A non-local perturbation of the logistic equation in IR N

A logistic equation in the whole space is considered. In this problem, a non-local perturbation is included. We establish a new sub-supersolution method forgeneral nonlocal elliptic equations and, consequently, we obtain the existence ofpositive solutions of a nonlocal logistic equation.Ministerio de Economía y Competitividad (MINECO). EspañaEuropean Commission (EC). Fondo Europeo de Desarrollo Regional (FEDER)Conselho Nacional de Desenvolvimento Científico e Tecnológico. BrasilCoordenação de Aperfeiçoamento de Pessoal de Nivel Superior. Brasi

Andragogía y autoaprendizaje en estudiantes de la carrera logística y transporte en un Instituto Superior Público de Santo Domingo, 2022

El presente estudio tuvo como objetivo Identificar la relación que existe entre la Andragogía y el autoaprendizaje en estudiantes de la carrera de logística y transporte de un Instituto de Educación Superior de Santo Domingo, Ecuador, 2022. El enfoque aplicado a la investigación fue cuantitativo, de tipo no experimental, descriptivo y correlacional. Para recolectar la información se utilizaron 2 cuestionarios, a una muestra de 109 estudiantes, los resultados obtenidos a través del SPSS 26. Mediante la prueba de Kolmogórov-Smirnov se estableció que era una prueba no paramétrica, los datos estadísticos de las variables de estudio y sus dimensiones fueron representados en tablas para determinar las frecuencias y porcentajes respectivos. Para la contrastación de hipótesis se empleó el Rho Spearman, siendo el resultado 0.650, con una significancia (p<0.005) En conclusión, se pudo determinar quelas variables estudiadas tienen una relación alta, directa y significativa, y en igual forma las dimensiones de la andragogía: estrategias de iniciación, estrategias metodológicas y evaluación, respecto al autoaprendizaje. Finalmente se realizan varias recomendaciones para adaptar los cambios andragógicos significativos en los procesos de autoaprendizaje, aplicados a docentes y estudiantes universitarios

Crescer em família: a permanência no Acolhimento Familiar.

O Acolhimento Familiar oferece um contexto de vida à criança retirada da sua família biológica, por um período de tempo indeterminado que se pode prolongar, no limite, até à maioridade ou independência. Um contexto familiar estável permite desenvolver sentimentos de segurança e de permanência associados à possibilidade de manutenção dos contactos com a sua família biológica. O objetivo deste artigo é, após uma breve caracterização do sistema de proteção de crianças e jovens português, analisar a permanência no acolhimento familiar de 2006 a 2011, a partir dos relatórios de caracterização das crianças e jovens em situação de acolhimento. De seguida procedemos à apresentação e discussão de dados recolhidos num estudo desenvolvido no distrito do Porto, englobando as 289 crianças que se encontravam acolhidas em Maio de 2011, e que representavam 52% das colocações familiares de crianças em Portugal. Os resultados foram apurados com a aplicação de um formulário de recolha de dados e através da realização de 52 entrevistas a acolhedores. Entre os resultados principais destacam-se os longos períodos de estadia, a permanência da criança na família acolhedora inicial e a avaliação global positiva dos resultados obtidos, o que nos permite identificar um conjunto de desafios que se colocam no futuro imediato ao acolhimento familiar português

Increasing Acid Concentration, Time and Using a Two-Part Silane Potentiates Bond Strength of Lithium Disilicate-Reinforced Glass Ceramic to Resin Composite:An Exploratory Laboratory Study

There is still a lack of consensus concerning the recommended etching concentration, application time and type of silane when bonding lithium disilicate-reinforced glass ceramics manufactured by CAD/CAM. The purpose of this study was thus to conduct an in vitro study which investigates the influence of hydrofluoric acid (HF) concentration, etching time and silane type on the microtensile bond strength (μTBS) of lithium disilicate to resin composites. Thirty-nine IPS e.max CAD blocks were randomly divided between thirteen groups (n = 3). The variables were HF concentration (9.5 or 4.9%), etching time (20 or 60 s) and silane type (Bis-Silane, Monobond Plus and ESPE Sil Silane). The blocks were cut into beams, aged for 10,000 cycles in a thermocycler and submitted to tensile stress to determine μTBS. A control group featuring the Monobond Etch & Prime (MEP) agent that combines etching/silanisation into a simultaneous process was also added. This group was discarded from the analysis due to only having pre-test failures. The data were analysed using a three-way ANOVA (α = 0.05). The HF concentration, etching time and silane type significantly influenced μTBS (p < 0.001). Significant interactions between time and silane type (p = 0.004), HF concentration and silane type (p < 0.001) and among the three factors (p < 0.001) were noted. Etching lithium disilicate with 9.5% HF (60 s), followed by the application of Bis-Silane, resulted in the highest μTBS (16.6 ± 9.0 MPa). The highest concentration and etching time under study, combined with a two-part silane, resulted in the highest bond strength, while the application of MEP showed a complete pre-test failure

