What do employers want from an aligned employment and skills system?: A report of research carried out by Ipsos MORI on behalf of the Department for Work and Pensions and the Department for Business, Innovation and Skills (Research paper number 41)

This document is related to http://dera.ioe.ac.uk/3011

What do employers want from an aligned employment and skills system? (Research report no. 743)

A report of research carried out by Ipsos MORI on behalf of the Department for Work and Pension

The Future of Health Care in New Brunswick: An Interview with Dr. Dennis Furlong

Dr. Dennis Furlong is uniquely positioned to weigh in on current debates about the future of health care in New Brunswick given his decades-long career as a family physician, president of provincial medical societies, and government minister. In this interview, Furlong outlines his prescription for a sustainable health care system: a proposal to increase accountability among both providers and patients thereby reducing overuse (and misuse) of an overwhelmed and financially strained system to make it affordable and viable in the long term.RésuméDennis Furlong est la personne tout indiquée pour intervenir dans les débats actuels portant sur l’avenir des soins de santé au Nouveau-Brunswick étant donné sa carrière de plusieurs décennies en tant que médecin de famille, président des sociétés médicales provinciales et ministre du gouvernement. Dans la présente entrevue, M. Furlong expose les grandes lignes de ce que serait son ordonnance pour un système de soins de santé durable : accroître la responsabilité des fournisseurs et des patients, ce qui réduirait la surutilisation (et l’utilisation abusive) d’un système saturé et aux ressources financières très limitées afin de le rendre abordable et viable à long terme.Dennis Furlong est la personne tout indiquée pour intervenir dans les débats actuels portant sur l’avenir des soins de santé au Nouveau-Brunswick étant donné sa carrière de plusieurs décennies en tant que médecin de famille, président des sociétés médicales provinciales et ministre du gouvernement. Dans la présente entrevue, M. Furlong expose les grandes lignes de ce que serait son ordonnance pour un système de soins de santé durable : accroître la responsabilité des fournisseurs et des patients, ce qui réduirait la surutilisation (et l’utilisation abusive) d’un système saturé et aux ressources financières très limitées afin de le rendre abordable et viable à long terme

Public Awareness of Aphasia

Aphasia is an acquired communication disorder that affects portions of the brain responsible for language processing and production. It is a disorder that occurs secondary to strokes and other traumatic brain injuries. It is estimated that almost 1 million people in the United States have aphasia. However, there has been very little research regarding public awareness of aphasia, particularly among service-industry workers. The purpose of this study was to analyze the level of public awareness of aphasia in Cleveland, Ohio. This study investigated 100 individuals\u27 knowledge of aphasia by way of a questionnaire, with a focus on respondents who were employed within the public-service sector. Participants were recruited from public areas in Cleveland, Ohio, and filled out a 6-item survey. The responses were then analyzed using quantitative procedures and compared to other existing studies on aphasia awareness. Several categorical variables and their relationship to aphasia awareness were examined to determine if any statistically significant findings existed. Out of the individuals surveyed, 19 had heard of aphasia. The results indicated there was a statistically significant relationship between the age of respondents and aphasia awareness. The education level of respondents also had an impact of aphasia awareness. Occupation, income level, and gender did not appear to have an impact on aphasia awareness. Respondents aged 36-55 years had the highest aphasia awareness rates, and adults ages 56-65 years had the lowest rates of aphasia awareness. Since stroke and aphasia are so closely linked, it is critical to improve public awareness among all age groups, particularly older populations. This can be achieved through education, advocacy and job trainin

Tangible and Financial Satisfaction Among Full-Time Faculty and Adjunct Faculty

The current study examines faculty data from the National Science Foundation’s 2015 National Survey of College Graduates on 4,311 full-time and part-time faculty. Little research exists investigating job satisfaction of adjunct faculty in higher education. Overall job satisfaction was divided into two scales: intangible (i.e., opportunities for advancement, intellectual challenge, degree of independence, job location, level of responsibility, and contribution to society) and financial satisfaction (i.e., job salary, job benefits, and job security). Researchers found significantly different results with full time faculty reporting higher levels of satisfaction when compared to part-time faculty. Limitations and implications for future research are discussed.https://digitalcommons.odu.edu/education_darden/1001/thumbnail.jp

Activation of mammalian Chk1 during DNA replication arrest: a role for Chk1 in the intra-S phase checkpoint monitoring replication origin firing

