16 research outputs found
Exploration of Shared Genetic Architecture Between Subcortical Brain Volumes and Anorexia Nervosa
- Author
- Abramovic Lucija
- Adams Hieab HH
- Adan Roger
- Agartz Ingrid
- Alfredsson Lars
- Alhusaini Saud
- Almasy Laura
- Ames David
- Andersson Micael
- Ando Tetsuya
- Andreassen Ole
- Andreassen Ole A
- Anttila Verneri
- Arepalli Sampath
- Arias-Vasquez Alejandro
- Aribisala Benjamin S
- Armstrong Nicola J
- Aschauer Harald
- Ashbrook David G
- Assareh Amelia A
- Athanasiu Lavinia
- Baker Jessica
- Barrett Jeffrey
- Bastin Mark E
- Batury V-L
- Becker James T
- Bencko Vladimir
- Bergen Andrew
- Bernard Manon
- Berrettini Wade
- Birgegard Andreas
- Bis Joshua C
- Blangero John
- Bohlken Marc M
- Boks Marco P
- Boni Claudette
- Boomsma Dorret I
- Bralten Janita
- Brandt Harry
- Breen Gerome
- Brodaty Henry
- Brouwer Rachel M
- Brown Andrew A
- Brunner Han G
- Buckner Randy L
- Buitelaar Jan K
- Bulayeva Kazima B
- Bulik CM
- Bulik Cynthia M
- Bulik-Sullivan Brendan
- Burghardt Roland
- Cahn Wiepke
- Calhoun Vince D
- Cannon Dara M
- Carlberg Laura
- Carless Melanie A
- Cassina Matteo
- Cavalleri Gianpiero L
- Chakravarty M Mallar
- Chauhan Ganesh
- Chen Qiang
- Cheung J
- Ching Christopher RK
- Cichon Carolyn Cesta Sven
- Cichon Sven
- Clementi Maurizio
- Cohen-Woods Sarah
- Coleman Joni
- Cone Roger
- Cookson Mark R
- Corvin Aiden
- Courtet Philippe
- Crawford Steven
- Crespo-Facorro Benedicto
- Crow Scott
- Crowley Jim
- Cuellar-Partida Gabriel
- Curran Joanne E
- Czisch Michael
- Dale Anders M
- Danner Unna
- Davies Gareth E
- Davis Oliver
- de Geus Eco JC
- de Zubicaray Greig I
- de Zwaan Martina
- Deary Ian J
- Dedoussis George
- Degortes Daniela
- Delanty Norman
- Den Braber Anouk
- Depondt Chantal
- DeSocio Janiece
- Desrivieres Sylvane
- Dick Danielle
- Dikeos Dimitris
- Dillman Allissa
- Dina Christian
- Ding Bo
- Djurovic Srdjan
- Dmitrzak-Weglarz Monika
- Docampo Elisa
- Donohoe Gary
- Drevets Wayne C
- Duggirala Ravi
- Duncan Laramie
- Dyer Thomas D
- Ebling Maritza
- Egberts Karin
- Ehrlich Stefan
- Ehrlich Stefan
- Ehrlich Stefan
- Erk Susanne
- Escaramis Georgia
- Esko Tonu
- Espeseth Thomas
- Espeseth Thomas
- Estivill Xavier
- Favaro Angela
- Fedko Iryna O
- Fernandez Guillen
- Fernandez-Aranda Fernando
- Ferrucci Luigi
- Fichter Manfred
- Finan Chris
- Fischer Krista
- Fischl Bruce
- Fisher Simon E
- Floyd James
- Focker Manuel
- Foretova Lenka
- Foroud Tatiana M
- Forzan Monica
- Fox Caroline
- Fox Peter T
- Francks Clyde
- Franke Barbara
- Franklin Christopher
- Fukunaga Masaki
- Gallinger Valerie Gaborieau Steven
- Gambaro Giovanni
- Gaspar Helena
- Gibbs J Raphael
- Giddaluru Sudheer
- Giegling Ina
- Glahn David C
- Goldman Aaron L
- Goldstein Jackie
- Gollub Randy L
- Gonidakis Fragiskos
- Goring Harald HH
- Gorwood Philip
- Grabe Hans J
- Gratacos Monica
- Green Robert C
- Greve Douglas
- Grimm Oliver
- Grp ENIGMA Genetics Working
- Gruber Oliver
- Guadalupe Tulio
- Gudnason Vilmundur
- Guelfi Sebastian
- Guillaume Sebastien
- Guo Yiran
- Hager Reinmar
- Hakobjan Marina MH
- Hakonarson Hakon
- Halmi Katherine
- Hansell Narelle K
- Hardy John
- Harrison Rebecca
- Hartberg Cecilie B
- Hartman Catharina A
- Hashimoto Ryota
- Hass Johanna
- Hatzikotoulas Konstantinos
- Haukvik Unn K
- Hauser Joanna
- Hebebrand Johannes
- Hegenscheid Katrin
- Heinz Andreas
- Heister Angelien JGAM
- Helder Sietske
- Hendriks Judith
- Herms Stefan
- Hernandez Dena G
- Hernandez Maria C Valdes
- Herpertz-Dahlmann Beate
- Herzog Wolfgang
- Heslenfeld Dirk J
- Hibar D
- Hibar Derrek P
- Hilliard Christopher
- Hinney Anke
- Ho Beng-Choon
- Hoekstra Pieter J
- Hoffmann Wolfgang
- Hohn David
- Holmes Avram J
- Holsboer Florian
- Homuth Georg
- Hoogman Martine
- Hosten Norbert
- Hottenga Jouke-Jan
- Huckins Laura
- Hudson James
- Huemer Julia
- Ikeda Masashi
- Ikram M Arfan
- Imgart Hartmut
- Inoko Hidetoshi
- Jahanshad N
- Jahanshad Neda
- Jamain Sigrid Jall Stephane
- Janout Vladimir
- Janowitz Deborah
- Jenkinson Mark
- Jia Tianye
- Jimenez-Murcia Susana
- Johnson Craig
- Johnson Robert
- Jonsson Erik G
- Jordan Jenny
- Jr Jack Clifford R
- Jr Kent Jack W
- Julia Antonio
- Jureus Anders
- Kahn Rene S
- Kalsi Gursharan
- Kaminska Debora
- Kanai Ryota
- Kaplan Allan
- Kaprio Jaakko
- Karhunen Leila
- Karwautz Andreas
- Kas Martien
- Kasperaviciute Dalia
- Kaye Walter
- Keil Maria
- Kennedy James
- Kennedy Martin
- Keski-Rahkonen Anna
- Kiezebrink Kirsty
- Kim Sungeun
- Kim Youl-Ri
- Klareskog Lars
- Klein Marieke
- Kloszewska Iwona
- Klump Kelly
- Knudsen Gun Peggy
- Kochunov Peter
- Koeleman Bobby
- Koubek Doris
- Kraemer Bernd
- Kwok John B
- La Via Maria
- Landen Mikael
- Launer Lenore J
- Lawrie Stephen M
- Le Hellard Stephanie
- Le Hellard Stephanie
- Leboyer Marion
- Lee Phil H
- Levitan Robert
- Li Dong
- Lichtenstein Paul
- Liewald David CM
- Lilenfeld Lisa
- Lissowska Jolanta
- Liu Xinmin
- Longo Dan L
- Longstreth WT
- Loohuis Loes M Olde
- Lopez Lorna M
- Lovestone Simon
- Lu Lu
- Luciano Michelle
- Lundervold Astri
- Luting Xue
- Macare Christine
- Magistretti Pierre
- Maj Mario
- Makkinje Remco RR
- Mannik Katrin
- Marsal Sara
- Martin Nicholas
- Martin Nicholas G
- Matarin Mar
- Mather Karen A
- Mattay Venkata S
- Mattheisen Manuel
- Mattingsdal Morten
- Mazoyer Bernard
- McDevitt Sara
- McDonald Colm
- McGuffin Peter
- McIntosh Andrew M
- Mckay David R
- McMahon Francis J
- McMahon Katie L
- Mecocci Patrizia
- Medland Sarah E
- Meisenzahl Eva
- Melle Ingrid
- Merl Elisabeth
- Metspalu Andres
- Meulenbelt Ingrid
- Meyer-Lindenberg Andreas
- Micali Nadia
- Milaneschi Yuri
- Mitchell James
- Mitchell Karen
- Mohnke Sebastian
- Monteleone Alessio Maria
- Monteleone Palmiero
- Montgomery Grant
- Montgomery Grant W
- Morris Derek W
- Mortensen Preben
- Mostert Jeanette C
- Mueller Timo
- Mueller-Myhsok Bertram
- Muhleisen Thomas W
- Munn-Chernoff Melissa
- Naber Marlies AM
- Nacmias Benedetta
- Nalls Michael A
- Nauck Matthias
- Navratilova Marie
- Needham Margaret
- Nho Kwangsik
- Nichols Thomas E
- Nilsson Ida
- Nilsson Lars G
- Norring Claes
- Nothen Markus M
- Ntalla Ioanna
- Nugent Allison C
- Nyberg Lars
- Nyquist Paul
- O'Toole Julie
- Ohi Kazutaka
- Olvera Rene L
- Ophoff Roel
