Construction of Trust Relationship between Doctors and Patients: A Social Psychological Analysis

Doctor-patient trust is the basis of harmonious doctor-patient relationship. Social psychology plays a unique role in interpreting the connotation and construction of doctor-patient trust relationship. From the two levels of doctor-patient interpersonal trust and intergroup trust, this paper summarizes the relevant theoretical viewpoints of social psychology on the construction of doctor-patient trust relationship, and analyzes the key factors affecting doctor-patient interpersonal trust and intergroup trust. On this basis, this paper puts forward the construction path of doctor-patient trust of “interpersonal interaction-emotional communication-interpersonal trust” and “intergroup interaction-social knowledge-intergroup trust”, reveals the interaction mechanism of interpersonal trust and intergroup trust and the circular feedback mechanism between them to promote the formation of doctor-patient trust relationship, and establishes a social psychology model of the formation mechanism of doctor-patient trust relationship

Studi Pengetahuan Tentang Menstruasi Dengan Upaya Penanganan Dismenore Pada Mahasiswa Pendidikan Biologi

. Dysmenorrhea is a condition of pain during menstruation experienced by women. There are heavy and light of menstruation pain, knowledge of menstruation disorder will determine of the dysmenorrhea holding efforts. The purpose of this study was to determine the relationship of knowledge about menstruation and dysmenorrhea holding efforts. The population of this study was all students of Biology Education 6th semester who are taking the course of Human Anatomy and Physiology, while samples were taken by purposive sampling, with the criteria of female students who experience dysmenorrhea. Data of knowledge about menstruation collected by a multiple choice test, whereas the holding of dysmenorrhea collected using questionnaires. Furthermore, the relationship of knowledge of menstruation and the holding of dysmenorrhea was analyzed by Product Moment. The results showed that the students with good knowledge of menstruation were 72.7%, insufficient knowledge were 27.3% and less knowledge were 0%. Dysmenorrhea treatment efforts are chosen by the students are varied, students who choose to pharmacological and non-pharmacological simultaneously is 2 ( 6.06% ) , non-pharmacological means only 31 people ( 93.94 % ) . Product moment correlation test results obtained rcount = 0.014 < rtable 0.05: 33 = 0.344, meaning there is no relationship between student knowledge about menstruation and preventing dysmenorrhea . The conclusion of this study are : a) the student\u27s knowledge about menstruation mostly categorized as good , b ) The handling of dysmenorrhea by students mostly by way of non-pharmacological; c ). Student knowledge about menstruation does not specify the handling of dysmenorrhe

Genetic and functional characterization of disease associations explains comorbidity

Understanding relationships between diseases, such as comorbidities, has important socio-economic implications, ranging from clinical study design to health care planning. Most studies characterize disease comorbidity using shared genetic origins, ignoring pathway-based commonalities between diseases. In this study, we define the disease pathways using an interactome-based extension of known disease-genes and introduce several measures of functional overlap. The analysis reveals 206 significant links among 94 diseases, giving rise to a highly clustered disease association network. We observe that around 95% of the links in the disease network, though not identified by genetic overlap, are discovered by functional overlap. This disease network portraits rheumatoid arthritis, asthma, atherosclerosis, pulmonary diseases and Crohn's disease as hubs and thus pointing to common inflammatory processes underlying disease pathophysiology. We identify several described associations such as the inverse comorbidity relationship between Alzheimer's disease and neoplasms. Furthermore, we investigate the disruptions in protein interactions by mapping mutations onto the domains involved in the interaction, suggesting hypotheses on the causal link between diseases. Finally, we provide several proof-of-principle examples in which we model the effect of the mutation and the change of the association strength, which could explain the observed comorbidity between diseases caused by the same genetic alterations

A Genome Wide Association Study Identifies Common Variants Associated with Lipid Levels in the Chinese Population

Plasma lipid levels are important risk factors for cardiovascular disease and are influenced by genetic and environmental factors. Recent genome wide association studies (GWAS) have identified several lipid-associated loci, but these loci have been identified primarily in European populations. In order to identify genetic markers for lipid levels in a Chinese population and analyze the heterogeneity between Europeans and Asians, especially Chinese, we performed a meta-analysis of two genome wide association studies on four common lipid traits including total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL) and high-density lipoprotein cholesterol (HDL) in a Han Chinese population totaling 3,451 healthy subjects. Replication was performed in an additional 8,830 subjects of Han Chinese ethnicity. We replicated eight loci associated with lipid levels previously reported in a European population. The loci genome wide significantly associated with TC were near DOCK7, HMGCR and ABO; those genome wide significantly associated with TG were near APOA1/C3/A4/A5 and LPL; those genome wide significantly associated with LDL were near HMGCR, ABO and TOMM40; and those genome wide significantly associated with HDL were near LPL, LIPC and CETP. In addition, an additive genotype score of eight SNPs representing the eight loci that were found to be associated with lipid levels was associated with higher TC, TG and LDL levels (P = 5.52×10-16, 1.38×10-6 and 5.59×10-9, respectively). These findings suggest the cumulative effects of multiple genetic loci on plasma lipid levels. Comparisons with previous GWAS of lipids highlight heterogeneity in allele frequency and in effect size for some loci between Chinese and European populations. The results from our GWAS provided comprehensive and convincing evidence of the genetic determinants of plasma lipid levels in a Chinese population