Checkpoints maintain order and fidelity in the cell cycle by blocking late-occurring events when earlier events are improperly executed. Here we describe evidence for the participation of Chk1 in an intra-S phase checkpoint in mammalian cells. We show that both Chk1 and Chk2 are phosphorylated and activated in a caffeine-sensitive signaling pathway during S phase, but only in response to replication blocks, not during normal S phase progression. Replication block–induced activation of Chk1 and Chk2 occurs normally in ataxia telangiectasia (AT) cells, which are deficient in the S phase response to ionizing radiation (IR). Resumption of synthesis after removal of replication blocks correlates with the inactivation of Chk1 but not Chk2. Using a selective small molecule inhibitor, cells lacking Chk1 function show a progressive change in the global pattern of replication origin firing in the absence of any DNA replication. Thus, Chk1 is apparently necessary for an intra-S phase checkpoint, ensuring that activation of late replication origins is blocked and arrested replication fork integrity is maintained when DNA synthesis is inhibited

The incidence of surgical intervention following a suspected scaphoid fracture

Aims: The underlying natural history of suspected scaphoid fractures (SSF) is unclear and assumed poor. There is an urgent requirement to develop the literature around SSFs to quantify the actual prevalence of intervention following SSF. Defining the risk of intervention following SSF may influence the need for widespread surveillance and screening of SSF injuries and could potentially influence medicolegal actions around missed scaphoid fractures.Methods: Data on SSF was retrospectively gathered from Virtual Fracture Clinic (VFC) across a large Scottish Health Board over a four-year period from 1st January 2018 – 31st December 2021. The Bluespier Electronic Patient Record System identified any surgical procedure being undertaken in relation to a scaphoid injury over the same time period. Isolating patients who underwent surgical intervention for SSF was performed by cross referencing the unique patient Community Health Index [CHI] number for patients who underwent these scaphoid procedures with those seen at VFC for SSF over this four-year period.Results: 1739 patients were identified as having had a SSF. Five patients (0.28%) underwent early ORIF. One patient (0.06%) developed a non-union and underwent ORIF with bone grafting. All 6 patients undergoing surgery were male (p=0.0055). The overall rate of intervention following a SSF was 0.35%. The early intervention rate in those undergoing primary MRI was one (0.36%) compared with 3 in those without (0.27%)(p>0.576, Fishers exact test).Conclusions: Surgical intervention was rare following a SSF and was not required in women. A primary MRI policy did not appear be associated with any change in primary or secondary intervention. This data is the first and largest in recent literature to quantify the prevalence of surgical intervention following a SSF and may be used to guide surveillance and screening pathways as well as defining medicolegal risk involved in missing a true fracture in SSFs

Genome mapping of quantitative trait loci (QTL) controlling domestication traits of intermediate wheatgrass (Thinopyrum intermedium).

Allohexaploid (2n = 6x = 42) intermediate wheatgrass (Thinopyrum intermedium), abbreviated IWG, is an outcrossing perennial grass belonging to the tertiary gene pool of wheat. Perenniality would be valuable option for grain production, but attempts to introgress this complex trait from wheat-Thinopyrum hybrids have not been commercially successful. Efforts to breed IWG itself as a dual-purpose forage and grain crop have demonstrated useful progress and applications, but grain yields are significantly less than wheat. Therefore, genetic and physical maps have been developed to accelerate domestication of IWG. Herein, these maps were used to identify quantitative trait loci (QTLs) and candidate genes associated with IWG grain production traits in a family of 266 full-sib progenies derived from two heterozygous parents, M26 and M35. Transgressive segregation was observed for 17 traits related to seed size, shattering, threshing, inflorescence capacity, fertility, stem size, and flowering time. A total of 111 QTLs were detected in 36 different regions using 3826 genotype-by-sequence markers in 21 linkage groups. The most prominent QTL had a LOD score of 15 with synergistic effects of 29% and 22% over the family means for seed retention and percentage of naked seeds, respectively. Many QTLs aligned with one or more IWG gene models corresponding to 42 possible domestication orthogenes including the wheat Q and RHT genes. A cluster of seed-size and fertility QTLs showed possible alignment to a putative Z self-incompatibility gene, which could have detrimental grain-yield effects when genetic variability is low. These findings elucidate pathways and possible hurdles in the domestication of IWG