A Thematic Exploration of For Colored Girls Who Have Considered Suicide/ When the Rainbow is Enuf, by Ntozake Shange

White customs and values have traditionally monopolized commercial theatre. It is not until recently that theatre has taken on multicultural influences in order to incorporate minorities into the audience. There are many artists who have pushed beyond the barrier of modern traditional theatre and influenced their generation One of these artists has challenged not only traditional theatre, but also addressed gender and race issues as well, with controversial results. This artist is named Ntozake Shange and the play that received so much attention is for colored girls who have considered suicide/ when the rainbow is enuf. This piece is intended to speak to women of color and to offer guidance for Black girls. The thesis covers a brief history of Shange\u27s life and experiences into the piece. The paper also addresses Shange\u27s intentions for the piece as it evolved from writing to production and then onto the Broadway stage. Shange termed her work a choreopoem that, by definition, incorporated music, dance, and poetry. Each of these three elements flow together creating a performance that is organic in nature. African storytelling, religion, dance, and music inspired the choreopoem. In order to demonstrate Shange\u27s intentions for the piece, the thesis then describes each element of a choreopoem and analyzes Shange\u27s use of it within for colored girls. Next, the paper discusses the play by analyzing the content of related poems in the piece. By doing this, the paper pulls out certain pieces of subject matter in order to prove Shange\u27s intentions. As well as discussing the performance, the thesis briefly touches upon some critical reactions to the piece and influences it has had on the audience. By acknowledging the awards and impact the piece has had, this analyzes whether or not Shange\u27s intentions were successful

Investigations into zooplankton assemblages off the west coast of Scotland

Zooplankton assemblages were examined from waters off the west coast of Scotland encompassing the Firths of Lorn and Clyde, the North Channel, and the Malin Shelf. Size fractionated samples (coarse, >1000μm; medium, 1000μm-330μm; fine, 330μm-180μm) were collected with a submersible pump from 10m and 30m depth in March (1987) and May (1986) providing a composite picture of the fauna in early and late spring conditions, respectively. The feasibility of using image analysis as a method for processing zooplankton samples was examined. Although a programme was successfully operated to obtain individual measurement data, much work is still required before a fully automated programme for routine use by planktologists is available. Total zooplankton numbers and biomass, and species distributions and relative abundances were examined. Species assemblages were identified using multivariate analyses. Biomass and abundance spectra by size were examined for the major station groupings. In general, meroplankton dominated the fauna in the Firth of Lorn while large numbers of Calanus spp. occurred in the Firth of Clyde. Small copepods such as Oithona spp. were characteristic of the assemblage on the Malin Shelf. Salinity, followed by temperature, showed the strongest association with the observed station clusters. Chlorophyll a and depth did not generally appear to influence station groupings. The potential for the mixing and exchange of zooplankton between the regions of the study area was evaluated. The results suggest that zooplankton may be entrained from the Firth of Clyde by the Scottish Coastal Current during the spring period. The Malin Shelf may also be an important source of zooplankton for the Firth of Lorn during winter months when an onshore flow of Atlantic water occurs

Calculating Cultural Ecosystem Services as Part of Greenspace Management?

Lake related greenspace provides many benefits to residents and visitors, which are often under-valued. The Millennium Ecosystem Assessment Project (2005) proposed the valuation of ecosystem services, defined as regulatory, provisional, ecosystem support and cultural services provided for us by nature, free of charge. The challenge here is: How can we use cultural ecosystem services derived from scenic landscapes for greenspace management and assessment? Cultural ecosystem services received international recognition as part of the Millennium Ecosystem Assessment Project (2005). Also, as part of ecosystems services, are regulatory, provisional and ecosystem support. For this paper we are particularly concerned with cultural services, which include recreation, science and education, spiritual/historic as well as aesthetic functions. De Groot et al (2002) and Farber et al (2006) offer a progression of description of cultural Ecosystem services. De Groot et al (2002) describes Information functions as including; aesthetic information, recreation, cultural artistic information and spiritual/historic information. Farber et al (2005) for cultural services include; aesthetic, recreation, science/education, and spiritual/historic functions. This paper presents ecosystem cultural services related to water based scenic landscape resources and then applies it to an Upstate New York lake landscape. A very careful accounting of greenspace ecosystem services is presented as they are applied to lakeshore residents, village residents and town/watershed residents and lake greenspace users utilizing user benefit calculations to yield over 10.6 million dollars of benefits per year (Smardon 2018)

Tracing the historical growth of gerontology

The question of whether gerontology is an emerging new discipline or a variation of older ones is being debated

Dopamine neurons create Pavlovian conditioned stimuli with circuit-defined motivational properties.

