594 research outputs found
X-ray Emission from SN 2012ca: A Type Ia-CSM Supernova Explosion in a Dense Surrounding Medium
X-ray emission is one of the signposts of circumstellar interaction in
supernovae (SNe), but until now, it has been observed only in core-collapse
SNe. The level of thermal X-ray emission is a direct measure of the density of
the circumstellar medium (CSM), and the absence of X-ray emission from Type Ia
SNe has been interpreted as a sign of a very low density CSM. In this paper, we
report late-time (500--800 days after discovery) X-ray detections of SN 2012ca
in {\it Chandra} data. The presence of hydrogen in the initial spectrum led to
a classification of Type Ia-CSM, ostensibly making it the first SN~Ia detected
with X-rays. Our analysis of the X-ray data favors an asymmetric medium, with a
high-density component which supplies the X-ray emission. The data suggest a
number density cm in the higher-density medium, which is
consistent with the large observed Balmer decrement if it arises from
collisional excitation. This is high compared to most core-collapse SNe, but it
may be consistent with densities suggested for some Type IIn or superluminous
SNe. If SN 2012ca is a thermonuclear SN, the large CSM density could imply
clumps in the wind, or a dense torus or disk, consistent with the
single-degenerate channel. A remote possibility for a core-degenerate channel
involves a white dwarf merging with the degenerate core of an asymptotic giant
branch star shortly before the explosion, leading to a common envelope around
the SN.Comment: 11 pages, 4 figures. Accepted to MNRA
High-speed, high-frequency ultrasound, \u3ci\u3ein utero\u3c/i\u3e vector-flow imaging of mouse embryos
Real-time imaging of the embryonic murine cardiovascular system is challenging due to the small size of the mouse embryo and rapid heart rate. High-frequency, linear-array ultrasound systems designed for small-animal imaging provide high-frame-rate and Doppler modes but are limited in regards to the field of view that can be imaged at fine-temporal and -spatial resolution. Here, a plane-wave imaging method was used to obtain high-speed image data from in utero mouse embryos and multi-angle, vector-flow algorithms were applied to the data to provide information on blood flow patterns in major organs. An 18-MHz linear array was used to acquire plane-wave data at absolute frame rates ≥10 kHz using a set of fixed transmission angles. After beamforming, vector-flow processing and image compounding, effective frame rates were on the order of 2 kHz. Data were acquired from the embryonic liver, heart and umbilical cord. Vector-flow results clearly revealed the complex nature of blood-flow patterns in the embryo with fine-temporal and -spatial resolution
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Pulse-Encoded Ultrasound Imagine of the Vitreous With an Annular Array
The vitreous body is nearly transparent both optically and ultrasonically. Conventional 10- to 12-MHz diagnostic ultrasound can detect vitreous inhomogeneities at high gain settings, but has limited resolution and sensitivity, especially outside the fixed focal zone near the retina. To improve visualization of faint intravitreal fluid/gel interfaces, the authors fabricated a spherically curved 20-MHz five-element annular array ultrasound transducer, implemented a synthetic-focusing algorithm to extend the depth-of-field, and used a pulse-encoding strategy to increase sensitivity. The authors evaluated a human subject with a recent posterior vitreous detachment and compared the annular array with conventional 10-MHz ultrasound and spectral-domain optical coherence tomography. With synthetic focusing and chirp pulse-encoding, the array allowed visualization of the formed and fluid components of the vitreous with improved sensitivity and resolution compared with the conventional B-scan. Although optical coherence tomography allowed assessment of the posterior vitreoretinal interface, the ultrasound array allowed evaluation of the entire vitreous body
Epidemiology, genetics, and subtyping of preserved ratio impaired spirometry (PRISm) in COPDGene.