Propuesta de un plan de optimización de procesos productivos para la elaboración de polos de algodón que mejorará la productividad en la empresa textil Ary Baby S.R.L – Chiclayo, 2014

El principal objetivo de este trabajo ha sido Proponer un plan de optimización de procesos productivos para la elaboración de polos de algodón y mejorar la productividad de la empresa ARY BABY S.R.L., que fueron realizados dentro de ella así como todas las actividades inmersas dentro del proceso productivo de la misma, deben considerarse dentro de la planificación de los pasos a seguir para lograr los objetivos propuestos. En los resultados observamos que el 60% de los encuestados indicó que fueron capacitados para realizar sus actividades con eficiencia, mientras que el 40% de los encuestados indicaron que no tuvieron esta capacitación. El 53,3% de los encuestados indicaron que tienen una cartera de proveedores tomando en cuenta la calidad, oportunidad y precio de la materia prima. En relación a la eficiencia productiva de la empresa S.R.L. se conoce que el 53,3% de los encuestados afirma que el tiempo de producción de la empresa depende del desempeño del empleado, en base a estos resultados se diseñó el plan de optimización para la elaboración de polos de algodón en la empresa ARY BABY S.R.L, .sustentados en los principios de calidad y productividad.Tesi

Valvular heart disease: shifting the focus to the myocardium

Adverse cardiac remodelling is the main determinant of patient prognosis in degenerative valvular heart disease (VHD). However, to give an indication for valvular intervention, current guidelines include parameters of cardiac chamber dilatation or function which are subject to variability, do not directly reflect myocardial structural changes, and, more importantly, seem to be not sensitive enough in depicting early signs of myocardial dysfunction before irreversible myocardial damage has occurred. To avoid irreversible myocardial dysfunction, novel biomarkers are advocated to help refining indications for intervention and risk stratification. Advanced echocardiographic modalities, including strain analysis, and magnetic resonance imaging have shown to be promising in providing new tools to depict the important switch from adaptive to maladaptive myocardial changes in response to severe VHD. This review, therefore, summarizes the current available evidence on the role of these new imaging biomarkers in degenerative VHD, aiming at shifting the clinical perspective from a valve-centred to a myocardium-focused approach for patient management and therapeutic decision-making

Diseño y desarrollo de un dispositivo para captura audiovisual en escenarios de turismo de aventura

In several places of Santander southern provinces - Comunera and Guanentá - adventure tourism represents an important part in the local economy. Activities like rafting, rappel, caving, and paragliding among others take place in natural surroundings, where taking photos and making videos to record the tourists´experiences have increased the commercial demand for the audio-visual market. Technology is being developed in the same direction of the audiovisual language that is being used to promote touristic services in the region. Current audio-visual devices are considered to have limitations in terms of the risks assumed by its operator when trying to get shots in dangerous situations. For that reason, ERR1 (Extreme Recording Robot 1) has been designed and developed as a device that mitigates that situation looking forward to overcome any existing limitation; to achieve that, telematics and robotic tools were used.En varias regiones de las provincias Comunera y Guanentá, al sur del departamento de Santander, el turismo de aventura representa un renglón importante de su economía. Este se realiza en escenarios naturales, donde se desarrollan, entre otras, actividades como rafting, rapel, espeleísmo y parapente. Allí, el registro en fotografías y videos de las experiencias vividas por el turista han contribuido al incremento de la demanda comercial para este sector. La tecnología se ha desarrollado paralelamente con el lenguaje audiovisual que se usa para ofertar los servicios turísticos de la región. Los dispositivos actuales de captura audiovisual, tienen grandes limitaciones para lograr una toma precisa en los escenarios naturales donde se desarrollan actividades de turismo de aventura, poniendo en riesgo la integridad física del operario. Por tal razón, se diseñó y desarrolló el ERR1 (Extreme Recording Robot 1), dispositivo que permitió mitigar la situación planteada y superar así las limitaciones existentes. Para ello se utilizaron herramientas robóticas y telemáticas

The H2020 OCRE Project Opens the Gates of the Commercial Cloud and EO Services Usage to the Research Community

Cloud and Earth Observation (EO) based services offer the European Research community a wealth of powerful tools. However, for many researchers these tools are currently out of reach. It is difficult to find and select suitable services. Establishing agreements with cloud and EO service providers and ensuring legal and technical compliance requires specialist skills and takes an inordinate amount of time. Equally, service providers find it difficult to reach and meet the needs of the research community in technical, financial and legal areas. The Open Clouds for Research Environments consortium (OCRE) will change this, by putting in place an easy adoption route. In the autumn of 2019, OCRE will run a pan-European tender and establish framework agreements with service providers who meet the requirements of the research community. 10.000 European research and education institutes will be able to directly consume these offerings via the European Open Science Cloud service catalogue, through ready-to-use agreements. They will not have to run a tender of their own. In addition, to stimulate usage, OCRE will make available 9.5 million euro in service credits (vouchers), through adoption funds from the European Commission. OCRE is a pioneer project without precedence, with potentially high impact in the future EO market activities and evolution of service offering, with the objective to burst the usage of EO commercial services by the research environment