- Ophoff Roel A
- Palotie Aarno
- Pandolfo Massimo
- Pantel Jacques
- Papezova Hana
- Papmeyer Martina
- Paus Tomas
- Pausova Zdenka
- Penninx Brenda WJH
- Perez-Iglesias Rocio
- Perica Vesna Boraska
- PGC-ED
- Pike G Bruce
- Pinto Richard Parker Dalila
- Pol Hilleke E Hulshoff
- Potkin Steven G
- Putz Benno
- Rabionet Raquel
- Raevuori Anu
- Rajewski Andrzej
- Ramasamy Adaikalavan
- Ramoz Nicolas
- Rayner N William
- Reichborn-Kjennerud Ted
- Reinvang Ivar
- Renteria Miguel E
- Reppermund Simone
- Ricca Valdo
- Rietschel Marcella
- Ripatti Samuli
- Ripke Stephan
- Risacher Shannon L
- Ritschel Franziska
- Roberts Marion
- Roffman Joshua L
- Roiz-Santianez Roberto
- Romanczuk-Seiferth Nina
- Rose Emma J
- Rosen Glenn D
- Rotondo Alessandro
- Rujescu Dan
- Rujescu Dan
- Rybakowski Filip
- Ryten Mina
- Sachdev Perminder S
- Salami Alireza
- Samann Philipp G
- Santonastaso Paolo
- Satizabal Claudia L
- Saykin Andrew J
- Scherag Andre
- Scherer Stephen
- Schmaal Lianne
- Schmidt Helena
- Schmidt Reinhold
- Schmidt Ulrike
- Schnell Knut
- Schofield Peter R
- Schork Andrew J
- Schork Nicholas
- Schosser Alexandra
- Schumann Gunter
- Scott Laura
- Seiler Stephan
- Seitz J
- Seitz Jochen
- Seshadri Sudha
- Shen Li
- Shin Jean
- Simmons Andrew
- Singleton Andrew
- Sisodiya Sanjay M
- Slachtova Lenka
- Sladek Robert
- Slagboom P Eline
- Slof-Op't Landt Margarita
- Slopien Agnieszka
- Smith Colin
- Smith Tosha
- Smoller Jordan W
- Soininen Hilkka
- Soranzo Nicole
- Sorbi Sandro
- Southam Lorraine
- Sprooten Emma
- Steen Vidar
- Steen Vidar M
- Stein Jason L
- Strengman Eric
- Strike Lachlan T
- Strober Michael
- Sussmann Jessika E
- Szatkiewicz Jin
- Szeszenia-Dabrowska Neonila
- Tachmazidou Ioanna
- Tenconi Elena
- Teumer Alexander
- Thalamuthu Anbupalam
- Thompson Paul M
- Thompson PM
- Thornton Laura
- Toga Arthur W
- Toro Roberto
- Tortorella Alfonso
- Tozzi Federica
- Trabzuni Daniah
- Traynor Bryan J
- Treasure Janet
- Troncoso Juan
- Tschop Matthias
- Tsitsika Artemis
- Turner Jessica A
- Tziouvas Konstantinos
- van Bokhoven Hans
- van der Brug Marcel
- van der Lee Sven J
- van der Marel Saskia SL
- van der Wee Nic JA
- van Donkelaar Marjolein MJ
- van Duijn Cornelia M
- van Eijk Kristel R
- van Elburg Annemarie
- van Furth Eric
- van Haren Neeltje EM
- van Hulzen Kimm JE
- van Tol Marie-Jose
- van't Ent Dennis
- Veltman Dick J
- Vinke Louis N
- Volzke Henry
- Wade Tracey
- Wagner Gudrun
- Walter Henrik
- Walters Raymond
- Walters Raymond K
- Walton E
- Walton Esther
- Walton Esther
- Wardlaw Joanna M
- Wassink Thomas H
- Watson Hunna
- Weale Michael E
- Weinberger Daniel R
- Weiner Michael W
- Wen Wei
- Westlye Lars T
- Westman Eric
- Whelan Christopher D
- White Tonya
- Wichmann H-Erich
- Widen Elisabeth
- Williams Robert W
- Winkler Anderson M
- Wittfeld Katharina
- Woldehawariat Girma
- Wolf Christiane
- Woodside D Blake
- Wright Margaret J
- Yanek Lisa R
- Yanovski Jack
- Yao Shuyang
- Yilmaz Z
- Yilmaz Zeynep
- Zerwas Stephanie
- Zielke Ronald H
- Zipfel Stephan
- Zonderman Alan B
- Zwiers Marcel P
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/07/2019
- Field of study
Longitudinal Outcomes in the 2014 Acute Flaccid Paralysis Cluster in Canada
- Author
- Aleksandra Mineyko
- Ari Bitnun
- Ayscue P
- Carmen Yea
- Centres for Disease Control and Prevention
- Chen CY
- Christoph Licht
- Daniela Pohl
- E. Ann Yeh
- Geneviève Bernard
- Jason Brophy
- Jean K. Mah
- Jeffrey M. Pernica
- Jiri Vajsar
- Joan Robinson
- Juliette Hukin
- Katherine Muir
- Kathryn Selby
- Kevin Jones
- Lang M
- Megan Crone
- Michelle Barton
- Mubeen F. Rafay
- Persu A
- Robert Pless
- Rotondo J
- Shalini Desai
- Sherwood MD
- Skowronski DM
- Sunita Venkateswaran
- Susan Richardson
- Publication venue
- 'SAGE Publications'
- Publication date
- Field of study
Military medical revolution
- Author
- Allcock
- Andrew P. Cap
- Avaro
- Beekley
- Beninati
- Blackbourne
- Brian J. Eastridge
- Brohi
- Buckenmaier
- Burkhardt
- Burkhardt
- Cannon
- Christopher V. Maani
- Chung
- Chung
- Chung
- Chung
- Chung
- Clouse
- Coldren
- David G. Baer
- De Waele
- Demetriades
- Doran
- DuBose
- Evan M. Renz
- Fang
- Geiger
- Gifford
- Gifford
- Hancock
- Heimbach
- Hess
- Higgins
- Hildebrand
- Himmelseher
- Hinck
- Holcomb
- Huckfeldt
- Hudson
- Jaffee
- Jeffrey Bailey
- Johannigman
- John B. Holcomb
- Jonathan Morrison
- Joseph C. Wenke
- Joseph DuBose
- Kauvar
- Kevin K. Chung
- Kimberlie A. Biever
- Lehmann
- Leininger
- Leppaniemi
- Li
- Lorne H. Blackbourne
- Mabry
- Manofo
- Mark J. Midwinter
- Martini
- Mason
- Morrison
- Nessen
- Niles
- Owens
- Peck
- Petkar
- Possley
- Powell
- Propper
- Quan
- Ramón F. Cestero
- Rasmussen
- Rasmussen
- Raymond Fang
- Rich
- Robert L. Mabry
- Rosenfeld
- Rotondo
- Salinas
- Scalea
- Schirmer
- Stannard
- Stannard
- Stiver
- Stojadinovic
- Taller
- Todd E. Rasmussen
- Vikhyat Bebarta
- White
- White
- Woodward
- Publication venue
- 'Ovid Technologies (Wolters Kluwer Health)'
- Publication date
- Field of study
Compensatory dendritic cell development mediated by BATF–IRF interactions
- Author
- A Brüstle
- AL Brass
- Ansuman T. Satpathy
- AT Satpathy
- BC Betz
- Brian T. Edelson
- BT Edelson
- BT Edelson
- BT Edelson
- BT Edelson
- BT Edelson
- BU Schraml
- BU Schraml
- C Li
- CF Eisenbeis
- CF Eisenbeis
- Christina L. Stallings
- Cora T. Aurthur
- D Bending
- DR Echlin
- E Kanbe
- EF Wagner
- Elke Glasmacher
- F Ginhoux
- H Matsushita
- Harinder Singh
- J Aliberti
- JD Dignam
- Jeffrey A. Rotondo
- JF Marquis
- JM den Haan
- JP Saeij
- JR Gorman
- JR Sedy
- JT Jackson
- Jörn C. Albring
- K Hildner
- K Hildner
- Kenneth M. Murphy
- KL Williams
- L Bar-On
- L Chen
- L. David Sibley
- Leslie A. Weiss
- M Mashayekhi
- M Mashayekhi
- Michael Behnke
- MJ Dorsey
- Mona Mashayekhi
- MS Behnke
- Nicole M. Kretzer
- NS Wilson
- P Tailor
- Peng Li
- R Sciammas
- RL Modlin
- Robert D. Schreiber
- Roxane Tussiwand
- S Iiizumi
- S Ranganath
- S Ranganath
- Samuel S. K. Lam
- SJ Szabo
- T Ravasi
- T Tamura
- Theresa L. Murphy
- TS Heng
- U Klein
- W Ise
- W Ise
- Wan-Ling Lee
- Warren J. Leonard
- Wei Liao
- Wumesh KC
- Xiaodi Wu
- ZZ Su
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index
- Author
- Abecasis G. R.
