Trends of European Pollinators) project
Pollinating insects form a key component of European biodiversity, and provide a vital ecosystem service to crops and wild plants. There is growing evidence of declines in both wild and domesticated pollinators, and parallel declines in plants relying upon them. The STEP project (Status and Trends of European Pollinators, 2010-2015, www.stepproject.net) is documenting critical elements in the nature and extent of these declines, examining key functional traits associated with pollination deficits, and developing a Red List for some European pollinator groups. Together these activities are laying the groundwork for future pollinator monitoring programmes. STEP is also assessing the relative importance of potential drivers of pollinator declines, including climate change, habitat loss and fragmentation, agrochemicals, pathogens, alien species, light pollution, and their interactions. We are measuring the ecological and economic impacts of declining pollinator services and floral resources, including effects on wild plant populations, crop production and human nutrition. STEP is reviewing existing and potential mitigation options, and providing novel tests of their effectiveness across Europe. Our work is building upon existing and newly developed datasets and models, complemented by spatially-replicated campaigns of field research to fill gaps in current knowledge. Findings are being integrated into a policy-relevant framework to create evidence-based decision support tools. STEP is establishing communication links to a wide range of stakeholders across Europe and beyond, including policy makers, beekeepers, farmers, academics and the general public. Taken together, the STEP research programme aims to improve our understanding of the nature, causes, consequences and potential mitigation of declines in pollination services at local, national, continental and global scales
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