618 research outputs found
Univocity, Duality, and Ideal Genesis: Deleuze and Plato
In this essay, we consider the formal and ontological implications of one specific and intensely contested dialectical context from which Deleuzeās thinking about structural ideal genesis visibly arises. This is the formal/ontological dualism between the principles, į¼ĻĻĪ±ĪÆ, of the One (į¼Ī½) and the Indefinite/Unlimited Dyad (į¼ĻĻĪ¹ĻĻĪæĻ Ī“Ļ
Ī¬Ļ), which is arguably the culminating achievement of the later Platoās development of a mathematical dialectic.3 Following commentators including Lautman, Oskar Becker, and Kenneth M. Sayre, we argue that the duality of the One and the Indefinite Dyad provides, in the later Plato, a unitary theoretical formalism accounting, by means of an iterated mixing without synthesis, for the structural origin and genesis of both supersensible Ideas and the sensible particulars which participate in them. As these commentators also argue, this duality furthermore provides a maximally general answer to the problem of temporal becoming that runs through Platoās corpus: that of the relationship of the flux of sensory experiences to the fixity and order of what is thinkable in itself. Additionally, it provides a basis for understanding some of the famously puzzling claims about forms, numbers, and the principled genesis of both attributed to Plato by Aristotle in the Metaphysics, and plausibly underlies the late Platoās deep considerations of the structural paradoxes of temporal change and becoming in the Parmenides, the Sophist, and the Philebus. After extracting this structure of duality and developing some of its formal, ontological, and metalogical features, we consider some of its specific implications for a thinking of time and ideality that follows Deleuze in a formally unitary genetic understanding of structural difference. These implications of Platoās duality include not only those of the constitution of specific theoretical domains and problematics, but also implicate the reflexive problematic of the ideal determinants of the form of a unitary theory as such. We argue that the consequences of the underlying duality on the level of content are ultimately such as to raise, on the level of form, the broader reflexive problem of the basis for its own formal or meta-theoretical employment. We conclude by arguing for the decisive and substantive presence of a proper āPlatonismā of the Idea in Deleuze, and weighing the potential for a substantive recuperation of Platoās duality in the context of a dialectical affirmation of what Deleuze recognizes as the āonlyā ontological proposition that has ever been uttered. This is the proposition of the univocity of Being, whereby ābeing is said in the same sense, everywhere and always,ā but is said (both problematically and decisively) of difference itself
Technical Excellence and Communication: The Cornerstones for Successful Safety and Mission Assurance Programs
The paper describes the role of technical excellence and communication in the development and maintenance of safety and mission assurance programs. The Marshall Space Flight Center (MSFC) Safety and Mission Assurance (S&MA) organization is used to illustrate philosophies and techniques that strengthen safety and mission assurance efforts and that contribute to healthy and effective organizational cultures. The events and conditions leading to the development of the MSFC S&MA organization are reviewed. Historic issues and concerns are identified. The adverse effects of resource limitations and risk assessment roles are discussed. The structure and functions of the core safety, reliability, and quality assurance functions are presented. The current organization s mission and vision commitments serve as the starting points for the description of the current organization. The goals and objectives are presented that address the criticisms of the predecessor organizations. Additional improvements are presented that address the development of technical excellence and the steps taken to improve communication within the Center, with program customers, and with other Agency S&MA organizations
Effectiveness of mozart music therapy on post-operative pain among children undergone surgery at selected hospital, Chennai
A study to assess the effectiveness of Mozart music therapy on post-operative pain among children undergone surgery at Selected Hospital, Chennai.
OBJECTIVES OF THE STUDY
1. To assess the pre-test level of post-operative pain among children in both experimental and control group.
2. To assess the post-test level of post-operative pain among children in both experimental and control group.
3. To assess the effectiveness of Mozart Music Therapy on post operative pain among children in both experimental and control group.
METHODS
A true experimental design was adopted for this study. A review
of literature was done on studies related to benefits of music on post
operative pain, effect of music therapy on pain, benefits of Mozart
music and Nursing care and pain management. The study was conducted in
Chettinad Hospital, Kelambakkam, Chennai. The tool used was Wong-
Baker FACES Pain Rating Scale. The sample size for this study was 60
postoperative children (30 in experimental; 30 in control group) selected
using simple random sampling technique with lottery method. The
intervention given in this study was Mozart Music for 3 consecutive
days. Pre test of pain in experimental and control group was assessed
using Wong-Baker pain scale. Each hospitalized children after surgery
on the first postoperative day was given Mozart music therapy at the
duration of 10 minutes for 3 consecutive days. The post test of pain in
experimental and control group were assessed on the third day using
Wong-Baker pain scale. The data was analysed and interpreted based on
the objectives using descriptive and inferential statistics.
MAJOR FINDINGS OF THE STUDY
The study findings revealed that the frequency and percentage
distribution of pre-test level of pain in experimental group, 30(100%) were in
moderate pain level & none of them were in no pain level, mild pain level &
severe pain level. In control group, 30(100%) were in moderate pain level.