- Absher D.
- Adair L. S.
- Adan R.
- Adan Roger A. H.
- Alavere H.
- Albrecht E.
- Albrecht E.
- Alexander Graeme
- Alfredsson Lars
- Alizadeh B.
- Amin N.
- Amin N.
- Amouyel P.
- Anderson Carl A.
- Ando Tetsuya
- Andreassen Ole A.
- Ang W.
- Antel J.
- Aschauer Harald
- Aspelund T.
- Asselbergs F. W.
- Assimes T. L.
- Atalay M.
- Atalay M.
- Attwood A. P.
- Baker Jessica H.
- Balmforth A. J.
- Bandinelli S.
- Barrett Jeff C.
- Barrett Jeffrey C.
- Barroso I.
- Barroso I.
- Basart H.
- Beilby J.
- Bencko Vladimir
- Benke K.
- Berenson G. S.
- Berg J.
- Bergen A. W.
- Bergen Andrew W.
- Bergen N.
- Bergmann S.
- Berndt S. I.
- Berrettini W.
- Berrettini Wade
- Berrettini Wade H.
- Berry D. J.
- Bierut L. J.
- Blackburn H.
- Blackburn Hannah
- Blackwood D.
- Boehm B. O.
- Boehnke M.
- Boerwinkle E.
- Boerwinkle E.
- Boezen H. M.
- Boni Claudette
- Bonnycastle L. L.
- Boomsma D. I.
- Boomsma D. I.
- Boraska Perica V.
- Borecki I. B.
- Boyd H. A.
- Bradfield J. P.
- Bragg-Gresham J. L.
- Brambilla P.
- Brandt Harry
- Brandys M.
- Brandys Marek K.
- Breen Gerome
- Bruinenberg M.
- Bruinenberg M.
- Bruson Alice
- Bulik C. M.
- Bulik Cynthia M.
- Bulik Cynthia M.
- Bulik Cynthia M.
- Burghardt Roland
- Buring J. E.
- Busonero F.
- Byrne E. M.
- Bühren Katharina
- Bültmann U.
- Cadby G.
- Campbell H.
- Campbell H.
- Campbell H.
- Carlberg Laura
- Caulfield M. J.
- Cavanagh J.
- Chanock S. J.
- Chanock S. J.
- Charoen P.
- Chasman D. I.
- Chasman D. I.
- Chen W.
- Chen Wei-Min
- Children's Hospital of Philadelphia/Price Foundation
- Chines P. S.
- Cichon Sven
- Clair D. S.
- Clementi Maurizio
- Cohen-Woods Sarah
- Coin L.
- Collier D.
- Collier David A.
- Collier David A.
- Collins F. S.
- Cone Roger D.
- Conlon Peter J.
- Connell J.
- Connell J. M.
- Connor M.
- Cookson W.
- Cooper C.
- Cornelis M. C.
- Corre T.
- Couper D.
- Cousminer D. L.
- Cousminer D. L.
- Coviello A. D.
- Crawford Steve
- Crisponi L.
- Croteau-Chonka D. C.
- Crow Scott
- Cunningham-Burley S.
- Cupples L.
- Cusi D.
- d'Adamo P.
- Dackor Jennifer
- Danner Unna N.
- Das S.
- Davey Smith G.
- Davis O. S.
- Davis Oliver S. P.
- Day F. R.
- de Bakker P.
- de Boer R.
- de Faire U.
- de Faire U.
- de Geus E. J.
- de Kove Carolien
- de Vegt F.
- de Zwaan M.
- de Zwaan Martina
- Deary I.
- Dedoussis G. V.
- Dedoussis G. V.
- Dedoussis George
- Degortes Daniela
- Dei M.
- Deloukas P.
- Deloukas P.
- Demerath E. W.
- den Heijer M.
- DeSocio Janiece E.
- Di Blasio A. M.
- Dick Danielle M.
- Dikeos Dimitris
- Dimitriou M.
- Dina Christian
- Ding Bo
- Dmitrzak-Weglarz Monika
- Docampo Elisa
- Dominiczak A.
- Dominiczak Anna
- Duncanson Audrey
- Döring A.
- Easton D. F.
- Econs M. J.
- Edkins S.
- Edkins Sarah
- Egberts K. M.
- Egberts Karin
- EGG
- Ehrlich S.
- Ehrlich Stefan
- Eiriksdottir G.
- Eklund N.
- Elks C. E.
- Elliott P.
- Ellis P.
- Emilsson V.
- Erdmann J.
- Eriksson J.
- Eriksson J. G.
- Escaramí Geòrgia
- Esko T.
- Esko T.
- Esko Tõnu
- Espeseth Thomas
- Estivill X.
- Estivill Xavier
- Estrada K.
- Evans D. M.
- Evans D. M.
- Fall T.
- Farmer Anne
- Farrall M.
- Favaro Angela
- Feenstra B.
- Feenstra B.
- Feitosa M. F.
- Fernández-Aranda Fernando
- Ferrario M. M.
- Ferreira T.
- Ferreli L.
- Ferrières J.
- Ferrucci L.
- Fichter Manfred M.
- Finan Chris
- Fischer K.
- Fischer Krista
- FitzPatrick B.
- Flexeder C.
- Floyd James A. B.
- Floyd James A. B.
- Folsom A. R.
- Ford I.
- Foretova Lenka
- Foroud T.
- Forzan Monica
- Fox C. S.
- Franceschini N.
- Franke L.
- Franke L.
- Franklin C. S.
- Franklin Christopher S.
- Franklin Christopher S.
- Franks P. W.
- Frau F.
- Frayling T.
- Frayling T.
- Freathy R. M.
- Froguel P.
- Föcker M.
- Gaborieau Valerie
- Gaillard R.
- Gallinger Steven
- Gambaro Giovanni
- Ganna A.
- Garcia M.
- Gasparini P.
- GCAN
- Gejman P. V.
- Geleijnse M.
- Geller F.
- Geller F.
- Gentilini D.
- Gertz R.
- GIANT
- Gieger C.
- Gieger C.
- Giegling Ina
- Gillman M.
- Gillman Mathew
- Goel A.
- Goh L. K.
- Gonidakis Fragiskos
- Gorwood Philip
- Grallert H.
- Grant S. F.
- Grant S. F. A.
- Gratacos Monica
- Grau A.
- Gray Emma
- Groen-Blokhuis M.
- Groop L. C.
- Grönberg H.
- Gudbjartsson D. F.
- Gudnason V.
- Gudnason V.
- Guo Y.
- Guo Yiran
- Gustafsson S.
- Guxens M.
- Gyllensten U.
- Haddow G.
- Hadley D.
- Hakonarson H.
- Hakonarson H.
- Hakonarson Hakon
- Hall A. S.
- Hall P.
- Hall P.
- Halmi Katherine A.
- Hamsten A.
- Hankinson S. E.
- Haritunian T.
- Harris T. B.
- Harris T. B.
- Harst P. V.
- Hartikainen A. L.
- Hattersley A. T.
- Hauser Joanna
- Haworth C. M.
- Hayward C.
- Hayward C.
- He C.
- Heard-Costa N. L.
- Heath A. C.
- Heath A. C.
- Hebebrand J.
- Hebebrand J.
- Hebebrand J.
- Hebebrand Johannes
- Heid I. M.
- Heid I. M.
- Heinrich J.
- Helder Sietske
- Hellard Stephanie Le
- Hendriks Judith
- Hengstenberg C.
- Herms Stefan
- Hernandez D. G.
- Herpertz-Dahlmann B.
- Herpertz-Dahlmann Beate
- Herzog W.
- Herzog Wolfgang
- Hicks A. A.
- Hill Adrian
- Hillege H.
- Hilliard Christopher E.
- Hingorani A.
- Hinney A.
- Hinney A.
- Hinney A.
- Hinney Anke
- Hirschhorn J. N.
- Hirschhorn J. N.
- Hocher B.
- Hofman A.
- Hofman A.
- Holloway J. W.
- Holst C.
- Homuth G.
- Horikoshi M.
- Hottenga J. J.
- Hottenga J. J.
