Vector Control Algorithm for Electric Vehicle AC Induction Motor Based on Improved Variable Gain PID Controller

The acceleration performance of EV, which affects a lot of performances of EV such as start-up, overtaking, driving safety, and ride comfort, has become increasingly popular in recent researches. An improved variable gain PID control algorithm to improve the acceleration performance is proposed in this paper. The results of simulation with Matlab/Simulink demonstrate the effectiveness of the proposed algorithm through the control performance of motor velocity, motor torque, and three-phase current of motor. Moreover, it is investigated that the proposed controller is valid by comparison with the other PID controllers. Furthermore, the AC induction motor experiment set is constructed to verify the effect of proposed controller

Combining high-throughput micro-CT-RGB phenotyping and genome-wide association study to dissect the genetic architecture of tiller growth in rice

Manual phenotyping of rice tillers is time consuming and labor intensive and lags behind the rapid development of rice functional genomics. Thus, automated, non-destructive phenotyping of rice tiller traits at a high spatial resolution and high-throughput for large-scale assessment of rice accessions is urgently needed. In this study, we developed a high-throughput micro-CT-RGB (HCR) imaging system to non-destructively extract 730 traits from 234 rice accessions at 9 time points. We could explain 30% of the grain yield variance from 2 tiller traits assessed in the early growth stages. A total of 402 significantly associated loci were identified by GWAS, and dynamic and static genetic components were found across the nine time points. A major locus associated with tiller angle was detected at nine time points, which contained a major gene TAC1. Significant variants associated with tiller angle were enriched in the 3'-UTR of TAC1. Three haplotypes for the gene were found and rice accessions containing haplotype H3 displayed much smaller tiller angles. Further, we found two loci contained associations with both vigor-related HCR traits and yield. The superior alleles would be beneficial for breeding of high yield and dense planting

Association between diabetes at different diagnostic ages and risk of cancer incidence and mortality: a cohort study

BackgroundDifferent ages for diagnosis of diabetes have diverse effects on risks of cardiovascular disease, dementia, and mortality, but there is little evidence of cancer. This study investigated the relationship between diabetes at different diagnostic ages and risks of cancer incidence and mortality in people aged 37–73 years.MethodsParticipants with diabetes in the UK Biobank prospective cohort were divided into four groups: ≤40, 41–50, 51–60, and >60 years according to age at diagnosis. A total of 26,318 diabetics and 105,272 controls (1:4 randomly selected for each diabetic matched by the same baseline age) were included. We calculated the incidence density, standardized incidence, and mortality rates of cancer. Cox proportional hazard model was used to examine the associations of diabetes at different diagnostic ages with cancer incidence and mortality, followed by subgroup analyses.ResultsCompared to corresponding controls, standardized incidence and mortality rates of overall and digestive system cancers were higher in diabetes diagnosed at age 41–50, 51–60, and >60 years, especially at 51–60 years. Individuals diagnosed with diabetes at different ages were at higher risk to develop site-specific cancers, with a prominently increased risk of liver cancer since the diagnosis age of >40 years. Significantly, participants with diabetes diagnosed at 51–60 years were correlated with various site-specific cancer risks [hazard ratio (HR) for incidence: 1.088–2.416, HR for mortality: 1.276–3.269]. Moreover, for mortality of digestive system cancers, we observed an interaction effect between smoking and diabetes diagnosed at 51–60 years.ConclusionOur findings highlighted that the age at diagnosis of diabetes, especially 51–60 years, was critical risks of cancer incidence and mortality and may represent a potential preventative window for cancer

Multinational patterns of second line antihyperglycaemic drug initiation across cardiovascular risk groups:federated pharmacoepidemiological evaluation in LEGEND-T2DM