The frequency and percentage distribution of post-test level of pain in
experimental group, 8(26.67%) were in moderate pain level & 22(73.33%)
were in mild pain level. In control group, 30(100%) were in moderate pain
level. The study findings also revealed that the pre-test mean and standard
deviation were 5.43 and 0.50 respectively and in the post-test mean and
standard deviation were 3.10 and 1.06 respectively. The findings also
revealed that there was a significant association with one selected
demographic variable.
Thus it is proved that after the administration of Mozart Music Therapy
the post operative pain was considerably reduced among children who
underwent surgery and this clearly indicates that Mozart Music therapy was
found to be effective in reducing the pain among children in the experimental
group.
CONCLUSION
Mozart music therapy is an effective intervention in reducing
the pain among children who has underwent surgery. From a nursing
perspective, this intervention provides a challenge and an opportunity for
nurses to blend alternative therapies in managing postoperative pain among
children. The study is focused on Mozart music as it appears to be an
effective non-invasive, non-pharmacological and relatively cheap intervention
for postoperative pain management, and this measure will be considered as a
diversional strategy to reduce pain experienced by children who have
underwent surgery.
4. To associate the post-test level of post-operative pain among children in experimental group with the selected demographic variables
Evaluation of SMAP Freeze/Thaw Retrieval Accuracy at Core Validation Sites in the Contiguous United States
Seasonal freeze-thaw (FT) impacts much of the northern hemisphere and is an important control on its water, energy, and carbon cycle. Although FT in natural environments extends south of 45Ā°N, FT studies using the L-band have so far been restricted to boreal or greater latitudes. This study addresses this gap by applying a seasonal threshold algorithm to Soil Moisture Active Passive (SMAP) data (L3_SM_P) to obtain a FT product south of 45Ā°N (āSMAP FTā), which is then evaluated at SMAP core validation sites (CVS) located in the contiguous United States (CONUS). SMAP landscape FT retrievals are usually in good agreement with 0ā5 cm soil temperature at SMAP grids containing CVS stations (\u3e70%). The accuracy could be further improved by taking into account specific overpass time (PM), the grid-specific seasonal scaling factor, the data aggregation method, and the sampling error. Annual SMAP FT extent maps compared to modeled soil temperatures derived from the Goddard Earth Observing System Model Version 5 (GEOS-5) show that seasonal FT in CONUS extends to latitudes of about 35ā40Ā°N, and that FT varies substantially in space and by year. In general, spatial and temporal trends between SMAP and modeled FT were similar
Developments at the Advanced Design Technologies Testbed
A report presents background and historical information, as of August 1998, on the Advanced Design Technologies Testbed (ADTT) at Ames Research Center. The ADTT is characterized as an activity initiated to facilitate improvements in aerospace design processes; provide a proving ground for product-development methods and computational software and hardware; develop bridging methods, software, and hardware that can facilitate integrated solutions to design problems; and disseminate lessons learned to the aerospace and information technology communities
The Ī“āopioid receptor positive allosteric modulator BMS 986187 is a Gāproteinābiased allosteric agonist
Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/149355/1/bph14602.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/149355/2/bph14602_am.pd
60 Validated Planets from K2 Campaigns 5-8
We present a uniform analysis of 155 candidates from the second year of
NASA's mission (Campaigns 5-8), yielding 60 statistically validated
planets spanning a range of properties, with median values of = 2.5
, = 7.1 d, = 811 K, and = 11.3 mag. The
sample includes 24 planets in 11 multi-planetary systems, as well as 18 false
positives, and 77 remaining planet candidates. Of particular interest are 18
planets smaller than 2 , five orbiting stars brighter than = 10
mag, and a system of four small planets orbiting the solar-type star EPIC
212157262. We compute planetary transit parameters and false positive
probabilities using a robust statistical framework and present a complete
analysis incorporating the results of an intensive campaign of high resolution
imaging and spectroscopic observations. This work brings the yield to over
360 planets, and by extrapolation we expect that will have discovered
600 planets before the expected depletion of its on-board fuel in late
2018.Comment: 33 pages, 13 figures, 5 tables, accepted for publication in A
TOI-2196 b: Rare planet in the hot Neptune desert transiting a G-type star
