Research and Design of a Routing Protocol in Large-Scale Wireless Sensor Networks

无线传感器网络，作为全球未来十大技术之一，集成了传感器技术、嵌入式计算技术、分布式信息处理和自组织网技术，可实时感知、采集、处理、传输网络分布区域内的各种信息数据，在军事国防、生物医疗、环境监测、抢险救灾、防恐反恐、危险区域远程控制等领域具有十分广阔的应用前景。 本文研究分析了无线传感器网络的已有路由协议，并针对大规模的无线传感器网络设计了一种树状路由协议，它根据节点地址信息来形成路由，从而简化了复杂繁冗的路由表查找和维护，节省了不必要的开销，提高了路由效率，实现了快速有效的数据传输。 为支持此路由协议本文提出了一种自适应动态地址分配算——ADAR（AdaptiveDynamicAddre...As one of the ten high technologies in the future, wireless sensor network, which is the integration of micro-sensors, embedded computing, modern network and Ad Hoc technologies, can apperceive, collect, process and transmit various information data within the region. It can be used in military defense, biomedical, environmental monitoring, disaster relief, counter-terrorism, remote control of haz...学位：工学硕士院系专业：信息科学与技术学院通信工程系_通信与信息系统学号：2332007115216

Guided weapon template generation: a probabilistic approach

In this paper, we outline an approach for the generation of guided weapon safety templates via probabilistic means. This approach involves the calculation of a ground impact distribution database for each weapon via Monte Carlo simulations performed on a 'farm' of computers. A safety template specific to a user-defined firing envelope is then generated. The template is a probability density function of the ground impacts for the specified firing parameters. We are currently building a two-part system to provide this capability to the Australian Department of Defence for weapon test and evaluation purposes. The first part is a data preparation process that weapon experts can use to produce the weapon-specific ground impact distribution databases. The second part of the system is a software tool intended for operational users and range managers. This tool references the weapon database to generate a safety template for a specific firing envelope. We intend that the system be accepted for general use by the Department of Defence; hence, we are building it in accordance with departmental quality assurance requirements for complex aerospace systems

Guided weapon danger area generation: implementing a probabilistic approach

In this paper, we outline an approach for the generation of guided weapon danger area safety traces via probabilistic means. This approach involves the calculation of a ground impact distribution database for each weapon via Monte Carlo simulations performed on a ‘farm’ of computers. A safety trace specific to a user-defined firing envelope is then generated. The safety trace is a probability density function of the ground impacts for the specified firing parameters. We are currently building a two-part system to provide this capability to the Australian Department of Defence for weapon test and evaluation purposes. The first part is a data preparation process that weapon experts can use to produce the weapon-specific ground impact distribution databases. The second part of the system is a software tool intended for operational users and range managers. This tool references the weapon database to generate a Weapon Danger Area Safety Trace for a specific firing envelope. We intend that the system be accepted for general use by the Department of Defence; hence, we are building it in accordance with departmental quality assurance requirements for complex aerospace systems

Consumption of Energy Drinks among University Students in Eastern Croatia

The modern lifestyle today creates a certain pressure on people who are forced to adapt to such a way of living. Energy drinks (EDs), beverages containing certain stimulating ingredients, are increasingly being offered on the market. Given the unclear impact of EDs consumption on the health of the individual, the focus of this study was to determine the prevalence of EDs consumption among the student population at the University of Osijek (Eastern Croatia). The cross-sectional study via an anonymous questionnaire included 424 students, with an average age of 22.8 years. It was discovered that 52.4% of participants consume EDs. Males were significantly more likely to drink EDs than females (χ2-test; p = 0.006). They more frequently consume EDs six or more times per month (χ2-test; p = 0.045) as well as consume more EDs on one occasion (χ2-test; p 2-test; p = 0.024) as well as smokers in comparison to non-smokers (χ2-test; p = 0.034). In conclusion, the study proved the frequent consumption of EDs among Croatian university students consequently highlighting the need to raise awareness of the possible adverse effects of EDs consumption

ekoNET - Environmental Monitoring using Low-cost Sensors for Detecting Gases, Particulate Matter and Meteorological Parameters

This paper presents the environmental monitoring solution ekoNET, developed for a real-time monitoring of air pollution and other atmospheric condition parameters such as temperature, air pressure and humidity. The system is based on low-cost gas, PM and meteorological sensors providing cost-efficient, simple to deploy, use and maintain solution targeted for the usage within the Internet of Things domain of smart cities and smart enterprises. The paper gives an overview of the system architecture, encompassing the ekoNET device, back-end cloud infrastructure, data handling and visualization engine as well as the application-level components and modules. Furthermore, initial field trial data of twelve ekoNET devices is presented, enabling the overall system operation performance testing.International Conference on Innovative Mobile and Internet Services in Ubiquitous Computing., 8th International Conference on Innovative Mobile and Internet Services in Ubiquitous Computing (IMIS), Jul 02-04, 2014, Birmingham City Univ, Birmingham, Englan

