Movement Analysis Could Help in the Assessment of Chronic Low Back Pain Patients: Results from a Preliminary Explorative Study

Introduction: This study aimed to assess the reliability of a qualitative scoring system based on the movement analysis of the spine in different populations and after usual care rehabilitative intervention. If proven true, the results could further future research development in quantitative indexes, leading to a possible subclassification of chronic low back pain (cLBP). Methods: This was a preliminary exploratory observational study. Data of an optoelectronic spine movement analysis from a pathological population (cLBP population, 5 male, 5 female, age 58 ± 16 years) were compared to young healthy participants (5M, 5F, age 22 ± 1) and were analysed via a new qualitative score of the pattern of movement. Internal consistency was calculated. Two independent assessors (experienced and inexperienced) assessed the blinded data, and we calculated inter- and intrarater reliability. We performed an analysis for cLBP pre and post a ten session group rehabilitation program between and within groups. Results: Internal consistency was good for all movements (α = 0.84-0.88). Intra-rater reliability (Intraclass correlation coefficient-ICC) was excellent for overall scores of all movements (ICC(1,k) = 0.95-0.99), while inter-rater reliability was poor to moderate (ICC(1,k) = 0.39-0.78). We found a significant difference in the total movement scores between cLBP and healthy participants (p = 0.001). Within-group comparison (cLBP) showed no significant difference in the total movement score in pre and post-treatment. Conclusion: The perception of differences between normal and pathological movements has been confirmed through the proposed scoring system, which proved to be able to distinguish different populations. This study has many limitations, but these results show that movement analysis could be a useful tool and open the door to quantifying the identified parameters through future studies

Tissue Resources for the Functional Annotation of Animal Genomes

In order to generate an atlas of the functional elements driving genome expression in domestic animals, the Functional Annotation of Animal Genome (FAANG) strategy was to sample many tissues from a few animals of different species, sexes, ages, and production stages. This article presents the collection of tissue samples for four species produced by two pilot projects, at INRAE (National Research Institute for Agriculture, Food and Environment) and the University of California, Davis. There were three mammals (cattle, goat, and pig) and one bird (chicken). It describes the metadata characterizing these reference sets (1) for animals with origin and selection history, physiological status, and environmental conditions; (2) for samples with collection site and tissue/cell processing; (3) for quality control; and (4) for storage and further distribution. Three sets are identified: set 1 comprises tissues for which collection can be standardized and for which representative aliquots can be easily distributed (liver, spleen, lung, heart, fat depot, skin, muscle, and peripheral blood mononuclear cells); set 2 comprises tissues requiring special protocols because of their cellular heterogeneity (brain, digestive tract, secretory organs, gonads and gametes, reproductive tract, immune tissues, cartilage); set 3 comprises specific cell preparations (immune cells, tracheal epithelial cells). Dedicated sampling protocols were established and uploaded in https://data.faang.org/protocol/samples. Specificities between mammals and chicken are described when relevant. A total of 73 different tissues or tissue sections were collected, and 21 are common to the four species. Having a common set of tissues will facilitate the transfer of knowledge within and between species and will contribute to decrease animal experimentation. Combining data on the same samples will facilitate data integration. Quality control was performed on some tissues with RNA extraction and RNA quality control. More than 5,000 samples have been stored with unique identifiers, and more than 4,000 were uploaded onto the Biosamples database, provided that standard ontologies were available to describe the sample. Many tissues have already been used to implement FAANG assays, with published results. All samples are available without restriction for further assays. The requesting procedure is described. Members of FAANG are encouraged to apply a range of molecular assays to characterize the functional status of collected samples and share their results, in line with the FAIR (Findable, Accessible, Interoperable, and Reusable) data principles

Cochrane Rehabilitation "tagging" of Cochrane Reviews 1996 - August 2018

This dataset contains all reviews and protocols published by Cochrane (titles, abstracts and URLs), screened by the Cochrane Rehabilitation Review Committee, and 'tagged' for relevance to rehabilitation, professional groups involved, and broad clinical area. Duplicate publications (including completed reviews published after a published protocol and updated reviews published during the screening period) are highlighted in column F based on Access Number. Last updated 17 November 2018

Cochrane e "rehabilitation 2030: a call for action" dell'Organizzazione Mondiale della SanitÃ

The World Health Organization (WHO) has launched in February 2017 "Rehabilitation 2030: a call for action". This is likely to have a deep impact in the Health Systems in the next few years. The new Cochrane Rehabilitation Field has been invited by WHO as a relevant stakeholder in this effort. WHO recognizes the dramatic changes in health and demographic profiles of populations that are characterizing the 21st century. Main goals of WHO are to ensure healthy lives and promote well-being for all at all ages, and to promote healthy life expectancy

Cochrane Rehabilitation: un nuovo field per la produzione e disseminazione delle evidenze

After approval by Cochrane Steering Group, Cochrane Rehabilitation has been launched on 16th December 2016. The aim of Cochrane Rehabilitation is to bridge between Cochrane and Rehabilitation stakeholders, systematically identifying and spreading evidence, but also improving its quality and quantity production per clinical needs

Quantitative Kinematic Assessment of the Sit-to-Stand Transition using an IMU Sensor

Objective: The sit-to-stand transition is an important task for the evaluation of physical independence, especially in fragile subjects like elderly patients, to monitor and reduce the risk of falls or damage. This study aims at assessing the kinematic characteristics of the sit-to-stand transition from a quantitative perspective, using a wireless IMU sensor, and describes a set of parameters suitable for evaluating the movement performance in everyday practice. Methods: An acquisition campaign was designed and carried out on 20 healthy subjects and 13 patients to evaluate acceleration and angular velocity generated during a sit-to-stand task. For each subject, at least four acquisitions were performed, to create a final dataset of 173 acquisitions. The values of the proposed parameters were computed, and results were analyzed with descriptive statistics. Results: According to the proposed parameters definitions and the analyzed dataset, acceleration and angular velocity-related parameters present statistically significant differences between healthy and pathological data samples, unlike total time TT

Muscle Power in Patients with Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-analysis

: This study aimed to review the impact of training on muscle power in patients with chronic obstructive pulmonary disease (COPD). Randomized controlled trials evaluating the effects of exercise-based interventions on limbs muscle power and rate of force development in COPD patients were investigated. Five international databases were searched until October 2022. Meta-analyses were performed calculating the mean difference or standardized mean difference. Risk of bias in studies was assessed using Cochrane Risk of Bias tool 2.0. A total of nine studies were included in the analysis. There were concerns about risk of bias in seven out of nine studies. Comparison of exercising and non-exercising groups showed a significant effect of exercise in improving muscle power (P=0.0004) and rate of force development (P<0.001), in five and three trials, respectively. Four studies comparing different trainings showed no significant results on muscle power (P=0.45). Eight to 16 weeks of exercise-based intervention versus no intervention might be beneficial to enhance upper and lower limbs muscle power and rate of force development in people with COPD. In contrast, muscle power did not improve when different training modalities were compared. Future studies performing power training in COPD patients are encouraged