- Hottenga J. J.
- Hovingh K. G.
- Hu F. B.
- Hu F. B.
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- Widén Elisabeth
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- Woodside D. Blake
- Workalemahu T.
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- WTCCC3
- Yaghootkar H.
- Yang J.
- Yilmaz Zeynep
- Young L.
- Zeggini E.
- Zeggini E.
- Zeggini Eleftheria
- Zeggini Eleftheria
- Zerwas Stephanie
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- Zhao J. H.
- Zhuang W. V.
- Zillikens M.
- Zipfel S.
- Zipfel Stephan
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 17/05/2016
- Field of study
The maintenance of normal body weight is disrupted in patients with anorexia nervosa (AN) for prolonged periods of time. Prior to the onset of AN, premorbid body mass index (BMI) spans the entire range from underweight to obese. After recovery, patients have reduced rates of overweight and obesity. As such, loci involved in body weight regulation may also be relevant for AN and vice versa. Our primary analysis comprised a cross-trait analysis of the 1000 single-nucleotide polymorphisms (SNPs) with the lowest P-values in a genome-wide association meta-analysis (GWAMA) of AN (GCAN) for evidence of association in the largest published GWAMA for BMI (GIANT). Subsequently we performed sex-stratified analyses for these 1000 SNPs. Functional ex vivo studies on four genes ensued. Lastly, a look-up of GWAMA-derived BMI-related loci was performed in the AN GWAMA. We detected significant associations (P-values <5 × 10−5, Bonferroni-corrected P<0.05) for nine SNP alleles at three independent loci. Interestingly, all AN susceptibility alleles were consistently associated with increased BMI. None of the genes (chr. 10: CTBP2, chr. 19: CCNE1, chr. 2: CARF and NBEAL1; the latter is a region with high linkage disequilibrium) nearest to these SNPs has previously been associated with AN or obesity. Sex-stratified analyses revealed that the strongest BMI signal originated predominantly from females (chr. 10 rs1561589; Poverall: 2.47 × 10−06/Pfemales: 3.45 × 10−07/Pmales: 0.043). Functional ex vivo studies in mice revealed reduced hypothalamic expression of Ctbp2 and Nbeal1 after fasting. Hypothalamic expression of Ctbp2 was increased in diet-induced obese (DIO) mice as compared with age-matched lean controls. We observed no evidence for associations for the look-up of BMI-related loci in the AN GWAMA. A cross-trait analysis of AN and BMI loci revealed variants at three chromosomal loci with potential joint impact. The chromosome 10 locus is particularly promising given that the association with obesity was primarily driven by females. In addition, the detected altered hypothalamic expression patterns of Ctbp2 and Nbeal1 as a result of fasting and DIO implicate these genes in weight regulation
Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index
- Author
- Adair L. S.
- Adan R.
- Adan Roger A. H.
- Alavere H.
- Albrecht E.
- Alexander Graeme
- Alfredsson Lars
- Amin N.
- Anderson Carl A
- Ando Tetsuya
- Andreassen Ole A
- Ang W.
- Antel J.
- Aschauer Harald
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- Atalay M.
- Baker Jessica H
- Bandinelli S.
- Barrett Jeff C
- Barrett Jeffrey C
- Barroso I.
- Bencko Vladimir
- Benke K.
- Berenson G. S.
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- Bergmann S.
- Berrettini W.
- Berrettini Wade
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- Bierut L. J.
- Blackburn H.
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- Boni Claudette
- Boomsma D. I.
- Boraska Perica V.
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- Bradfield J. P.
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- Breen Gerome
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- Campbell H.
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- Cichon Sven
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- Mooser V.
- Morgan Linda
- Murabito J. M.
- Murray A.
- Murray J. C.
- Murray J. C.
- Murray S. S.
- Mã¤nnik Katrin
- Mã¼ller T. D.
- Nalls M. A.
- Navarro P.
- Navratilova Marie
- Nelis M.
- Nengut Suna Gumuscu
- Ness A. R.
- Nivard M.
- Nohr E. A.
- Northstone K.
- Ntalla I.
- Ntalla Ioanna
- O'Reilly P. F.
- Oken E.
- Ong K. K.
- Ong K. K.
- Oostra B. A.
- Ophoff Roel A
- Ouwehand Willem H
- Oâ\u80\u99toole Julie K
- Padyukov Leonid
- Palmer L. J.
- Palmer L. J.
- Palotie A.
- Palotie Aarno
- Panoutsopoulou K.
- Pantel Jacques
- Papezova Hana
- Pararajasingham J.
- Parker A. N.
- Parã© G.
- Peacock M.
- Pearson E. R.
- Pedersen N. L.
- Peltonen L.
- Peltonen Leena
- Peltonen Leena
- Pennell C. E.
- Pennell C. E.
- Perica Vesna Boraska
- Perry J. R.
- Pharoah P.
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- Plotnicov Kathy
- Plump A. S.
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- Porcu E.
- Potter Simon
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- Power C.
- Price T. S.
- Prokopenko I.
- Rabionet Raquel
- Raevuori Helkamaa Anu
- Rafnar T.
- Raitakari O. T.
- Rajewski Andrzej
- Ramoz Nicolas
- Rayner N. William
- Reichborn Kjennerud Ted
- Reinvang Ivar
- Rice J. P.
- Rich Stephen S
- Ridker P. M.
- Ring S. M.
- Ring Susan M
- Ripatti Samuli
- Ritchie Graham R. S.
- Rivadeneira F.
- Roberts Marion
- Rodriguez A.
- Rotondo Alessandro
- Rudan I.
- Rujescu Dan
- Rybakowski Filip
- Sala C.
- Salem R. M.
- Salomaa V.
- Sambrook Jennifer
- Sandford Richard N
- Sanna S.
- Santonastaso Paolo
- Saw S. M.
- Scherag A.
- Scherag A.
- Scherag Andrã
- Scherag Susann
- Scherer Stephen W
- Schlessinger D.
- Schmidt Ulrike
- Schork N. J.
- Schork Nicholas J
- Schosser Alexandra
- Schreiber Stefan
- Scuteri A.
- Sebert S.
- Segr㨠A. V.
- Sheerin Neil
- Shuldiner A. R.
- Siitonen N.
- Simell O.
- Simpkin Douglas
- Slachtova Lenka
- Sladek Rob
- Slagboom P. Eline
- Slof Opâ\u80\u99t Landt Margarita C. T.
- Slopien Agnieszka
- Smith A. V.
- Smith E. N.
- Soranzo N.
- Soranzo Nicole
- Soranzo Nicole
- Southam Lorraine
- Sovio U.
- Sovio U.
- Spector T. D.
- Srinivasan S. R.
- Steen Vidar M
- Stefansson K.
- Stephens Jonathan
- Stolk L.
- Strachan D. P.
- Strachan D. P.
- Strachan David P
- Streeten E. A.
- Strengman Eric
- Strober Michael
- Sulem P.
- Sullivan Patrick F
- Sunyer J.
- Szatkiewicz Jin P
- Szeszenia Dabrowska Neonila
- Sã¸rensen T. I.
- Taal H. R.
- Tachmazidou Ioanna
- Taico Chrysecolla
- Tammesoo M. L.
- Tenconi Elena
- Teo Y. Y.
- Thiering E.
- Thornton L. M.
- Thornton Laura M
- Thorsteinsdottir U.
- Tiesler C.
- Tikkanen E.
- Timpson N. J.
- Toniolo D.
- Tortorella Alfonso
- Tozzi Federica
- Trace Sara E
- Treasure Janet
- Treasure Janet
- Tryggvadottir L.
- Tschã¶p M. H.
- Tsitsika Artemis
- Tsui K.
- Tyrer J.
- Tziouvas Konstantinos
- Uda M.
- Uitterlinden A. G.
- Uitterlinden A. G.
- Ulivi S.
- Valcã¡rcel B.
- van Beijsterveldt T.
- van Dam R. M.
- van Duijn C. M.
- Van Elburg A.
- van Elburg Annemarie A
- Van Furth Eric F.
- van Meurs J. B.
- van Wingerden S. H.
- Vannberg Frederik O
- Versini Audrey
- Visser J. A.
- Volckmar A. L.
- Vollenweider P.
- Waeber G.
- Wagner Gudrun
- Wareham N. J.
- Warrington M.
- Warrington N. M.
- Waterworth D. M.
- Weedon M. N.
- White S.
- Whittaker Pamela
- Wichmann H. E.
- Wichmann H. Erich
- Widen E.
- Widã©n E.
- Widã©n Elisabeth
- Willemsen G.
- Willemsen G.
- Wilson J. F.
- Wilson J. F.
- Winkler T. W.
- Woodside D. Blake
- Wright A. F.
- Yaghootkar H.
- Yilmaz Zeynep
- Young L.
