2,111 research outputs found

    Light Quark Resonances in pbar p Annihilations at 5.2 GeV/c

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    Data from the Fermilab E835 experiment have been used to study the reaction pbar p -> eta eta pi0 at 5.2 GeV/c. A sample of 22 million six photons events has been analyzed to construct the Dalitz plot containing ~80k eta eta pi0 events. A partial wave analysis of the data has been done. Six f_J-states decaying into eta eta and five a_J-states decaying into eta pi0 are identified in the mass region ~1.3 and 2.4 GeV, and their masses, widths and spins are determined by maximum likelihood analysis of the data. Two f_0 states are identified with the popular candidates for the lightest scalar glueball, f_0(1500) and f_0(1710).Comment: 7 pages, 6 figure

    Cardiovascular and cerebrovascular risk factors and events associated with second-generation antipsychotic compared to antidepressant use in a non-elderly adult sample: results from a claims-based inception cohort study

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    This is a study of the metabolic and distal cardiovascular/cerebrovascular outcomes associated with the use of second-generation antipsychotics (SGAs) compared to antidepressants (ADs) in adults aged 18-65 years, based on data from Thomson Reuters MarketScan (R) Research Databases 2006-2010, a commercial U.S. claims database. Interventions included clinicians\u27 choice treatment with SGAs (allowing any comedications) versus ADs (not allowing SGAs). The primary outcomes of interest were time to inpatient or outpatient claims for the following diagnoses within one year of SGA or AD discontinuation: hypertension, ischemic and hypertensive heart disease, cerebrovascular disease, diabetes mellitus, hyperlipidemia, and obesity. Secondary outcomes included the same diagnoses at last follow-up time point, i.e., not censoring observations at 365 days after SGA or AD discontinuation. Cox regression models, adjusted for age, gender, diagnosis of schizophrenia and mood disorders, and number of medical comorbidities, were run. Among 284,234 individuals, those within one year of exposure to SGAs versus ADs showed a higher risk of essential hypertension (adjusted hazard ratio, AHR=1.16, 95% CI: 1.12-1.21,

    Cardiovascular risk in rheumatoid arthritis versus osteoarthritis: acute phase response related decreased insulin sensitivity and high-density lipoprotein cholesterol as well as clustering of metabolic syndrome features in rheumatoid arthritis

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    Rheumatoid arthritis (RA) patients experience a markedly increased frequency of cardiovascular disease. We evaluated cardiovascular risk profiles in 79 RA patients and in 39 age-matched and sex-matched osteoarthritis (OA) patients. Laboratory tests comprised ultrasensitive C-reactive protein (CRP) and fasting lipids. Insulin sensitivity (IS) was determined by the Quantitative Insulin Sensitivity Check Index (QUICKI) in all OA patients and in 39 of the RA patients. Ten RA patients were on glucocorticoids. RA patients exercised more frequently than OA patients (χ(2) = 3.9, P < 0.05). Nine RA patients and one OA patient had diabetes (χ(2) = 4.5, P < 0.05). The median CRP, the mean QUICKI and the mean high-density lipoprotein (HDL) cholesterol were 9 mg/l (range, 0.5–395 mg/l), 0.344 (95% confidence interval [CI], 0.332–0.355) and 1.40 mmol/l (95% CI, 1.30–1.49 mmol/l) in RA patients, respectively, as compared with 2.7 mg/l (range, 0.3–15.9 mg/l), 0.369 (95% CI, 0.356–0.383) and 1.68 mmol/l (95% CI, 1.50–1.85 mmol/l) in OA patients. Each of these differences was significant (P < 0.05). After controlling for the CRP, the QUICKI was similar in RA and OA patients (P = 0.07), while the differences in HDL cholesterol were attenuated but still significant (P = 0.03). The CRP correlated with IS, while IS was associated with high HDL cholesterol and low triglycerides in RA patients and not in OA patients. A high CRP (≥ 8 mg/l) was associated with hypertension (χ(2) = 7.4, P < 0.05) in RA patients. RA glucocorticoid and nonglucocorticoid users did not differ in IS and lipids (P > 0.05). Excess cardiovascular risk in RA patients as compared with OA patients includes the presence of decreased IS and HDL cholesterol in RA patients. The latter is only partially attributable to the acute phase response. The CRP, IS, HDL cholesterol, triglycerides and hypertension are inter-related in RA patients, whereas none of these relationships were found in OA patients

    Hyperlipidaemia, obesity and drug misuse in a diabetic clinic

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    A study of middle-aged and elderly patients attending a diabetic clinic has revealed a disturbing state of affairs. Hyperlipidaemia and obesity were very common but little attention was paid to implementing appropriate dietary regimens. Management was largely confined to the control of hyperglycaemia by using oral hypoglycaemic agents, especially combinations of sulphonylureas and diguanides. This situation is deplored. Firstly, it ignores the correction of factors which are as important, if not more so, than hyperglycaemia, in regard to the development of the most lethal complication of maturity-onset diabetes, namely occlusive atherosclerosis. Secondly, it substitutes for dietary therapy, which is physiological, treatment by drugs which are potentially harmful. It is probable that a similar situation obtains in many other diabetic clinics.S. Afr. Med. J., 48, 277 (1974)

    Integrating psychosocial and WASH school interventions to build disaster resilience