A Functional Cancer Genomics Screen Identifies a Druggable Synthetic Lethal Interaction between MSH3 and PRKDC

Here, we use a large-scale cell line-based approach to identify cancer cell-specific mutations that are associated with DNA-dependent protein kinase catalytic subunit (DNA-PKcs) dependence. For this purpose, we profiled the mutational landscape across 1,319 cancer-associated genes of 67 distinct cell lines and identified numerous genes involved in homologous recombination-mediated DNA repair, including BRCA1, BRCA2, ATM, PAXIP, and RAD50, as being associated with non-oncogene addiction to DNA-PKcs. Mutations in the mismatch repair gene MSH3, which have been reported to occur recurrently in numerous human cancer entities, emerged as the most significant predictors of DNA-PKcs addiction. Concordantly, DNA-PKcs inhibition robustly induced apoptosis in MSH3 mutant cell lines in vitro and displayed remarkable single-agent efficacy against MSH3-mutant tumors in vivo. Thus, we here identify a therapeutically actionable synthetic lethal interaction between MSH3 and the non-homologous end joining kinase DNA-PKcs. Our observations recommend DNA-PKcs inhibition as a therapeutic concept for the treatment of human cancers displaying homologous recombination defects. SIGNIFICANCE: We associate mutations in the MSH3 gene, which are frequently detected in microsatellite-instable colon cancer (similar to 40%), with a therapeutic response to specific DNA-PKcs inhibitors. Because potent DNA-PKcs inhibitors are currently entering early clinical trials, we offer a novel opportunity to genetically stratify patients who may benefit from a DNA-PKcs-inhibitory therapy. (C) 2014 AACR

Management practices for postdural puncture headache in obstetrics: a prospective, international, cohort study

Background: Accidental dural puncture is an uncommon complication of epidural analgesia and can cause postdural puncture headache (PDPH). We aimed to describe management practices and outcomes after PDPH treated by epidural blood patch (EBP) or no EBP. Methods: Following ethics committee approval, patients who developed PDPH after accidental dural puncture were recruited from participating countries and divided into two groups, those receiving EBP or no EBP. Data registered included patient and procedure characteristics, headache symptoms and intensity, management practices, and complications. Follow-up was at 3 months. Results: A total of 1001 patients from 24 countries were included, of which 647 (64.6%) received an EBP and 354 (35.4%) did not receive an EBP (no-EBP). Higher initial headache intensity was associated with greater use of EBP, odds ratio 1.29 (95% confidence interval 1.19–1.41) per pain intensity unit increase. Headache intensity declined sharply at 4 h after EBP and 127 (19.3%) patients received a second EBP. On average, no or mild headache (numeric rating score≤3) was observed 7 days after diagnosis. Intracranial bleeding was diagnosed in three patients (0.46%), and backache, headache, and analgesic use were more common at 3 months in the EBP group. Conclusions: Management practices vary between countries, but EBP was more often used in patients with greater initial headache intensity. EBP reduced headache intensity quickly, but about 20% of patients needed a second EBP. After 7 days, most patients had no or mild headache. Backache, headache, and analgesic use were more common at 3 months in patients receiving an EBP

Management practices for postdural puncture headache in obstetrics: a prospective, international, cohort study

© 2020 British Journal of AnaesthesiaBackground: Accidental dural puncture is an uncommon complication of epidural analgesia and can cause postdural puncture headache (PDPH). We aimed to describe management practices and outcomes after PDPH treated by epidural blood patch (EBP) or no EBP. Methods: Following ethics committee approval, patients who developed PDPH after accidental dural puncture were recruited from participating countries and divided into two groups, those receiving EBP or no EBP. Data registered included patient and procedure characteristics, headache symptoms and intensity, management practices, and complications. Follow-up was at 3 months. Results: A total of 1001 patients from 24 countries were included, of which 647 (64.6%) received an EBP and 354 (35.4%) did not receive an EBP (no-EBP). Higher initial headache intensity was associated with greater use of EBP, odds ratio 1.29 (95% confidence interval 1.19–1.41) per pain intensity unit increase. Headache intensity declined sharply at 4 h after EBP and 127 (19.3%) patients received a second EBP. On average, no or mild headache (numeric rating score≤3) was observed 7 days after diagnosis. Intracranial bleeding was diagnosed in three patients (0.46%), and backache, headache, and analgesic use were more common at 3 months in the EBP group. Conclusions: Management practices vary between countries, but EBP was more often used in patients with greater initial headache intensity. EBP reduced headache intensity quickly, but about 20% of patients needed a second EBP. After 7 days, most patients had no or mild headache. Backache, headache, and analgesic use were more common at 3 months in patients receiving an EBP