- Zeggini E.
- Zeggini E.
- Zeggini Eleftheria
- Zeggini Eleftheria
- Zerwas Stephanie
- Zgaga L.
- Zhai G.
- Zhao J. H.
- Zhuang W. V.
- Zipfel S.
- Zipfel Stephan
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2017
- Field of study
The maintenance of normal body weight is disrupted in patients with anorexia nervosa (AN) for prolonged periods of time. Prior to the onset of AN, premorbid body mass index (BMI) spans the entire range from underweight to obese. After recovery, patients have reduced rates of overweight and obesity. As such, loci involved in body weight regulation may also be relevant for AN and vice versa. Our primary analysis comprised a cross-trait analysis of the 1000 single-nucleotide polymorphisms (SNPs) with the lowest P-values in a genome-wide association meta-analysis (GWAMA) of AN (GCAN) for evidence of association in the largest published GWAMA for BMI (GIANT). Subsequently we performed sex-stratified analyses for these 1000 SNPs. Functional ex vivo studies on four genes ensued. Lastly, a look-up of GWAMA-derived BMI-related loci was performed in the AN GWAMA. We detected significant associations (P-values <5 × 10-5, Bonferroni-corrected P<0.05) for nine SNP alleles at three independent loci. Interestingly, all AN susceptibility alleles were consistently associated with increased BMI. None of the genes (chr. 10: CTBP2, chr. 19: CCNE1, chr. 2: CARF and NBEAL1; the latter is a region with high linkage disequilibrium) nearest to these SNPs has previously been associated with AN or obesity. Sex-stratified analyses revealed that the strongest BMI signal originated predominantly from females (chr. 10 rs1561589; Poverall: 2.47 × 10-06/Pfemales: 3.45 × 10-07/Pmales: 0.043). Functional ex vivo studies in mice revealed reduced hypothalamic expression of Ctbp2 and Nbeal1 after fasting. Hypothalamic expression of Ctbp2 was increased in diet-induced obese (DIO) mice as compared with age-matched lean controls. We observed no evidence for associations for the look-up of BMI-related loci in the AN GWAMA. A cross-trait analysis of AN and BMI loci revealed variants at three chromosomal loci with potential joint impact. The chromosome 10 locus is particularly promising given that the association with obesity was primarily driven by females. In addition, the detected altered hypothalamic expression patterns of Ctbp2 and Nbeal1 as a result of fasting and DIO implicate these genes in weight regulation
Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index
- Author
- Adamo P. (Pio) d'
- Adan R. (R.)
- Alavere H. (Helene)
- Albrecht E. (Eva)
- Alexander G. (Graeme)
- Alfredsson L. (Lars)
- Amin N. (Najaf)
- Amin N. (Najaf)
- Anderson C.A. (Carl A)
- Ando T. (Tetsuya)
- Ang W.Q. (Wei)
- Antel J. (J.)
- Aspelund T. (T.)
- Aspelund T. (Thor)
- Atalay M. (Mustafa)
- Baker J.H. (Jessica H)
- Barrett J.C. (Jeffrey)
- Barroso I.E. (Inês)
- Beijsterveldt C.E.M. (Toos) van
- Bencko V. (Vladimir)
- Benke K. (K.)
- Berenson G. (Gerald)
- Bergen A.W. (Andrew)
- Bergen N. (N.)
- Bergmann S.M. (Sven)
- Berrettini W. (Wade)
- Berry D. (Diane)
- Bierut L.J. (L. J.)
- Bierut L.J. (Laura)
- Blackburn H. (Hannah)
- Boerwinkle E. (E.)
- Boerwinkle E.A. (Eric)
- Boni C. (Claudette)
- Boomsma D.I. (Dorret)
- Boraska Perica V. (V.)
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- Wichmann H.E. (Heinz Erich)
- Widen E.
- Widen E. (E.)
- Willemsen G.A.H.M. (Gonneke)
- Wilson J.F. (J. F.)
- Wingerden S. (Sophie) van
- Winkler T.W. (Thomas W.)
- Woodside D.B. (D Blake)
- Wright A.F. (Alan)
- Yaghootkar H. (H.)
- Yilmaz Z. (Zeynep)
- Young L. (L.)
- Zeggini E. (Eleftheria)
- Zerwas S. (Stephanie)
- Zgaga L. (L.)
- Zhai G. (G.)
- Zhao J.H. (J. H.)
- Zhuang W.V. (W. V.)
- Zipfel S. (S.)
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/02/2017
- Field of study
The maintenance of normal body weight is disrupted in patients with anorexia nervosa (AN) for prolonged periods of time. Prior to the onset of AN, premorbid body mass index (BMI) spans the entire range from underweight to obese. After recovery, patients have reduced rates of overweight and obesity. As such, loci involved in body weight regulation may also be relevant for AN and vice versa. Our primary analysis comprised a cross-trait analysis of the 1000 single-nucleotide polymorphisms (SNPs) with the lowest P-values in a genome-wide association meta-analysis (GWAMA) of AN (GCAN) for evidence of association in the largest published GWAMA for BMI (GIANT). Subsequently we performed sex-stratified analyses for these 1000 SNPs. Functional ex vivo studies on four genes ensued. Lastly, a look-up of GWAMA-derived BMI-related loci was performed in the AN GWAMA. We detected significant associations (P-values <5 × 10-5, Bonferroni-corrected P<0.05) for nine SNP alleles at three independent loci. Interestingly, all AN susceptibility alleles were consistently associated with increased BMI. None of the genes (chr. 10: CTBP2, chr. 19: CCNE1, chr. 2: CARF and NBEAL1; the latter is a region with high linkage disequilibrium) nearest to these SNPs has previously been associated with AN or obesity. Sex-stratified analyses revealed that the strongest BMI signal originated predominantly from females (chr. 10 rs1561589; Poverall: 2.47 × 10-06/Pfemales: 3.45 × 10-07/Pmales: 0.043). Functional ex vivo studies in mice revealed reduced hypothalamic expression of Ctbp2 and Nbeal1 after fasting. Hypothalamic expression of Ctbp2 was increased in diet-induced obese (DIO) mice as compared with age-matched lean controls. We observed no evidence for associations for the look-up of BMI-related loci in the AN GWAMA. A cross-trait analysis of AN and BMI loci revealed variants at three chromosomal loci with potential joint impact. The chromosome 10 locus is particularly promising given that the association with obesity was primarily driven by females. In addition, the detected altered hypothalamic expression patterns of Ctbp2 and Nbeal1 as a result of fasting and DIO implicate these genes in weight regulation
Factors associated with COVID-19-related death in people with rheumatic diseases: results from the COVID-19 Global Rheumatology Alliance physician-reported registry
- Author
- Aase Hensvold
- Alexander Pfeil
- Alexandre TJ Maria
- Alexandre Virone
- Alice Tison
- Ambre Hittinger-Roux
- Amelie Servettaz
- and Kurt Zimmerman
- Andreas Krause
- Angel AC Ortiz
- Angela Dahle
- Anja Strangfeld
- Ann Knight
- Anna Zanetti
- Anne Regierer
- Anne Wolff
- Anne-Marie Chassin-Trubert
- Antoine Froissart