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    This paper reviews the key disaster risk management (DRM) frameworks used for protecting children's wellbeing in disaster settings and identifies a lack of consideration for (1) psychosocial and (2) water, sanitation and hygiene (WASH) needs. It also demonstrates that these two domains are meaningfully linked, as access to adequate WASH provision may protect psychosocial wellbeing and promote community resilience. As support in both domains is vitally important to children's wellbeing, these gaps warrant immediate attention. Schools are uniquely situated to support these needs as part of disaster risk management and resilience building. Therefore, we consider the ASEAN Common Framework for Comprehensive School Safety (ACFCSS), which is an adaptation of the Comprehensive School Safety Framework (CSS) implemented in schools across the ASEAN region. While the CSS explicitly considers WASH, it only briefly considers psychosocial support; the ACFCCS lacks consideration of both domains. We argue revisions of the ACFCSS should prioritise the inclusion of psychosocial and WASH support and consider the role of schools beyond their capacity as educational institutions. We present an adaptation of ACFCSS with an additional framework pillar to guide this revision. Overall, we advocate for an integrated approach to DRM in schools based on an evidence-based, interdisciplinary perspective. We provide a series of evidence-based recommendations for DRM frameworks to consider, especially for those that intend to safeguard the wellbeing of children

    Tunable Conductivity and Conduction Mechanism in a UV light activated electronic conductor

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    A tunable conductivity has been achieved by controllable substitution of a novel UV light activated electronic conductor. The transparent conducting oxide system H-doped Ca12-xMgxAl14O33 (x = 0; 0.1; 0.3; 0.5; 0.8; 1.0) presents a conductivity that is strongly dependent on the substitution level and temperature. Four-point dc-conductivity decreases with x from 0.26 S/cm (x = 0) to 0.106 S/cm (x = 1) at room temperature. At each composition the conductivity increases (reversibly with temperature) until a decomposition temperature is reached; above this value, the conductivity drops dramatically due to hydrogen recombination and loss. The observed conductivity behavior is consistent with the predictions of our first principles density functional calculations for the Mg-substituted system with x=0, 1 and 2. The Seebeck coefficient is essentially composition- and temperature-independent, the later suggesting the existence of an activated mobility associated with small polaron conduction. The optical gap measured remains constant near 2.6 eV while transparency increases with the substitution level, concomitant with a decrease in carrier content.Comment: Submitted for publicatio

    The Color Dipole Picture of low-x DIS: Model-Independent and Model-Dependent Results

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    We present a detailed examination of the color-dipole picture (CDP) of low-xx deep inelastic scattering. We discriminate model-independent results, not depending on a specific parameterization of the dipole cross section, from model-dependent ones. The model-independent results include the ratio of the longitudinal to the transverse photoabsorption cross section at large Q2Q^2, or equivalently the ratio of the longitudinal to the unpolarized proton structure function, FL(x,Q2)=0.27F2(x,Q2)F_L (x,Q^2)=0.27 F_2 (x, Q^2), as well as the low-xx scaling behavior of the total photoabsorption cross section σγp(W2,Q2)=σγp(η(W2,Q2))\sigma_{\gamma^*p} (W^2, Q^2)=\sigma_{\gamma^*p} (\eta (W^2, Q^2)) as log(1/η(W2,Q2))\log (1 / \eta (W^2, Q^2)) for η(W2,Q2)<1\eta (W^2, Q^2) <1, and as 1/η(W2,Q2)1/\eta (W^2, Q^2) for η(W2,Q2)1\eta (W^2, Q^2) \gg 1. Here, η(W2,Q2)\eta (W^2, Q^2) denotes the low-xx scaling variable, η(W2,Q2)=(Q2+m02)/Λsat2(W2)\eta (W^2, Q^2)=(Q^2 + m^2_0) / \Lambda^2_{sat} (W^2) with Λsat2(W2)\Lambda^2_{sat} (W^2) being the saturation scale. The model-independent analysis also implies limW2,Q2fixedσγp(W2,Q2)/σγp(W2)1\lim\limits_{W^2\rightarrow\infty, Q^2 {\rm fixed}} \sigma_{\gamma^*p} (W^2, Q^2) / \sigma_{\gamma p} (W^2) \rightarrow 1 at any Q2Q^2 for asymptotically large energy, WW. Consistency with pQCD evolution determines the underlying gluon distribution and the numerical value of C2=0.29C_2 = 0.29 in the expression for the saturation scale, Λ2(W2)(W2)C2\Lambda^2 (W^2) \sim (W^2)^{C_2}. In the model-dependent analysis, by restricting the mass of the actively contributing qqˉq \bar q fluctuations by an energy-dependent upper bound, we extend the validity of the color-dipole picture to xQ2/W20.1x \cong Q^2 / W^2 \le 0.1. The theoretical results agree with the world data on DIS for 0.036GeV2Q2316GeV20.036 {\rm GeV}^2 \le Q^2 \le 316 {\rm GeV}^2.Comment: 77 pages, 30 figure

    Identifying Local and Centralized Mental Health ServicesThe Development of a New Categorizing Variable

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    The challenges of mental health and substance abuse services (MHS) require shifting of the balance of resources from institutional care to community care. In order to track progress, an instrument that can describe these attributes of MHS is needed. We created a coding variable in the European Service Mapping Schedule-Revised (ESMS-R) mapping tool using a modified Delphi panel that classified MHS into centralized, local services with gatekeeping and local services without gatekeeping. For feasibility and validity, we tested the variable on a dataset comprising MHS in Southern Finland, covering a population of 2.3 million people. There were differences in the characteristics of services between our study regions. In our data, 41% were classified as centralized, 37% as local without gatekeeping and 22% as local services with gatekeeping. The proportion of resources allocated to local services varied from 20% to 43%. Reclassifying ESMS-R is an easy way to compare the important local vs. centralized balance of MHS systems globally, where such data exists. Further international studies comparing systems and validating this approach are needed.Peer reviewe
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