564 research outputs found

    Investigation of efficient multilevel inverter for photovoltaic energy system and electric vehicle applications

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    Introduction. This research presents a simple single-phase pulse-width modulated 7-level inverter topology for renewable system which allows home-grid applications with electric vehicle charging. Although multilevel inverters have appealing qualities, their vast range of application is limited by the use of more switches in the traditional arrangement. As a result, a novel symmetrical 7-level inverter is proposed, which has the fewest number of unidirectional switches with gate circuits, providing the lowest switching losses, conduction losses, total harmonic distortion and higher efficiency than conventional topology. The novelty of the proposed work consists of a novel modular inverter structure for photovoltaic energy system and electric vehicle applications with fewer numbers of switches and compact in size. Purpose. The proposed system aims to reduce switch count, overall harmonic distortions, and power loss. There are no passive filters required, and the constituted optimizes power quality by producing distortion-free sinusoidal output voltage as the level count increases while reducing power losses. Methods. The proposed topology is implemented with MATLAB/Simulink, using gating pulses and various pulse-width modulation methodologies. Moreover, the proposed model also has been validated and compared to the hardware system. Results. Total harmonic distortion, number of power switches, output voltage, current, power losses and number of DC sources are investigated with conventional topology. Practical value. The proposed topology has proven to be extremely beneficial for implementing photovoltaic-based stand-alone multilevel inverter and electric vehicle charging applications.Вступ. У цьому дослідженні представлена топологія простого семирівневого однофазного інвертора з широтно-імпульсною модуляцією для системи з відновлюваними джерелами енергії, яка дозволяє використовувати домашню мережу з зарядкою електромобілів. Хоча багаторівневі інвертори мають привабливі характеристики, широкий спектр їх застосування обмежений використанням більшої кількості перемикачів у традиційній схемі. В результаті запропонований новий симетричний 7-рівневий інвертор, який має найменшу кількість односпрямованих ключів із затворними ланцюгами, забезпечує найменші комутаційні втрати, втрати на провідність, сумарні гармонічні спотворення та вищий ККД, ніж традиційна топологія. Новизна запропонованої роботи полягає у новій модульній структурі інвертора для фотоелектричних енергетичних систем та використання для електромобілів з меншою кількістю перемикачів та компактними розмірами. Мета. Пропонована система спрямована на зменшення кількості перемикань, загальних гармонічних спотворень та втрат потужності. Пасивні фільтри не потрібні, а складова частина оптимізує якість електроенергії, створюючи синусоїдальну вихідну напругу без спотворень зі збільшенням кількості рівнів при одночасному зниженні втрат потужності. Методи. Запропонована топологія реалізована за допомогою MATLAB/Simulink з використанням стробуючих імпульсів та різних методологій широтно-імпульсної модуляції. Крім того, запропонована модель також була перевірена та порівняна з апаратною системою. Результати. Загальні гармонічні спотворення, кількість силових ключів, вихідна напруга, струм, втрати потужності та кількість джерел постійного струму досліджуються за допомогою традиційної топології. Практична цінність. Запропонована топологія виявилася надзвичайно корисною для реалізації автономних багаторівневих інверторів на основі фотоелектричних систем та застосування для заряджання електромобілів

    DOF phase separation of the Lennard-Jones fcc(111) surface

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    Recent lattice model calculations have suggested that a full-layered crystal surface may undergo, under canonical (particle-conserving) conditions, a preroughening-driven two-dimensional phase separation into two disordered flat (DOF) regions, of opposite order parameter. We have carried out extensive classical molecular dynamics (MD) simulations of the Lennard-Jones fcc(111) surface, to check whether these predictions are relevant or not for a realistic continuous system. Very long simulation times, a grid of temperatures from (2/3)Tm to Tm, and unusually large system sizes are employed to ensure full equilibrium and good statistics. By examining layer-by-layer occupancies, height fluctuations, sublattice order parameter and X-ray structure factors, we find a clear anomaly at ~0.83Tm. The anomaly is distinct from roughening (whose incipiency is also detected at ~0.94Tm), and is seen to be consistent with the preroughening plus phase separation scenario.Comment: REVTeX, 8 pages, 4 figures; new figure showing simulation snapshots added; reference updated and other minor change

    Methamphetamine Self-Administration Is Associated with Persistent Biochemical Alterations in Striatal and Cortical Dopaminergic Terminals in the Rat