- Archibald Skemp
- Ariel Salinas
- Arsène Mekinian
- Arundathi Jayatilleke
- Aude Giraud-Morelet
- Babur Salim
- Beatriz Zaueta
- Bernard Combe
- Bernd Raffeiner
- Bimba F Hoyer
- Brahim Dahou
- Brigitte Dupré
- Bruno Fautrel
- Byung Ban
- Caludia Lomater
- Carlo A Scirè
- Caroline M Jones
- Cassandra Calabrese
- Catherine Michel
- Ceciclia Nalli
- Chiara Crotti
- Christelle Sordet
- Christian Roux
- Christof Specker
- Christophe Hudry
- Christophe Leroux
- Christophe Richez
- Cinzia Rotondo
- Claire Vandevelde
- Clémentine Rousselin
- Concetta Lamore
- COVID-19 Global Rheumatology Alliance
- COVID-19 Global Rheumatology Alliance Consortium Collaborators: COVID-19 Global Rheumatology Alliance Consortium
- Daniel Wendling
- David Karp
- David Vega
- Davide Carboni
- Derrick Todd
- Deshiré Alpízar-Rodríguez
- Diana C Rosete
- Diana O'Kane
- Diane Rouzaud
- Diogo Almeida
- Douglas White
- Edoardo Cipolletta
- Edouard Pertuiset
- Eduardo Martín
- Elena Bartoloni-Bocci
- Elena Nikiphorou
- Elizabeth Macphie
- Elizabeth Warner
- Elliot Rosenstein
- Elodie Constant
- Elsa F Mateus
- Elvira Decker
- Emily Pfeifer
- Emily Sirotich
- Emma Grenholm
- Emmanuel Ledoult
- Enrique Giraldo
- Eric Hachulla
- Eric Ruderman
- Erick AZ Tehozol
- Esther Ebstein
- Ettore Silvagni
- Evangeline Scopelitis
- Ezzati Fatemeh
- Faizah Siddique
- Fanny Domont
- Fatemah Abutiban
- Fedra Irazoque
- Florenzo Iannone
- Francesco Campanaro
- Francinne M Ribeiro
- Franck Grados
- Franco Franceschini
- Frederik N Albach
- Frédéric Liote
- Gabriela MG Melgar
- Gabriela Schmajuk
- Gauthier Morel
- Gaëlle Clavel
- Giacomo Guidelli
- Gianpiero Landolfi
- Gilbert Kepecs
- Giovanni Zanframundo
- Gloria Dallagiacoma
- Greta Carrara
- Guillermo Quiceno
- Hammad Bajwa
- Hanns-Martin Lorenz
- Hendrik Schulze-Koops
- Hesham Hamoud
- Hubert Marotte
- Ilaria Tinazzi
- Isabelle Kone-Paut
- Isabelle Lambrecht
- Isabelle Melki
- Jacques Morel
- Javier Bachiller-Corral
- Jean W Liew
- Jean-Paul Larbre
- Jeanine S Giraudet-Le Quitrec
- Jeffrey A Sparks
- Jeffrey Sparks
- Jeffrey Wilson
- Jennifer Morgan
- Jenny Tyler
- Jerald Zakem
- Jinoos Yazdany
- JoAnn Zell
- Jody Hargrove
- Joerg Henes
- Johan Back
- Jonathan S Hausmann
- Joris Galland
- Jose C Esteban
- Jose G Puerta
- Juan J Alegre-Sancho
- Jutta G Richter
- Jérémie Sellam
- Jérôme Avouac
- Karen T Toribio
- Kathryn Dao
- Kimme L Hyrich
- Kirsty Devine
- Klaus Krüger
- Kristen Young
- Kristin D'Silva
- Laura Andreoli
- Laura Chadwick
- Laura Trupin
- Laure Gossec
- Laurent Messer
- Leanna Wise
- Lianne Kearsley-Fleet
- Lindsay Jacobsohn
- Lingli Dong
- Lionnel Spielmann
- Loreto Carmona
- Lotta Ljung
- Luca Quartuccio
- Lucia Fusi
- Lucy Thornton
- Lui Cajas
- Luigi Sinigaglia
- Mahdi Vojdanian
- Manuel Ugarte-Gil
- Marcelo Pinheiro
- Maren Hilton
- Maria del Martin
- Maria J Santos
- Maria Rato
- Marie Desmurs
- Marie-Eve Colette-Cedoz
- Marie-Noelle Paris-Havard
- Marina R Gabayet
- Marion Hermet
- Markus Rihl
- Marta Caprioli
- Marta Riva
- Martin Schäfer
- Maryam Dastmalchi
- Mathilde Devaux
- Maurizio Benucci
- Melanie Winter
- Melissa Harvey
- Micaela Fredi
- Miguel Bernardes
- Mikaël Ebbo
- Milena A Gianfrancesco
- Montserrat C Coro
- Myriam Renard
- Naomi Serling-Boyd
- Nasra Al-Adhoubi
- Natalia de la Torre-Rubio
- Nathalie Costedoat-Chalumeau
- Nathalie Tieulié
- Neil Kramer
- Nicholas Lebedoff
- Nicole Daver
- Nicoletta Romeo
- Ozan C Icacan
- Paola Faggioli
- Pascal Chazerain
- Pascal Claudepierre
- Patrice Cacoub
- Patricia Katz
- Paul Sufka
- Pedro M Machado
- Peer Aries
- Philip C Robinson
- Philippe Goupille
- Pierre Lafforgue
- Pierre-Marie Duret
- Rachael Flood
- Rachel Wallwork
- Raphaele Seror
- Raphaël Borie
- Rebecca Grainger
- Rebecca Hasseli
- Reinhard E Voll
- Renaud Felten
- René-Marc Flipo
- Richard Conway
- Rita C Machado
- Robert Quinet
- Robin Dhote
- Rosaria Salerno
- Rosario Foti
- Rossella Reggia
- Ruth Costello
- Sabine Revuz
- Samar Al-Emadi
- Samir Patel
- Sara Baig
- Sarah Al-Adely
- Sasha Dunt
- Saskia Lawson-Tovey
- Sebastián Ibáñez
- Servet Akar
- Sheila O'Reilly
- Simone Parisi
- Sophie Georgin-Lavialle
- Sophie Govindaraju-Audouard
- Sophie Lahalle
- Sophie Trijau
- Soumaya El Mahou
- Stephanie Werner
- Su-Ann Yeoh
- Suleman Bhana
- Susan Leonard
- Sushama Mody
- Sylvain La Batide Alanore
- Sébastien Rivière
- Séverine Guillaume-Czitrom
- Tameka Webb-Detiege
- Tatiana S Rodriguez-Reyna
- Thao Pham
- Theodore Fields
- Thierry Thomas
- Tiffany Hsu
- Tim Schmeiser
- Ulf Müller-Ladner
- Urs Hartmann
- Ursula Warzocha
- Valérie Devauchelle-Pensec
- Vernon Berglund
- Vincent Langlois
- Vincent Sobanski
- Violaine Foltz
- Véronique Belin
- Véronique Gaud-Listrat
- Walter Dorman
- Wendy Costello
- William Davis
- Xavier Chevalier
- Xochitl Jimenez
- Yannick Dieudonné
- Zachary S Wallace
- Zara Izadi
- Zara Izadi
- Publication venue
- 'BMJ'
- Publication date
- 01/01/2021
- Field of study
Objectives: To determine factors associated with COVID-19-related death in people with rheumatic diseases.
Methods: Physician-reported registry of adults with rheumatic disease and confirmed or presumptive COVID-19 (from 24 March to 1 July 2020). The primary outcome was COVID-19-related death. Age, sex, smoking status, comorbidities, rheumatic disease diagnosis, disease activity and medications were included as covariates in multivariable logistic regression models. Analyses were further stratified according to rheumatic disease category.
Results: Of 3729 patients (mean age 57 years, 68% female), 390 (10.5%) died. Independent factors associated with COVID-19-related death were age (66-75 years: OR 3.00, 95% CI 2.13 to 4.22; >75 years: 6.18, 4.47 to 8.53; both vs ≤65 years), male sex (1.46, 1.11 to 1.91), hypertension combined with cardiovascular disease (1.89, 1.31 to 2.73), chronic lung disease (1.68, 1.26 to 2.25) and prednisolone-equivalent dosage >10 mg/day (1.69, 1.18 to 2.41; vs no glucocorticoid intake). Moderate/high disease activity (vs remission/low disease activity) was associated with higher odds of death (1.87, 1.27 to 2.77). Rituximab (4.04, 2.32 to 7.03), sulfasalazine (3.60, 1.66 to 7.78), immunosuppressants (azathioprine, cyclophosphamide, ciclosporin, mycophenolate or tacrolimus: 2.22, 1.43 to 3.46) and not receiving any disease-modifying anti-rheumatic drug (DMARD) (2.11, 1.48 to 3.01) were associated with higher odds of death, compared with methotrexate monotherapy. Other synthetic/biological DMARDs were not associated with COVID-19-related death.
