Sociedad y medio ambiente: estudio del movimiento ecologista en Navarra

El problema medioambiental puede entenderse como uno de los mayores retos a los que se enfrentan las sociedades contemporáneas. Como consecuencia de las ambivalencias que trajo consigo la Revolución industrial, el mundo está siendo sometido a importantes cambios que afectan a la supervivencia a largo plazo del planeta y de los seres que lo habitan. Este es el principal discurso del movimiento ecologista actual, un movimiento socio-político que reivindica una necesaria armonía entre lo social y lo natural. Los objetivos generales de esta investigación son dos: conocer los antecedentes y el desarrollo del ecologismo, y analizar la situación actual del movimiento ecologista navarro. La metodología empleada consiste en la revisión bibliográfica sobre este tema, y la realización de entrevistas semiestructuradas a miembros del movimiento. Con todo ello, podremos comprobar que la acción social del voluntariado así como las nuevas tecnologías son el motor del movimiento ecologista en NavarraThe environmental problem can be understood as one of the biggest challenges facing contemporary societies. As a result of the ambivalence brought about by the Industrial Revolution, the world is undergoing major changes affecting the long-term survival of the planet and the beings that inhabit it. This is the keynote address of the current environmental movement, a sociopolitical movement that claims a necessary harmony between the social and the natural. The overall objectives of this research are two: know the background and development of environmentalism, and analyze the current situation of the environmental movement in Navarra. The methodology consists of a literature review on this topic, and semi-structured interviews with members of the movement. With all of this, we can see that social action volunteering and new technologies are the engine of the environmental movement in NavarraGraduado o Graduada en Sociología Aplicada por la Universidad Pública de NavarraSoziologia Aplikatuan Graduatua Nafarroako Unibertsitate Publikoa

Las artes plásticas en Educación Primaria. Un proyecto para fomentar las capacidades y destrezas, basado en Inteligencias Múltiples.

El presente Trabajo de Fin de Grado trata sobre la Educación de las Artes Plásticas y su práctica en el Sistema Educativo Español. Así como la importancia de la misma para el desarrollo evolutivo de los alumnos. Las metodologías que se deben emplear son las que permiten a los alumnos participar activamente en el proceso de enseñanza- aprendizaje. En esta línea planteo un proyecto de comprensión basado en Inteligencias Múltiples, para trabajar el arte abstracto desde diferentes perspectivas. En definitiva, este trabajo trata de mostrar diferentes alternativas a la tradicional metodología empleada en el Área Curricular de Artes Plásticas y de plantear un proyecto que permita el desarrollo de las diferentes capacidades y destrezas de los alumnos.Grado en Educación Primari

Study of the professional profiles and teacher training of physics teachers between Chile and Mexico

PHYSICS TEACHER TRAINING The physics teachers require, in addition to knowledge of the discipline, development of skills that allow them to plan and implement teaching strategies that help students acquire knowledge of the different branches of physics and their usefulness in different contexts (Arriaga et al., 2017). Thus, teacher training plays a fundamental role and can be approached from two perspectives: initial training (profile) and in-service training (teacher training) (Gómez et al., 2020; Campos, 2020). In Latin America, particularly in Chile and Mexico, the training of physics teachers focuses on their professional profile, so it is necessary to deepen teacher training, so that an ideal profile is achieved to teach physics classes (Ramírez & Medina, 2022). In general, the teaching of teachers can be divided into two: 1) courses on the didactics of physics; and 2) courses on the educational model of the school (Arriaga et al., 2017). In the work we are presenting, a study was conducted about the training of the physics teacher, creating indicators to know the ideal profile of the teacher, and proposing training tools that allow the teacher to approach the ideal profile, and a comparison of the results of the study between teachers of Chile and Mexico. MATERIALS AND METHODS For the preparation of the teacher and authorities’ evaluation instrument, work was carried out during the summer of 2019, taking as a sample authority from the Universidad de Guadalajara and Instituto Politécnico Nacional (both from Mexico) and the Universidad Austral de Chile (Chile). The expert validation methodology (Hernández-Sampieri et al., 2018) was used for the instrument validation and reliability process. The group of experts was made up of 7 doctors in physics education from Mexico, Chile, and Colombia. Application of instruments has been online both in México and Chile in 2022 and using software MAXQDA for the qualitative analysis. RESULTS Up to this moment, the project continues, however there are already some interesting results. The physics teacher requires continuous training, both disciplinary and teaching. The profile of the physics teacher in Mexico is more disciplinary, while in Chile it is a little closer to the teaching profile, therefore, the training options have a different orientation. The impact of both the profile and teacher training in the development of skills in students is still under investigation. REFERENCES Arriaga, C., Mora, C. & Ramírez, M. (2017). Impacto del perfil profesional de los profesores en los resultados académicos de los estudiantes de nuevo ingreso en el curso de introducción a la Física. Latin American Journal of Physics Education, 11(4), 4305-1-7. Campos, M. (2020). Interpretación de gráficas de variables cinemáticas y formación de profesores: un acercamiento a través del Conocimiento Didáctico del Contenido. Doctoral Thesis in Physics Education, Instituto Politécnico Nacional. Gómez, I., Ramírez, M. & Arriaga, C. (2020). El perfil del docente de física como factor en el desarrollo de las competencias del estudiante en el bachillerato. Revista Iberoamericana para la Investigación y el Desarrollo Educativo, 11(21),1-30. Hernández-Sampieri, R., Fernández, C., & Baptista, M. (2018). Metodología de la Investigación. McGraw Hill Education, México. Ramírez, M. & Medina, J. (2022). Estudio comparativo de los perfiles profesionales y formación docente de profesores de física entre Chile y México, In J. Slisko (Ed.). Proceedings of XXIX Workshop New Trends in Physics Teaching (pp. 53), Benemérita Universidad Autónoma de Puebla

