139 research outputs found

    in front of me

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    Geographic Information System Data Analysis

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    Data was collected in order to further NASA Langley Research Center's Geographic Information System(GIS). Information on LaRC's communication, electrical, and facility configurations was collected. Existing data was corrected through verification, resulting in more accurate databases. In addition, Global Positioning System(GPS) points were used in order to accurately impose buildings on digitized images. Overall, this project will help the Imaging and CADD Technology Team (ICTT) prove GIS to be a valuable resource for LaRC

    Understanding the Uptown Triangle Neighborhood: Mapping Quality of Life Indicators in the Black Pearl

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    In the spring of 2015, University of New Orleans (UNO) students enrolled in the MURP 4081/5081 course-Applied Geographic Information Systems: Information Technology for the Planning Profession (also known as ‘Applied GIS’) led by Dr. Michelle Thompson. Since 2008 this course has provided students with a blended experience with learning the theory and receiving an introduction to spatial analysis using the Environmental Systems Research Institute (ESRI) ArcGIS software then applying this knowledge as GIS Analysts with a non-profit community partner. In the fall of 2014, Dr. Thompson competed to have this course designated as the inaugural Department of Planning and Urban Studies (PLUS) service learning course. By January 2015, Thompson developed a scope of services and formed a partnership with the Uptown Triangle Neighborhood Association (UTNA) to evaluate Quality of Life Indicators limited to the evaluation of property, road, and storm drain conditions. The Uptown Triangle Neighborhood (UTN), which was formerly known as the ‘Black Pearl’, is a triangular shaped neighborhood and is bounded by Street Charles Avenue, Broadway Avenue, and Leake Avenue. Prior to the UTNA study, Graham Hayes – UTNA Board Member, UT resident, former WhoData Intern and Bachelor of Science in Urban Studies Program’14 graduate, had developed a series of datasets and crowdsourced data through resident and volunteer activities from spring to early fall 2014. The GIS Mapping Analysts collected primary and integrated secondary data to provide the results of their study in this report. Within the same project, a separate team of novice GIS Programming Analysts developed, tested with the GIS Mapping Analysts and deployed a web-enabled data collection application known as the ‘WhoData Map App.’ The goal of this project and the goal of the client, is to create a tool that will empower members of the neighborhood to advocate community involvement in decision making for the Uptown Triangle Neighborhood. It will also provide a strategic resource for members of the community to evaluate future conditions that may impact the quality of life for those that live there

    Concert recording 2016-04-19a

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    [Track 01]. Canzon duodecimi toni / Giovanni Gabrieli -- [Track 02]. Divertissement. Andante - allegro ; [Track 03]. Allegro vivace ; [Track 04]. Andante / Emile Bernard -- [Track 05]. March for military music in F major, Yorck march WoO 18 / Ludwig van Beethoven -- [Track 06]. Sept danses. Le jeu de la poupée ; [Track 07]. Funérailles de la poupée ; [Track 08]. La présentation des petits amis ; [Track 09]. Variation de Paul ; [Track 10]. Pas de deux entre Sophie et Paul ; [Track 11]. La goûter ; [Track 12]. Danse des filets à papillons / Jean Françaix

    Proximal tibial osteophytes and their relationship with the height of the tibial spines of the intercondylar eminence: paleopathological study

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    Tibial spiking (i.e., spurring of tibial spines), eburnation, and osteophytes are considered features of osteoarthritis. This investigation employed direct inspection of the medial and lateral tibial plateaus in paleopathological specimens to analyze the frequency and morphological features of osteoarthritis and to define any relationship between the size of osteophytes and that of the intercondylar tibial spines. A total of 35 tibial bone specimens were evaluated for the degree of osteoarthritis and presence of eburnation. Each plateau was also divided into four quadrants and the presence and size of bone outgrowths were recorded in each quadrant. The “medial/lateral tibial intercondylar spine index” for each specimen was calculated as follows: (medial/lateral intercondylar tibial spine height)/(anteroposterior width of the superior tibial surface). The relationships between medial and lateral tibial height indexes with the degree of osteoarthritis were then tested. Osteophytes were observed more frequently in the anterior quadrants of both tibial plateaus than in the posterior quadrants (29 vs 16 for the medial tibial plateau [p = 0.01] and 28 vs 20 for the lateral tibial plateau [p = 0.04]). Eburnation was seen more frequently in the posterior regions of both tibial plateaus than in the anterior regions (17 vs 5, p < 0.01). In specimens with no signs of osteoarthritis the lateral intercondylar tibial index was significantly lower than that in specimens with some degree of osteoarthritis (p = 0.02). The medial intercondylar tibial index of the specimens with no signs of osteoarthritis was not significantly different from that of the specimens with some degree of osteoarthritis (p = 0.45). There was a positive correlation between the lateral spine height index and the overall grading of osteoarthritis, (r = 0.6, p < 0.01). In the anteromedial and posteromedial quadrants of the lateral tibial plateau, the association between the lateral intercondylar tibial spine index and the grade of osteophytes was 0.5 (p < 0.01) and 0.7 (p < 0.01) respectively. Spiking of the lateral tibial intercondylar spine is associated with osteophyte formation and osteoarthritis. Eburnation occurs mainly in the posterior parts of the tibial plateaus while osteophytes arise mainly in the anterior parts. These findings suggest that stresses occurring in the flexed knee may contribute to many of the morphological abnormalities of osteoarthritis

    Concert recording 2016-04-03

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    [Track 01]. Fanfare pour précéder \u27La Péri\u27 / Paul Dukas -- [Track 02]. French dances revisted. I ; [Track 03]. II ; [Track 04]. III ; [Track 05]. IV ; [Track 06]. V ; [Track 07]. VI / Adam Gorb -- [Track 08]. Danses sacrée et profane / Claude Debussy -- [Track 09]. Dance mix / Rob Smith

    Towards a more universal life detection strategy

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    This white paper argues for a more universal approach to life detection. We recommend that life detection missions focus on looking for signatures of life deemed to be shared by all possible types of life, independent of their specific biochemistries, rather than looking for signatures of life that could arguably be specific to Terran-life

    Biochemical properties and base excision repair complex formation of apurinic/apyrimidinic endonuclease from Pyrococcus furiosus

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    Apurinic/apyrimidinic (AP) sites are the most frequently found mutagenic lesions in DNA, and they arise mainly from spontaneous base loss or modified base removal by damage-specific DNA glycosylases. AP sites are cleaved by AP endonucleases, and the resultant gaps in the DNA are repaired by DNA polymerase/DNA ligase reactions. We identified the gene product that is responsible for the AP endonuclease activity in the hyperthermophilic euryarchaeon, Pyrococcus furiosus. Furthermore, we detected the physical interaction between P. furiosus AP endonuclease (PfuAPE) and proliferating cell nuclear antigen (PCNA; PfuPCNA) by a pull-down assay and a surface plasmon resonance analysis. Interestingly, the associated 3′–5′ exonuclease activity, but not the AP endonuclease activity, of PfuAPE was stimulated by PfuPCNA. Immunoprecipitation experiments using the P. furiosus cell extracts supported the interaction between PfuAPE and PfuPCNA in the cells. This is the first report describing the physical and functional interactions between an archaeal AP endonuclease and PCNA. We also detected the ternary complex of PfuPCNA, PfuAPE and Pfu uracil-DNA glycosylase. This complex probably functions to enhance the repair of uracil-containing DNA in P. furiosus cells
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