Effects of A17924G Genotypes Associated with Thioesterase Domain of Fatty Acid Synthase and K232A Genotypes of Diacylglycerol Acyltransferase-1 on Milk Fatty Acid Composition in Holstein Dairy Cows

The objective of this study was to determine if variations in single nucleotide polymorphism (SNP) in thioesterase domain of the fatty acid synthase (g.17924 A\u3eG Threonine\u3eAlanine) and in diacylglycerol acyltransferase-1 (g.10433/10434 GC/AA Alanine\u3eLysine) genes would explain variations in milk fatty acid composition among Holstein dairy cattle. About 200 cows participated in the study. Milk samples were collected monthly throughout the first ten months of lactation and analyzed for milk fatty acid composition by gas chromatography. Blood samples were used to obtain a DNA sample for each animal. Milk from cows with g.17924GG genotype had lower atherogenic index [AI; (12:0 + 4(14:0) + 16:0)/(MUFA + PUFA)] compared with milk from cows of g.17924AG genotype (P=0.007). Likewise, milk from cows with p.232AA genotype had lower AI compared with that from cows of p.232KK genotype (P\u3c0.016). The decrease in AI for cows with g.17924GG and p.232AA genotypes was achieved by the decrease in the concentration of palmitic acid (P=0.06 and P\u3c0.0001, respectively) and by the increase in the concentration of mono- and polyunsaturated fatty acids in milk for both genotypes. The results of this study indicate the potential of using earlier mentioned SNPs as DNA markers to select breeding animals that produce progeny with a healthier milk fatty acid composition

Heritability Estimates for Fatty Acid Concentration in Angus Beef

Our group has previously reported that percentage of fatty acids within the total fatty acids shows evidence of being under genetic control. In more recent work, we are conducting a comparison of heritability estimates when the fatty acids are expressed as a percentage of the lipid (% fatty acid within the total fatty acids) or expressed as a concentration within the beef (mg fatty acid/g of beef). Expression of fatty acid concentration as mg fatty acid/g of beef is dependent upon both the concentration of lipid in the beef and the concentration of fatty acid within the lipid

Dual-mode regulation of the APC/C by CDK1 and MAPK controls meiosis I progression and fidelity

Dernière mise à jour : 26 août 2015 Il existe plusieurs enregistrements de cette chanson gaillarde de Saint-Gelais, notamment mise en musique par Pierre Certon et Clément Janequin. Parmi ceux-ci, Jacques Feuillie Vocal Group, Libertine songs of the French Renaissance, 1975. Le verger de musique, Antony Auvidis, 1999 (1996). Joël Cohen and The Boston Camerata, Pierre Certon : chansons, Harmonia Mundi, 2008 (1980). Württembergischer Kammerchor, Kurz Dieter, Trink- und Liebeslieder der Renaissa..

Impact of Hydrological Modellers’ Decisions and Attitude on the Performance of a Calibrated Conceptual Catchment Model: Results from a ‘Modelling Contest’

In this study, 17 hydrologists with different experience in hydrological modelling applied the same conceptual catchment model (HBV) to a Greek catchment, using identical data and model code. Calibration was performed manually. Subsequently, the modellers were asked for their experience, their calibration strategy, and whether they enjoyed the exercise. The exercise revealed that there is considerable modellers’ uncertainty even among the experienced modellers. It seemed to be equally important whether the modellers followed a good calibration strategy, and whether they enjoyed modelling. The exercise confirmed previous studies about the benefit of model ensembles: Different combinations of the simulation results (median, mean) outperformed the individual model simulations, while filtering the simulations even improved the quality of the model ensembles. Modellers’ experience, decisions, and attitude, therefore, have an impact on the hydrological model application and should be considered as part of hydrological modelling uncertainty