Towards a monitoring middleware for cloud services

© 2015 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.Cloud Computing represents a new trend in the development and use of software. Many organizations are currently adopting the use of services that are hosted in the cloud by employing the Software as a Service (SaaS) model. Services are typically accompanied by a Service Level Agreement (SLA), which defines the quality terms that a provider offers to its customers. Many monitoring tools have been proposed to report compliance with the SLA. However, they have some limitations when changes to monitoring requirements must be made and because of the complexity involved in capturing low-level raw data from services at runtime. In this paper, we propose the design of a platform-independent monitoring middleware for cloud services, which supports the monitoring of SLA compliance and provides a report containing SLA violations that may help stakeholders to make decisions regarding how to improve the quality of cloud services. Moreover, our middleware definition is based on the use of [email protected], which allows the dynamic change of quality requirements and/or the dynamic selection of different metric operationalizations (i.e., calculation formulas) with which to measure the quality of services. In order to demonstrate the feasibility of our approach, we show the instantiation of the proposed middleware that can be used to monitor services when deployed on the Microsoft Azure© platform.This research is supported by the Value@Cloud project (TIN2013-46300-R); the Scholarship Program Senescyt - Ecuador; University of Cuenca – Ecuador; and the Microsoft Azure for Research Award ProgramCedillo Orellana, IP.; Jiménez Gómez, J.; Abrahao Gonzales, SM.; Insfrán Pelozo, CE. (2015). Towards a monitoring middleware for cloud services. IEEE. https://doi.org/10.1109/SCC.2015.68

Programa de estimulación temprana: parálisis cerebral

Se entiende por Atención Temprana el conjunto de intervenciones, dirigidas a la población infantil de 0-6 años, a la familia y al entorno, que tienen por objetivo dar respuesta lo más pronto posible a las necesidades transitorias o permanentes que presentan los niños con trastornos en su desarrollo o que tienen el riesgo de padecerlos. Estas intervenciones, que deben considerar la globalidad del niño, han de ser planificadas por un equipo de profesionales de orientación interdisciplinar o transdisciplinar.” El usuario tiene una edad de 3 años y 4 meses, presenta parálisis cerebral con una hemiplejia derecha, y una pérdida auditiva de 20 dB en el oído derecho. En el área de desarrollo psicomotor tiene un desarrollo aproximado de 10 meses; en el área del lenguaje, 18 meses; en el área cognitiva, 21 meses y en el área de socialización, 25 meses. El objetivo principal de la intervención es mejorar la condición física, consiguiendo un control normal de la postura, así como reconstruir la actividad motora del usuario. La evaluación se llevará a cabo mediante una escala tipo Likert teniendo como referencia la Guía Portage. Los resultados obtenidos tras la intervención han sido favorables como se puede ver en dicho apartado

PAX4 preserves endoplasmic reticulum integrity preventing beta cell degeneration in a mouse model of type 1 diabetes mellitus

[Aims/hypothesis]: A strategy to enhance pancreatic islet functional beta cell mass (BCM) while restraining inflammation, through the manipulation of molecular and cellular targets, would provide a means to counteract the deteriorating glycaemic control associated with diabetes mellitus. The aims of the current study were to investigate the therapeutic potential of such a target, the islet-enriched and diabetes-linked transcription factor paired box 4 (PAX4), to restrain experimental autoimmune diabetes (EAD) in the RIP-B7.1 mouse model background and to characterise putative cellular mechanisms associated with preserved BCM. [Methods]: Two groups of RIP-B7.1 mice were genetically engineered to: (1) conditionally express either PAX4 (BPTL) or its diabetes-linked mutant variant R129W (mutBPTL) using doxycycline (DOX); and (2) constitutively express luciferase in beta cells through the use of RIP. Mice were treated or not with DOX, and EAD was induced by immunisation with a murine preproinsulin II cDNA expression plasmid. The development of hyperglycaemia was monitored for up to 4 weeks following immunisation and alterations in the BCM were assessed weekly by non-invasive in vivo bioluminescence intensity (BLI). In parallel, BCM, islet cell proliferation and apoptosis were evaluated by immunocytochemistry. Alterations in PAX4- and PAX4R129W-mediated islet gene expression were investigated by microarray profiling. PAX4 preservation of endoplasmic reticulum (ER) homeostasis was assessed using thapsigargin, electron microscopy and intracellular calcium measurements. [Results]: PAX4 overexpression blunted EAD, whereas the diabetes-linked mutant variant PAX4R129W did not convey protection. PAX4-expressing islets exhibited reduced insulitis and decreased beta cell apoptosis, correlating with diminished DNA damage and increased islet cell proliferation. Microarray profiling revealed that PAX4 but not PAX4R129W targeted expression of genes implicated in cell cycle and ER homeostasis. Consistent with the latter, islets overexpressing PAX4 were protected against thapsigargin-mediated ER-stress-related apoptosis. Luminal swelling associated with ER stress induced by thapsigargin was rescued in PAX4-overexpressing beta cells, correlating with preserved cytosolic calcium oscillations in response to glucose. In contrast, RNA interference mediated repression of PAX4-sensitised MIN6 cells to thapsigargin cell death. [Conclusions/interpretation]: The coordinated regulation of distinct cellular pathways particularly related to ER homeostasis by PAX4 not achieved by the mutant variant PAX4R129W alleviates beta cell degeneration and protects against diabetes mellitus. The raw data for the RNA microarray described herein are accessible in the Gene Expression Omnibus database under accession number GSE62846

