Sideload vanes for fluid pump

A fluid pump assembly includes a rotatable component that can be rotated about an axis and a static vane assembly located adjacent to the rotatable component. The static vane assembly includes a circumferential surface axially spaced from the rotatable component, and one or more vanes extending from the circumferential surface toward the rotatable component. The one or more vanes are configured to produce a radial load on the rotatable component when the rotatable component is rotating about the axis and a fluid is present between the static vane assembly and the rotatable component

The Prevalence of Rapid Weight Gain in Infancy Differs by the Growth Reference and Age Interval Used for Evaluation

Background: Infant rapid weight gain (RWG) may predict subsequent obesity, but there are inconsistencies in the growth references and age intervals used for assessment. Methods: This study evaluated whether the prevalence of RWG (an increase of \u3e0.67 in weight-for-age z-score) differed by growth reference (2006 WHO standards vs 2000 CDC references) and age interval of assessment (0–3, 0–6, 6–12 and 0–12 months). Pooled data from singleton term infants from two observational studies on maternal mood disorders during pregnancy were used (n = 161). Differences in RWG prevalence by growth reference and age interval were tested using Cochran’s Q and McNemar’s tests. Results: The CDC reference produced a higher RWG prevalence (14% of infants additionally categorized as RWG, p \u3c 0.0001) within the 0–3 month age interval compared to the WHO standards; this pattern was reversed for the 6–12 and 0–12 month intervals. RWG prevalence did not differ across age interval within the WHO standards, but did differ with the CDC references (range: 22% for 0–3 months to 4.2% for 6–12 months, p \u3c 0.0001). Conclusions: Caution is advised when comparing studies with different criteria for RWG. Future studies should use the 2006 WHO standards and a consistent age interval of evaluation

Loss of basal forebrain p75\u3csup\u3eNTR\u3c/sup\u3e immunoreactivity in subjects with mild cognitive impairment and Alzheimer\u27s disease

The long-held belief that degeneration of the cholinergic basal forebrain was central to Alzheimer\u27s disease (AD) pathogenesis and occurred early in the disease process has been questioned recently. In this regard, changes in some cholinergic basal forebrain (CBF) markers (e.g. the high affinity trkA receptor) but not others (e.g., cortical choline acetyltransferase [ChAT] activity, the number of ChAT and vesicular acetylcholine transporter-immunoreactive neurons) suggest specific phenotypic changes, but not frank neuronal degeneration, early in the disease process. The present study examined the expression of the low affinity p75 neurotrophin receptor (p75NTR), an excellent marker of CBF neurons, in postmortem tissue derived from clinically well-characterized individuals who have been classified as having no cognitive impairment (NCI), mild cognitive impairment (MCI), and mild AD. Relative to NCI individuals, a significant and similar reduction in the number of nucleus basalis p75NTR-immunoreactive neurons was seen in individuals with MCI (38%) and mild AD (43%). The number of p75NTR-immunoreactive nucleus basalis neurons was significantly correlated with performance on the Mini-Mental State Exam, a Global Cognitive Test score, as well as some individual tests of working memory and attention. These data, together with previous reports, support the concept that phenotypic changes, but not frank neuronal degeneration, occur early in cognitive decline. Although there was no difference in p75NTR CBF cell reduction between MCI and AD, it remains to be determined whether these findings lend support to the hypothesis that MCI is a prodromal stage of AD. © 2002 Wiley-Liss, Inc