65 research outputs found

    El ingenierismo cambiario. La peseta en los años del cambio múltiple, 1948-1959

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    Editada en la Fundación Empresa PúblicaEl sistema de cambios múltiples para la peseta, vigente desde 1948 a 1959, ha planteado numerosos problemas a la historiografia española, pues implica desco nocer el precio al que se hacían las operaciones exterior, enmascarado en la fronda de cambios especiales. En el presente trabajo se estima la serie de los diversos tipos de cambio promedio de toda la Balanza de pagos en el periodo, cubriendo el vacio que la posguerra representaba en la historia de la peseta. Ademas se calcula el tipo de cambio efectivo real, para concluir que las importantes devaluaciones de 1949-51 y 1957-59 fueron insuficientes para alcanzar el equilibrio entre los precios relativos de España y sus principales socios comerciales por lo que la peseta se mantuvo sobrevalorada de forma continua a lo largo de los cuarenta y cincuenta.The system of multiple exchange rates for the peseta, in force between 1948 and 1959, has posed many problems for Spanish historiography, in that it implies that the price at wich foreing transactions were carried out is unknown, being hidden in the dense foliage os special exchange rates. In this paper we estimate the various average exchange rates series for all the Balance of Payments of these years, thus filling the vacuum that the post-Civil War period represents in the history of the peseta. We also calculate the real effective exchange rate, concluding that the important devaluations of 1949-1951 and 1957-1959 were insufficient in order to achieve equilibrium between Spanish relative prices and those of its main traiding partners, so that the peseta remained continuously over-valued throughout the 1940´s and 1950´sPublicad

    Reply to the comment by A. G. Jones et al. on “Deep resistivity cross section of the intraplate Atlas Mountains (NW Africa): new evidence of anomalous mantle and related Quaternary volcanism"

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    Scientific discussion and different points of view are a basis of the advancement of knowledge. We acknowledge the comments of Jones et al. [2012] as an opportunity to publicly discuss the structure and origin of the Atlas Mountains. Moreover, we welcome the opportunity to compare our results with those recently published by the group responsible for the comment [Ledo et al., 2011], although it is not pertinent to comment in detail on a paper published in another journal. We also wish to remark that the paper of Ledo et al. [2011] was reviewed and published during the revision period of our contribution [Anahnah et al., 2011]; therefore, they are two different approaches and data sets, measured in different sites and by different instruments for the same region, lending readers the chance to compare different interpretations. The main differences on the data sets are: the profile of Anahnah et al. [2011] compared with the profile of Ledo et al. [2011] is 170 km longer, vertical magnetic data were obtained and lower frequencies were recordedDepartamento de Geodinámica, Universidad de Granada, EspañaInstituto Andaluz de Ciencias de la Tierra, Consejo Superior de Investigaciones Científicas, EspañaInstituto Andaluz de Ciencias de la Tierra, Universidad de Granada, EspañaDépartement de Géologie, Université Mohammed V, MarruecosUnidad de Granada, Instituto Geológico y Minero de España, EspañaDepartament de Geodinàmica i Geofísica, Universitat de Barcelona, EspañaInstitute of Geological & Nuclear Sciences Limited, Nueva ZelandaGéosciences Montpellier, Université Montpellier, FranciaDépartement de Géologie, Université Abdelmalek Esaadi, MarruecosCentro de Geociencias, Universidad Nacional Autónoma de México, Méxic

    Newborns and low to moderate prenatal environmental lead exposure: Might fathers be the key?

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    This study is part of the BioMadrid Project, a bio-monitoring study designed to assess pollutants in the environment surrounding children born in the Madrid region. Our aim in this report is to evaluate the association between prenatal lead exposure and fetal development using three biological samples (maternal and paternal blood lead at around 34 weeks of gestation as well as cord blood lead levels), three biomarkers of effect in cord blood peripheral lymphocytes (micronucleus in binucleated cells, nucleoplasmic bridges, and nuclear buds), and different anthropometrical characteristics at birth. Maternal and cord blood lead were not associated with newborn measurements or genotoxicity biomarkers. In contrast, increases in father blood lead were coupled with lower weight (mean difference (MD), -110.8 g; 95% confidence intervals (95%CI), -235.6 to 6.00; p < 0.10) and shorter abdominal (MD, -0.81 cm; 95%CI, -1.64 to 0.00; p < 0.05) and cephalic (MD, -0.32 cm; 95%CI, -0.65 to 0.00; p < 0.05) circumferences at birth as well as with the presence of nucleoplasmic bridges (odds ratio, 1.03; 95%CI, 1.00 to 1.06; p < 0.05) and nuclear buds (odds ratio, 1.02; 95%CI, 0.99 to 1.04; p < 0.10). These associations were mainly confined to female babies, in whom paternal lead was also inversely associated with length. Our results support the hypothesis that paternal lead exposure may be affecting the development of newborns.Financial support was obtained from the Madrid Regional Health and Consumer Affairs Authority and the Spanish Health Research Fund (Fondo de Investigación Sanitaria (FIS) grant PI040777). Dr. Esther Garcia-Esquinas was supported by a Río Hortega (CM10/00332) research training grant from the Spanish Ministry of Economy and Competitiveness (Carlos III Institute of Health) and by the Enrique Nájera predoctoral grant awarded by the Spanish Society of Epidemiology and funded by the National School of Public Health.Peer reviewe

    Mercury, lead and cadmium in human milk in relation to diet, lifestyle habits and sociodemographic variables in Madrid (Spain)