Environmental cues, through Pavlovian learning, become conditioned stimuli that guide animals toward the acquisition of rewards (for example, food) that are necessary for survival. We tested the fundamental role of midbrain dopamine neurons in conferring predictive and motivational properties to cues, independent of external rewards. We found that brief phasic optogenetic excitation of dopamine neurons, when presented in temporal association with discrete sensory cues, was sufficient to instantiate those cues as conditioned stimuli that subsequently both evoked dopamine neuron activity on their own and elicited cue-locked conditioned behavior. Notably, we identified highly parcellated functions for dopamine neuron subpopulations projecting to different regions of striatum, revealing dissociable dopamine systems for the generation of incentive value and conditioned movement invigoration. Our results indicate that dopamine neurons orchestrate Pavlovian conditioning via functionally heterogeneous, circuit-specific motivational signals to create, gate, and shape cue-controlled behaviors

3D migration of cells solving an inverse problem

International audienceTraction Force Microscopy (TFM) is an inverse method that allows to obtain the stress field applied by a living cell on the environment on the basis of a pointwise knowledge of the displacement produced by the cell itself during its migration. This biophysical problem, usually addressed in terms of Green functions, can be alternatively tackled in a variational framework. In such a case, a suitable penalty functional has to be minimized. The resulting Euler-Lagrange equations include both the direct problem based on the linear elasticity operator as well as an equation built on its adjoint. Results from a two-dimensional model, i.e. where living cancer cells are migrating on a plane substrate, are briefly presented. While the mathematics is well established also in the three-dimensional case, i.e. where cells are completely embedded in the gel matrix, the experimental data needed are more difficult to obtain than the two-dimensional counterpart. First steps towards the complete three-dimensional traction reconstruction are reported

Track Reconstruction Progress from the DMTPC Directional Dark Matter Experiment

he Dark Matter Time Projection Chamber (DMTPC) collaboration is developing prototype detectors to measure both the energies and directions of nuclear recoils. The intended application is to exploit the expected directional anisotropy of dark matter velocities at Earth to unambiguously observe dark matter induced recoils. The detector consist of low-pressure CF[subscript 4] TPC's with CCD cameras, PMT's, and charge amplifiers for readout. This talk gives an overview of the experiment and describes recent advances in hardware and analysis

Pro-inflammatory cytokines play a key role in the development of radiotherapy-induced gastrointestinal mucositis

Background: Mucositis is a toxic side effect of anti-cancer treatments and is a major focus in cancer research. Pro-inflammatory cytokines have previously been implicated in the pathophysiology of chemotherapy-induced gastrointestinal mucositis. However, whether they play a key role in the development of radiotherapy-induced gastrointestinal mucositis is still unknown. Therefore, the aim of the present study was to characterise the expression of pro-inflammatory cytokines in the gastrointestinal tract using a rat model of fractionated radiotherapy-induced toxicity. Methods: Thirty six female Dark Agouti rats were randomly assigned into groups and received 2.5 Gys abdominal radiotherapy three times a week over six weeks. Real time PCR was conducted to determine the relative change in mRNA expression of pro-inflammatory cytokines IL-1β, IL-6 and TNF in the jejunum and colon. Protein expression of IL-1β, IL-6 and TNF in the intestinal epithelium was investigated using qualitative immunohistochemistry. Results: Radiotherapy-induced sub-acute damage was associated with significantly upregulated IL-1β, IL-6 and TNF mRNA levels in the jejunum and colon. The majority of pro-inflammatory cytokine protein expression in the jejunum and colon exhibited minimal change following fractionated radiotherapy. Conclusions: Pro-inflammatory cytokines play a key role in radiotherapy-induced gastrointestinal mucositis in the sub-acute onset setting.Zhi Yi Ong, Rachel J. Gibson, Joanne M. Bowen, Andrea M. Stringer, Jocelyn M. Darby, Richard M. Logan, Ann S.J. Yeoh, Dorothy M. Keef

Interactions between Mediterranean diet supplemented with dairy foods and the gut microbiota influence cardiovascular health in an Australian population

The impact of a Mediterranean diet on the intestinal microbiome has been linked to its health benefits. We aim to evaluate the effects of a Mediterranean diet supplemented with dairy foods on the gut microbiome in Australians at risk of cardiovascular disease. In a randomised controlled cross-over study, 34 adults with a systolic blood pressure ≥120 mmHg and with risk factors for cardiovascular disease were randomly allocated to a Mediterranean diet with 3–4 daily serves of dairy foods (Australian recommended daily intake (RDI) of 1000–1300 mg per day (MedDairy)) or a low-fat (LFD) control diet. Between each 8-week diet, participants underwent an 8-week washout period. Microbiota characteristics of stool samples collected at the start and end of each diet period were determined by 16S rRNA amplicon sequencing. MedDairy-associated effects on bacterial relative abundance were correlated with clinical, anthropometric, and cognitive outcomes. No change in the overall faecal microbial structure or composition was observed with either diet (p \u3e 0.05). The MedDairy diet was associated with changes in the relative abundance of several bacterial taxa, including an increase in Butyricicoccus and a decrease in Colinsella and Veillonella (p \u3c 0.05). Increases in Butyricicoccus relative abundance over 8 weeks were inversely correlated with lower systolic blood pressure (r = −0.38, p = 0.026) and positively correlated with changes in fasting glucose levels (r = 0.39, p = 0.019), specifically for the MedDairy group. No significant associations were observed between the altered taxa and anthropometric or cognitive measures (p \u3e 0.05). Compared to a low-fat control diet, the MedDairy diet resulted in changes in the abundance of specific gut bacteria, which were associated with clinical outcomes in adults at risk of CVD