A Comparison of Pairs Figure Skaters in Repeated Jumps

Trends in pairs figure skating have shown that increasingly difficult jumps have become an essential aspect of high-level performance, especially in the latter part of a competitive program. We compared a repeated jump power index in a 60 s repeated jump test to determine the relationship of repeated jump test to competitive rank and to measure 2D hip, knee, and ankle angles and angular velocities at 0, 20, 40, and 60 s. Eighteen National Team Pairs Figure Skaters performed a 60 s repeated jump test on a large switch-mat with timing of flight and ground durations and digital video recording. Each 60-s period was divided into 6, 10-s intervals, with power indexes (W/kg) calculated for each 10-s interval. Power index by 10-s interval repeated measures ANOVAs (RMANOVA) showed that males exceeded females at all intervals, and the highest power index interval was during 10 to 20 s for both sexes. RMANOVAs of angles and angular velocities showed main effects for time only. Power index and jumping techniques among figure skaters showed rapid and steady declines over the test duration. Power index can predict approximately 50% of competitive rank variance, and sex differences in jumping technique were rare

GAMBARAN TINGKAT PENGETAHUAN MAHASISWA TENTANG PEMERIKSAAN PAYUDARA SENDIRI DI ATAMBUA

SADARI adalah pemeriksaan payudara sendiri untuk mendeteksi dini adanya kanker payudara. Tujuan dari penelitian ini adalah untuk mengetahui tingkat pengetahuan mahasiswa tentang pemeriksaan payudara sendiri dalam hal Tahu (Know), Memahami (Comprehension), penerapan (aplication) dan analisis (analysis) di Prodi Keperawatan Universitas Timor Kampus Atambua. Penelitian ini menggunakan pendekatan kuantitatif dengan metode deskriptif murni. Sampel yang diteliti yaitu 92 orang dengan menggunakan metode simple random sampling. Hasil penelitian ditemukan 97% responden berpengetahuan “baik”, dan masih ada 3% yang memiliki pengetahuan “cukup”. Hal ini menunjukan bahwa tingkat pengetahuan mahasiswa prodi keperawatan universitas timor kampus atambua sangat tinggi. Setelah mahasiswa mengetahui tentang pemeriksaan payudara sendiri ini, diharapkan mereka akan melakukan pemeriksaan payudara sendiri secara rutin untuk menghindari atau mencegah secara dini terjadi kanker payudara dikemudian hari

A PILOT STUDY TO MEASURE FORCE DEVELOPMENT DURING A SIMULATED MALTESE CROSS FOR GYMNASTICS STILL RINGS

The purpose of this study was to develop a measurement procedure for the Maltese cross performed on still rings. Sixteen elite/international gymnasts participated. Two small force platforms (FPs) interfaced to a portable data logger (100 Hz sampling rate) were placed under the gymnasts’ hands in a simulated Maltese position (i.e., prone). Gymnasts attempted to rise a few centimeters to a Maltese position while vertical ground reaction forces were recorded bilaterally. Results indicated that the FPs had sufficient fidelity to differentiate gymnasts’ abilities to perform a Maltese. This method may serve to gauge the preparedness of male gymnasts performing this important skill

A Pilot Study to Measure Force Development during a Simulated Maltese Cross for Gymnastics Still Rings

The purpose of this study was to develop a measurement procedure for the Maltese cross performed on still rings. Sixteen elite/international gymnasts participated. Two small force platforms (FPs) interfaced to a portable data logger (100 Hz sampling rate) were placed under the gymnasts’ hands in a simulated Maltese position (i.e., prone). Gymnasts attempted to rise a few centimeters to a Maltese position while vertical ground reaction forces were recorded bilaterally. Results indicated that the FPs had sufficient fidelity to differentiate gymnasts’ abilities to perform a Maltese. This method may serve to gauge the preparedness of male gymnasts performing this important skill

Immune-Instructive Polymers Control Macrophage Phenotype and Modulate the Foreign Body Response In Vivo

© 2020 The Author(s) Implantation of medical devices can result in inflammation. A large library of polymers is screened, and a selection found to promote macrophage differentiation towards pro- or anti-inflammatory phenotypes. The bioinstructive properties of these materials are validated within a rodent model. By identifying novel materials with immune-instructive properties, the relationship between material-immune cell interactions could be investigated, and this offers exciting possibilities to design novel bioinstructive materials that can be used for numerous clinical applications including medical implants

Discovery of a polymer resistant to bacterial biofilm, swarming, and encrustation

Innovative approaches to prevent catheter-associated urinary tract infections (CAUTIs) are urgently required. Here, we describe the discovery of an acrylate copolymer capable of resisting single- and multispecies bacterial biofilm formation, swarming, encrustation, and host protein deposition, which are major challenges associated with preventing CAUTIs. After screening ~400 acrylate polymers, poly(tert-butyl cyclohexyl acrylate) was selected for its biofilm- and encrustation-resistant properties. When combined with the swarming inhibitory poly(2-hydroxy-3-phenoxypropyl acrylate), the copolymer retained the bioinstructive properties of the respective homopolymers when challenged with Proteus mirabilis, Pseudomonas aeruginosa, Staphylococcus aureus, and Escherichia coli. Urinary tract catheterization causes the release of host proteins that are exploited by pathogens to colonize catheters. After preconditioning the copolymer with urine collected from patients before and after catheterization, reduced host fibrinogen deposition was observed, and resistance to diverse uropathogens was maintained. These data highlight the potential of the copolymer as a urinary catheter coating for preventing CAUTIs

Translational pharmacology of an inhaled small molecule αvβ6 integrin inhibitor for idiopathic pulmonary fibrosis

The αvβ6 integrin plays a key role in the activation of transforming growth factor-β (TGFβ), a pro-fibrotic mediator that is pivotal to the development of idiopathic pulmonary fibrosis (IPF). We identified a selective small molecule αvβ6 RGD-mimetic, GSK3008348, and profiled it in a range of disease relevant pre-clinical systems. To understand the relationship between target engagement and inhibition of fibrosis, we measured pharmacodynamic and diseaserelated end points. Here we report, GSK3008348 binds to αvβ6 with high affinity in human IPF lung and reduces downstream pro-fibrotic TGFβ signaling to normal levels. In human lung epithelial cells, GSK3008348 induces rapid internalization and lysosomal degradation of the αvβ6 integrin. In the murine bleomycin-induced lung fibrosis model, GSK3008348 engages αvβ6, induces prolonged inhibition of TGFβ signaling and reduces lung collagen deposition and serum C3M, a marker of IPF disease progression. These studies highlight the potential of inhaled GSK3008348 as an anti-fibrotic therapy

Stretching the spines of gymnasts: a review

Gymnastics is noted for involving highly specialized strength, power, agility and flexibility. Flexibility is perhaps the single greatest discriminator of gymnastics from other sports. The extreme ranges of motion achieved by gymnasts require long periods of training, often occupying more than a decade. Gymnasts also start training at an early age (particularly female gymnasts), and the effect of gymnastics training on these young athletes is poorly understood. One of the concerns of many gymnastics professionals is the training of the spine in hyperextension-the ubiquitous 'arch' seen in many gymnastics positions and movements. Training in spine hyperextension usually begins in early childhood through performance of a skill known as a back-bend. Does practising a back-bend and other hyperextension exercises harm young gymnasts? Current information on spine stretching among gymnasts indicates that, within reason, spine stretching does not appear to be an unusual threat to gymnasts' health. However, the paucity of information demands that further study be undertaken