Endovascular treatment of acute ischemic stroke with a fully radiopaque retriever: A randomized controlled trial

ObjectiveThe Neurohawk retriever is a new fully radiopaque retriever. A randomized controlled non-inferiority trial was conducted to compare the Neurohawk and the Solitaire FR in terms of safety and efficacy. In order to evaluate the efficacy and safety of endovascular treatment in acute ischemic stroke (AIS) caused by intracranial atherosclerotic disease (ICAD) larger vessel occlusion (LVO), a sub-analysis was performed.MethodsAcute ischemic stroke patients aged 18–80 years with LVO in the anterior circulation were randomly assigned to undergo thrombectomy with either the Neurohawk or the Solitaire FR. The primary efficacy endpoint was successful reperfusion (mTICI 2b-3) rate by the allocated retriever. A relevant non-inferiority margin was 12.5%. Safety outcomes were symptomatic intracranial hemorrhage (sICH) and all-cause mortality within 90 days. Secondary endpoints included first-pass effect (FPE), modified FPE, and favorable outcomes at 90 days. In subgroup analysis, the patients were divided into the ICAD group and non-ICAD group according to etiology, and baseline characteristics, angiographic, and clinical outcomes were compared.ResultsA total of 232 patients were involved in this analysis (115 patients in the Neurohawk group and 117 in the Solitaire group). The rates of successful reperfusion with the allocated retriever were 88.70% in the Neurohawk group and 90.60% in the Solitaire group (95%CI of the difference, −9.74% to 5.94%; p = 0.867). There were similar results in FPE and mFPE in both groups. The rate of sICH seemed higher in the Solitaire group (13.16% vs. 7.02%, p = 0.124). All-cause mortality and favorable outcome rates were comparable as well. In subgroup analysis, 58 patients were assigned to the ICAD group and the remaining 174 to the non-ICAD group. The final successful reperfusion and favorable outcome rates showed no statistically significant differences in two groups. Mortality within 90 days was relatively lower in the ICAD group (6.90% vs. 17.24%; p = 0.054).ConclusionThe Neurohawk retriever is non-inferior to the Solitaire FR in the mechanical thrombectomy of large vessel occlusion-acute ischemic stroke (LVO-AIS). The sub-analysis suggested that endovascular treatment including thrombectomy with the retriever and essential rescue angioplasty is effective and safe in AIS patients with intracranial atherosclerotic disease-larger vessel occlusion (ICAD-LVO).Clinical trial registrationhttps://clinicaltrials.gov/ct2/show/NCT04995757, number: NCT04995757

Phase-matched second-harmonic generation in bulk azodye-doped polymers by all-optical poling

We demonstrate phase-matched second-harmonic generation (SHG) in bulk azodye-doped polymethylmethacrylate using an all-optical poling technique. During the seeding process, samples were irradiated simultaneously by coherent superposition of the fundamental and the second-harmonic light of a nanosecond laser. The measurements for the dependence of SHG on the sample thickness show that the SHG signals increase with the increase in thickness of the samples, indicating that a χ(2)grating that satisfies the phase-matching condition for SHG could be optically induced in the polymer samples

Opportunistic Packet Scheduling and Media Access Control for Wireless LANs and Multi-hop Ad Hoc Networks

In the wireless LANs or mobile ad hoc networks, a node with multi-packets in its queue waiting for delivery to several neighboring nodes may choose to schedule a candidate receiver with good channel condition for transmission. By choosing a receiver with good channel condition, the Head-of-Line (HOL) blocking problem can be alleviated and the overall system throughput can be increased. Motivated by this observation, we introduce the Opportunistic packet Scheduling and Media Access control (OSMA) protocol to exploit high quality channel condition under certain fairness constraints. We base our design on CSMA/CA so that it can be simply incorporated into the 802.11 standard.The key mechanisms of OSMA protocol are multicast RTS and priority-based CTS. In the OSMA protocol, RTS includes a list of candidate receivers. Among those who are qualified to receive data, the one with the highest order would be granted to catch the channel by replying CTS in the first place. The ordering list will be updated dynamically according to certain scheduling policy such as Round Robin (RR) and Earlier timestamp First (ETF), so other performance metrics, e.x., fairness and timeliness, can be enhanced. To the best of our knowledge, this is the first paper to exploit the multiuser diversity in the CSMA/CA based wireless networks. We evaluate the OSMA using ns-2 and our simulation results show that this protocol can improve the network throughput significantly