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    [Background]: Although breastfeeding is the ideal way of nurturing infants, it can be a source of exposure to toxicants. This study reports the concentration of Hg, Pb and Cd in breast milk from a sample of women drawn from the general population of the Madrid Region, and explores the association between metal levels and socio-demographic factors, lifestyle habits, diet and environmental exposures, including tobacco smoke, exposure at home and occupational exposures.[Methods]: Breast milk was obtained from 100 women (20 mL) at around the third week postpartum. Pb, Cd and Hg levels were determined using Atomic Absorption Spectrometry. Metal levels were log-transformed due to non-normal distribution. Their association with the variables collected by questionnaire was assessed using linear regression models. Separate models were fitted for Hg, Pb and Cd, using univariate linear regression in a first step. Secondly, multivariate linear regression models were adjusted introducing potential confounders specific for each metal. Finally, a test for trend was performed in order to evaluate possible dose-response relationships between metal levels and changes in variables categories.[Results]: Geometric mean Hg, Pb and Cd content in milk were 0.53 μg L(-1), 15.56 μg L(-1), and 1.31 μg L(-1), respectively. Decreases in Hg levels in older women and in those with a previous history of pregnancies and lactations suggested clearance of this metal over lifetime, though differences were not statistically significant, probably due to limited sample size. Lead concentrations increased with greater exposure to motor vehicle traffic and higher potato consumption. Increased Cd levels were associated with type of lactation and tended to increase with tobacco smoking.[Conclusions]: Surveillance for the presence of heavy metals in human milk is needed. Smoking and dietary habits are the main factors linked to heavy metal levels in breast milk. Our results reinforce the need to strengthen national food safety programs and to further promote avoidance of unhealthy behaviors such as smoking during pregnancy.Peer reviewe

    Management of acute diverticulitis with pericolic free gas (ADIFAS). an international multicenter observational study

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    Background: There are no specific recommendations regarding the optimal management of this group of patients. The World Society of Emergency Surgery suggested a nonoperative strategy with antibiotic therapy, but this was a weak recommendation. This study aims to identify the optimal management of patients with acute diverticulitis (AD) presenting with pericolic free air with or without pericolic fluid. Methods: A multicenter, prospective, international study of patients diagnosed with AD and pericolic-free air with or without pericolic free fluid at a computed tomography (CT) scan between May 2020 and June 2021 was included. Patients were excluded if they had intra-abdominal distant free air, an abscess, generalized peritonitis, or less than a 1-year follow-up. The primary outcome was the rate of failure of nonoperative management within the index admission. Secondary outcomes included the rate of failure of nonoperative management within the first year and risk factors for failure. Results: A total of 810 patients were recruited across 69 European and South American centers; 744 patients (92%) were treated nonoperatively, and 66 (8%) underwent immediate surgery. Baseline characteristics were similar between groups. Hinchey II-IV on diagnostic imaging was the only independent risk factor for surgical intervention during index admission (odds ratios: 12.5, 95% CI: 2.4-64, P =0.003). Among patients treated nonoperatively, at index admission, 697 (94%) patients were discharged without any complications, 35 (4.7%) required emergency surgery, and 12 (1.6%) percutaneous drainage. Free pericolic fluid on CT scan was associated with a higher risk of failure of nonoperative management (odds ratios: 4.9, 95% CI: 1.2-19.9, P =0.023), with 88% of success compared to 96% without free fluid ( P &lt;0.001). The rate of treatment failure with nonoperative management during the first year of follow-up was 16.5%. Conclusion: Patients with AD presenting with pericolic free gas can be successfully managed nonoperatively in the vast majority of cases. Patients with both free pericolic gas and free pericolic fluid on a CT scan are at a higher risk of failing nonoperative management and require closer observation

    Role of age and comorbidities in mortality of patients with infective endocarditis

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    [Purpose]: The aim of this study was to analyse the characteristics of patients with IE in three groups of age and to assess the ability of age and the Charlson Comorbidity Index (CCI) to predict mortality. [Methods]: Prospective cohort study of all patients with IE included in the GAMES Spanish database between 2008 and 2015.Patients were stratified into three age groups:<65 years,65 to 80 years,and ≥ 80 years.The area under the receiver-operating characteristic (AUROC) curve was calculated to quantify the diagnostic accuracy of the CCI to predict mortality risk. [Results]: A total of 3120 patients with IE (1327 < 65 years;1291 65-80 years;502 ≥ 80 years) were enrolled.Fever and heart failure were the most common presentations of IE, with no differences among age groups.Patients ≥80 years who underwent surgery were significantly lower compared with other age groups (14.3%,65 years; 20.5%,65-79 years; 31.3%,≥80 years). In-hospital mortality was lower in the <65-year group (20.3%,<65 years;30.1%,65-79 years;34.7%,≥80 years;p < 0.001) as well as 1-year mortality (3.2%, <65 years; 5.5%, 65-80 years;7.6%,≥80 years; p = 0.003).Independent predictors of mortality were age ≥ 80 years (hazard ratio [HR]:2.78;95% confidence interval [CI]:2.32–3.34), CCI ≥ 3 (HR:1.62; 95% CI:1.39–1.88),and non-performed surgery (HR:1.64;95% CI:11.16–1.58).When the three age groups were compared,the AUROC curve for CCI was significantly larger for patients aged <65 years(p < 0.001) for both in-hospital and 1-year mortality. [Conclusion]: There were no differences in the clinical presentation of IE between the groups. Age ≥ 80 years, high comorbidity (measured by CCI),and non-performance of surgery were independent predictors of mortality in patients with IE.CCI could help to identify those patients with IE and surgical indication who present a lower risk of in-hospital and 1-year mortality after surgery, especially in the <65-year group
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