Teste baseado em casos de uso.

Os casos de uso consistem em um meio de se capturar as funcionalidades de um sistema de forma centrada no usuário. Entender como o usuário interage com um sistema é um aspecto importante quando se tem como objetivo entregar um produto que atenda às suas necessidades.bitstream/CNPTIA/10210/1/bp10.pdfAcesso em: 28 maio 2008

Teste de fluxo de dados de programas com ponteiros e registros.

Dois modelos mais precisos de análise de fluxo de dados voltados para o teste de programas que utilizaram ponteiros e campos de registros são apresentados. Os modelos propostos são baseados em uma abordagem conservadora e foram implementados na ferramenta POKE-TOOL. A conjectura é que a análise de fluxo de dados mais precisa aumenta a eficácia do teste a um custo razoável .Para investigar essa conjectura, um estudo de caso foi realizado para avaliar a eficácia eo custo da utilização dos dois modelos no teste com duas famílias diferentes de critérios de teste baseados em análise de fluxo de dados. Os resultados obtidos indicam que a eficácia dos modelos dependem do programa e dos defeitos que ele contém. A segunda observação em especial indica que existem defeitos cuja detecção é facilitada quando os modelos propostos são utilizados. Para uma das famílias de critérios de teste, foi observado que o custo adicional causado pela análise mais precisa de fluxo de dados é razoável.bitstream/CNPTIA/9956/1/bolpesq4.pdfAcesso em: 28 maio 2008

Processo de depuração depois do teste: definição e análise.

O objetivo da realização deste trabalho foi analisar em detalhes o processo de depuração que ocorre depois da atividade de teste. Por tanto, vários processos de depuração de software foram analisados. Baseado nessa análise foi definido um processo de Depuração depois do teste (DDT) que enfativa os seguintes aspectos: identificação, avaliação e refinamento sucessivo de sintomas internos até a localização do defeito; e tipo de informação de teste utilizada. Várias técnicas de depuração foram então avaliadas em termos de mecanismos de apoio ao processo DDT e quanto a sua escabilidade para programas reais. Dessa avaliação, observou-se que os resultados do teste sistemático de software, quando utilizado na depuração, resultam em técnicas de baixo custo e com maiores perspectivas de escabilidade para programas reais. Infelizmente, esses resultados têm sido utilizados apenas para apoiar um dos aspectos do processo DDT- identificação de sintomas internos. Essa observação motiva a definição de estratégias de depuração que utilizem, de maneira eficaz e eficiente, as informações de teste na avaliação e no refinamento de sintomas internos.bitstream/CNPTIA/9957/1/bolpesq5.pdfAcesso em: 28 maio 2008

Machine-Learning Approach to Determine Surface Quality on a Reactor Pressure Vessel (RPV) Steel

Surface quality measures such as roughness, and especially its uncertain character, affect most magnetic non-destructive testing methods and limits their performance in terms of an achievable signal-to-noise ratio and reliability. This paper is primarily focused on an experimental study targeting nuclear reactor materials manufactured from the milling process with various machining parameters to produce varying surface quality conditions to mimic the varying material surface qualities of in-field conditions. From energising a local area electromagnetically, a receiver coil is used to obtain the emitted Barkhausen noise, from which the condition of the material surface can be inspected. Investigations were carried out with the support of machine-learning algorithms, such as Neural Networks (NN) and Classification and Regression Trees (CART), to identify the differences in surface quality. Another challenge often faced is undertaking an analysis with limited experimental data. Other non-destructive methods such as Magnetic Adaptive Testing (MAT) were used to provide data imputation for missing data using other intelligent algorithms. For data reinforcement, data augmentation was used. With more data the problem of ‘the curse of data dimensionality’ is addressed. It demonstrated how both data imputation and augmentation can improve measurement datasets

The At Home/Chez Soi trial protocol: a pragmatic, multi-site, randomised controlled trial of a Housing First intervention for homeless individuals with mental illness in five Canadian cities

This article was published in BMJ Open following peer review and can also be viewed on the journal’s website at http://bmjopen.bmj.comIntroduction: Housing First is a complex housing and support intervention for homeless individuals with mental health problems. It has a sufficient knowledge base and interest to warrant a test of wide-scale implementation in various settings. This protocol describes the quantitative design of a Canadian five city, $110 million demonstration project and provides the rationale for key scientific decisions. Methods: A pragmatic, mixed methods, multi-site field trial of the effectiveness of Housing First in Vancouver, Winnipeg, Toronto, Montreal and Moncton, is randomising approximately 2500 participants, stratified by high and moderate need levels, into intervention and treatment as usual groups. Quantitative outcome measures are being collected over a 2-year period and a qualitative process evaluation is being completed. Primary outcomes are housing stability, social functioning and, for the economic analyses, quality of life. Hierarchical linear modelling is the primary data analytic strategy. Ethics and dissemination: Research ethics board approval has been obtained from 11 institutions and a safety and adverse events committee is in place. The results of the multi-site analyses of outcomes at 12 months and 2 years will be reported in a series of core scientific journal papers. Extensive knowledge exchange activities with non-academic audiences will occur throughout the duration of the project.This work was supported by a contract from Health Canada administrated by the Mental Health Commission of Canada

