22 research outputs found
HIV infection as a risk factor for shigellosis.
We investigated cases of shigellosis in San Francisco and Alameda Counties identified during 1996 by active laboratory surveillance to assess the role of HIV infection as a risk factor for shigellosis. Dramatically elevated rates of shigellosis in HIV-infected persons implicate HIV infection as an important risk factor for shigellosis in San Francisco
888-4 Angiotensin-converting enzyme inhibitors are comparable to angiotensin II receptor blockers in the primary prevention of myocardial infarction in hypertensive patients
888-4 Angiotensin-converting enzyme inhibitors are comparable to angiotensin II receptor blockers in the primary prevention of myocardial infarction in hypertensive patients
Rheumatoid arthritis is not associated with myocardial infarction after controlling for other risk factors
Nuclear Factor-κB Activation in Endothelium by Chlamydia pneumoniae without Active Infection
Causative molecular mechanisms accounting for the potential link between Chlamydia pneumoniae and atherosclerosis are unknown. Formalin and heat-inactivated C. pneumoniae activated the transcription factor nuclear factor (NF)-κB in cultured porcine endothelium and up-regulated the expression of E-selectin messenger RNA and protein. This up-regulation was abolished by an IκB super-repressor, an NF-κB-specific inhibitor. Live bacteria are not necessary for the activation of endothelial NF-κB, and C. pneumoniae may contribute to atherogenesis without active infection