Conclusion: Among people with rheumatic disease, COVID-19-related death was associated with known general factors (older age, male sex and specific comorbidities) and disease-specific factors (disease activity and specific medications). The association with moderate/high disease activity highlights the importance of adequate disease control with DMARDs, preferably without increasing glucocorticoid dosages. Caution may be required with rituximab, sulfasalazine and some immunosuppressants
The LHCb upgrade I
- Author
- Aaij Roel
- Abdelmotteleb Ahmed Sameh Wagih
- Abellan Beteta Carlos
- Abudinén Fernando Jesus
- Achard Cyrille
- Ackernley Thomas
- Adeva Bernardo
- Adinolfi Marco
- Adlarson Patrik Harri
- Afsharnia Hossein
- Agapopoulou Christina
- Aidala Christine Angela
- Ajaltouni Ziad
- Akar Simon
- Akiba Kazuyoshi
- Albicocco Pietro
- Albrecht Johannes
- Alessio Federico
- Alexander Michael
- Alfonso Albero Alejandro
- Aliouche Zakariya
- Alvarez Cartelle Paula
- Amalric Renaud
- Amato Sandra
- Amey Jake Lewis
- Amhis Yasmine
- An Liupan
- Anderlini Lucio
- Andersson Martin
- Andreani Alessandro
- Andreianov Aleksei
- Andreotti Mirco
- Andreou Dimitra
- Andrews Jason
- Anelli Mario
- Anjam Andrea
- Ao Dong
- Archilli Flavio
- Arnaud Kevin
- Artamonov Alexander
- Artuso Marina
- Ashby Joe
- Aslanides Elie
- Atzeni Michele
- Audurier Benjamin
- Ayres Rocha Diogo
- Bachiller Perea Irene
- Bachmann Sebastian
- Bachmayer Marie
- Back John
- Bailly-reyre Aurelien
- Baladron Rodriguez Pablo
- Balagura Vladislav
- Balbi Gabriele
- Baldini Wander
- Balla Alessandro
- Baltazar Michel
- Band Hans
- Baptista de Souza Leite Juan
- Barbetti Matteo
- Barclay Paul
- Barlow Roger
- Barsuk Sergey
- Barter William
- Bartolini Matteo
- Baryshnikov Fedor
- Basels Jan-Marc
- Bassi Giovanni
- Baszczyk Mateusz
- Batista Lopes Joao Carlos
- Batsukh Baasansuren
- Battig Alexander
- Bay Aurelio
- Beck Anja
- Becker Maik
- Bedeschi Franco
- Bediaga Ignacio
- Beigbeder-Beau Christophe
- Beiter Andrew
- Belin Samuel
- Bellee Violaine
- Belous Konstantin
- Belov Ilia
- Belyaev Ivan
- Ben-Haim Eli
- Benane Gaya
- Bencivenni Giovanni
- Benettoni Massimo
- Berezhnoy Alexander
- Bernard Florian
- Bernet Andres Sergi
- Bernet Roland
- Berninghoff Daniel
- Bernstein Harris Conan
- Bertella Claudia
- Bertolin Alessandro
- Betancourt Christopher
- Betti Federico
- Bezshyiko Ia.
- Bezshyiko Iaroslava
- Bezshyyko Oleg
- Bhasin Srishti
- Bhom Jihyun
- Bian Lingzhu
- Bieker Martin Stefan
- Biesuz Nicolo Vladi
- Billoir Pierre
- Biolchini Alice
- Birch Matthew
- Bishop Fionn Caitlin Ros
- Bitadze Alexander
- Bizzeti Andrea
- Blago Michele Piero
- Blake Thomas
- Blanc Frederic
- Blank Jonah Evan
- Blusk Steven
- Bobulska Dana
- Bochin Boris
- Boelhauve Julian Alexander
- Boente Garcia Oscar
- Boettcher Thomas
- Bogdanova Galina
- Boiaryntseva Ianina
- Boldyrev Alexey
- Bolognani Carolina
- Bolzonella Riccardo
- Bondar Nikolay
- Booth Michael Jack
- Borgato Federica
- Borghi Silvia
- Borsato Martino
- Borsuk Jozef Tomasz
- Boterenbrood Henk
- Bouchiba Sonia Amina
- Bowcock Themistocles
- Boyaryntsev Andriy
- Boyer Alexandre
- Bozzi Concezio
- Bradley Matthew John
- Braun Svende
- Brea Rodriguez Alexandre
- Bregliozzi Giuseppe
- Bridges Kieran
- Briere Matthieu Marc Joel
- Brock Matthew
- Brodski Michael
- Brodzicka Jolanta
- Brossa Gonzalo Arnau
- Brown Charles
- Brown James David
- Brummitt Amanda Jayne
- Brundu Davide
- Brunetti Laurent
- Buda Lou
- Buonaura Annarita
- Buonincontri Laura
- Burke Aodhan Tomas
- Burmistrov Leonid
- Burr Christopher
- Bursche Albert
- Butkevich Anatoly
- Butter Jordy Sebastiaan
- Buytaert Jan
- Byczynski Wiktor
- Cachemiche Jean-Pierre
- Cadeddu Sandro
- Cai Hao
- Caillet Amelie
- Calabrese Roberto
- Calefice Lukas
- Calegari Didier
- Cali Stefano
- Calvi Marta
- Calvo Gomez Miriam
- Campana Pierluigi
- Campora Perez Daniel Hugo
- Campoverde Quezada Angel Fernando
- Canfer Simon
- Capelli Simone
- Capriotti Lorenzo
- Carassiti Vittore
- Carbone Angelo
- Carbone Antonio
- Cardinale Roberta
- Cardini Alessandro
- Carletti Maurizio
- Carniti Paolo
- Carroll John
- Carus Leon David
- Casais Vidal Adrian
- Caspary Rowina
- Casse Gianluigi
- Cattaneo Marco
- Cavallero Giovanni
- Cavallini Viola
- Ceelie Lukas
- Celani Sara
- Cerasoli Jacopo
- Cervenkov Daniel
- Cesare Sara
- Chadaj Bernard
- Chadwick Abbie Jane
- Chahrour Ibrahim
- Chanal Herve
- Chapman Matthew George
- Charles Matthew
- Charpentier Ph.
- Charpentier Philippe
- Chaumat Vincent Jacques
- Chavez Barajas Carlos Alberto
- Chefdeville Maximilien
- Chen Chen
- Chen Shanzhen
- Chernov Aleksei
- Chernov Evgeny
- Chernyshenko Serhii
- Chiozzi Stefano
- Chobanova Veronika
- Cholak Serhii
- Chrzaszcz Marcin
- Chubykin Aleksei
- Chulikov Vladimir
- Ciambrone Paolo
- Cicala Maria Flavia
- Cid Vidal Xabier
- Ciezarek Gregory
- Cifra Pierfrancesco
- Citterio Mauro
- Ciullo Giuseppe
- Clark Keith
- Clarke P.E.L.
- Clemencic Marco
- Cliff Harry
- Closier Joel
- Cobbledick John Leslie
- Coco Victor
- Coelli Simone
- Cogan Julien
- Cogneras Eric
- Cojocariu Lucian
- Collins Paula
- Colombo Tommaso
- Congedo Liliana
- Conti Nadim
- Contu Andrea
- Cooke Naomi
- Corredoira Imanol
- Corti Gloria
- Cotta Ramusino Angelo
- Couturier Benjamin
- Cowan Greig
- Craik Daniel Charles
- Cruz Torres Melissa Maria
- Currie Robert
- D'Ambrosio Carmelo
- d'Argent Philippe
- Da Silva Cesar Luiz
- Dadabaev Shakhzod
- Dai Lingyun
- Dai Xinchen
- Dall'Occo Elena
- Dalseno Jeremy
- Damen Antonius
- Daniel Jessy
- Danilina Anna
- Daudon Francois
- Davies Jonathan Edward
- Davis Adam
- Davis Jeffrey
- De Aguiar Francisco Oscar
- De Benedetti Federico
- de Boer Jan
- De Bruyn Kristof
- De Capua Stefano
- De Cian Michel
- De Freitas Carneiro Da Graca Ulisses
- De Lucia Erika
- De Miranda Jussara
- de Oliveira Rui
- De Paula Leandro
- De Roo Krista
- De Serio Marilisa
- De Simone Dario
- De Simone Patrizia
- De Vellis Fabio
- de Vries Jacco
- De Wit Espen
- Dean Cameron Thomas
- Debernardis Francesco
- Decamp Daniel
- Deckenhoff Mirko
- Dedu Vlad-George
- Del Buono Luigi
- Delaney Blaise
- Dembinski Hans Peter
- Denis Cindy
- Denysenko Vadym
- Deschamps Olivier
- Dettori Francesco
- Dey Biplab
- Di Bari Daniele
- Di Nezza Pasquale
- Diachkov Igor
- Didenko Sergey
- Dieste Maronas Lorena
- Dijkstra Hans
- Ding Shuchong
- Dobishuk Vasyl
- Doets Martin
- Doherty Frederick
- Dolmatov Aleksandr
- Domke Matthias
- Dong Chenzhi
- Donohoe Amanda May
- Dordei Francesca
- Dorosz Piotr
- dos Reis Alberto
- Douglas Lauren
- Downes Anthony Gavin
- Duarte Olivier
- Duda Piotr Jakub
- Dudek Maciej Wojciech
- Dufour Laurent
- Duk Viacheslav
- Dumps Raphael
- Durante Paolo
- Duras Maciej
- Durham John Matthew
- Dutta Deepanwita
- Duval Pierre-Yves
- Dziewiecki Michal
- Dziurda Agnieszka
- Dzyuba Alexey
- Easo Sajan
- Egede Ulrik
- Egorychev Victor
- Eirea Orro Caetano
- Eisenhardt Stephan
- Ejopu Enoch
- Ek-In Surapat
- Ekelhof Robert
- Eklund Lars
- Elashri Mohamed
- Ellbracht Jan Hendrik
- Elvin Andrew
- Ely Scott
- Ene Alexandru
- Epple Eliane
- Escher Stephan
- Eschle Jonas Nathanael
- Esen Sevda
- Evans Timothy
- Fabiano Federica
- Falcao Lucas
- Fan Yanting
- Fang Bo
- Fantini Lisa
- Faria Maria
- Farry Stephen
- Fazzini Davide
- Felkowski L.F.