Design, synthesis, characterization, bio-molecular docking studies, and biological activity of (4-amino-2-(aryl/alkylamino)thiazol-5-yl)(6-methylbenzo[d] thiazol-2-yl)methanone derivatives

A series of novel (4-amino-2-(aryl/alkylamino)thiazol-5-yl)(6-methylbenzo[d]thiazol-2-yl)methanone compounds have been synthesized. They have been characterized by elemental analysis, IR, 1H and 13C NMR and mass spectral techniques. All the synthesized compounds have been screened for their antibacterial potential and show significant antibacterial activity. Among these (4-amino-2-(4-chlorophenyl)amino)thiazol-5-yl)(6-methylbenzo[d]thiazol-2-yl)methanone is more active. Moreover, the compound 3d shows promising antioxidant activity activity. The compounds have been further evaluated for their potential for DNA cleavage and two compounds completely cleaved DNA. Two of the compounds have been evaluated for their anti-proliferative activity against breast cancer cell lines. The IC50 value of the compound (4-amino-2-(4-chlorophenyl)amino)thiazol-5-yl)(6-methylbenzo[d]thiazol-2-yl)methanone against the cell line MCF-7 is found to be 10 µg/mL. Four compounds have been docked towards 5077 receptor protein. Molecular docking shows very good interaction with protein. In this (4-amino-2-(4-methoxyphenyl)amino)thiazol-5-yl)(6-methylbenzo[d]thiazol-2-yl)methanone has the highest binding interaction with the protein.

Design, synthesis, characterization, bio-molecular docking studies, and biological activity of (4-amino-2-(aryl/alkylamino)thiazol-5-yl)(6-methylbenzo[d] thiazol-2-yl)methanone derivatives

1621-1628A series of novel (4-amino-2-(aryl/alkylamino)thiazol-5-yl)(6-methylbenzo[d]thiazol-2-yl)methanone compounds have been synthesized. They have been characterized by elemental analysis, IR, 1H and 13C NMR and mass spectral techniques. All the synthesized compounds have been screened for their antibacterial potential and show significant antibacterial activity. Among these (4-amino-2-(4-chlorophenyl)amino)thiazol-5-yl)(6-methylbenzo[d]thiazol-2-yl)methanone is more active. Moreover, the compound 3d shows promising antioxidant activity activity. The compounds have been further evaluated for their potential for DNA cleavage and two compounds completely cleaved DNA. Two of the compounds have been evaluated for their anti-proliferative activity against breast cancer cell lines. The IC50 value of the compound (4-amino2-(4-chlorophenyl)amino)thiazol-5-yl)(6-methylbenzo[d]thiazol-2-yl)methanone against the cell line MCF-7 is found to be 10 µg/mL. Four compounds have been docked towards 5077 receptor protein. Molecular docking shows very good interaction with protein. In this (4-amino-2-(4-methoxyphenyl)amino)thiazol-5-yl)(6-methylbenzo[d]thiazol-2-yl)methanone has the highest binding interaction with the protein

Indigenous and Non-Indigenous People Experiencing Homelessness and Mental Illness in Two Canadian Cities: A Retrospective Analysis and Implications for Culturally Informed Action

Objectives Indigenous people in Canada are not only over-represented among the homeless population but their pathways to homelessness may differ from those of non-Indigenous people. This study investigated the history and current status of Indigenous and non-Indigenous people experiencing homelessness and mental illness. We hypothesised that compared with non-Indigenous people, those who are Indigenous would demonstrate histories of displacement earlier in life, higher rates of trauma and self-medication with alcohol and other substances. Design and setting Retrospective data were collected from a sample recruited through referral from diverse social and health agencies in Winnipeg and Vancouver. Participants Eligibility included being 19 years or older, current mental disorder and homelessness. Measures Data were collected via interviews, using questionnaires, on sociodemographics (eg, age, ethnicity, education), mental illness, substance use, physical health, service use and quality of life. Univariate and multivariable models were used to model the association between Indigenous ethnicity and dependent variables. Results A total of 1010 people met the inclusion criteria, of whom 439 self-identified as Indigenous. In adjusted models, Indigenous ethnicity was independently associated with being homeless at a younger age, having a lifetime duration of homelessness longer than 3 years, post-traumatic stress disorder, less severe mental disorder, alcohol dependence, more severe substance use in the past month and infectious disease. Indigenous participants were also nearly twice as likely as others (47% vs 25%) to have children younger than 18 years. Conclusions Among Canadians who are homeless and mentally ill, those who are Indigenous have distinct histories and current needs that are consistent with the legacy of colonisation. Responses to Indigenous homelessness must be developed within the context of reconciliation between Indigenous and non-Indigenous Canadians, addressing trauma, substance use and family separations