Extensor medii proprius: A cadaveric case study

Abstract: During routine dissection of 11 cadavers that originated with the Body Donor Program at PCOM Georgia, a 69-year-old male with bilateral extensor anomalies in the dorsal forearm compartment was encountered. The distinct muscle belly, identified as the extensor medii proprius, originated from the distal ulna and inserted into the dorsal aponeurosis of the third digit. Manual traction of the right tendon resulted in extension of the third digit, suggesting functional significance of the anomalous muscle. This case study analyzes the extensor medii proprius found during dissection, its prevalence, embryologic origins, and clinical significance. The presence of the extensor medii proprius muscle and tendon must be considered when assessing pain in the dorsum of the hand and when preparing for surgical repair or tendon transfer

Operationalising and measuring language dominance

The paper offers a new way to measure language ability in bilinguals, based on measures of lexical richness. The validity of proposed approach is tested in a variety of ways

Sensor-Free or Sensor-Full: A Comparison of Data Modalities in Multi-Channel Affect Detection

ABSTRACT Computational models that automatically detect learners' affective states are powerful tools for investigating the interplay of affect and learning. Over the past decade, affect detectors-which recognize learners' affective states at run-time using behavior logs and sensor data-have advanced substantially across a range of K-12 and postsecondary education settings. Machine learningbased affect detectors can be developed to utilize several types of data, including software logs, video/audio recordings, tutorial dialogues, and physical sensors. However, there has been limited research on how different data modalities combine and complement one another, particularly across different contexts, domains, and populations. In this paper, we describe work using the Generalized Intelligent Framework for Tutoring (GIFT) to build multi-channel affect detection models for a serious game on tactical combat casualty care. We compare the creation and predictive performance of models developed for two different data modalities: 1) software logs of learner interactions with the serious game, and 2) posture data from a Microsoft Kinect sensor. We find that interaction-based detectors outperform posture-based detectors for our population, but show high variability in predictive performance across different affect. Notably, our posture-based detectors largely utilize predictor features drawn from the research literature, but do not replicate prior findings that these features lead to accurate detectors of learner affect

Water, women and disability: Using mixed-methods to support inclusive WASH programme design in Vanuatu.

BACKGROUND: Adequate access to water, sanitation and hygiene (WASH) is imperative for health and wellbeing, yet people with disabilities, people with incontinence and people who menstruate often experience unmet WASH requirements. METHODS: In 2019 we completed a mixed-methods study in two provinces of Vanuatu, (SANMA and TORBA). The study comprised 1) a population-based disability survey using the Washington Group Short-Set 2) a nested case-control study to explore associations between WASH, disability and gender, and 3) an in-depth qualitative assessment of the experiences of WASH users with additional requirements: people with and without disabilities who menstruate, or experience incontinence. FINDING: 11,446 households (response rate 85%) were enrolled into the survey. All-age disability prevalence across the two provinces was 2.6% (95% Confidence Interval 2.5-2.8), increasing with age. 814 people with, and 702 people without disabilities participated in the case-control study. People with disabilities were statistically more likely to experience barriers in seven of eight intra-household indicators. WASH-related stigma, reliance on informal caregivers, and under-resourcing of WASH personnel were critical issues for people who menstruate or experience incontinence. INTERPRETATION: People with disabilities, people with incontinence and people who menstruate in Northern Vanuatu face continued challenges in accessing safe, affordable and appropriate WASH that meets their requirements. Outputs from this study have supported progression towards gender and disability-inclusive WASH programming in the area and highlighted the value of mixed-methods research. FUNDING: The research was funded by the Australian Government's Water for Women fund and donations from the Australian public

"The weather is not good": exploring the menstrual health experiences of menstruators with and without disabilities in Vanuatu.