The hot Neptune desert is a region hosting a small number of short-period Neptunes in the radius-instellation diagram. Highly irradiated planets are usually either small (R ā² 2 Rā) and rocky or they are gas giants with radii of ā³1 RJ. Here, we report on the intermediate-sized planet TOI-2196 b (TIC 372172128.01) on a 1.2 day orbit around a G-type star (V = 12.0, [Fe/H] = 0.14 dex) discovered by the Transiting Exoplanet Survey Satellite in sector 27. We collected 41 radial velocity measurements with the HARPS spectrograph to confirm the planetary nature of the transit signal and to determine the mass. The radius of TOI-2196 b is 3.51 Ā± 0.15 Rā, which, combined with the mass of 26.0 Ā± 1.3 Mā, results in a bulk density of 3.31ā0.43+0.51 g cmā3. Hence, the radius implies that this planet is a sub-Neptune, although the density is twice than that of Neptune. A significant trend in the HARPS radial velocity measurements points to the presence of a distant companion with a lower limit on the period and mass of 220 days and 0.65 MJ, respectively, assuming zero eccentricity. The short period of planet b implies a high equilibrium temperature of 1860 Ā± 20 K, for zero albedo and isotropic emission. This places the planet in the hot Neptune desert, joining a group of very few planets in this parameter space discovered in recent years. These planets suggest that the hot Neptune desert may be divided in two parts for planets with equilibrium temperatures of ā³1800 K: a hot sub-Neptune desert devoid of planets with radii of ā 1.8ā3 Rā and a sub-Jovian desert for radii of ā5ā12 Rā. More planets in this parameter space are needed to further investigate this finding. Planetary interior structure models of TOI-2196 b are consistent with a H/He atmosphere mass fraction between 0.4% and 3%, with a mean value of 0.7% on top of a rocky interior. We estimated the amount of mass this planet might have lost at a young age and we find that while the mass loss could have been significant, the planet had not changed in terms of character: it was born as a small volatile-rich planet and it remains one at present
K2 Discovers a Busy Bee: An Unusual Transiting Neptune Found in the Beehive Cluster
Open clusters have been the focus of several exoplanet surveys but only a few
planets have so far been discovered. The \emph{Kepler} spacecraft revealed an
abundance of small planets around small, cool stars, therefore, such cluster
members are prime targets for exoplanet transit searches. Kepler's new mission,
K2, is targeting several open clusters and star-forming regions around the
ecliptic to search for transiting planets around their low-mass constituents.
Here, we report the discovery of the first transiting planet in the
intermediate-age (800 Myr) Beehive cluster (Praesepe). K2-95 is a faint
() dwarf from K2's Campaign 5
with an effective temperature of , approximately
solar metallicity and a radius of . We
detected a transiting planet with a radius of and an orbital period of 10.134 days. We combined photometry,
medium/high-resolution spectroscopy, adaptive optics/speckle imaging and
archival survey images to rule out any false positive detection scenarios,
validate the planet, and further characterize the system. The planet's radius
is very unusual as M-dwarf field stars rarely have Neptune-sized transiting
planets. The comparatively large radius of K2-95b is consistent with the other
recently discovered cluster planets K2-25b (Hyades) and K2-33b (Upper
Scorpius), indicating systematic differences in their evolutionary states or
formation. These discoveries from K2 provide a snapshot of planet formation and
evolution in cluster environments and thus make excellent laboratories to test
differences between field-star and cluster planet populations.Comment: 14 pages, 8 figues. Accepted for publication in A
Sequential single doses of cisapride, erythromycin, and metoclopramide in critically ill patients intolerant to enteral nutrition: A randomized, placebo-controlled, crossover study
Objective: To evaluate the comparative efficacy of enteral cisapride, metoclopramide, erythromycin, and placebo for promoting gastric emptying in critically ill patients with intolerance to gastric enteral nutrition (EN).
Design: A randomized, crossover study.
Setting: Adult medical intensive care unit at a university-affiliated private hospital and trauma intensive care unit at a university teaching hospital.
Patients: Ten adult, critically ill, mechanically ventilated patients not tolerating a fiber-containing EN product defined as a single aspirated gastric residual volume \u3e150 mL or two aspirated gastric residual volumes \u3e120 mL during a 12-hr period.
Interventions: Patients received 10 mg of cisapride, 200 mg of erythromycin ethylsuccinate, 10 mg of metoclopramide, and placebo as 20 mL of sterile water every 12 hrs over 48 hrs. Acetaminophen solution (1000 mg) was administered concurrently. Gastric residual volumes were assessed, and plasma acetaminophen concentrations were serially determined by TDx between 0 and 12 hrs to evaluate gastric emptying.
Measurements and Main Results: Gastric residual volumes during the study were not significantly different between agents. No differences in area under the concentration vs. time curve or elimination rate constant were identified between agents. Metoclopramide and cisapride had a significantly shorter mean residence time of absorption than erythromycin (6.3 Ā± 4.5 [SEM] mins and 10.9 Ā± 5.8 vs. 30.1 Ā± 4.5 mins, respectively [p \u3c .05]). Metoclopramide (9.7 Ā± 15.3 mins) had a significantly shorter time to peak concentration compared with erythromycin and placebo (60.7 Ā± 8.1 and 50.9 Ā± 13.5 mins, respectively [p \u3c .05]). The time to onset of absorption was significantly shorter for metoclopramide vs. cisapride (5.7 Ā± 4.5 vs. 22.9 Ā± 5.7 mins [p \u3c .05]).
Conclusion: In critically ill patients intolerant to EN, single enteral doses of metoclopramide or cisapride are effective for promoting gastric emptying in critically ill patients with gastric motility dysfunction. Additionally, metoclopramide may provide a quicker onset than cisapride
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