Demographic and Family Transition in Southeast Asia

This open access book presents the trends and patterns of demographic and family changes from all eleven countries in the region for the past 50 years. The rich data are coupled with historical, cultural and policy background to facilitate an understanding of the changes that families in Southeast Asia have been going through. The book is structured into two parts. Part A includes three segments preceded by a briefing on Southeast Asia. The first segment focuses on marital and partnership status in the region, particularly marriage rates, age at marriage, incidence of singlehood, cohabitation, and divorce. The second segment focuses on fertility indicators such as fertility rates (total, age-specific, adolescent), age at childbearing, and childlessness. The third presents information on household structures in the region by examining household sizes, and incidence of one-person households, single-parent families, as well as extended and composite households. Part B presents indicators of children and youth’s well-being

Demographic and Family Transition in Southeast Asia

This open access book presents the trends and patterns of demographic and family changes from all eleven countries in the region for the past 50 years. The rich data are coupled with historical, cultural and policy background to facilitate an understanding of the changes that families in Southeast Asia have been going through. The book is structured into two parts. Part A includes three segments preceded by a briefing on Southeast Asia. The first segment focuses on marital and partnership status in the region, particularly marriage rates, age at marriage, incidence of singlehood, cohabitation, and divorce. The second segment focuses on fertility indicators such as fertility rates (total, age-specific, adolescent), age at childbearing, and childlessness. The third presents information on household structures in the region by examining household sizes, and incidence of one-person households, single-parent families, as well as extended and composite households. Part B presents indicators of children and youth’s well-being

Children's Time With Fathers in Intact Families

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/73550/1/j.1741-3737.2001.00136.x.pd

Vapor Deposition of Highly Conformal Copper Seed Layers for Plating Through-Silicon Vias (TSVs)

Through-silicon vias (TSV) will speed up interconnections between chips. Manufacturable and cost-effective TSVs will allow faster computer systems. In this paper, we report the successful formation of seed layers for plating copper TSVs with aspect ratios greater than 25:1. Following the rapid atomic layer deposition (ALD) of a conformal insulating layer of silica inside the silicon vias, manganese nitride (Mn4N) is deposited conformally on the silica surface by chemical vapor deposition (CVD). Mn4N forms an effective copper diffusion barrier and provides strong adhesion between the silica and the subsequently-deposited copper. Conformal copper or copper-manganese alloy films are then deposited by an iodine-catalyzed direct-liquid-injection (DLI) CVD process. Diffusion of manganese during post-deposition annealing further enhances the barrier and adhesion properties at the copper/dielectric interfaceChemistry and Chemical Biolog

Adherence to the Mediterranean diet and body fat distribution in reproductive aged women

Background/Objectives Adherence to the Mediterranean Diet (MD) high in fruits, vegetables and monounsaturated fats, has been associated with lower body mass index. Associations with measured body fat, including regional adiposity, have not been previously investigated. We examined the associations between the alternate Mediterranean Diet Score (aMED), anthropometry and measured adiposity by dual energy x-ray absorptiometry. Subjects/Methods This study included 248 healthy females, aged 18–44 years from the BioCycle Study. Each woman’s aMED (range 0–9) was calculated from up to eight 24-hr dietary recalls over 1–2 menstrual cycles (>97% had ≥7 recalls). Multiple linear regression was used to determine whether aMED and its specific components were associated with total and regional adiposity after adjusting for age, race, education, physical activity and energy intake. Results: Participants had an average (SD) aMED of 4.2 (1.7) and percent body fat of 29.5 (6.0)%. Significant inverse associations were found between aMED and all the examined adiposity measures except waist to hip ratio. Among the DXA measures, a 1-unit increment in aMED was associated with a 0.06 (95% CI:−0.09,−0.02) lower trunk-to-leg fat ratio (T/L), a measure of upper to lower body fat. In an analysis examining T/L as an outcome with the separate components of the aMED, T/L was lower with increased legume consumption (β=−0.280, 95% CI:−0.550,−0.010) but was higher with increased consumption of red and processed meat (β=0.060, 95% CI:0.002,0.117). Conclusions: Adherence to the aMED was associated with lower total and regional adiposity, adding to the mounting evidence of the health benefits of the MD