BackgroundPreserved Ratio Impaired Spirometry (PRISm), defined as a reduced FEV1 in the setting of a preserved FEV1/FVC ratio, is highly prevalent and is associated with increased respiratory symptoms, systemic inflammation, and mortality. Studies investigating quantitative chest tomographic features, genetic associations, and subtypes in PRISm subjects have not been reported.MethodsData from current and former smokers enrolled in COPDGene (n = 10,192), an observational, cross-sectional study which recruited subjects aged 45-80 with ≥10 pack years of smoking, were analyzed. To identify epidemiological and radiographic predictors of PRISm, we performed univariate and multivariate analyses comparing PRISm subjects both to control subjects with normal spirometry and to subjects with COPD. To investigate common genetic predictors of PRISm, we performed a genome-wide association study (GWAS). To explore potential subgroups within PRISm, we performed unsupervised k-means clustering.ResultsThe prevalence of PRISm in COPDGene is 12.3%. Increased dyspnea, reduced 6-minute walk distance, increased percent emphysema and decreased total lung capacity, as well as increased segmental bronchial wall area percentage were significant predictors (p-value <0.05) of PRISm status when compared to control subjects in multivariate models. Although no common genetic variants were identified on GWAS testing, a significant association with Klinefelter's syndrome (47XXY) was observed (p-value < 0.001). Subgroups identified through k-means clustering include a putative "COPD-subtype", "Restrictive-subtype", and a highly symptomatic "Metabolic-subtype".ConclusionsPRISm subjects are clinically and genetically heterogeneous. Future investigations into the pathophysiological mechanisms behind and potential treatment options for subgroups within PRISm are warranted.Trial registrationClinicaltrials.gov Identifier: NCT000608764
High-Velocity Line Forming Regions in the Type Ia Supernova 2009ig
We report measurements and analysis of high-velocity (> 20,000 km/s) and
photospheric absorption features in a series of spectra of the Type Ia
supernova (SN) 2009ig obtained between -14d and +13d with respect to the time
of maximum B-band luminosity. We identify lines of Si II, Si III, S II, Ca II
and Fe II that produce both high-velocity (HVF) and photospheric-velocity (PVF)
absorption features. SN 2009ig is unusual for the large number of lines with
detectable HVF in the spectra, but the light-curve parameters correspond to a
slightly overluminous but unexceptional SN Ia (M_B = -19.46 mag and Delta_m15
(B) = 0.90 mag). Similarly, the Si II lambda_6355 velocity at the time of B-max
is greater than "normal" for a SN Ia, but it is not extreme (v_Si = 13,400
km/s). The -14d and -13d spectra clearly resolve HVF from Si II lambda_6355 as
separate absorptions from a detached line forming region. At these very early
phases, detached HVF are prevalent in all lines. From -12d to -6d, HVF and PVF
are detected simultaneously, and the two line forming regions maintain a
constant separation of about 8,000 km/s. After -6d all absorption features are
PVF. The observations of SN 2009ig provide a complete picture of the transition
from HVF to PVF. Most SN Ia show evidence for HVF from multiple lines in
spectra obtained before -10d, and we compare the spectra of SN 2009ig to
observations of other SN. We show that each of the unusual line profiles for Si
II lambda_6355 found in early-time spectra of SN Ia correlate to a specific
phase in a common development sequence from HVF to PVF.Comment: 19 pages, 11figures, 4 tables, submitted to Ap
A High-Resolution Spectroscopic Search for the Remaining Donor for Tycho's Supernova
In this paper, we report on our analysis using Hubble Space Telescope
astrometry and Keck-I HIRES spectroscopy of the central six stars of Tycho's
supernova remnant (SN 1572). With these data, we measured the proper motions,
radial velocities, rotational velocities, and chemical abundances of these
objects. Regarding the chemical abundances, we do not confirm the unusu- ally
high [Ni/Fe] ratio previously reported for Tycho-G. Rather, we find that for
all metrics in all stars, none exhibit the characteristics expected from
traditional SN Ia single-degenerate-scenario calculations. The only possible
exception is Tycho-B, a rare, metal-poor A-type star; however, we are unable to
find a suitable scenario for it. Thus, we suggest that SN 1572 cannot be
explained by the standard single-degenerate model.Comment: 34 pages, 11 Figures, revised and resubmitted to Ap
Swift J2058.4+0516: Discovery of a Possible Second Relativistic Tidal Disruption Flare?
