Entanglement witness and entropy uncertainty of open Quantum systems under Zeno effect

The entanglement witness and the entropy uncertainty are investigated by using the pseudomode theory for the open two-atom system under the quantum Zeno effect. The results show that, only when the two spectrums satisfy strong coupling with the atom, the time of entanglement witness can be prolonged and the lower bound of the entropic uncertainty can be reduced, and the entanglement can be witnessed many times. We also gave the corresponding physical explanation by the non-Markovianity. The Zeno effect not only can very effectively prolong the time of entanglement witness and reduce the lower bound of the entropy uncertainty, but also can greatly enhance the time of entanglement witness and reduce the entanglement value of witness

The virulence factor regulator and quorum sensing regulate the type I-F CRISPR-Cas mediated horizontal gene transfer in Pseudomonas aeruginosa

Pseudomonas aeruginosa is capable of thriving in diverse environments due to its network of regulatory components for effective response to stress factors. The survival of the bacteria is also dependent on the ability to discriminate between the acquisition of beneficial and non-beneficial genetic materials via horizontal gene transfer (HGT). Thus, bacteria have evolved the CRISPR-Cas adaptive immune system for defense against the deleterious effect of phage infection and HGT. By using the transposon mutagenesis approach, we identified the virulence factor regulator (Vfr) as a key regulator of the type I-F CRISPR-Cas system in P. aeruginosa. We showed that Vfr influences the expression of the CRISPR-Cas system through two signaling pathways in response to changes in calcium levels. Under calcium-rich conditions, Vfr indirectly regulates the CRISPR-Cas system via modulation of the AHL-QS gene expression, which could be vital for defense against phage infection at high cell density. When encountering calcium deficiency, however, Vfr can directly regulate the CRISPR-Cas system via a cAMP-dependent pathway. Furthermore, we provide evidence that mutation of vfr reduces the CRISPR-Cas spacer acquisition and interference of HGT. The results from this study add to the regulatory network of factors controlling the CRISPR-Cas system in response to abiotic factors in the environment. The findings may facilitate the design of effective and reliable phage therapies against P. aeruginosa infections, as targeting Vfr could prevent the development of the CRISPR-Cas mediated phage resistance

Optimal Hybrid Beamforming Design for Millimeter-Wave Massive Multi-User MIMO Relay Systems

As a promising technology in the next generation mobile network, millimeter-wave (mmWave) communication can mitigate the spectrum crunch of improving the network capacity by exploiting the large underutilized spectrum bands of the mmWave frequencies. The hybrid (analog/digital) beamforming of multi-data streams are widely used to further the spectrum efficiency of mmWave relay system when faced with the complex environment or long distance communication. This paper investigates the hybrid beamforming scheme for the decode-and-forward (DF) mmWave massive multiple-input multiple-output (MIMO) relay system with mixed structure and full-connected structure. We optimize hybrid beamforming of relay system by maximizing the sum rate of the overall system as an objective function. To reduce the computational complexity, we reformulate the original problem as two single-hop mmWave MIMO sum-rate maximization subproblems. Then, the piecewise successive approximation method is proposed based on the criterion which jointly designs the analog and digital beamforming stages by trying to avoid the loss of information at each stage. The hybrid beamforming of the two subproblems can be solved by the proposed scheme united with the idea of successive interference cancelation (SIC), the baseband block diagonalization (BD) scheme, and waterfilling power allocation method. Finally, simulation results confirm that the proposed optimal method can achieve good performance in hybrid beamforming design of relay system with both mixed and full-connected structures

Efficient Hybrid Beamforming Design in mmWave Massive MU-MIMO DF Relay Systems with the Mixed-Structure

In this paper, we consider the decode-and-forward (DF) relay system in millimeter-wave (mmWave) massive multiple-input multiple-output (MIMO) systems, and propose a hybrid beamforming design method for the mixed structure, which contains the fully-connected and sub-connected structures. To satisfy constant-modulus and block-diagonalization (BD) constraints, the analog beamforming is designed by the idea of sorted successive interference cancellation (SSIC). More specifically, the proposed method first sorts the capacities of different analog sub-channels in descending order, and then designs the analog beamforming serially according to the order of the capacities. To efficiently mitigate the inner-user and inter-user interference, we propose a modified baseband BD technology to reduce the information loss in digital beamforming design, thereby improving the system capacity. In addition, the proposed hybrid beamforming algorithm is designed by considering both uniform linear arrays (ULAs) and uniform planar arrays (UPAs). Simulation results demonstrate that the proposed hybrid beamforming design scheme can obtain good performance in terms of the achievable sum-rate and power efficiency in ULAs and UPAs