An Evaluation of Herbicides for Broadleaf-Weed Control in Rapeseed: Efficacy, Phytotoxicity, and Soil Persistence Studies

At the recommended rates (1.0 lb/A for trifluralin, ethalfluralin, EL5261; 0.75 lb/A for dinitramine; 1.2 lb/A for nitrofen), none of the herbicides we evaluated in these studies reduced rapeseed stands, yields, or test weights. However, at higher rates (1. 5, 3.0 lb A), dinitramine reduced rapeseed stands, but this did not result in decreased yields. None of the other herbicides reduced rapeseed stand, yield, or test weights when applied at up to four times the recommended rate. No trifluralin residues were detected in rapeseed whole-plant or seed samples. All of the herbicides provided adequate control of common lambsquarters (Chenopodium album L.). Corn spurry (Spergula arvensis L.) was controlled by trifluralin. ethalfluralin. EL-5261, and nitrofen. All of the herbicides except nitrofen controlled chickweed [Stellaria media (L.) Cyrillo]. In 1979, 51 per cent of the trifluralin applied remained at the end of the growing season in one study while 26 per cent remained in another study. The rate of degradation at three sites in 1979 were as follows (greatest to least); Delta Junction, Matanuska Valley, Fairbanks. Degradation rates of trifluralin were not significantly different in three soil types or at two different application rates. Trifluralin showed no signs of leaching through the soil profile. In 1981, 25 per cent of the trifluralin, 8 per cent of the ethalfluralin, and 24 per cent of the EL-5261 applied remained at the end of the growing season. Despite the relatively long persistence of these preplant, incorporated herbicides, yields and test weights of barley planted in succeeding years were not reduced. A benefit of these persistent residues was control of broadleaf weeds in the succeeding barley crop

Evolution and complexity: the double-edged sword

We attempt to provide a comprehensive answer to the question of whether, and when, an arrow of complexity emerges in Darwinian evolution. We note that this expression can be interpreted in different ways, including a passive, incidental growth, or a pervasive bias towards complexification. We argue at length that an arrow of complexity does indeed occur in evolution, which can be most reasonably interpreted as the result of a passive trend rather than a driven one. What, then, is the role of evolution in the creation of this trend, and under which conditions will it emerge? In the later sections of this article we point out that when certain proper conditions (which we attempt to formulate in a concise form) are met, Darwinian evolution predictably creates a sustained trend of increase in maximum complexity (that is, an arrow of complexity) that would not be possible without it; but if they are not, evolution will not only fail to produce an arrow of complexity, but may actually prevent any increase in complexity altogether. We conclude that, with regard to the growth of complexity, evolution is very much a double-edged sword

An analysis of ultraviolet spectra of Extreme Helium Stars and new clues to their origins

Abundances of about 18 elements including the heavy elements Y and Zr are determined from Hubble Space Telescope Space Telescope Imaging Spectrograph ultraviolet spectra of seven extreme helium stars (EHes): LSE 78, BD+10 2179, V1920 Cyg, HD 124448, PV Tel, LS IV -1 2, and FQ Aqr. New optical spectra of the three stars -- BD+10 2179, V1920 Cyg, and HD 124448 were analysed. The abundance analyses is done using LTE line formation and LTE model atmospheres especially constructed for these EHe stars. The stellar parameters derived from an EHe's UV spectrum are in satisfactory agreement with those derived from its optical spectrum. Adopted abundances for the seven EHes are from a combination of the UV and optical analyses. Published results for an additional ten EHes provide abundances obtained in a nearly uniform manner for a total of 17 EHes, the largest sample on record. The initial metallicity of an EHe is indicated by the abundance of elements from Al to Ni; Fe is adopted to be the representative of initial metallicity. Iron abundances range from approximately solar to about one-hundredth of solar. Clues to EHe evolution are contained within the H, He, C, N, O, Y, and Zr abundances. Two novel results are (i) the O abundance for some stars is close to the predicted initial abundance yet the N abundance indicates almost complete conversion of initial C, N, and O to N by the CNO-cycles; (ii) three of the seven stars with UV spectra show a strong enhancement of Y and Zr attributable to an s-process. The observed compositions are discussed in light of expectations from accretion of a He white dwarf by a CO white dwarf.Comment: 126 pages, 15 figures, 20 Tables, accepted for publication in the Ap

Cas9+ conditionally-immortalized macrophages as a tool for bacterial pathogenesis and beyond.

Macrophages play critical roles in immunity, development, tissue repair, and cancer, but studies of their function have been hampered by poorly-differentiated tumor cell lines and genetically-intractable primary cells. Here we report a facile system for genome editing in non-transformed macrophages by differentiating ER-Hoxb8 myeloid progenitors from Cas9-expressing transgenic mice. These conditionally immortalized macrophages (CIMs) retain characteristics of primary macrophages derived from the bone marrow yet allow for easy genetic manipulation and a virtually unlimited supply of cells. We demonstrate the utility of this system for dissection of host genetics during intracellular bacterial infection using two important human pathogens: Listeria monocytogenes and Mycobacterium tuberculosis