Langevin PDF simulation of particle deposition in a turbulent pipe flow

The paper deals with the description of particle deposition on walls from a turbulent flow over a large range of particle diameter, using a Langevin PDF model. The first aim of the work is to test how the present Langevin model is able to describe this phenomenon and to outline the physical as- pects which play a major role in particle deposition. The general features and characteristics of the present stochastic model are first recalled. Then, results obtained with the standard form of the model are presented along with an analysis which has been carried out to check the sensitivity of the predictions on different mean fluid quantities. These results show that the physical repre- sentation of the near-wall physics has to be improved and that, in particular, one possible route is to introduce specific features related to the near-wall coherent structures. In the following, we propose a simple phenomenological model that introduces some of the effects due to the presence of turbulent coherent structures on particles in a thin layer close to the wall. The results obtained with this phenomenological model are in good agreement with experimental evidence and this suggests to pursue in that direction, towards the development of more general and rigorous stochastic models that provide a link between a geometrical description of turbulent flow and a statistical one.Comment: 40 pages, 8 figure

Parental Migration and Children's Psychological and Cognitive Development in China: Differences and Mediating Mechanisms

Internal migration has resulted in a large number of left-behind children in China. Despite growing attention to this population, important gaps remain in our understanding of their cognitive development and the factors that mediate the impact of migration on children. The present study draws on a new nationally representative survey of Chinese children to study the psychological and cognitive development of left-behind children. Results show that rural children left behind by both parents (but not by one parent) are worse off in both psychological well-being and cognitive development than rural children living with both parents. The disadvantage of left-behind children is mediated by their caregivers' emotional well-being, parenting practices, and education. We also find a pronounced rural-urban difference in children's cognitive development

Contribution of phosphatidylserine to membrane surface charge and protein targeting during phagosome maturation

During phagocytosis, the phosphoinositide content of the activated membrane decreases sharply, as does the associated surface charge, which attracts polycationic proteins. The cytosolic leaflet of the plasma membrane is enriched in phosphatidylserine (PS); however, a lack of suitable probes has precluded investigation of the fate of this phospholipid during phagocytosis. We used a recently developed fluorescent biosensor to monitor the distribution and dynamics of PS during phagosome formation and maturation. Unlike the polyphosphoinositides, PS persists on phagosomes after sealing even when other plasmalemmal components have been depleted. High PS levels are maintained through fusion with endosomes and lysosomes and suffice to attract cationic proteins like c-Src to maturing phagosomes. Phagocytic vacuoles containing the pathogens Legionella pneumophila and Chlamydia trachomatis, which divert maturation away from the endolysosomal pathway, are devoid of PS, have little surface charge, and fail to recruit c-Src. These findings highlight a function for PS in phagosome maturation and microbial killing

Unsupervised Bayesian linear unmixing of gene expression microarrays

Background: This paper introduces a new constrained model and the corresponding algorithm, called unsupervised Bayesian linear unmixing (uBLU), to identify biological signatures from high dimensional assays like gene expression microarrays. The basis for uBLU is a Bayesian model for the data samples which are represented as an additive mixture of random positive gene signatures, called factors, with random positive mixing coefficients, called factor scores, that specify the relative contribution of each signature to a specific sample. The particularity of the proposed method is that uBLU constrains the factor loadings to be non-negative and the factor scores to be probability distributions over the factors. Furthermore, it also provides estimates of the number of factors. A Gibbs sampling strategy is adopted here to generate random samples according to the posterior distribution of the factors, factor scores, and number of factors. These samples are then used to estimate all the unknown parameters. Results: Firstly, the proposed uBLU method is applied to several simulated datasets with known ground truth and compared with previous factor decomposition methods, such as principal component analysis (PCA), non negative matrix factorization (NMF), Bayesian factor regression modeling (BFRM), and the gradient-based algorithm for general matrix factorization (GB-GMF). Secondly, we illustrate the application of uBLU on a real time-evolving gene expression dataset from a recent viral challenge study in which individuals have been inoculated with influenza A/H3N2/Wisconsin. We show that the uBLU method significantly outperforms the other methods on the simulated and real data sets considered here. Conclusions: The results obtained on synthetic and real data illustrate the accuracy of the proposed uBLU method when compared to other factor decomposition methods from the literature (PCA, NMF, BFRM, and GB-GMF). The uBLU method identifies an inflammatory component closely associated with clinical symptom scores collected during the study. Using a constrained model allows recovery of all the inflammatory genes in a single factor