Unequal Error Protected JPEG 2000 Broadcast Scheme with Progressive Fountain Codes

This paper proposes a novel scheme, based on progressive fountain codes, for broadcasting JPEG 2000 multimedia. In such a broadcast scheme, progressive resolution levels of images/video have been unequally protected when transmitted using the proposed progressive fountain codes. With progressive fountain codes applied in the broadcast scheme, the resolutions of images (JPEG 2000) or videos (MJPEG 2000) received by different users can be automatically adaptive to their channel qualities, i.e. the users with good channel qualities are possible to receive the high resolution images/vedio while the users with bad channel qualities may receive low resolution images/vedio. Finally, the performance of the proposed scheme is evaluated with the MJPEG 2000 broadcast prototype

Rateless Codes with Progressive Recovery for Layered Multimedia Delivery

This paper proposes a novel approach, based on unequal error protection, to enhance rateless codes with progressive recovery for layered multimedia delivery. With a parallel encoding structure, the proposed Progressive Rateless codes (PRC) assign unequal redundancy to each layer in accordance with their importance. Each output symbol contains information from all layers, and thus the stream layers can be recovered progressively at the expected received ratios of output symbols. Furthermore, the dependency between layers is naturally considered. The performance of the PRC is evaluated and compared with some related UEP approaches. Results show that our PRC approach provides better recovery performance with lower overhead both theoretically and numerically

Abstracts from the NIHR INVOLVE Conference 2017

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Design and baseline characteristics of the finerenone in reducing cardiovascular mortality and morbidity in diabetic kidney disease trial

Background: Among people with diabetes, those with kidney disease have exceptionally high rates of cardiovascular (CV) morbidity and mortality and progression of their underlying kidney disease. Finerenone is a novel, nonsteroidal, selective mineralocorticoid receptor antagonist that has shown to reduce albuminuria in type 2 diabetes (T2D) patients with chronic kidney disease (CKD) while revealing only a low risk of hyperkalemia. However, the effect of finerenone on CV and renal outcomes has not yet been investigated in long-term trials. Patients and Methods: The Finerenone in Reducing CV Mortality and Morbidity in Diabetic Kidney Disease (FIGARO-DKD) trial aims to assess the efficacy and safety of finerenone compared to placebo at reducing clinically important CV and renal outcomes in T2D patients with CKD. FIGARO-DKD is a randomized, double-blind, placebo-controlled, parallel-group, event-driven trial running in 47 countries with an expected duration of approximately 6 years. FIGARO-DKD randomized 7,437 patients with an estimated glomerular filtration rate >= 25 mL/min/1.73 m(2) and albuminuria (urinary albumin-to-creatinine ratio >= 30 to <= 5,000 mg/g). The study has at least 90% power to detect a 20% reduction in the risk of the primary outcome (overall two-sided significance level alpha = 0.05), the composite of time to first occurrence of CV death, nonfatal myocardial infarction, nonfatal stroke, or hospitalization for heart failure. Conclusions: FIGARO-DKD will determine whether an optimally treated cohort of T2D patients with CKD at high risk of CV and renal events will experience cardiorenal benefits with the addition of finerenone to their treatment regimen. Trial Registration: EudraCT number: 2015-000950-39; ClinicalTrials.gov identifier: NCT02545049

<it>K</it>-cluster-valued compressive sensing for imaging

<p>Abstract</p> <p>The success of compressive sensing (CS) implies that an image can be compressed directly into acquisition with the measurement number over the whole image less than pixel number of the image. In this paper, we extend the existing CS by including the prior knowledge of <it>K</it>-cluster values available for the pixels or wavelet coefficients of an image. In order to model such prior knowledge, we propose in this paper <it>K</it>-cluster-valued CS approach for imaging, by incorporating the <it>K</it>-means algorithm in CoSaMP recovery algorithm. One significant advantage of the proposed approach, rather than the conventional CS, is the capability of reducing measurement numbers required for the accurate image reconstruction. Finally, the performance of conventional CS and <it>K</it>-cluster-valued CS is evaluated using some natural images and background subtraction images.</p

Markerless Kinect-Based Hand Tracking for Robot Teleoperation

This paper presents a real-time remote robot teleoperation method using markerless Kinect-based hand tracking. Using this tracking algorithm, the positions of index finger and thumb in 3D can be estimated by processing depth images from Kinect. The hand pose is used as a model to specify the pose of a real-time remote robot's end-effector. This method provides a way to send a whole task to a remote robot instead of sending limited motion commands like gesture-based approaches and this method has been tested in pick-and-place tasks

Minimal Residual Disease Detection and Evolved IGH Clones Analysis in Acute B Lymphoblastic Leukemia Using IGH Deep Sequencing

Acute B lymphoblastic leukemia (B-ALL) is one of most common types of childhood cancer worldwide and chemotherapy is the main treatment approach. Despite good response rates to chemotherapy regiments, many patients eventually relapse and minimal residual disease (MRD) is the leading risk factor for relapse. The evolution of leukemic clones during disease development and treatment may have clinical significance. In this study, we performed immunoglobulin heavy chain (IGH) repertoire high throughput sequencing (HTS) on the diagnostic and post-treatment samples of 51 pediatric B-ALL patients. We identified leukemic IGH clones in 92.2% of the diagnostic samples and nearly half of the patients were polyclonal. About 1/3 of the leukemic clones have correct open reading frame (ORF) in the complementarity determining region 3 (CDR3) of IGH, which demonstrates that the leukemic B cells were in the early developmental stage. We also demonstrated the higher sensitivity of HTS in MRD detection and investigated the clinical value of using peripheral blood in MRD detection and monitoring the clonal IGH evolution. In addition, we found leukemic clones were extensively undergoing continuous clonal IGH evolution by variable gene replacement. Dynamic frequency change and newly emerged evolved IGH clones were identified upon the pressure of chemotherapy. In summary, we confirmed the high sensitivity and universal applicability of HTS in MRD detection. We also reported the ubiquitous evolved IGH clones in B-ALL samples and their response to chemotherapy during treatment