We report the discovery by the Swift hard X-ray monitor of the transient
source Swift J2058.4+0516 (Sw J2058+05). Our multi-wavelength follow-up
campaign uncovered a long-lived (duration >~ months), luminous X-ray (L_X,iso ~
3 x 10^47 erg s^-1) and radio (nu L_nu,iso ~ 10^42 erg s^-1) counterpart. The
associated optical emission, however, from which we measure a redshift of
1.1853, is relatively faint, and this is not due to a large amount of dust
extinction in the host galaxy. Based on numerous similarities with the recently
discovered GRB 110328A / Swift J164449.3+573451 (Sw J1644+57), we suggest that
Sw J2058+05 may be the second member of a new class of relativistic outbursts
resulting from the tidal disruption of a star by a supermassive black hole. If
so, the relative rarity of these sources (compared with the expected rate of
tidal disruptions) implies that either these outflows are extremely narrowly
collimated (theta < 1 degree), or only a small fraction of tidal disruptions
generate relativistic ejecta. Analogous to the case of long-duration gamma-ray
bursts and core-collapse supernovae, we speculate that rapid spin of the black
hole may be a necessary condition to generate the relativistic component.
Alternatively, if powered by gas accretion (i.e., an active galactic nucleus
[AGN]), Sw J2058+05 would seem to represent a new mode of variability in these
sources, as the observed properties appear largely inconsistent with known
classes of AGNs capable of generating relativistic jets (blazars, narrow-line
Seyfert 1 galaxies).Comment: Minor typos correcte
The Massive Progenitor of the Type II-Linear Supernova 2009kr
We present early-time photometric and spectroscopic observations of supernova (SN) 2009kr in NGC 1832. We find that its properties to date support its classification as Type II-linear (SN II-L), a relatively rare subclass of core-collapse supernovae (SNe). We have also identified a candidate for the SN progenitor star through comparison of pre-explosion, archival images taken with WFPC2 on board the Hubble Space Telescope with SN images obtained using adaptive optics plus NIRC2 on the 10 m Keck-II telescope. Although the host galaxy's substantial distance (similar to 26 Mpc) results in large uncertainties in the relative astrometry, we find that if this candidate is indeed the progenitor, it is a highly luminous (M(V)(0) = -7.8 mag) yellow supergiant with initial mass similar to 18-24 M(circle dot). This would be the first time that an SN II-L progenitor has been directly identified. Its mass may be a bridge between the upper initial mass limit for the more common Type II-plateau SNe and the inferred initial mass estimate for one Type II-narrow SN.Hungarian OTKA K76816NSF AST-0707769, AST-0908886Sylvia & Jim Katzman FoundationTABASGO FoundationNASA through STScI AR-11248, GO-10877Harvard UniversityUC BerkeleyUniversity of VirginiaNASA/Swift NNX09AQ66GDOEAstronom
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Non-Planar Pad-Printed Think-Film Focused High-Frequency Ultrasonic Transducers for Imaging and Therapeutic Applications
Pad-printed thick-film transducers have been shown to be an interesting alternative to lapped bulk piezoceramics, because the film is deposited with the required thickness, size, and geometry, thus avoiding any subsequent machining to achieve geometrical focusing. Their electromechanical properties are close to those of bulk ceramics with similar composition despite having a higher porosity. In this paper, padprinted high-frequency transducers based on a low-loss piezoceramic composition are designed and fabricated. High-porosity ceramic cylinders with a spherical top surface are used as the backing substrate. The transducers are characterized in view of imaging applications and their imaging capabilities are evaluated with phantoms containing spherical inclusions and in different biological tissues. In addition, the transducers are evaluated for their capability to produce high-acoustic intensities at frequencies around 20 MHz. High-intensity measurements, obtained with a calibrated hydrophone, show that transducer performance is promising for applications that would require the same device to be used for imaging and for therapy. Nevertheless, the transducer design can be improved, and simulation studies are performed to find a better compromise between low-power and high-power performance. The size, geometry, and constitutive materials of optimized configurations are proposed and their feasibility is discussed
Genome analysis with inter-nucleotide distances
Motivation: DNA sequences can be represented by sequences of four symbols, but it is often useful to convert the symbols into real or complex numbers for further analysis. Several mapping schemes have been used in the past, but they seem unrelated to any intrinsic characteristic of DNA. The objective of this work was to find a mapping scheme directly related to DNA characteristics and that would be useful in discriminating between different species. Mathematical models to explore DNA correlation structures may contribute to a better knowledge of the DNA and to find a concise DNA description
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