Programs of work of Oklahoma N.F.A. chapters

August, 1941.Includes bibliographical references (pages 94-95).To view the abstract, please see the full text of the document

Influence of contouring the lithium metal/solid electrolyte interface on the critical current for dendrites

Contouring or structuring of the lithium/ceramic electrolyte interface and therefore increasing its surface area has been considered as a possible strategy to increase the charging current in solid-state batteries without lithium dendrite formation and short-circuit. By coupling together lithium deposition kinetics and the me chanics of lithium creep within calculations of the current distribution at the interface, and leveraging a model for lithium dendrite growth, we show that efforts to avoid dendrites on charging by increasing the interfacial surface area come with significant limitations associated with the topography of rough surfaces. These limitations are sufficiently severe such that it is very unlikely contouring could increase charging currents while avoiding dendrites and short-circuit to the levels required. For example, we show a sinusoidal surface topography can only raise the charging current before dendrites occur by approx. 50% over a flat interface

Pairwise Measures of Causal Direction in the Epidemiology of Sleep Problems and Depression

Peer reviewe

N-Glycans of Recombinant Human Interferon-Gamma Change During Batch Culture of Chinese - Hamster Ovary Cells

A recombinant Chinese hamster ovary (CHO) cell line making human interferon-gamma (IFN-gamma) was grown in 12-L stirred tank fermenters in three batch fermentations under conditions of constant temperature, pH, and dissolved oxygen tension. In addition to cell growth, metabolite, and productivity data, a detailed analysis of the carbohydrate structures attached to each glycosylation site of IFN-gamma was achieved using matrix-assisted laser desorption mass spectrometry (MALDI-MS) in combination with exoglycosidase array sequencing. Complex biantennary oligosaccharides (particularly Gal(2)GlcNAc(4)Man(3) which was core alpha 1-6 fucosylated at Asn(25) but not at Asn(97)) were most prevalent at both glycosylation sites. However, considerable microheterogeneity arising from the presence of triantennary and truncated glycan structures was also observed. The proportion of the dominant core glycan structure (Gal(2)GlcNAc(4)Man(3) +/- Fuc(1)) decreased by 15-26% during batch culture, with increases in the proportion of oligomannose and truncated glycans over the same time period. Prolonged culture resulting from an extended lag phase led to further accumulation of oligomannose and truncated structures, reaching up to 52% of total glycans attached to Asn(97) by 240 h of culture. The implications of these glycosylation changes for optimizing the time for harvesting cell cultures, and for the clearance of recombinant therapeutic products in vivo are discussed. (C) 1995 John Wiley & Sons, Inc

Dancing amidst the flames: Imagination and self-organization in a minor key

Drawing from Deleuze and Guattari's (1986) formulation of the concept of a 'minor literature' and Nick Thoburn's extension of this into a 'minor politics' (2003a) this paper examines the relation between the workings of the imagination and forms of self-organization found within anticapitalist organizing of the Industrial Workers of the World and related movements. This paper explores the modulations of the social imaginary found within these particular examples as indicative of a more general process of minor composition. Rather than affirming an already existing and known subjective position (of the people, the workers), it will be argued that rather such campaigns have playfully and strategically redirected and appropriated the social energies found within pop culture to articulate their demands. Copyright © 2008 SAGE Publications

Getting the glycosylation right: Implications for the biotechnology industry

Glycosylation is the most extensive of all the posttranslational modifications, and has important functions in the secretion, antigenicity and clearance of glycoproteins. In recent years major advances have been made in the cloning of glycosyltransferase enzymes, in understanding the varied biological functions of carbohydrates, and in the accurate analysis of glycoprotein heterogeneity. In this review we discuss the impact of these advances on the choice of a recombinant host cell line, in optimizing cell culture processes, and in choosing the appropriate level of glycosylation analysis for each stage of product development