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    Methamphetamine (meth) is an illicit psychostimulant that is abused throughout the world. Repeated passive injections of the drug given in a single day or over a few days cause significant and long-term depletion of dopamine and serotonin in the mammalian brain. Because meth self-administration may better mimic some aspects of human drug-taking behaviors, we examined to what extent this pattern of drug treatment might also result in damage to monoaminergic systems in the brain. Rats were allowed to intravenously self-administer meth (yoked control rats received vehicle) 15 hours per day for 8 days before being euthanized at either 24 hours or at 7 and 14 days after cessation of drug taking. Meth self-administration by the rats was associated with a progressive escalation of daily drug intake to 14 mg/kg per day. Animals that self-administered meth exhibited dose-dependent decreases in striatal dopamine levels during the period of observation. In addition, there were significant reductions in the levels of striatal dopamine transporter and tyrosine hydroxylase proteins. There were also significant decreases in the levels of dopamine, dopamine transporter, and tyrosine hydroxylase in the cortex. In contrast, meth self-administration caused only transient decreases in norepinephrine and serotonin levels in the two brain regions, with these values returning to normal at seven days after cessation of drug taking. Importantly, meth self-administration was associated with significant dose-dependent increases in glial fibrillary acidic protein in both striatum and cortex, with these changes being of greater magnitude in the striatum. These results suggest that meth self-administration by rats is associated with long-term biochemical changes that are reminiscent of those observed in post-mortem brain tissues of chronic meth abusers

    Energy spectrum and the absolute flux of various celestial X-ray sources

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    The results on the flux of low energy X-rays in the range 2-18 Kev from Sco-X1, Tau-X1 and Cen-X2 celestial sources observed during two rocket flights, flown from the Thumba Equatorial Rocket Launching Station (TERLS), Trivandrum, India, are presented. The absolute flux and the energy spectrum obtained for these sources are compared with other similar observations. The results indicate a long-term exponential decrease in the energy flux of X-rays from Sco-X1 over the period 1965-1968. The X-ray source Cen-X2, which showed a remarkable outburst of X-rays in April 1967, had ceased to be active after May 1967. We present here the first evidence of the rediscovery of the low energy, X-ray flux from Cen-X2 since May 1967. These short-lived X-ray out-bursts may be attributed to a shock wave from the nova outburst expanding into the circumstellar medium

    Issues in solid-organ transplantation in children: translational research from bench to bedside

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    In this review, we identify important challenges facing physicians responsible for renal and cardiac transplantation in children based on a review of the contemporary medical literature. Regarding pediatric renal transplantation, we discuss the challenge of antibody-mediated rejection, focusing on both acute and chronic antibody-mediated rejection. We review new diagnostic approaches to antibody-mediated rejection, such as panel-reactive antibodies, donor-specific cross-matching, antibody assays, risk assessment and diagnosis of antibody-mediated rejection, the pathology of antibody-mediated rejection, the issue of ABO incompatibility in renal transplantation, new therapies for antibody-mediated rejection, inhibiting of residual antibodies, the suppression or depletion of B-cells, genetic approaches to treating acute antibody-mediated rejection, and identifying future translational research directions in kidney transplantation in children. Regarding pediatric cardiac transplantation, we discuss the mechanisms of cardiac transplant rejection, including the role of endomyocardial biopsy in detecting graft rejection and the role of biomarkers in detecting cardiac graft rejection, including biomarkers of inflammation, cardiomyocyte injury, or stress. We review cardiac allograft vasculopathy. We also address the role of genetic analyses, including genome-wide association studies, gene expression profiling using entities such as AlloMap®, and adenosine triphosphate release as a measure of immune function using the Cylex® ImmuKnow™ cell function assay. Finally, we identify future translational research directions in heart transplantation in children

    Forecasting and Monitoring Intense Thunderstorms in the Hindu Kush Himalayan Region: Spring 2018 Forecasting Experiment

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    Some of the most intense thunderstorms on the planet occur in the Hindu Kush Himalayan (HKH) region of South Asia - where many organizations lack the capacity needed to predict, observe and/or effectively respond to the threats associated with high-impact convective weather. Among the hazards include tornadoes, damaging straight-line winds (known as Nor'westers in the HKH region), large hail, and flash flooding, which typically peak in the pre-wet-monsoon season. Previous studies have documented a disproportionately large number of casualties associated with intense thunderstorms in this region; therefore, the goal of this project is to increase situational awareness of these hazards through short-term modeling and satellite assessment tools
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