Objective: To assess the uptake of second line antihyperglycaemic drugs among patients with type 2 diabetes mellitus who are receiving metformin.Design: Federated pharmacoepidemiological evaluation in LEGEND-T2DM.Setting: 10 US and seven non-US electronic health record and administrative claims databases in the Observational Health Data Sciences and Informatics network in eight countries from 2011 to the end of 2021.Participants: 4.8 million patients (≥18 years) across US and non-US based databases with type 2 diabetes mellitus who had received metformin monotherapy and had initiated second line treatments.Exposure: The exposure used to evaluate each database was calendar year trends, with the years in the study that were specific to each cohort.Main outcomes measures: The outcome was the incidence of second line antihyperglycaemic drug use (ie, glucagon-like peptide-1 receptor agonists, sodium-glucose cotransporter-2 inhibitors, dipeptidyl peptidase-4 inhibitors, and sulfonylureas) among individuals who were already receiving treatment with metformin. The relative drug class level uptake across cardiovascular risk groups was also evaluated.Results: 4.6 million patients were identified in US databases, 61 382 from Spain, 32 442 from Germany, 25 173 from the UK, 13 270 from France, 5580 from Scotland, 4614 from Hong Kong, and 2322 from Australia. During 2011-21, the combined proportional initiation of the cardioprotective antihyperglycaemic drugs (glucagon-like peptide-1 receptor agonists and sodium-glucose cotransporter-2 inhibitors) increased across all data sources, with the combined initiation of these drugs as second line drugs in 2021 ranging from 35.2% to 68.2% in the US databases, 15.4% in France, 34.7% in Spain, 50.1% in Germany, and 54.8% in Scotland. From 2016 to 2021, in some US and non-US databases, uptake of glucagon-like peptide-1 receptor agonists and sodium-glucose cotransporter-2 inhibitors increased more significantly among populations with no cardiovascular disease compared with patients with established cardiovascular disease. No data source provided evidence of a greater increase in the uptake of these two drug classes in populations with cardiovascular disease compared with no cardiovascular disease.Conclusions: Despite the increase in overall uptake of cardioprotective antihyperglycaemic drugs as second line treatments for type 2 diabetes mellitus, their uptake was lower in patients with cardiovascular disease than in people with no cardiovascular disease over the past decade. A strategy is needed to ensure that medication use is concordant with guideline recommendations to improve outcomes of patients with type 2 diabetes mellitus.</p

The New Urbanism as a theory and its contemporary application in China -----Redesign a residential project in Beijing

The New Urbanism is one of the most influential planning movements since the late 20th century. The planning ideas and successful projects of New Urbanism are leading us to pursue the better living conditions. Under the influence of globalization, as the world’s fastest growing countries, the urban construction of China inevitably affected by the impact of new ideas. Meanwhile, during the process of construction emerged some urban problems. In the growing process of urbanization and suburbanization, the planning of Chinese residential areas still remain the mode of function division and sprawl development. Therefore, the application of advanced new ideas to improve the planning of Chinese residential area is well worth researching. This paper starts with issues about Chinese contemporary residential community planning, and then confirms the research question. After that, this paper introduces the related concepts to define the objects of research. Through the theoretical study, extract the New Urbanism community design concepts. And then, analysis the design concepts, study three practical cases of New Urbanism residential community and two cases of Chinese residential community, combining with the site observation, summarize the possibilities and opportunity of residential community planning in China. Meanwhile, proposed the planning ideas, which is on the basis of the research before, and design a proposal in Beijing to implement the research question. Finally, evaluate the proposal and clarify the research result, points out the problems that need further investigation

The New Urbanism as a theory and its contemporary application in China -----Redesign a residential project in Beijing

The New Urbanism is one of the most influential planning movements since the late 20th century. The planning ideas and successful projects of New Urbanism are leading us to pursue the better living conditions. Under the influence of globalization, as the world’s fastest growing countries, the urban construction of China inevitably affected by the impact of new ideas. Meanwhile, during the process of construction emerged some urban problems. In the growing process of urbanization and suburbanization, the planning of Chinese residential areas still remain the mode of function division and sprawl development. Therefore, the application of advanced new ideas to improve the planning of Chinese residential area is well worth researching. This paper starts with issues about Chinese contemporary residential community planning, and then confirms the research question. After that, this paper introduces the related concepts to define the objects of research. Through the theoretical study, extract the New Urbanism community design concepts. And then, analysis the design concepts, study three practical cases of New Urbanism residential community and two cases of Chinese residential community, combining with the site observation, summarize the possibilities and opportunity of residential community planning in China. Meanwhile, proposed the planning ideas, which is on the basis of the research before, and design a proposal in Beijing to implement the research question. Finally, evaluate the proposal and clarify the research result, points out the problems that need further investigation