Possible Stellar Metallicity Enhancements from the Accretion of Planets

A number of recently discovered extrasolar planet candidates have surprisingly small orbits, which may indicate that considerable orbital migration takes place in protoplanetary systems. A natural consequence of orbital migration is for a series of planets to be accreted, destroyed, and then thoroughly mixed into the convective envelope of the central star. We study the ramifications of planet accretion for the final main sequence metallicity of the star. If maximum disk lifetimes are on the order of 10 Myr, stars with masses near 1 solar mass are predicted to have virtually no metallicity enhancement. On the other hand, early F and late A type stars with masses of 1.5--2.0 solar masses can experience significant metallicity enhancements due to their considerably smaller convection zones during the first 10 Myr of pre-main-sequence evolution. We show that the metallicities of an aggregate of unevolved F stars are consistent with an average star accreting about 2 Jupiter-mass planets from a protoplanetary disk having a 10 Myr dispersal time.Comment: 14 pages, AAS LaTeX, 3 figures, accepted to ApJ Letter

Direct measurement of molecular stiffness and damping in confined water layers

We present {\em direct} and {\em linear} measurements of the normal stiffness and damping of a confined, few molecule thick water layer. The measurements were obtained by use of a small amplitude (0.36 $\textrm{\AA}$), off-resonance Atomic Force Microscopy (AFM) technique. We measured stiffness and damping oscillations revealing up to 7 layers separated by 2.56 $\pm$ 0.20 $\textrm{\AA}$. Relaxation times could also be calculated and were found to indicate a significant slow-down of the dynamics of the system as the confining separation was reduced. We found that the dynamics of the system is determined not only by the interfacial pressure, but more significantly by solvation effects which depend on the exact separation of tip and surface. Thus ` solidification\rq seems to not be merely a result of pressure and confinement, but depends strongly on how commensurate the confining cavity is with the molecule size. We were able to model the results by starting from the simple assumption that the relaxation time depends linearly on the film stiffness.Comment: 7 pages, 6 figures, will be submitted to PR

The Sensitivity of Auditory-Motor Representations to Subtle Changes in Auditory Feedback While Singing

Singing requires accurate control of the fundamental frequency (F0) of the voice. This study examined trained singers’ and untrained singers’ (nonsingers’) sensitivity to subtle manipulations in auditory feedback and the subsequent effect on the mapping between F0 feedback and vocal control. Participants produced the consonant-vowel /ta/ while receiving auditory feedback that was shifted up and down in frequency. Results showed that singers and nonsingers compensated to a similar degree when presented with frequency-altered feedback (FAF); however, singers’ F0 values were consistently closer to the intended pitch target. Moreover, singers initiated their compensatory responses when auditory feedback was shifted up or down 6 cents or more, compared to nonsingers who began compensating when feedback was shifted up 26 cents and down 22 cents. Additionally, examination of the first 50 ms of vocalization indicated that participants commenced subsequent vocal utterances, during FAF, near the F0 value on previous shift trials. Interestingly, nonsingers commenced F0 productions below the pitch target and increased their F0 until they matched the note. Thus, singers and nonsingers rely on an internal model to regulate voice F0, but singers’ models appear to be more sensitive in response to subtle discrepancies in auditory feedback

Survival Rates in Trauma Patients Following Health Care Reform in Massachusetts

IMPORTANCE: Massachusetts introduced health care reform (HCR) in 2006, expecting to expand health insurance coverage and improve outcomes. Because traumatic injury is a common acute condition with important health, disability, and economic consequences, examination of the effect of HCR on patients hospitalized following injury may help inform the national HCR debate. OBJECTIVE: To examine the effect of Massachusetts HCR on survival rates of injured patients. DESIGN, SETTING, AND PARTICIPANTS: Retrospective cohort study of 1,520,599 patients hospitalized following traumatic injury in Massachusetts or New York during the 10 years (2002-2011) surrounding Massachusetts HCR using data from the State Inpatient Databases. We assessed the effect of HCR on mortality rates using a difference-in-differences approach to control for temporal trends in mortality. INTERVENTION: Health care reform in Massachusetts in 2006. MAIN OUTCOME AND MEASURE: Survival until hospital discharge. RESULTS: During the 10-year study period, the rates of uninsured trauma patients in Massachusetts decreased steadily from 14.9% in 2002 to 5.0.% in 2011. In New York, the rates of uninsured trauma patients fell from 14.9% in 2002 to 10.5% in 2011. The risk-adjusted difference-in-difference assessment revealed a transient increase of 604 excess deaths (95% CI, 419-790) in Massachusetts in the 3 years following implementation of HCR. CONCLUSIONS AND RELEVANCE: Health care reform did not affect health insurance coverage for patients hospitalized following injury but was associated with a transient increase in adjusted mortality rates. Reducing mortality rates for acutely injured patients may require more comprehensive interventions than simply promoting health insurance coverage through legislation

Discovery of Five New R Coronae Borealis Stars in the MACHO Galactic Bulge Database

We have identified five new R Coronae Borealis (RCB) stars in the Galactic bulge using the MACHO Project photometry database, raising the total number of known Galactic RCB stars to about 40. We have obtained spectra to confirm the identifications. The fact that four out of the five newly identified RCB stars are ``cool'' (T(eff) 6000 K) suggests that the preponderance of warm RCB stars among the existing sample is a selection bias. These cool RCB stars are redder and fainter than their warm counterparts and may have been missed in surveys done with blue plates. Based on the number of new RCB stars discovered in the MACHO bulge fields, there may be ~250 RCB stars in the reddened "exclusion" zone toward the bulge.Comment: 16 pages, 5 figures, AJ in press High resolution versions of Figures 1 and 2 can be downloaded from http://morpheus.phys.lsu.edu/~gclayton/figs.pdf (more typos corrected