- Felkowski Lukasz Jerzy
- Feo Mauricio
- Fernandez Declara Placido
- Fernandez Gomez Miguel
- Fernandez Prieto A.
- Fernez Alex Daniel
- Ferrari Fabio
- Ferreira Lopes Lino
- Ferreira Rodrigues Fernando
- Ferreira Rodrigo
- Ferreres Sole Silvia
- Ferrillo Martina
- Ferro-Luzzi Massimiliano
- Filippov Sergey
- Fini Rosa Anna
- Fiorini Massimiliano
- Firlej Miroslaw
- Fischer K.M.
- Fischer Kamil Leszek
- Fitzgerald Dillon Scott
- Fitzpatrick Conor
- Fiutowski Tomasz
- Fleuret Frederic
- Flores Leyre
- Fontana Marianna
- Fontanelli Flavio
- Forty Roger
- Foulds-Holt Daniel
- Fournier Cedric
- Franco Lima Vinicius
- Franco Sevilla Manuel
- Frank Markus
- Franzoso Edoardo
- Frau Giulia
- Freestone Julian
- Frei Christoph
- Frei Raymond
- Frelier Jeffrey
- Friday David Anthony
- Frontini Luca
- Fu Jinlin
- Fuehring Quentin
- Fulghesu Tommaso
- Fuzipeg Claire
- Gabriel Emmy
- Galati Giuliana
- Galati Maria Domenica
- Galka M.A.
- Gallas Torreira Abraham
- Galli Domenico
- Gallorini Stefano
- Gambetta Silvia
- Gan Yuyue
- Gandelman Miriam
- Gandini Paolo
- Gao Rui
- Gao Yang
- Gao Yuanning
- Garau Michela
- Garcia Martin Luis Miguel
- Garcia Moreno Paula
- Garcia Plana Beatriz
- Garcia Rosales Felipe Andres
- García Pardiñas Julián
- Garrido Lluis
- Garroum Nabil
- Garsed Philip John
- Gascon David
- Gaspar Clara
- Gasq Christine
- Gatta Maurizio
- Gavardi Laura
- Gebolis Piotr Mieczyslaw
- Geertsema Robbert Erik
- Gerick David
- Gerken Louis Lenard
- Germann Danielle Abriana
- Gersabeck Evelina
- Gersabeck Marco
- Gershon Timothy
- Getz Stanislav A.
- Giambastiani Luca
- Gibson Valerie
- Giemza Henryk Karol
- Gilman Alexander Leon
- Giovannetti Matteo
- Gioventù Alessandra
- Girard Olivier Göran
- Gironella Gironell Pere
- Giugliano Carmen
- Giza Maciej Artur
- Gizdov Konstantin
- Gkougkousis Evangelos Leonidas
- Gligorov Vladimir
- Golinka-Bezshyyko Larysa
- Golobardes Elisabet
- Golubkov Dmitry
- Golutvin Andrey
- Gomes Alvaro
- Gomez Fernandez Sergio
- Goncalves Abrantes Fernanda
- Goncerz Mateusz
- Gong Guanghua
- Gorelov Igor Vladimirovich
- Gotti Claudio
- Grabowski Jascha Peter
- Grammatico Thomas
- Granado Cardoso Luis Alberto
- Grant Fiona
- Graugés Eugeni
- Graverini Elena
- Graziani Giacomo
- Grecu Alexandru Tudor
- Greeven Lex Marinus
- Greim Roman
- Grieser Nathan Allen
- Grillo Lucia
- Gromov Sergey
- Gromov Vladimir
- Grub Nathalie
- Gruberg Cazon Barak Raimond
- Grynyov Boris
- Gu Chenxi
- Guarise Marco
- Guerin Stephen
- Guittiere Manuel
- Gushchin Evgeny
- Guth Andreas
- Guz Yury
- Gys Thierry
- Göbel Carla
- Günther Paul Andre
- Hachon Frederic
- Hadavizadeh Thomas
- Hadjivasiliou Christos
- Haefeli Guido
- Haen Christophe
- Haimberger Jakob
- Haines Susan
- Halewood-leagas Tabitha
- Halvorsen Marius Maehlum
- Hamilton Phoebe Meredith
- Hammerich Jan
- Hamrat Sonia
- Han Qundong
- Han Xiaoxue
- Hansen Eva Brottmann
- Hansmann-Menzemer Stephanie
- Hao Lei
- Harnew Neville
- Harrison Thomas
- Hasse Christoph
- Hatch Mark
- He Jibo
- Heijhoff Kevin
- Hemmer Frederic
- Henderson Conor
- Henderson Riley Dylan Leslie
- Hennequin Arthur Marius
- Hennessy Karol
- Henry Louis
- Herd James Daniel
- Herold Tobias
- Heuel Johannes
- Hicheur Adlène
- Hill Donal
- Hilton Martha
- Hoft Gino Timothy
- Hollitt Sophie
- Hopchev Plamen Hristov
- Hornberger Oliver
- Horswill Joshua Ethan
- Hou Ruiwen
- Hou Yingrui
- Hu Jiangqiao
- Hu Jifeng
- Hu Wenhua
- Hu Xiaofan
- Huang Wenqian
- Huang Xiaotao
- Hulsbergen Wouter
- Hummel Stefan
- Hunter Ross John
- Hushchyn Mikhail
- Hutanu Ovidiu Emanuel
- Hutchcroft David
- Hynds Daniel
- Ibis Philipp
- Idzik Marek
- Ilin Dmitrii
- Ilten Philip
- Inglessi Alexander
- Iniukhin Aleksandr
- Insa Christophe
- Ishteev Artur
- Ivshin Kuzma
- Jacobsson Richard
- Jage Hendrik
- Jaimes Elles Sergio Javier
- Jakobsen Sune
- Jamet Olivier
- Jans Eddy
- Jashal Brij Kishor
- Jaspers Michiel
- Jawahery Abolhassan
- Jevaud Michel
- Jevtic Vukan
- Jiang Emily Kaiyin
- Jiang Xiaojie
- Jiang Yi
- John Dimitri
- John Malcolm
- Johnson Daniel
- Jones Christopher
- Jones Thomas Peter
- Jost Beat
- Jurik Nathan
- Juszczak Izabela
- Kandybei Sergii
- Kang Youen
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- Wu Jie
- Wyllie Kenneth
- Xiang Zhiyu
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- Xu Menglin
- Xu Qingnian
- Xu Zehua
- Xu Zhihao
- Yang Di
- Yang Shuangli
- Yang Xueting
- Yang Youhua
- Yang Zhenwei
- Yang Zishuo
- Yeomans Lauren Emma
- Yeroshenko Vsevolod
- Yeung Ho Yin Dereck
- Yin Hang
- Yu Jiesheng
- Yuan Xuhao
- Zaffaroni Ettore
- Zavertyaev Mikhail
- Zdybal Milosz
- Zenaiev Oleksandr
- Zeng Ming
- Zhang Chenjia
- Zhang Dongliang
- Zhang Liming
- Zhang Shulei
- Zhang Shunan
- Zhang Yanxi
- Zhang Yu
- Zhao Ya
- Zharkova Alina
- Zhelezov Alexey
- Zheng Yangheng
- Zhou Tianwen
- Zhou Xiaokang
- Zhou Yixiong
- Zhovkovska Valeriia
- Zhu Xianglei
- Zhu Xiaoyu
- Zhu Zhanwen
- Zhukov Valery
- Zivkovic Vladimir
- Zou Quan
- Zucchelli Stefano
- Zuliani Davide
- Zunica Gianluca
- Zvyagintsev Sergey
- Publication venue
- HAL CCSD
- Publication date
- 17/05/2023
- Field of study
International audienceThe LHCb upgrade represents a major change of the experiment. The detectors have been almost completely renewed to allow running at an instantaneous luminosity five times larger than that of the previous running periods. Readout of all detectors into an all-software trigger is central to the new design, facilitating the reconstruction of events at the maximum LHC interaction rate, and their selection in real time. The experiment's tracking system has been completely upgraded with a new pixel vertex detector, a silicon tracker upstream of the dipole magnet and three scintillating fibre tracking stations downstream of the magnet. The whole photon detection system of the RICH detectors has been renewed and the readout electronics of the calorimeter and muon systems have been fully overhauled. The first stage of the all-software trigger is implemented on a GPU farm. The output of the trigger provides a combination of totally reconstructed physics objects, such as tracks and vertices, ready for final analysis, and of entire events which need further offline reprocessing. This scheme required a complete revision of the computing model and rewriting of the experiment's software