BACKGROUND: Menstrual health is essential for gender equality and achieving the sustainable development goals. Though currently lacking, understanding and addressing menstrual health and social related inequalities requires comparison of experiences between menstruators with and without disabilities. METHODS: We completed a mixed-methods population-based study of water, sanitation and hygiene, disability and menstrual health in TORBA and SANMA Provinces, Vanuatu. Methods included a census, nested case-control study, in-depth interviews (IDIs), focus group discussions (FGDs), PhotoVoice and structured observations. We undertook a population census of 11,000+ households and recruited 164 menstruators with and 169 without disabilities (aged 10-45) into a nested case-control study. 20 menstruators across both groups were selected for the qualitative component. FINDINGS: Menstruators with disabilities were five times (adjusted Odds Ratio [aOR] 5.5, 95% Confidence Interval 1.8 - 16.5) more likely to use different bathing facilities to others in the household, nearly twice as likely (1.8, 1.1 - 3.1) to miss social activities, and three times (3.0, 1.6 - 5.7) more likely to eat alone during menstruation. Menstrual restrictions were widespread for all, but collecting water and managing menstrual materials was harder for menstruators with disabilities, particularly those requiring caregivers' support. These factors negatively impacted menstruators with disabilities' comfort, safety and hygiene, yet they reported less interference of menstruation on participation. INTERPRETATION: Negative factors affecting all menstruators disproportionately impact those with disabilities, compounding existing inequalities. Menstruators with disabilities may have reported less interference because they are accustomed to greater participation restrictions than others. FUNDING: Australian Government's Water for Women fund and public donations

Combined 1H-Detected solid-state NMR spectroscopy and electron cryotomography to study membrane proteins across resolutions in native environments

Membrane proteins remain challenging targets for structural biology, despite much effort, as their native environment is heterogeneous and complex. Most methods rely on detergents to extract membrane proteins from their native environment, but this removal can significantly alter the structure and function of these proteins. Here, we overcome these challenges with a hybrid method to study membrane proteins in their native membranes, combining high-resolution solid-state nuclear magnetic resonance spectroscopy and electron cryotomography using the same sample. Our method allows the structure and function of membrane proteins to be studied in their native environments, across different spatial and temporal resolutions, and the combination is more powerful than each technique individually. We use the method to demonstrate that the bacterial membrane protein YidC adopts a different conformation in native membranes and that substrate binding to YidC in these native membranes differs from purified and reconstituted system

The Roles and Interactions of Symbiont, Host and Environment in Defining Coral Fitness

Background: Reef-building corals live in symbiosis with a diverse range of dinoflagellate algae (genus Symbiodinium) that differentially influence the fitness of the coral holobiont. The comparative role of symbiont type in holobiont fitness in relation to host genotype or the environment, however, is largely unknown. We addressed this knowledge gap by manipulating host-symbiont combinations and comparing growth, survival and thermal tolerance among the resultant holobionts in different environments.\ud Methodology/Principal Findings: Offspring of the coral, Acropora millepora, from two thermally contrasting locations, were experimentally infected with one of six Symbiodinium types, which spanned three phylogenetic clades (A, C and D), and then outplanted to the two parental field locations (central and southern inshore Great Barrier Reef, Australia). Growth and survival of juvenile corals were monitored for 31–35 weeks, after which their thermo-tolerance was experimentally assessed. Our results showed that: (1) Symbiodinium type was the most important predictor of holobiont fitness, as measured by growth, survival, and thermo-tolerance; (2) growth and survival, but not heat-tolerance, were also affected by local environmental conditions; and (3) host population had little to no effect on holobiont fitness. Furthermore, coral-algal associations were established with symbiont types belonging to clades A, C and D, but three out of four symbiont types belonging to clade C failed to establish a symbiosis. Associations with clade A had the lowest fitness and were unstable in the field. Lastly, Symbiodinium types C1 and D were found to be relatively thermo-tolerant, with type D conferring the highest tolerance in A. millepora.\ud Conclusions/Significance: These results highlight the complex interactions that occur between the coral host, the algal symbiont, and the environment to shape the fitness of the coral holobiont. An improved understanding of the factors affecting coral holobiont fitness will assist in predicting the responses of corals to global climate change

Factors affecting the establishment of a classical biological control agent, the horehound plume moth (Wheeleria spilodactylus) in South Australia / by Jeanine Baker.

Includes bibliographical references (leaves 168-198)xiv, 204 leaves ; 30 cm.The horehound plume moth (Wheeleria spilodactylus Curits), an agent introduced to control the invasive weed horehound (Murrubium vulgare L.), was used as a model system to investigate factors believed to influence the successful establishment of an introduced natural enemy. Retrospectively tests the use of generic population viability analysis and decision making tools for determining optimal release strategies for the horehound plume moth in South Australia and to compare outcomes with the emprical data collected during the course of this projectThesis (Ph.D.)--University of Adelaide, Dept. of Applied and Molecular Ecology, 200

Mass shootings in Australia and New Zealand: A descriptive study of incidence Mass shootings in Australia and New Zealand: A descriptive study of incidence

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