The professional practice of social agents in youth leisure: strategies for intervention

[ES] Basándose en una muestra de treinta y cuatro (34) agentes sociales, este artículo analiza su práctica profesional en materia de ocio juvenil, a nivel nacional. Se incide en las estrategias utilizadas en la intervención, a saber: objetivos; metodología y coordinación inter e intra institucional; fuentes de financiación; estrategias de comunicación y difusión; y sistema de evaluación. Ante ello, se afrontan como principales objetivos identificar la práctica profesional en materia de ocio juvenil desde la perspectiva de los agentes sociales y definir indicadores que sean el punto de partida para identificar buenas prácticas en este campo. Se aborda un marco metodológico centrado en la investigación evaluativa de carácter diagnóstica, exploratoria y descriptiva. En este contexto, se configura un estudio piloto, cuyas técnicas de recogida de datos sobre la práctica profesional de los encuestados han sido en primer lugar, el diseño de un cuestionario abierto, seguido de un segundo cuestionario cerrado que ha partido del análisis de contenido de las respuestas dadas al primero, con el fin de identificar indicadores comunes de la práctica profesional y así poder establecer un patrón de referencia que pueda validarse desde la misma. Finalmente se identifican ocho indicadores clave como referentes para desarrollar una intervención de calidad en materia de ocio juvenil, desde el trabajo y las valoraciones de los expertos consultados. [EN] This paper analyses the professional practice of thirty-four social agents who work in the field of youth leisure in Spain. It focuses on the strategies they use in intervention, namely objectives; inter- and intra-institutional methodology and coordination; funding sources; communication and dissemination strategies; and evaluation system. The main objectives were to identify professional practice in youth leisure from the perspective of social agents and define indicators that could serve as a starting point for identifying good practices in this field. The methodological framework used evaluative research that was diagnostic, exploratory and descriptive in nature. A pilot study was conducted. Data on the professional practice of the respondents were initially collected by the use of an open-ended questionnaire, followed by the administration of a closed questionnaire based on the content analysis of the answers given to the first questionnaire. The aim was to identify common indicators of professional practice and establish a benchmark that could be validated. The results identified eight key indicators that could be used as benchmarks to develop high-quality intervention in youth leisure, which relied on the work and the assessment of the experts consulted

Urinary estrogen metabolites and self-reported infertility in women infected with Schistosoma haematobium

Background Schistosomiasis is a neglected tropical disease, endemic in 76 countries, that afflicts more than 240 million people. The impact of schistosomiasis on infertility may be underestimated according to recent literature. Extracts of Schistosoma haematobium include estrogen-like metabolites termed catechol-estrogens that down regulate estrogen receptors alpha and beta in estrogen responsive cells. In addition, schistosome derived catechol-estrogens induce genotoxicity that result in estrogen-DNA adducts. These catechol estrogens and the catechol-estrogen-DNA adducts can be isolated from sera of people infected with S. haematobium. The aim of this study was to study infertility in females infected with S. haematobium and its association with the presence of schistosome-derived catechol-estrogens. Methodology/Principal Findings A cross-sectional study was undertaken of female residents of a region in Bengo province, Angola, endemic for schistosomiasis haematobia. Ninety-three women and girls, aged from two (parents interviewed) to 94 years were interviewed on present and previous urinary, urogenital and gynecological symptoms and complaints. Urine was collected from the participants for egg-based parasitological assessment of schistosome infection, and for liquid chromatography diode array detection electron spray ionization mass spectrometry (LC/UV-DAD/ESI-MSn) to investigate estrogen metabolites in the urine. Novel estrogen-like metabolites, potentially of schistosome origin, were detected in the urine of participants who were positive for eggs of S. haematobium, but not detected in urines negative for S. haematobium eggs. The catechol-estrogens/ DNA adducts were significantly associated with schistosomiasis (OR 3.35; 95% CI 2.32–4.84; P≤0.001). In addition, presence of these metabolites was positively associated with infertility (OR 4.33; 95% CI 1.13–16.70; P≤0.05). Conclusions/Significance Estrogen metabolites occur widely in diverse metabolic pathways. In view of the statistically significant association between catechol-estrogens/ DNA adducts and self-reported infertility, we propose that an estrogen-DNA adduct mediated pathway in S. haematobium-induced ovarian hormonal deregulation could be involved. In addition, the catechol-estrogens/ DNA adducts described here represent potential biomarkers for schistosomiasis haematobia