Lipid Peroxides and α-Tocopherol in Rat Streptozotocin-Induced Diabetes Mellitus

Measurement of lipid peroxides and alpha-tocopherol was undertaken in rats with streptozotocin-induced diabetes. In sera and livers in diabetic rats, the lipid peroxides increased but alpha-tocopherol decreased. To study the effect of vitamin E deficiency in the diabetic state, diabetes was induced in rats maintained on a vitamin E deficient diet. Serum lipid peroxides increased greatly but alpha-tocopherol decreased. Lipid peroxides and alpha-tocopherol increased in the liver of vitamin E deficient states. In the liver, vitamin E deficient diabetic rats had lower lipid peroxides levels but higher alpha-tocopherol levels than vitamin E deficient non-diabetic rats. On the basis of the present experiments, it was considered that the decrease of alpha-tocopherol might be due to consumption as an antioxidant as lipid peroxides increased in sera and livers. The decrease of lipid peroxides in the liver was thought to play an important part of the increase in serum lipid peroxides.</p

Additional file 2: of Acceptability of healthcare interventions: an overview of reviews and development of a theoretical framework

References. Description of data: Citation details of all the systematic reviews included in the overview of reviews. (DOCX 40 kb

RBH : publication of the Associação Nacional de História - ANPUH

Transcripts of Video 1 and Video 2. (DOCX 20 kb

Additional file 1: of Improving appropriate polypharmacy for older people in primary care: selecting components of an evidence-based intervention to target prescribing and dispensing

General practitioner interview topic guide. TDF-based topic guide that was used to explore the theoretical domains as barriers and facilitators to the prescribing of appropriate polypharmacy for older people.(DOC 62 kb

Additional file 2: of A feasibility study of a theory-based intervention to improve appropriate polypharmacy for older people in primary care

Patient feedback questionnaire. (DOCX 50 kb

Additional file 1: of A feasibility study of a theory-based intervention to improve appropriate polypharmacy for older people in primary care

GP feedback questionnaire. (DOCX 66 kb

Additional file 1: Table S1. of The ethics of future trials: qualitative analysis of physicians’ decision making

Additional quotes. (PDF 178 kb

Additional file 1: of Intermittent auscultation versus continuous fetal monitoring: exploring factors that influence birthing unit nurses’ fetal surveillance practice using theoretical domains framework

Patey et al. fetal surveillance interview guide contains that Semi-structured interview guide, based on the TDF, used in this study. (PDF 149 kb

Additional file 1: of Barriers and enablers to diabetic retinopathy screening attendance: Protocol for a systematic review

Prisma-P Checklist. This checklist includes recommended items to address in a systematic reviews protocol and their location in this protocol. (PDF 60 kb

Additional file 6: of Barriers and facilitators to early rehabilitation in mechanically ventilated patients—a theory-driven interview study

Frequency of all Beliefs by Profession. (DOCX 29 kb