Tobacco Smoking and Second-Hand Smoke Exposure Impact on Tuberculosis in Children

Mycobacterium tuberculosis; Child; Passive smokingTuberculosis micobacteriana; Niño; Tabaquismo pasivoTuberculosi micobacteriana; Infant; Tabaquisme passiuLittle is known about whether second-hand smoke (SHS) exposure affects tuberculosis (TB). Here, we investigate the association of cigarette smoke exposure with active TB and latent TB infection (LTBI) in children, analyzing Interferon-Gamma Release Assays’ (IGRAs) performance and cytokine immune responses. A total of 616 children from contact-tracing studies were included and classified regarding their smoking habits [unexposed, SHS, or smokers]. Risk factors for positive IGRAs, LTBI, and active TB were defined. GM-CSF, IFN-γ, IL-2, IL-5, IL-10, IL-13, IL-22, IL-17, TNF-α, IL-1RA and IP-10 cytokines were detected in a subgroup of patients. Being SHS exposed was associated with a positive IGRA [aOR (95% CI): 8.7 (5.9–12.8)] and was a main factor related with LTBI [aOR (95% CI): 7.57 (4.79–11.94)] and active TB [aOR (95% CI): 3.40 (1.45–7.98)]. Moreover, IGRAs’ sensitivity was reduced in active TB patients exposed to tobacco. IL-22, GM-CSF, IL-5, TNF-α, IP-10, and IL-13 were less secreted in LTBI children exposed to SHS. In conclusion, SHS is associated with LTBI and active TB in children. In addition, false-negative IGRAs obtained on active TB patients exposed to SHS, together with the decrease of specific cytokines released, suggest that tobacco may alter the immune response.This research was supported by: (i) a grant from the Instituto de Salud Carlos III (PI 13/01546, PI16/01912, and PI18/00411), integrated in the Plan Nacional I+D+I and co-funded by the ISCIII Subdirección General de Evaluación and the Fondo Europeo de Desarrollo Regional (FEDER) and CERCA Programme/Generalitat de Catalunya; and (ii) a grant from the Sociedad Española de Neumología y Cirugía Torácica (SEPAR; Barcelona, Spain) (Smoking Integrated Research Programme Call)

The symbiotic biofilm of Sinorhizobium fredii SMH12, necessary for successful colonization and symbiosis of glycine max cv osumi, is regulated by quorum sensing systems and inducing Flavonoids via NodD1

Bacterial surface components, especially exopolysaccharides, in combination with bacterial Quorum Sensing signals are crucial for the formation of biofilms in most species studied so far. Biofilm formation allows soil bacteria to colonize their surrounding habitat and survive common environmental stresses such as desiccation and nutrient limitation. This mode of life is often essential for survival in bacteria of the genera Mesorhizobium, Sinorhizobium, Bradyrhizobium, and Rhizobium. The role of biofilm formation in symbiosis has been investigated in detail for Sinorhizobium meliloti and Bradyrhizobium japonicum. However, for S. fredii this process has not been studied. In this work we have demonstrated that biofilm formation is crucial for an optimal root colonization and symbiosis between S. fredii SMH12 and Glycine max cv Osumi. In this bacterium, nod-gene inducing flavonoids and the NodD1 protein are required for the transition of the biofilm structure from monolayer to microcolony. Quorum Sensing systems are also required for the full development of both types of biofilms. In fact, both the nodD1 mutant and the lactonase strain (the lactonase enzyme prevents AHL accumulation) are defective in soybean root colonization. The impairment of the lactonase strain in its colonization ability leads to a decrease in the symbiotic parameters. Interestingly, NodD1 together with flavonoids activates certain quorum sensing systems implicit in the development of the symbiotic biofilm. Thus, S. fredii SMH12 by means of a unique key molecule, the flavonoid, efficiently forms biofilm, colonizes the legume roots and activates the synthesis of Nod factors, required for successfully symbiosis